Clinical trials
Methylprednisolone clinical trials
Below are recruiting methylprednisolone clinical trials, each written for real people, not researchers. We’re tracking 91 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT03924791Recruiting
Epidural injection trial for acute sciatica pain
This study tests whether a specific back/nerve pain injection (an epidural injection) can help people with acute sciatica. You may qualify if your sciatica started a few weeks ago and your leg pain is still quite severe.
HaarlemAges 18 years+ - NCT03952637RecruitingPhase 1/Phase 2
Gene therapy for GM1 disease with IV delivery
This early-stage study tests an IV gene therapy that delivers a working copy of an enzyme gene to help the body make beta-galactosidase in GM1 gangliosidosis. It may help slow or improve disease symptoms and looks closely at safety and how well the treatment works.
Bethesda, MarylandAges 6 months–12 years - NCT04192656RecruitingPhase 4
PAP treatment for sudden hearing loss with sleep apnea
This trial tests whether using PAP (a breathing device for sleep apnea) can improve sudden hearing loss that happens alongside obstructive sleep apnea. It may help by reducing stress on the body during sleep and supporting hearing recovery.
Beijing, Beijing MunicipalityAges 18–70 - NCT04216524RecruitingPhase 2
Venetoclax plus chemotherapy for blastic dendritic cell cancer
This Phase 2 trial tests venetoclax combined with chemotherapy to treat blastic plasmacytoid dendritic cell neoplasm (BPDCN). It may help shrink BPDCN and control the disease, whether you’re newly diagnosed or the cancer has come back.
Houston, TexasAges 18 years+ - NCT04224558RecruitingPhase 1/Phase 2
Stem cell transplant for hard-to-control Crohn’s disease
This early-phase study tests whether a stem cell transplant can improve Crohn’s disease in teens and young adults whose disease is active and not responding to standard medicines. It may help some people who are not doing well despite several prior treatments, but it also involves intensive study procedures and safety checks.
Los Angeles, CaliforniaAges 13–28 - NCT04685772Recruiting
Medrol Dose Pack for new concussion headache relief
This trial tests whether a Medrol “dose pack” (a short course of steroid medicine taken by mouth) can reduce acute headache pain after a concussion. It may help people whose concussion headaches are frequent and severe soon after injury.
Manhasset, New YorkAges 18 years+ - NCT04787744RecruitingPhase 2/Phase 3
Test standard prostate cancer treatment with or without targeted spot radiation
This study tests whether adding targeted local treatment (like radiation to a few spots seen on scans) improves outcomes for some people with limited (oligometastatic) prostate cancer. It compares standard systemic therapy alone versus standard therapy plus PET-scan–guided spot treatment.
Long Beach, CaliforniaAges 18 years+ - NCT04873583RecruitingPhase 3
High-dose steroids for children after a one-sided stroke
This trial tests whether high-dose steroids given soon after a stroke can improve outcomes for children. It is aimed at children whose stroke is caused by a one-sided blood-vessel problem seen on brain scans.
Randwick, New South WalesAges 6 months–17 years - NCT06809998RecruitingPhase 1/Phase 2
Steroid injection in non-surgical knee before knee replacement
This study tests whether a single steroid injection in the healthy knee (the one not being replaced) can reduce pain and improve recovery after total knee replacement. It may help people who have arthritis in both knees but are only having one replaced now.
Toronto, OntarioAges 18 years+ - NCT04936854RecruitingPhase 2
Sirolimus or steroid drops for active Graves eye disease
This Phase 2 study compares sirolimus versus corticosteroids to treat active thyroid eye disease. It aims to see which treatment works better to calm eye inflammation and improve symptoms, without needing urgent eye surgery.
Bergen, HordalandAges 18–80 - NCT05150704RecruitingPhase 3
Steroid treatment for suspected acute myocarditis in hospital
This study tests whether steroid medicine helps people hospitalized with suspected acute myocarditis (inflammation of the heart). Participants are randomly assigned to receive steroids or a placebo, and the trial looks at outcomes after the acute episode starts.
San Diego, CaliforniaAges 18–69 - NCT05324748RecruitingPhase 3
Repeated nerve-block shots for chronic cluster headache
This Phase 3 trial tests whether repeated injections can reduce attacks of chronic cluster headache. It may help people who have frequent, consistent attacks and can track them closely during the study.
