Clinical trials
Microbiota clinical trials
Below are recruiting microbiota clinical trials, each written for real people, not researchers. We’re tracking 376 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT06724536Recruiting
Study of gut bacteria and TKIs in chronic myeloid leukemia
This trial looks at how gut bacteria affect the way chronic myeloid leukemia (CML) patients respond to tyrosine kinase inhibitor (TKI) medications. It may help doctors understand why some people have better outcomes than others.
TorinoAges 18 years+ - NCT05323357Recruiting
Study using gut samples to understand germs and your immune system
This study collects gut tissue (biopsies) and blood to learn how gut germs (microbes) and the immune system interact. It may help researchers understand why gut infections or immune problems happen and improve future treatments.
BernAges 18–80 - NCT04919265Recruiting
Mother and baby health study from early pregnancy
This study follows pregnant people and their babies from the first few months of pregnancy through at least one year after birth. It aims to learn how health and development turn out, especially for mothers who can keep coming to the same clinic for follow-up.
Kajang, SelangorAges 18–45 - NCT07567794Recruiting
Gut-Brain Connection Study in Parkinson's Disease
This research examines how the gut and brain are connected in Parkinson's disease and aims to better understand the disease. You'd participate in visits and tests over three years, including some involving your digestive system.
Stanford, CaliforniaAges 21–80 - NCT07553936Recruiting
Alternative Proteins in Mediterranean Food Supply Chains
This study tests new plant-based and alternative protein foods (like those from legumes, insects, and algae) to see if they're safe, healthy, and practical for everyday use. You'll help researchers understand how these sustainable protein options can work in Mediterranean diets.
Bologna, BOAges 18–65 - NCT05587036RecruitingPhase 2/Phase 3
Rifaximin study to see how gut bacteria affect mood
This trial tests whether a gut-targeting antibiotic called rifaximin changes the gut microbiome (gut bacteria) and affects emotion. It is looking for healthy men so any mood or gut changes can be more clearly linked to the study treatment.
LeuvenAges 18–50 - NCT06690593Recruiting
Gut Microbiome Study for Healthy Adults Age 45+
This study compares the gut bacteria of healthy adults (age 45+) with those who have a blood condition called monoclonal gammopathy. The goal is to see if gut bacteria patterns differ between the two groups.
Guanzhou, GuangdongAges 45 years+ - NCT07535619Recruiting
Microbiota study in children with and without overactive bladder
This research study compares the bacteria in urine, around the genital area, and in stool between children with overactive bladder (frequent urgent need to urinate) and healthy children. The goal is to understand if differences in these bacteria might explain why some children develop overactive bladder.
AalborgAges 5–17 - NCT06759324Recruiting
Kombucha for weight: live vs. pasteurized effects
This study compares the effects of live kombucha versus pasteurized kombucha on gut health, metabolism, and liver function in people who are overweight or obese. Participants will drink kombucha daily for a set period to see if it improves their health.
Castelo Branco, Castelo Branco DistrictAges 18–60 - NCT06758817Recruiting
Nutrition, gut health, and rheumatoid arthritis study
This trial tests if a specific diet can improve your rheumatoid arthritis symptoms by affecting your gut bacteria. You may be eligible if you have active RA and are willing to follow a special meal plan for several weeks.
Lisbon, PortugalAges 18 years+ - NCT07509450Recruiting
Fecal transplant study for CAR-T and stem cell transplant patients
This pilot study tests whether giving a fecal microbiota transplant before standard CAR-T therapy (for B-cell lymphoma) or reduced-intensity stem cell transplant (for AML or high-risk MDS) can improve treatment outcomes. It aims to see if restoring gut bacteria helps reduce complications.
Toronto, OntarioAges 18 years+ - NCT07499414Recruiting
Bile acid supplement for gut health in adults
This study tests whether a bile acid supplement called 7-keto lithocholic acid can positively affect your gut bacteria and reduce disease risks. Healthy adults aged 18-65 are needed.
