Clinical trials
Metastatic Breast Cancer clinical trials
Below are recruiting metastatic breast cancer clinical trials, each written for real people, not researchers. We’re tracking 1,328 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT06927102Recruiting
Bringing back breast cancer patients lost to follow-up
This study looks at people with breast cancer who stopped coming to follow-up appointments. It aims to understand why they dropped out and help them re-engage with care.
Hyderabad, TelanganaAges 18 years+ - NCT06929910Recruiting
K4Care test study for metastatic cancer patients
This study tests how well the K4Care blood test can monitor treatment in people with advanced solid tumors like lung, colorectal, breast, or stomach cancer that has spread. Researchers want to see if tracking tumor DNA in the blood helps guide therapy.
Ho Chi Minh City, Hồ Chí MinhAges Any age - NCT07397585Recruiting
SBRT for Limited Metastatic Breast Cancer: A Database Study
This study looks back at medical records of people with breast cancer that has spread to only a few spots (oligometastases) who received a special type of radiation called SBRT. It aims to learn how well this treatment works and to help doctors better understand who benefits most.
Benevento, BeneventoAges 18 years+ - NCT07500012Recruiting
Ear nerve stimulation for breast cancer pain
This study tests whether gentle electrical stimulation of a nerve in your ear (called taVNS) can help reduce pain and improve symptoms for breast cancer survivors. You would need to have finished your main treatments, have ongoing pain, and be willing to provide stool samples and undergo brain scans.
Tallahassee, FloridaAges 18–79 - NCT07600957Recruiting
Polarized Light Therapy to Ease Radiation Skin Damage
This trial tests whether a special type of light therapy can reduce skin damage and irritation that happens during radiation treatment for breast cancer. If it works, it could help patients feel more comfortable during and after their radiation therapy.
Banī SuwayfAges 35–55 - NCT07612215RecruitingPhase 1/Phase 2
Elacestrant for Advanced Triple-Positive Breast Cancer
This trial tests a new drug called elacestrant for advanced breast cancer that is triple-positive (positive for three hormone receptors: ER, PR, and HER2). The drug may help slow or shrink cancer that has progressed despite previous treatments.
New York, New YorkAges 18 years+ - NCT05329532RecruitingPhase 1/Phase 2
Modi-1 cancer vaccine for several hard-to-treat cancers
This Phase 1/2 study tests a cancer vaccine called Modi-1 Moditope in people with advanced triple-negative breast cancer, head and neck cancer, ovarian/high-grade serous cancer, or kidney cancer. It aims to help the immune system better recognize and attack the cancer.
Brighton, DefaultAges 18 years+ - NCT04680260RecruitingPhase 2
Personalized follow-up after limited surgery or radiation for colon cancer
This Phase 2 study tests the best way to choose and then follow treatment when colorectal cancer has spread only to a small number of spots. You may be eligible if your doctors can remove or precisely treat the spots and there’s no sign of additional spread on scans.
Aarhus NAges 18 years+ - NCT05721976Recruiting
Grandmother–daughter lifestyle program for certain cancer survivors
This pilot study tests a supportive program for grandmothers who finished breast, endometrial, or ovarian cancer treatment and their adult daughters. It aims to encourage healthier habits, including physical activity, using phone-based support and Spanish/English materials.
Miami, FloridaAges 21 years+ - NCT05867966Recruiting
Testing a hypnosis-based program for symptom clusters in cancer
This trial studies whether a hypnosis-based approach can help reduce a selected set of troubling symptoms in people who have finished treatment for certain early-stage (non-metastatic) cancers. It aims to understand which symptom patterns improve and how well the intervention works.
LiègeAges 18 years+ - NCT06963723Recruiting
Screening for financial hardship in advanced cancer
This study screens people with advanced cancer for financial problems. It aims to see if catching these problems early can improve your care and well-being.
Phoenix, ArizonaAges 21 years+ - NCT03786796RecruitingPhase 2
Olaparib for metastatic kidney cancer with specific DNA repair gene changes
This trial tests olaparib (a pill medicine) in people with kidney cancer that has spread and specific DNA “repair” gene mutations. The goal is to see whether this targeted treatment can slow the cancer or help it respond better after prior immunotherapy or blood-vessel–blocking therapy.
Baltimore, MarylandAges 18–120 - NCT03815890RecruitingPhase 2
Pre-surgery nivolumab for certain types of breast cancer
This trial tests whether giving nivolumab before surgery (neoadjuvant treatment) can improve outcomes for people with certain resectable breast cancers. It focuses on tumor types linked to immune activity (like triple-negative and specific lab markers).
