Clinical trials
Microbiome clinical trials
Below are recruiting microbiome clinical trials, each written for real people, not researchers. We’re tracking 346 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT07821060Enrolling by invitation
Diet and meal timing for attention deficit hyperactivity disorder
This study looks at whether changing when you eat and improving your gut health (microbiome) can help manage attention deficit hyperactivity disorder (ADHD). It compares different diet and eating schedules to see if they improve ADHD symptoms.
Paterna, ValenciaAges 18–65 - NCT07824921Enrolling by invitation
Oral microbiome in aorta aneurysm and carotid atherosclerosis
This study looks at how bacteria in your mouth might be linked to the health of your blood vessels. It may help doctors understand why some people get aneurysms or blocked arteries, and could lead to better ways to prevent or treat these conditions.
BudapestAges 18–110 - NCT06492200Recruiting
High-Fiber Diet for Rheumatoid Arthritis
This study tests whether eating more high-fiber foods can improve rheumatoid arthritis symptoms by changing the bacteria in your gut. You would follow a special diet and have your disease activity monitored.
WürzburgAges 18–99 - NCT07816809Recruiting
Phage therapy for gut discomfort
This trial tests whether taking special capsules with friendly viruses (phages) can help reduce stomach pain, bloating, constipation, or diarrhea by balancing the bacteria in your gut.
Fort Collins, ColoradoAges 18–75 - NCT06205862RecruitingPhase 2
Fecal transplant for preventing colon polyp return
This study tests whether taking capsules of healthy bacteria (fecal microbiota transplant) can help prevent colon polyps from coming back after they have been removed. It might be an option for people who have had an adenoma polyp removed and want to reduce the chance of recurrence.
Guangzhou, GuangdongAges 18–75 - NCT06505330Recruiting
Probiotics for kids with cleft palate
This study looks at whether giving probiotics (helpful bacteria) to children with cleft palate can improve the bacteria in their airways and possibly prevent infections. Researchers want to see if this simple treatment helps keep kids healthier.
Edegem, AntwerpAges 6 months–2 years - NCT07807228Recruiting
Skin microbiome changes with lebrikizumab for eczema
This study looks at how lebrikizumab, a biologic medicine for atopic dermatitis (eczema), affects the skin's microbiome (the natural community of microorganisms on your skin). It aims to see if changes in the skin's microbiome are linked to treatment response.
CopenhagenAges 18 years+ - NCT05328999Recruiting
Study links fertility, pregnancy loss, and gut microbes
This trial studies how gut bacteria (your “microbiome”) may relate to infertility, recurrent pregnancy loss, and time to pregnancy. It may help researchers understand what could be changed to improve fertility outcomes.
Graz, StyriaAges 18–50 - NCT07792980Recruiting
Study of gut bacteria in colon cancer surgery
This study uses AI to analyze gut bacteria (microbiome) in people with colon cancer before and after surgery, to see how it relates to the effectiveness of a treatment called MPRO. It may help improve recovery and outcomes.
Seoul, SeoulAges 20–80 - NCT07794956RecruitingEarly Phase 1
Memory study for older adults with a care partner
This study tests a dietary product, called LpD3.5, to see if it can help older adults with mild memory problems. You and a care partner would take part together.
Tampa, FloridaAges 60 years+ - NCT07799402Recruiting
How gut and brain health change with age
This study looks at how the bacteria in your gut are linked to brain health as you age. It includes people with normal memory, mild memory problems, or Alzheimer's disease, and aims to find ways to keep brains healthy as we get older.
Tampa, FloridaAges 18 years+ - NCT07791849Recruiting
Comparing two stomach protectors after stem cell transplant
This study compares two medications, GMPA and PPI, that protect the stomach during a stem cell transplant. It aims to see which one is better at preventing stomach problems and reducing the risk of a complication called graft-versus-host disease (aGVHD), where donor cells attack the patient's body.
