Clinical trials
Metastasis clinical trials
Below are recruiting metastasis clinical trials, each written for real people, not researchers. We’re tracking 343 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT06111105Recruiting
Comparing blood tests to guide colon cancer treatment
This study compares different blood tests to find the best way to detect tiny bits of cancer DNA after surgery for stage III colorectal cancer. It aims to help doctors decide if additional chemotherapy is needed to prevent the cancer from coming back.
Graz, StyriaAges 18 years+ - NCT06126419Recruiting
High-dose insulin for liver function after surgery
This trial tests if high-dose insulin can help your liver work better and heal faster after a major liver surgery for colorectal cancer that has spread to the liver.
Montreal, QuebecAges 18 years+ - NCT06130280RecruitingPhase 2
MRI-guided radiation for liver tumors from colorectal cancer
This trial tests a single, high-dose radiation treatment (SBRT) guided by MRI for people with colorectal cancer that has spread to the liver. The goal is to see if this precise, one-time treatment can effectively control liver tumors while protecting nearby organs.
Basking Ridge, New JerseyAges 18 years+ - NCT06135714RecruitingPhase 3
Targeting limited breast cancer spread with focused therapy
This trial tests whether treating just the few spots where breast cancer has spread (called oligometastases) with radiation or surgery can help control the disease. It is for people whose cancer has spread to 3 or fewer places, each small in size, and who are healthy enough for local treatments.
Tokyo, TokyoAges 18–80 - NCT06159335RecruitingPhase 3
PET/MR scan for brain metastasis imaging
This trial uses a special PET/MR scan with a radioactive tracer to help tell the difference between tumor regrowth and changes from radiation treatment in people with brain metastases. It may help doctors make better treatment decisions.
Madison, WisconsinAges 18 years+ - NCT06165419RecruitingPhase 2
High-dose radiation for spine metastases from solid tumors
This trial tests a new way of giving high-dose radiation to solid tumors that have spread to the spine. It is for people whose spine is stable, have not had prior treatment to that area, and have only minor weakness (if any).
Stony Brook, New YorkAges 18 years+ - NCT06171750RecruitingPhase 1
Study of ANK-101 for advanced solid tumors
This trial tests a new drug, ANK-101, injected directly into tumors to help fight advanced solid tumors that have spread or can't be treated with standard therapies. It may be an option if you have a tumor that can be reached for injection.
Bethesda, MarylandAges 18 years+ - NCT06179602Recruiting
Study of thermal ablation for liver tumors
This study follows patients who are having a procedure called thermal ablation to treat liver tumors. It aims to learn more about how well the procedure works and how safe it is.
LeidenAges 18–110 - NCT06185556RecruitingPhase 2/Phase 3
New treatments for liver tumors near blood vessels or bile ducts
This trial tests two procedures—irreversible electroporation and stereotactic body radiotherapy—for people whose colorectal cancer has spread to the liver (1–3 tumors near major blood vessels or bile ducts) and can't be surgically removed or treated with heat. The goal is to see if these approaches can safely destroy those hard-to-reach tumors.
Amsterdam, North HollandAges 18 years+ - NCT06200831Recruiting
Same surgery or two surgeries for colorectal cancer with liver spread
This trial compares having one surgery to remove both the colon tumor and liver tumors at the same time versus having two separate surgeries. It aims to find which approach is safer and works better for patients whose cancer has spread only to the liver.
OsloAges 18–80 - NCT06216938RecruitingEarly Phase 1
RP1 virus therapy for advanced melanoma to lower lymph node spread risk
This trial tests a new kind of virus-based treatment (RP1) given directly into melanoma tumors to see if it can reduce the chance of cancer spreading to nearby lymph nodes. It's for people with thicker or more advanced skin melanoma that still has visible tumor or positive margins after biopsy.
Pittsburgh, PennsylvaniaAges 18 years+ - NCT06225843RecruitingPhase 2
Testing a new drug combo before liver surgery for colorectal cancer
This trial is for people with colorectal cancer that has spread to the liver. It tests whether adding a new drug (sotevtamab) to standard chemotherapy (FOLFOX) before surgery can help shrink tumors and improve outcomes.