AmsterdamAges 18 years+ - NCT07330544RecruitingPhase 2
Study of entinostat with anlotinib or fulvestrant for advanced breast cancer
This trial tests adding entinostat (a drug that may help hormone therapy work better) to anlotinib or fulvestrant for people with HR-positive, HER2-negative advanced breast cancer that has worsened after prior hormone therapy and a CDK4/6 inhibitor. It aims to find a new treatment option for those who cannot use chemotherapy yet.
Zhejiang, HangzhouAges 18 years+ - NCT04865887RecruitingPhase 2
Pembrolizumab plus lenvatinib for advanced cervical cancer
This Phase 2 trial studies whether pembrolizumab and lenvatinib can improve outcomes in people with advanced cervical cancer that has grown or stopped responding to earlier treatments. It may help by boosting the immune system and slowing cancer growth.
Washington D.C., District of ColumbiaAges 18 years+ - NCT06193369Recruiting
Digital peer support for young adults with cancer
This trial connects you with a trained peer (someone who has been through cancer) who provides support and guidance online. It's for young adults who finished treatment for certain cancers in the past year.
Toronto, OntarioAges 18–40 - NCT05447988Recruiting
Breast reconstruction study using a new tissue expander
This trial studies a new device used during breast reconstruction after mastectomy, usually to stretch skin before placing a breast implant. It may help people who’ve had breast cancer and completed radiation at least a year ago by improving the reconstruction process and tracking outcomes.
RancaguaAges 18 years+ - NCT01521741Recruiting
Breast cancer lymphedema screening to detect early swelling
This trial looks at whether scheduled measurements can spot early swelling (lymphedema) in people with breast cancer. It may help find problems sooner so treatment or prevention steps can start earlier.
Boston, MassachusettsAges 18 years+ - NCT05075512RecruitingPhase 2
Anlotinib with fulvestrant for advanced, HR-positive, HER2-negative breast cancer
This trial studies whether adding anlotinib (a targeted medicine) to fulvestrant (a hormone-blocking injection) can improve outcomes for people with advanced HR-positive, HER2-negative breast cancer. It focuses on safety and effectiveness when cancer has returned or progressed after hormone treatments.
Hangzhou, ZhejiangAges 18 years+ - NCT04504747Recruiting
Real-time breast cancer testing during chemotherapy
This trial studies real-time molecular testing in people with breast cancer who are receiving chemotherapy before surgery. The goal is to learn how the cancer changes during treatment and whether this helps guide care around surgery and radiation.
Marseille, MarseilleAges 18 years+ - NCT04282031RecruitingPhase 1/Phase 2
BPI-1178 for advanced breast cancer or solid tumors
This early-phase study tests BPI-1178 in people with advanced (stage 4 or hard-to-treat) solid tumors, including HR+/HER2- breast cancer. It looks at how well the treatment works and how safe it is, especially after standard treatments have stopped working or aren’t an option.
Shanghai, Shanghai MunicipalityAges 18 years+ - NCT06454864Recruiting
Exercise and Diet for Breast Cancer Survivors
This study tests whether a 6-month program combining weekly supervised exercise and dietary advice can improve health in breast cancer survivors who have completed initial treatments. It aims to help with weight, heart health, and overall well-being.
Toronto, OntarioAges Any age - NCT06418594RecruitingPhase 2
Drug combo for HER2-negative breast cancer brain metastasis
This trial tests a combination of two drugs (adebrelimab and apatinib) plus chemotherapy for women with HER2-negative breast cancer that has spread to the brain. It aims to see if this treatment can help shrink or control brain tumors.
Beijing, Beijing MunicipalityAges 18 years+ - NCT06856200Recruiting
Sirolimus plus palbociclib and fulvestrant for advanced breast cancer
This trial tests a new combination of three drugs (sirolimus, palbociclib, and fulvestrant) for people with a certain type of advanced breast cancer that is hormone receptor-positive and HER2-negative. The goal is to see if adding sirolimus can help control the cancer when standard hormone therapy is no longer working.
ShanghaiAges 18 years+
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Common questions
- Are there clinical trials for metastatic breast cancer?
- Yes. Clin2 currently lists 1,328 recruiting metastatic breast cancer studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a metastatic breast cancer trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a metastatic breast cancer trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
- Breast Cancer Early Stage Breast Cancer (Stage 1-3)
- Breast Cancer (Triple Negative Breast Cancer (TNBC))
- Locally Advanced or Metastatic Breast Cancer
- Metastatic Triple-negative Breast Cancer
- HER2-positive Metastatic Breast Cancer
- Advanced/Metastatic Breast Cancer
- Non-metastatic Breast Cancer
- Advanced or Metastatic Breast Cancer
Beyond the search
We also like to point to nonprofits doing real good in this area. We aren’t affiliated with them — we just admire the work.
- Stand Up To CancerPeople facing cancer across many types, through the research that leads to better treatments.
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.