Clinical trials
Metabolic Disease clinical trials
Below are recruiting metabolic disease clinical trials, each written for real people, not researchers. We’re tracking 366 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT06546020Recruiting
Haskap berries for gut and metabolic health
This study tests whether a berry called Haskap can improve your gut health and how that might affect your overall health. Researchers are looking for people with and without certain metabolic risk factors to see who benefits most from adding these berries to their diet.
Bozeman, MontanaAges 35–65 - NCT06550115Recruiting
Night shift workers and their blood vessel & sugar health
This trial studies how sleep patterns affect blood vessel health and sugar control in long-term night shift workers. It may help find better ways to prevent heart problems and diabetes.
Fort Collins, ColoradoAges 18–65 - NCT06568471RecruitingPhase 3
Study of HST101 for high cholesterol in Chinese patients
This study tests a new injectable medication called HST101 for lowering cholesterol in people who are already taking cholesterol pills but still have high levels. It may help if you have heart disease or are at high risk.
Beijing, Beijing MunicipalityAges 18 years+ - NCT07575932RecruitingPhase 2
Testing New Weight Loss Medications PF-08653945 and PF-08653944
This study tests two new experimental medications designed to help adults lose weight and improve weight-related health conditions like high blood pressure and sleep apnea. Participants will take one of these medications to see if it's safe and effective.
Chandler, ArizonaAges 18 years+ - NCT06790225Recruiting
A study on a gut hormone and bone health
This trial looks at how a natural gut hormone (GIP) affects bone remodeling in healthy people. If you are healthy, you may help us understand how this hormone works on bone cells.
EsbjergAges 18–40 - NCT06833554Recruiting
Breast milk cells and infant health in mothers with metabolic conditions
This trial studies how special cells in breast milk from mothers with metabolic diseases (like obesity or diabetes) affect infant development and lung infection response after a nutritional intervention. It aims to understand if improving mother's diet can strengthen baby's immune system.
Málaga, MalagaAges 18–50 - NCT06843902RecruitingPhase 2
Improving heart blood flow in women with HIV
This study is testing a medication that may help improve blood flow to the heart in women with HIV who also have diabetes, kidney disease, or protein in their urine. You would need to have a heart scan that shows low blood flow and not be taking certain diabetes drugs.
Boston, MassachusettsAges 45–75 - NCT06923644Recruiting
Personalized nutrition plan to prevent metabolic disease
This study tests whether a personalized nutrition plan based on your unique metabolism can help prevent chronic metabolic diseases like type 2 diabetes. You will follow a tailored diet and have your health monitored over time.
MaastrichtAges 40–75 - NCT07036692Recruiting
Weight loss study for adults with extra weight and health risks
This study tests a simple plan to help people with overweight and related health risks lose weight over a long time. You would follow the plan at home, chew a special gum, and send in a stool sample to see how your gut health changes.
BernAges 25 years+ - NCT07124949Recruiting
Chinese migrant health study for older adults
This long-term study follows adults aged 60 and older who live in Harbin or Hainan to track their health over five years. It aims to understand health changes in this migrant population and does not involve any new treatments or drugs.
Harbin, HeilongjiangAges 60–120 - NCT07215533Recruiting
Exercise trials for teens and young adults at risk for diabetes
This study compares two types of exercise—high-intensity interval training (HIIT) and time-restricted eating (TRE)—to help lower the risk of developing type 2 diabetes in teens and young adults who are overweight or have obesity.
Syracuse, New YorkAges 14–30 - NCT00920972RecruitingPhase 1/Phase 2
Bone marrow transplant prep for children with non-cancer blood disorders
This early-stage study tests a specific chemotherapy “conditioning” regimen to prepare the body for a bone marrow transplant in children with certain non-cancer blood or immune conditions. It may help the transplant work better, but it also carries risks from the chemotherapy and transplant process.