Montreal, QuebecAges 18 years+ - NCT06235125RecruitingPhase 1
Using Cytalux during lung surgery in children and teens
This study tests whether a dye called Cytalux, injected before lung surgery, can help surgeons see and remove cancer spots in children and teens with certain cancers. It may help make sure all visible cancer is removed during the operation.
Chicago, IllinoisAges 6–17 - NCT06244264Recruiting
Using your own blood during spine surgery for lung cancer
This study tests the safety and effectiveness of using your own blood (collected before surgery) during spine surgery for lung cancer that has spread to the backbone. It may help people whose spine is unstable or causing nerve problems.
Guangzhou, GuangdongAges 18–75 - NCT06244004RecruitingPhase 2
PET-guided radiation for metastatic hormone-sensitive prostate cancer
This trial tests whether using a special PET scan (FDG-PET) to find and treat only the spots where cancer has spread with targeted radiation can help men with prostate cancer that has spread but still responds to hormone therapy. It compares standard treatment alone to standard treatment plus this targeted radiation.
Chicago, IllinoisAges 18 years+ - NCT06252129Recruiting
Improving Lymph Node Removal During Lung Cancer Surgery
This trial studies a better way to remove and examine lymph nodes from lung cancer surgery specimens. It aims to improve how doctors check for cancer spread, which may help guide your treatment after surgery.
Boston, MassachusettsAges 18 years+ - NCT06264167Recruiting
Ultrasound for groin lymph nodes in vulvar cancer
This trial tests whether using ultrasound of the groin can help find cancer spread in the lymph nodes of women with early-stage vulvar cancer. The goal is to see if ultrasound can replace or reduce the need for more invasive surgery.
Brisbane, QueenslandAges 18 years+ - NCT06286631Recruiting
Predicting lymph node spread in thyroid cancer with a new scale
This trial is testing a new scale to predict if thyroid cancer has spread to nearby lymph nodes. It may help doctors decide on the best treatment for you.
Xi'an, ShaanxiAges 16–80 - NCT06287723Recruiting
Blood test for cancer DNA after liver surgery in colorectal cancer
This study uses a simple blood test (liquid biopsy) to look for tiny bits of cancer DNA after surgery for colorectal cancer that spread to the liver. It aims to see if this test can find cancer earlier than standard scans, which may help guide future treatment decisions.
MontpellierAges 18 years+ - NCT06293157Recruiting
Carbon fiber screws for spinal cancer treatment
This trial tests if carbon fiber screws are better for stabilizing the spine when cancer has spread there. It may help patients who are getting special radiation therapy (SBRT) for spinal tumors.
BydgoszczAges 18 years+ - NCT06307080Recruiting
Combined ablation and immunotherapy for pancreatic cancer with liver spread
This study tests a new treatment combining tumor destruction with heat/cold (ablation) and an immunotherapy drug (PD-1) for people whose pancreatic cancer has spread to the liver. The goal is to help the immune system fight the cancer better.
Shanghai, Shanghai MunicipalityAges 18–70 - NCT06315010RecruitingPhase 2
Repotrectinib for ROS1-positive lung cancer with brain spread
This clinical trial tests a new targeted therapy pill (repotrectinib) for people with ROS1-positive lung cancer that has spread to the brain. The pill is designed to enter the brain and attack cancer cells that other targeted treatments may not reach well.
GrazAges 18 years+ - NCT06317181Recruiting
Liver disease evaluation with AI-enhanced ultrasound
This trial tests whether a new deep-learning computer program can better detect liver disease using ultrasound data. It may help improve diagnosis without extra procedures.
DresdenAges 18 years+ - NCT06349590RecruitingPhase 1/Phase 2
Diet before colon cancer surgery to reduce recurrence
This trial tests whether a specific diet before colon cancer surgery can change the bacteria in your gut to help prevent the cancer from coming back or spreading. Patients who are eligible will follow the diet for a short time before their operation.
Chicago, IllinoisAges 18 years+
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Common questions
- Are there clinical trials for metastasis?
- Yes. Clin2 currently lists 343 recruiting metastasis studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a metastasis trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a metastasis trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.