ReadingAges 18–65 - NCT07497711RecruitingPhase 2/Phase 3
Virtual treatment for menstrual cramps
This study tests a virtual (app-based) approach to help manage menstrual cramps. It is for people with regular periods who have moderate to severe cramp pain and want to try a non-medication option.
SingaporeAges 16–35 - NCT07485296RecruitingPhase 2
Postbiotics with pembrolizumab for advanced head and neck cancer
This trial tests whether adding postbiotics (beneficial bacteria byproducts) to the standard immunotherapy drug pembrolizumab can improve your immune system's response against advanced or metastatic head and neck squamous cell carcinoma.
Rozzano, MilanoAges 18 years+ - NCT07481422RecruitingPhase 1/Phase 2
Fecal transplant capsules for irritable bowel syndrome
This trial tests whether taking capsules containing freeze-dried healthy donor stool can improve symptoms of irritable bowel syndrome (IBS) that haven't gotten better with usual treatments. It aims to see if this approach is safe and helpful for people with moderate to severe IBS.
RijekaAges 18–65 - NCT07476703Recruiting
Extended study on the SCAPIS Stockholm reexamined group
This trial studies data and samples from people already taking part in the main SCAPIS reexamination study in Stockholm. It looks for new findings to help understand heart and lung health.
StockholmAges 56–74 - NCT06784557RecruitingPhase 4
Study of ezetimibe's effect on gut bacteria
This trial tests whether ezetimibe, a cholesterol-lowering drug, changes the bacteria in your gut. It may help people with heart disease or high cholesterol who are already on a statin.
SeoulAges 19–80 - NCT07464392Recruiting
Fecal transplant to prevent infections in severe pancreatitis
This trial tests whether a fecal microbiota transplant (FMT) can help prevent infections in people with moderately severe or severe acute pancreatitis. You may qualify if you are between 18 and 75, have had pancreatitis for 15 to 21 days, and already have a feeding tube in place.
Fuzhou, FujianAges 18–75 - NCT07453823Recruiting
Synbiotic for gut health in overweight adults
This trial tests a combination supplement (a synbiotic) to see if it can improve gut function and gut bacteria in middle-aged and older adults who are overweight and have constipation. If eligible, you take the supplement daily and report how your digestion feels.
Cork, BlackpoolAges 50–70 - NCT07460856Recruiting
Can Cranberries Improve Your Gut and Metabolic Health?
This study tests if eating cranberries can improve your gut health and metabolism. It’s for people who are overweight and have early signs of metabolic problems, like high blood sugar or high triglycerides.
Québec, QuebecAges 25–70 - NCT07450443RecruitingPhase 2/Phase 3
Gut health and autism: a study on the gut barrier and bacteria
This trial is looking at the connection between the gut and autism. It tests whether certain gut bacteria and the gut's protective barrier are different in children with autism and gastrointestinal issues. This could help find new ways to improve symptoms.
Milan, MIAges 3–8 - NCT07450872Recruiting
Gut health and symptoms in childhood cancer survivors
This study looks at how cancer survivors' symptoms (like pain, fatigue, or mood) are connected to the bacteria living in their gut. It aims to understand why some children have different symptom patterns after treatment, which could help doctors provide better care.
Hangzhou, ZhejiangAges 8–18 - NCT07440147Recruiting
Akkermansia and Berberine for night shift workers' insulin sensitivity
This trial tests whether taking a probiotic called Akkermansia muciniphila and a natural plant compound called berberine can improve how your body uses insulin. If you work night shifts regularly, this study may help you find a way to support your metabolic health.
Graz, StyriaAges 21 years+ - NCT07443280Recruiting
Gut health supplement study for dialysis patients
This trial tests whether a special blend of probiotics and prebiotics (called a synbiotic) can improve gut health and reduce harmful waste products in the blood for people on hemodialysis.
Taichung, Wuqi DistrictAges 18 years+
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Common questions
- Are there clinical trials for microbiota?
- Yes. Clin2 currently lists 376 recruiting microbiota studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a microbiota trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a microbiota trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.