Clinical trials
Microbiome clinical trials
Below are recruiting microbiome clinical trials, each written for real people, not researchers. We’re tracking 346 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT03589183Recruiting
Gut microbiome study for ulcerative colitis and Crohn disease
This study looks at how changes in gut bacteria (the microbiome) relate to inflammatory bowel disease, including ulcerative colitis and Crohn disease. It may help researchers understand what might improve symptoms or disease control.
SeoulAges Any age - NCT05326334Recruiting
Study gut microbiome in new glioblastoma patients
This trial studies how changes in gut bacteria (gut microbiome) relate to outcomes in people with newly diagnosed glioblastoma receiving standard chemo-radiation. It may help doctors learn which gut-bacteria patterns go along with better or worse results during treatment.
Ottawa, OntarioAges 18 years+ - NCT05916755Recruiting
Testing tumor clues that predict response to immunotherapy
This study looks for “biomarkers,” or tumor clues, that may help predict who benefits from checkpoint inhibitor immunotherapy in triple-negative breast cancer. It may help doctors choose the right treatment approach in the future, especially when chemotherapy is planned.
BarcelonaAges 18 years+ - NCT04529889Recruiting
Study of gestational diabetes during pregnancy and child outcomes
This study follows pregnant people with gestational diabetes to see how it affects mothers and babies over time. The team may use this information to better understand risks and care for both you and your child.
Guangzhou, GuangdongAges Any age - NCT06136845Recruiting
Esophageal cancer microbiome and leak after surgery
This study looks at bacteria in esophageal cancer tumors and whether certain bacteria are linked to leaks that can happen after surgery to remove the esophagus. It may help doctors understand how to prevent these leaks in the future.
HaifaAges 18–85 - NCT06076083Recruiting
Microbiome study in Korean patients with ankylosing spondylitis
This study looks at the bacteria living in your body (the microbiome) in people with ankylosing spondylitis and their close family members. Researchers hope to better understand how these bacteria relate to the disease, which may lead to better treatments in the future.
Seoul, Kyungheedae-ro 23Ages 19–60 - NCT05061329Recruiting
Learn how the nose’s microbes relate to health and disease
This study explores the tiny living organisms (microbes) in your nose and how they may be linked to health problems. It may help researchers better understand disease triggers and potential new prevention or treatment ideas.
Holstebro, Central JutlandAges 18 years+ - NCT05024188Recruiting
Gut bacteria and exercise performance study
This study looks at how the bacteria in your gut might affect your physical fitness and exercise ability. You would need to be a regular exerciser and take some antibiotics as part of the study.
RehovotAges 20–55 - NCT06203249Recruiting
Exploring lung health and immune system in a rare muscle disease
This trial looks at how the immune system and tiny organisms in the lungs may affect a rare condition called anti-MDA5 positive dermatomyositis, which can cause serious lung disease. It may help doctors understand why some patients get worse quickly and how to better treat them.
Beijing, Beijing MunicipalityAges 18–100 - NCT07868432Enrolling by invitation
How artificial sweeteners affect blood sugar in prediabetes
This study looks at how non-nutritive sweeteners (like aspartame or sucralose) affect blood sugar levels in people with prediabetes. It aims to see if these sweeteners change gut bacteria and, in turn, blood sugar control.
Boston, MassachusettsAges 35 years+ - NCT03962920Recruiting
Personalized care for urologic cancer based on gut and urine bacteria
This study looks at how your body’s bacteria (microbiome in and around the urinary/genital area) may help guide personalized treatment for localized urologic cancers. The goal is to see whether tailoring treatment to your bacteria could improve outcomes.
RoskildeAges 40–70 - NCT05670262Recruiting
Study vitamin D and gut bacteria in childhood allergies
This study looks at how gut bacteria (microbiome) and vitamin D levels in newborns may influence whether children develop allergies. It starts with newborn babies and aims to better understand what early factors could predict allergic diseases.
TaichungAges birth–1 year - NCT06260579Recruiting
Home exercise program after kidney transplant
This study tests whether a home exercise program, especially with higher intensity, can help people recover better after a kidney transplant. You would exercise on a stationary bike at home, with guidance from a team.
GhentAges 18 years+ - NCT02526901Recruiting
Pregnancy cohort study for women in Guangzhou
This study follows pregnant women from early pregnancy to learn about pregnancy and child health. You may be asked to share health information so researchers can better understand outcomes for babies born in Guangzhou.
Guangzhou, GuangdongAges Any age - NCT03331133Recruiting
Study of twins born in Guangzhou
This study focuses on twins who were born at Guangzhou Women and Children’s Medical Center. It aims to use pregnancy and baseline information to learn about twin outcomes and care, and it may help local doctors improve guidance for families in Guangzhou.
Guangzhou, GuangdongAges Up to 18 years - NCT03668327Recruiting
Study of babies born early in Guangzhou
This study follows babies who were born early (before 37 weeks) to learn more about health outcomes over time. It may help doctors better understand and support families after an early birth.
GuangzhouAges Up to 18 years - NCT03650829Recruiting
IVF baby study for pregnancies in Guangzhou
This study looks at babies born from IVF (assisted reproductive technology) pregnancies. It may help the hospital better understand outcomes for families who plan to deliver there and stay in Guangzhou for years.
Guangzhou, GuangdongAges Up to 18 years - NCT06331988Recruiting
Study of colon cancer, bacteria, and the immune system
This study looks at how bacteria in your gut, your immune system, and colon cancer interact. It aims to understand these connections to improve future treatments.
MilanAges 18–75 - NCT03373721Recruiting
Compare gut microbes in preterm vs full-term babies
This study looks at differences in the gut bacteria of babies born early (preterm) compared with babies born full-term. It may help researchers understand how early birth affects early health and gut development.
ShanghaiAges 1 day–4 months - NCT04680377Recruiting
Using gut microbes to predict durvalumab side effects in lung cancer
This study looks at the microbiome (the tiny organisms in your gut) to try to predict who will get side effects from durvalumab after chemoradiation. If you join, your care team will use your microbiome results to help understand toxicity risk and improve future treatment planning.
Kansas City, KansasAges 18 years+ - NCT06423976Recruiting
Studying microbes in prostate cancer tumors
This trial collects tumor samples from men with prostate cancer to study the bacteria and other microbes inside the tumor. It aims to learn how these microbes might affect the cancer and treatment.
Sutton, SurreyAges 18 years+ - NCT04117321Recruiting
Study of mother-to-baby gut germs and baby health
This study looks at how germs in a mother can be passed to her baby and whether that affects the baby’s health. If you join, your baby (and the other parent or legal guardian) may be asked to share consent so researchers can follow the pregnancy and early life.
Hong Kong, Hong KongAges Any age - NCT07844668Enrolling by invitation
Gut health, diet, and quality of life in CVID
This study looks at the gut microbiome (the bacteria in your digestive system), diet, and quality of life in people with CVID, a condition that affects the immune system. It compares those who receive immunoglobulin therapy (antibody treatment) with those who do not, to see if there are differences that might help improve care.
Ninove, BelgieAges 18 years+ - NCT07834138Recruiting
Study of facial skin bacteria in acne patients treated with isotretinoin
This study looks at how the bacteria on your face change when you take a medicine called isotretinoin for acne. It might help doctors understand why the medicine works and how to improve acne treatment.
Can ThoAges 16–35
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Common questions
- Are there clinical trials for microbiome?
- Yes. Clin2 currently lists 346 recruiting microbiome studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a microbiome trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a microbiome trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.