HangzhouAges 12–70 - NCT07779265Recruiting
Probiotic supplement for gut health in healthy adults
This trial tests a daily probiotic supplement's effect on digestion, immune health, and overall well-being. If you're a healthy adult, you may help discover if this product can make you feel better day-to-day.
TrierAges 18–65 - NCT07782593Recruiting
Snack bars for appetite and gut health in UK adults
This study is testing how certain snack bars affect appetite, fullness, and gut health in adults. Participants will eat the snack bars regularly for a period and have their responses measured. To join, you need to live in the UK, snack regularly, and have a low fiber diet.
LondonAges 35–65 - NCT07776418Recruiting
How different snacks affect appetite after eating
This study tests how different snack bars affect your hunger, fullness, and digestion in the hours after eating. You may be eligible if you eat snacks regularly and are interested in how your body responds to food.
LondonAges 35–65 - NCT07767981Recruiting
Gut bacteria and side effects of precise radiation therapy
This study looks at how the bacteria in your gut might affect side effects from a precise type of radiation therapy called stereotactic radiosurgery. By collecting samples, researchers hope to find ways to reduce side effects in the future.
Chicago, IllinoisAges 18 years+ - NCT06074250RecruitingPhase 2/Phase 3
Pregnancy, mood, and gut health study
This study tests whether a nutritional supplement can help prevent depression and anxiety during and after pregnancy. It looks at how the mother's gut bacteria may influence mood.
Toronto, OntarioAges 18–43 - NCT06584565Recruiting
Predicting stroke recovery and risk using blood and stool tests
This study uses advanced analysis of your blood and stool samples to better predict how you will recover from a stroke and whether it might happen again. It aims to help doctors personalize your care after a stroke.
Guangzhou, GuangdongAges 18–75 - NCT06051201Recruiting
ReceptIVFity test for IVF success prediction
This trial studies a vaginal swab test called ReceptIVFity that looks at the bacteria in your vagina to see if it can help predict how well IVF will work. You can join if you're about to start your first IVF cycle, are not on hormonal birth control or antibiotics, and your IVF is not for emergency reasons.
RotterdamAges 18–42 - NCT07750249Enrolling by invitationEarly Phase 1
Short-chain fatty acids for IgA nephropathy
This trial tests whether a daily supplement of short-chain fatty acids (SCFAs) can slow down kidney damage in people with IgA nephropathy. SCFAs are substances made by gut bacteria that may help reduce inflammation and protect the kidneys.
MartinAges 18 years+ - NCT07724522Recruiting
Prebiotic Fiber for Irregular Periods in Women
This study tests whether taking a prebiotic fiber (inulin) can help women who are in the later years of their reproductive life (before menopause) and have irregular periods. You may be eligible if you are overweight, have irregular cycles, sit a lot, and do not exercise much.
Washington D.C., District of ColumbiaAges 40–55 - NCT06262035Recruiting
Gum and implant disease tissue profile study
This study looks at the genetic and bacterial profiles in gum disease and implant infections. It might help find new ways to diagnose or treat these conditions.
StockholmAges 18 years+ - NCT05462496RecruitingPhase 2
Pembrolizumab plus gut microbiome changes after pancreatic chemo
This Phase 2 study tests whether changing the gut microbiome (the gut’s helpful bacteria) and giving pembrolizumab after chemotherapy can improve outcomes for people with operable pancreatic cancer. It aims to see if this approach can boost the immune system after standard treatment and help reduce cancer returning.
New York, New YorkAges 19 years+ - NCT05931718Recruiting
Track diagnosis and treatment in autoimmune blood count disorders
This study follows adults with autoimmune blood problems like autoimmune hemolytic anemia, immune thrombocytopenia, and autoimmune/neutropenia to see how diagnosis and care work over time. You may be asked to complete follow-up visits for up to 3 years.
MilanAges 18 years+
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Common questions
- Are there clinical trials for microbiome?
- Yes. Clin2 currently lists 346 recruiting microbiome studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a microbiome trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a microbiome trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.