LeidenAges 18–70 - NCT05842681Recruiting
Azithromycin for early worsening of idiopathic pulmonary fibrosis
This trial studies whether adding azithromycin to standard care can help people whose idiopathic pulmonary fibrosis is starting to flare up (worsen) in the early stages. It’s mainly for adults who are not very sick and cannot require intensive breathing support.
AsyutAges 18–80 - NCT05925309Recruiting
Oral antibiotics to prevent bile duct inflammation after Kasai surgery
This trial studies whether giving oral antibiotics before symptoms start can lower the chance of cholangitis (bile duct infection/inflammation) after Kasai portoenterostomy. It may help protect your child’s bile flow and reduce painful or serious infections after surgery.
Shanghai, Shanghai MunicipalityAges 2 weeks–3 months - NCT05947669RecruitingPhase 3
Infliximab for diarrhea or colitis from immune cancer therapy
This trial studies whether infliximab can treat stomach inflammation in the colon (colitis) or frequent diarrhea caused by immune checkpoint cancer drugs. It aims to improve symptoms safely for adults with certain solid cancers.
AalborgAges 18 years+ - NCT06119490RecruitingEarly Phase 1
Methylprednisolone and JAK inhibitor for severe skin reaction
This trial tests a combination of a steroid (methylprednisolone) and a JAK inhibitor to treat toxic epidermal necrolysis, a severe skin reaction. The goal is to see if adding the JAK inhibitor helps improve outcomes and safety.
Fuzhou, FujianAges 18–70 - NCT06209606RecruitingEarly Phase 1
Blood test study for multiple myeloma progression
This study is testing whether a blood test that measures a protein called BCMA can help doctors know if your multiple myeloma is getting worse. You may be able to join if your myeloma has come back or not responded to at least two prior treatments, and you have not taken the drug Ruxolitinib before.
West Hollywood, CaliforniaAges 18 years+ - NCT05097976RecruitingPhase 4
Medrol tablets to reduce pain after knee replacement
This trial tests whether a short course of Medrol (methylprednisolone) can improve recovery after outpatient total knee replacement done for osteoarthritis. You would be randomly assigned to receive Medrol or a comparison treatment.
Oak Brook, IllinoisAges 18 years+ - NCT06496997RecruitingPhase 2/Phase 3
Steroid treatment for acute lung failure (ARDS) trial
This study tests if adding a type of steroid (glucocorticoid) to standard treatment helps people on a breathing machine recover from severe lung failure (ARDS). It compares different doses to see which works best.
Al FayyumAges Any age - NCT06670521RecruitingPhase 2
Steroids for swallowing problems after breathing tube removal
This trial tests a steroid medication (corticosteroids) to reduce swelling in the voice box after a breathing tube is taken out. It may help improve swallowing and reduce the risk of food or drink going into the lungs.
Aurora, ColoradoAges 18 years+ - NCT06676579RecruitingPhase 2
Avacopan for active IgA kidney disease with crescents
This trial tests if avacopan, a targeted anti-inflammatory drug, can safely treat a severe form of IgA nephropathy (IgAN) where small crescents form in the kidney filters. It may help reduce protein leakage and preserve kidney function.
Jacksonville, FloridaAges 18 years+ - NCT06730308RecruitingPhase 2
Steroids with chemoradiation for thymoma that can't be removed
This trial tests if adding a steroid (methylprednisolone) to standard chemotherapy and radiation helps people with thymoma that cannot be fully removed by surgery or has come back. The goal is to see if this combination works better at controlling the disease.
Guanzhou, GuangdongAges 18–75 - NCT06763848Recruiting
Blood filtering for NMOSD attacks
This trial tests a blood filtering procedure called Protein A immunoadsorption for people having an acute episode of neuromyelitis optica spectrum disorder (NMOSD). It may help remove harmful antibodies from your blood and reduce symptoms.
Guangzhou, GuangdongAges 18–65 - NCT06841705RecruitingPhase 2
Early vedolizumab as first treatment for colitis from immunotherapy
This trial tests if giving vedolizumab early can help control severe diarrhea and colon inflammation caused by immunotherapy (a type of cancer treatment). It may offer a new option for people who develop these side effects.
Boston, MassachusettsAges 18 years+
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Common questions
- Are there clinical trials for methylprednisolone?
- Yes. Clin2 currently lists 91 recruiting methylprednisolone studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a methylprednisolone trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a methylprednisolone trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.