Clinical trials
Weaning Failure of Mechanical Ventilation clinical trials
Below are recruiting weaning failure of mechanical ventilation clinical trials, each written for real people, not researchers. We’re tracking 34 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT07751237Recruiting
Ultrasound of the diaphragm during breathing machine weaning
This study uses ultrasound to look at how well your diaphragm (the main breathing muscle) is working while you are on a breathing machine. The goal is to see if this can help doctors predict when you can safely breathe on your own and leave the ventilator sooner.
Porto Alegre, Rio Grande do SulAges 18 years+ - NCT06450678Recruiting
Can a physiotherapy test predict breathing tube removal success?
This study checks if a quick physical therapy exam can predict whether a person will need the breathing machine again after it is removed. It is for adults who have been on a ventilator for more than two days and have already shown they can breathe on their own for a short time.
ParisAges 18 years+ - NCT07019636Recruiting
Direct extubation vs. extubation after a breathing trial
This study compares two ways of removing the breathing tube (extubation) in patients who are ready to breathe on their own: taking the tube out right away, or doing a trial of breathing without the machine first. It is for people who are at low risk of needing the tube put back in.
ParisAges 18–65 - NCT06683781Recruiting
Breathing machine settings and weaning success study
This study looks at how breathing machine settings and monitoring can help predict if a patient will successfully come off the ventilator. It may help doctors choose better settings for patients who are ready to try breathing on their own.
Buenos AiresAges 18–100 - NCT06391424Recruiting
Oxygen use and breathing effort during ventilator weaning
If you are on a breathing machine in the ICU and ready to try breathing on your own, this study looks at how much oxygen your body uses during that test. It may help doctors better understand when you are ready to come off the ventilator.
Leiden, South HollandAges 18 years+ - NCT04658498Recruiting
Respiratory muscle training to help patients come off the ventilator
This trial studies whether exercises for breathing muscles can help people who are having a hard time coming off a breathing machine in the ICU. It may help you breathe with less ventilator support once your body is stable enough.
LeuvenAges 18 years+ - NCT07109570Recruiting
Checking breathing effort in ICU patients on a ventilator
This trial measures how your breathing muscles work while we try taking you off the breathing machine. The results could help doctors predict when you're ready to breathe on your own.
LeidenAges 18 years+ - NCT03657524Recruiting
Ultrasound heart imaging to help predict trouble weaning off a ventilator
This study uses a special ultrasound of the heart to help predict whether you might fail a trial of breathing on your own after being on a breathing machine. If the test can predict trouble early, clinicians may choose safer weaning plans.
MarseilleAges 18 years+ - NCT07075926Recruiting
Heart ultrasound to predict breathing tube removal success in ICU
This study uses a heart ultrasound to see if it can help doctors predict when patients in the ICU are ready to have their breathing tube removed. It may help avoid failed extubations and reduce complications.
Istanbul, IstanbulAges 18 years+ - NCT07073976Recruiting
Predicting success of coming off the breathing machine using heart ultrasound
This study uses an ultrasound of the heart (echocardiogram) to check how well the right side of your heart is working. The goal is to see if that can help predict whether you will successfully come off the breathing machine.
Istanbul, IstanbulAges 18 years+ - NCT07105202RecruitingPhase 4
Shorter weaning from ventilator with levosimendan
This study tests if a heart medication called levosimendan helps people get off the breathing machine (ventilator) faster. It's for people who have been on a ventilator for more than 48 hours and have already tried and failed to breathe on their own.
Arnhem, GelderlandAges 18 years+ - NCT06923267Recruiting
Ultrasound to check heart function during breathing trials
This trial tests if using ultrasound to monitor your heart during a breathing test can help predict if you will need the breathing tube again. It is for people on a ventilator for at least 24 hours who are at higher risk of needing the tube reinserted.
OrléansAges 18 years+ - NCT07363902Recruiting
Electrical muscle stimulation study for breathing support
This study tests a new device that uses mild electrical pulses to strengthen the muscles used for breathing in people who are on a ventilator. It aims to help them recover faster.
Barcelona, BarcelonaAges 18 years+ - NCT07445035Recruiting
Robotic leg brace to help walking while on a breathing machine
This study tests whether walking with a robotic leg brace (exoskeleton) can help people who are on a breathing machine get better faster. It is for adults in the intensive care unit who can sit, stand with help, and have no major leg or heart problems.
New Taipei CityAges 45–65 - NCT06464224Recruiting
Breathing effort patterns in patients coming off the ventilator
This study observes how your breathing effort changes as doctors try to remove you from the breathing machine (ventilator). It helps understand why some patients have trouble breathing on their own after being on the ventilator.
Rio de JaneiroAges 18 years+ - NCT06424314Recruiting
Trial on why some patients fail to come off a ventilator
This trial is studying why some people have trouble coming off a breathing machine (ventilator). It's for patients who've been on a ventilator for at least 2 days and don't have certain other conditions.
Guangzhou, GuangdongAges 18 years+ - NCT07467265Recruiting
Testing a breathing test to safely remove ventilators
This study is testing a simple way to measure how well you breathe on your own when coming off a ventilator in the ICU. It helps doctors decide the best time to safely remove the breathing tube.
Cairo, AbbasiaAges 22 years+ - NCT07003672Recruiting
Weaning from ventilator: a lung measurement study
This study looks at people who have a tracheostomy and have been on a breathing machine for at least two weeks. Researchers want to see if certain lung measurements can help predict how easy or hard it will be to come off the ventilator.
TaipeiAges 20 years+ - NCT07177183Recruiting
Low creatinine as a sign of longer breathing tube use
This study looks at whether low blood creatinine levels can help predict which patients will need a breathing machine for a long time or have trouble coming off it. If you are under 18 and in a post-ICU care unit, you may be able to join.
BrnoAges 18 years+ - NCT04080440Recruiting
Checking readiness to remove the breathing tube after brain injury
This study looks at how to judge when it is safe to remove the breathing tube in people in the ICU after a brain injury. It may help improve timing and safety of extubation, when supported by a breathing trial and clinical stability.
AngersAges 18–75 - NCT05751863Recruiting
Sedation-first vs usual care in ventilated trauma patients
This study compares how pain medicine and calming medicine are started in critically injured (trauma) adults who are on a breathing machine. It aims to see whether a specific “analgesia-first” approach can improve comfort and support breathing weaning.
Long Beach, CaliforniaAges 18 years+ - NCT05990348Recruiting
Comparing two breathing support methods for weaning from ventilator
This study compares two ways of helping patients breathe on a ventilator after a failed attempt to come off the machine. It looks at how the diaphragm and rib muscles work during each method to find the best approach for weaning.
RomeAges 18 years+ - NCT06609577Recruiting
Ultrasound-guided diaphragm pacing for patients on ventilators
This trial tests a personalized pacing device that uses ultrasound to help your diaphragm muscle work better while you are on a breathing machine. It may help you breathe on your own sooner and improve your recovery.
Nantong, JiangsuAges 18–95 - NCT06754670Recruiting
How low phosphate affects breathing after ventilator use
This study looks at how low phosphate levels in the blood affect your ability to breathe on your own when coming off a ventilator. If you are already getting better and ready to start breathing without the machine, the results may help doctors understand and manage your recovery better.
BeijingAges 18 years+
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Common questions
- Are there clinical trials for weaning failure of mechanical ventilation?
- Yes. Clin2 currently lists 34 recruiting weaning failure of mechanical ventilation studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a weaning failure of mechanical ventilation trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a weaning failure of mechanical ventilation trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.