Phoenix, ArizonaAges Up to 20 years - NCT07417124RecruitingPhase 1
Safety of SNS851 in healthy volunteers
This early-phase trial tests a new investigational drug called SNS851 in healthy volunteers to see if it is safe and how the body handles it. It is a first step in understanding this treatment before testing it in people with a disease.
MelbourneAges 18–55 - NCT07669168Recruiting
Health study comparing usual care vs. extra support
This study looks at whether adding extra health support helps people stay healthier over time. You would be followed for a while and asked to share how you are doing.
Boulder, ColoradoAges 18 years+ - NCT06966258Recruiting
Heart health program for Black women in Birmingham
This trial tests a program called Inspire HER, which aims to improve heart and emotional health for Black women with early-stage cardiovascular-kidney-metabolic syndrome. You may qualify if you have this condition and live in the Birmingham area.
Birmingham, AlabamaAges 30–79 - NCT05275608Recruiting
Low-carb diet effects in people with metabolic syndrome
This trial studies whether a very low-calorie, low-carb diet (VLCKD) can improve metabolic health in adults with metabolic syndrome, fatty liver, and type 2 diabetes. It may help lower blood sugar and improve related health markers if you fit their specific diabetes and liver/kidney criteria.
Novara, ItalyAges 25–65 - NCT07241195Recruiting
Fatty Liver Study in Older Adults
This study follows older adults with fatty liver disease to understand how their metabolism changes over time and how it affects their overall health. It helps researchers learn more about the condition and its impact on the body outside the liver.
Hangzhou, ZhejiangAges 65–100 - NCT06729554Recruiting
Education and support program for rare disease kids
This study tests a targeted educational and support program for children and teens with rare diseases. It helps families learn more about the condition and cope better with day-to-day challenges.
Graz, AustriaAges 5–20 - NCT07707778Enrolling by invitationPhase 4
Tirzepatide for Weight and Aging in People with HIV
This trial tests whether a weight-loss medicine called tirzepatide can slow biological aging and improve metabolism in people with HIV who are already on effective treatment. It may help you reduce weight and possibly reverse some signs of aging.
TaipeiAges 18 years+ - NCT06541132Recruiting
Liver fat and heart artery narrowing study
This study looks at whether the amount of fat in your liver, seen on an ultrasound, is linked to the severity of narrowing in your heart arteries. If you had a heart catheterization (angiography) and an abdominal ultrasound, your data may help researchers understand this connection.
Chongqing, Chongqing MunicipalityAges 18–90 - NCT06706856Recruiting
Ultrasound test for fatty liver disease in kids
This study explores if a new ultrasound technique can detect fatty liver disease in children. It aims to find a simpler, safer way to check liver health without needing an MRI or biopsy.
La Jolla, CaliforniaAges 9–18 - NCT07652151Recruiting
Fatty Liver Disease Study Using Wearable Tracking
This research studies fatty liver disease linked to metabolic problems like diabetes and obesity. You'll wear a fitness tracker and have liver imaging to help doctors understand the disease and find new treatments.
RomaAges 18 years+ - NCT05519475RecruitingPhase 2
Gene-silencing medicine trial for adults with MASH and liver scarring
This Phase 2 study tests a gene-silencing treatment to improve chronic liver disease called MASH, especially in people with certain genetic risk. You may be eligible if you have MASH with moderate-to-advanced scarring and specific test results, and if other liver causes and recent substance/alcohol issues don’t apply.
Chandler, ArizonaAges 18–75 - NCT03152617Recruiting
Study on nutrition and mouth health risks after obesity treatment
This trial looks at risks like malnutrition, weak bones, and oral (mouth) health problems after obesity treatment. It may help improve follow-up care for people who receive specialist treatment or weight-loss surgery.
GothenburgAges 18 years+
Hear when a new Metabolic Disease trial opens
We’ll email you when one opens — at most once a week, no account needed, unsubscribe anytime.
Common questions
- Are there clinical trials for metabolic disease?
- Yes. Clin2 currently lists 366 recruiting metabolic disease studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a metabolic disease trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a metabolic disease trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.