Clinical trials
Weaning Invasive Mechanical Ventilation clinical trials
Below are recruiting weaning invasive mechanical ventilation clinical trials, each written for real people, not researchers. We’re tracking 30 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT07761468Enrolling by invitation
Standardized medication dosing for ICU patients on ventilators
This study is testing a standardized way to adjust a medication used to help people on ventilators in the ICU. It aims to see if a more consistent dosing approach can help patients breathe better and possibly come off the ventilator sooner.
Querétaro City, QuerétaroAges 18 years+ - NCT07751237Recruiting
Ultrasound of the diaphragm during breathing machine weaning
This study uses ultrasound to look at how well your diaphragm (the main breathing muscle) is working while you are on a breathing machine. The goal is to see if this can help doctors predict when you can safely breathe on your own and leave the ventilator sooner.
Porto Alegre, Rio Grande do SulAges 18 years+ - NCT06450678Recruiting
Can a physiotherapy test predict breathing tube removal success?
This study checks if a quick physical therapy exam can predict whether a person will need the breathing machine again after it is removed. It is for adults who have been on a ventilator for more than two days and have already shown they can breathe on their own for a short time.
ParisAges 18 years+ - NCT07105202RecruitingPhase 4
Shorter weaning from ventilator with levosimendan
This study tests if a heart medication called levosimendan helps people get off the breathing machine (ventilator) faster. It's for people who have been on a ventilator for more than 48 hours and have already tried and failed to breathe on their own.
Arnhem, GelderlandAges 18 years+ - NCT06655805Recruiting
Registry for automated breathing support in adults
This trial collects data from adults in the ICU who need oxygen therapy, non-invasive ventilation, or a breathing tube with a machine. It looks at how automated settings affect care.
Sankt Gallen, Canton of St. GallenAges 18 years+ - NCT06923267Recruiting
Ultrasound to check heart function during breathing trials
This trial tests if using ultrasound to monitor your heart during a breathing test can help predict if you will need the breathing tube again. It is for people on a ventilator for at least 24 hours who are at higher risk of needing the tube reinserted.
OrléansAges 18 years+ - NCT07130123Recruiting
Endotracheal suction during extubation in the ICU
This study compares different methods of suctioning the breathing tube during extubation (removal of the tube) in patients who have been on a ventilator for more than 48 hours. It aims to find the best way to clear the airway while taking the tube out.
Orléans, LoiretAges 18 years+ - NCT07455214Recruiting
Heart rate variability and breathing trial success in ventilated patients
This study looks at whether heart rate patterns can help predict if a person on a breathing machine is ready to breathe on their own. It may help doctors decide the best time to try removing the breathing tube.
New Taipei CityAges 18–85 - NCT06464224Recruiting
Breathing effort patterns in patients coming off the ventilator
This study observes how your breathing effort changes as doctors try to remove you from the breathing machine (ventilator). It helps understand why some patients have trouble breathing on their own after being on the ventilator.
Rio de JaneiroAges 18 years+ - NCT04080440Recruiting
Checking readiness to remove the breathing tube after brain injury
This study looks at how to judge when it is safe to remove the breathing tube in people in the ICU after a brain injury. It may help improve timing and safety of extubation, when supported by a breathing trial and clinical stability.
AngersAges 18–75 - NCT06609577Recruiting
Ultrasound-guided diaphragm pacing for patients on ventilators
This trial tests a personalized pacing device that uses ultrasound to help your diaphragm muscle work better while you are on a breathing machine. It may help you breathe on your own sooner and improve your recovery.
Nantong, JiangsuAges 18–95 - NCT06754670Recruiting
How low phosphate affects breathing after ventilator use
This study looks at how low phosphate levels in the blood affect your ability to breathe on your own when coming off a ventilator. If you are already getting better and ready to start breathing without the machine, the results may help doctors understand and manage your recovery better.
BeijingAges 18 years+ - NCT06776939Recruiting
High-flow oxygen through trach tube to help weaning from a ventilator
This trial tests if high-flow oxygen delivered through a tracheostomy tube can make mucus less sticky and reduce breathing effort while you are being taken off a ventilator. It could help you breathe easier during weaning.
RotterdamAges 18 years+ - NCT07098611Recruiting
New tool to predict readiness for breathing tube removal
This study tests a new scoring tool to help doctors decide when a patient on a breathing machine is ready to have the tube removed safely. It is for patients who are currently in the process of being weaned off the ventilator.
Punta ArenasAges 18–89 - NCT07571317Recruiting
Predicting breathing tube removal success in ICU patients
This study tests whether two simple breathing measurements can predict whether patients in the ICU are ready to have their breathing tube removed. If successful, it could help doctors make safer decisions about when patients can breathe on their own.
Istanbul, IstanbulAges 18 years+ - NCT07432191Recruiting
Testing a new ventilator for safe breathing support
This study tests a new breathing machine (INBENTUS VERSATILE ventilator) for people who need help breathing. It checks if the machine is safe and works well for patients who need a ventilator and then slowly come off it.
MurciaAges 18 years+ - NCT07590362Recruiting
Testing breathing readiness measures in ventilated COPD patients
This study compares two methods of measuring whether patients with COPD who are on breathing machines are ready to breathe on their own. The goal is to find the best way to predict which patients can successfully come off the ventilator.
Sohag, Sohag GovernorateAges 18 years+ - NCT06837402Enrolling by invitation
Non-invasive ventilation in Argentine ICUs: an observational study
This study looks at how non-invasive breathing support (like a mask or machine) is used in ICUs across Argentina. It helps doctors understand patterns of care so they can improve treatment for patients with breathing problems.
CABA, Buenos AiresAges 18 years+ - NCT06542107Recruiting
Weaning from a breathing machine after brain injury
This study looks at the best way to help people with a recent brain injury come off a breathing machine (ventilator). It aims to improve the weaning process and reduce time on the ventilator.
Nanjing, JiangsuAges 18 years+ - NCT05710432Recruiting
Exercises to help breathing during ventilator weaning
This study tests whether specific neck and breathing muscle exercises during ventilator weaning can help people breathe more effectively and safely come off the ventilator. It may help patients who have already had trouble with prior weaning attempts.
Toronto, OntarioAges 16 years+ - NCT06579157Recruiting
Using pressure-sensing mattresses to help newborns breathe on their own
This trial tests whether a special mattress that senses breathing movements can help doctors decide when to remove breathing support from newborns. It may reduce the time babies need a breathing machine.
New Taipei CityAges Up to 1 year - NCT06867354Recruiting
Breathing difficulty in obese patients during weaning from ventilator
This study looks at how often obese patients have trouble breathing when doctors try to remove the breathing tube (weaning) in the ICU. The goal is to understand what causes this and how it affects recovery.
Paris, ParisAges 18 years+ - NCT07073976Recruiting
Predicting success of coming off the breathing machine using heart ultrasound
This study uses an ultrasound of the heart (echocardiogram) to check how well the right side of your heart is working. The goal is to see if that can help predict whether you will successfully come off the breathing machine.
Istanbul, IstanbulAges 18 years+ - NCT06835842Recruiting
Rib mobilization for pneumonia patients on a ventilator
This study tests whether a gentle rib movement technique (called rib mobilization) can help people with pneumonia who are on a breathing machine get ready to breathe on their own. It aims to see if this therapy makes it easier to wean off the ventilator.
CairoAges 40–50
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Common questions
- Are there clinical trials for weaning invasive mechanical ventilation?
- Yes. Clin2 currently lists 30 recruiting weaning invasive mechanical ventilation studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a weaning invasive mechanical ventilation trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a weaning invasive mechanical ventilation trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.