Clinical trials
Mild Cognitive Disorder clinical trials
Below are recruiting mild cognitive disorder clinical trials, each written for real people, not researchers. We’re tracking 312 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT07876570Recruiting
Predicting memory decline with brain and blood tests
This study follows older adults with normal memory, mild memory problems, or dementia over a year to see if brain scans and blood tests can predict who will get worse. It may help find early warning signs of Alzheimer's and other dementias.
Beijing, Beijing MunicipalityAges 50 years+ - NCT07691918Enrolling by invitation
Brain stimulation for mild memory loss
This trial tests if a non-invasive brain stimulation technique can help people with mild memory problems. It uses a special cap to gently stimulate the brain and aims to improve thinking and memory.
Roanoke, VirginiaAges 55–80 - NCT06948149Recruiting
Creatine and strength training for memory decline in older adults
This study tests whether combining a daily creatine supplement with a 26-week resistance training program can improve memory and thinking in older adults who have mild cognitive impairment. If you qualify, you'll get free supervision and supplements while contributing to research that could help many people.
London, OntarioAges 60 years+ - NCT07650318Recruiting
Virtual reality brain training for diabetes patients with memory issues
This trial tests whether virtual reality brain training can help protect thinking and memory in people with type 2 diabetes who have mild memory problems. If you have type 2 diabetes and notice some mental decline, this study may help you find ways to keep your mind sharp.
Nanjing, JiangsuAges 45–80 - NCT07763392Recruiting
Normal cognitive test scores for adults
This study is testing a voice-controlled digital platform to measure normal memory and thinking abilities in healthy adults. By participating, you would help create a baseline of normal scores that doctors can use to compare against when assessing people with thinking problems.
Carlsbad, CaliforniaAges 18–100 - NCT05929703Recruiting
Caring for hospitalized older adults
This study tests a new approach to caring for older adults in the hospital to prevent confusion (delirium). It involves having a family member or care partner stay with the patient during the hospital stay.
Orange, CaliforniaAges 70 years+ - NCT04171323Recruiting
Active mind training to improve thinking and delay dementia
This study tests an “active mind” computer-based program to help improve thinking skills and possibly slow the process toward dementia. You may be randomly assigned to different program options to see which approach works best for your goals.
San Francisco, CaliforniaAges 55–89 - NCT07652775Recruiting
Brain stimulation and exercise for memory and mood
This study tests whether combining rTMS (a non‑invasive brain stimulation) with aerobic exercise can improve memory, thinking, and mood in older adults who have mild memory problems and depression. It may offer a safe, drug‑free way to help both brain health and emotional well‑being.
Taipei, Taipei CityAges 65–90 - NCT06668610Recruiting
Brain stimulation study for mild memory problems
This study tests a non-invasive brain stimulation technique (tDCS) combined with brain wave recording (EEG) to see if it can improve memory and thinking in people with mild cognitive impairment or early dementia.
Caserta, ItalyAges 55–85 - NCT03665831Recruiting
Deep TMS for depression and memory problems in older adults
This study tests a type of brain stimulation called Deep TMS to help reduce depression and improve or stabilize memory-related symptoms in older adults with Alzheimer’s disease. It’s mainly for people whose depression did not improve or could not be tolerated with antidepressant medicine.
Toronto, OntarioAges 60 years+ - NCT07287410Recruiting
Assessing thinking and daily life in dementia and MCI
This study looks at how dementia or mild cognitive impairment affects thinking, daily living, and mood. The goal is to better understand these conditions by doing careful assessments.
Messina, MEAges 50–86 - NCT05888961Recruiting
Study of taste changes in people with memory problems
This study tracks how taste perception works in people with different stages of memory and thinking problems, including mild to moderate Alzheimer-type conditions. It uses non-painful taste testing and brain-wave measurements to understand changes over time and may help improve how these conditions are assessed.
DijonAges 18 years+ - NCT05762796Recruiting
Brain scan and stimulation study for kids with mild concussion
This study tests whether a brain “stimulation” approach, paired with brain imaging (MRI), can help children who still have symptoms after a mild concussion. There is also a comparison group of children without concussion history.
Buffalo, New YorkAges 10–15 - NCT05549102Recruiting
CBT therapy study for anxiety and brain circuit changes
This trial studies whether a specific form of talk therapy (CBT) changes brain activity in people with moderate anxiety. It may help your care team understand what works best and how brain “circuits” respond to treatment.
LondonAges 18–64 - NCT06983119Recruiting
Finding early signs of memory loss in Pavia
This study looks for early thinking and memory changes in people 50 and older who haven't been diagnosed with cognitive decline. You'll complete a quick assessment to see if further checkups might help.
Pavia, PaviaAges 18 years+ - NCT07038798Recruiting
Deep rTMS for mild memory problems in older adults
This trial is testing whether a non-invasive brain stimulation technique called deep rTMS can help older adults with mild memory or thinking problems. It aims to see if this treatment can improve cognitive function without major side effects.
Hamilton, OntarioAges 60–90 - NCT05514106Enrolling by invitationPhase 4
MIBG heart scan study for aging and neurologic conditions
This Phase 4 study tests how an iodine-based heart scan (a special imaging test) works in people with certain neurologic diagnoses and aging-related conditions. It may help researchers better understand the heart-brain connection in these disorders and improve future care.
Rochester, MinnesotaAges 40–90 - NCT07169630RecruitingPhase 1
PET scan study for Alzheimer's or mild cognitive impairment
This study uses a special PET scan to look at a brain protein called PDE4 in people with Alzheimer's disease or mild cognitive impairment. It may help researchers understand how this protein is involved in memory and thinking problems.
Bethesda, MarylandAges 50–100 - NCT06733714Recruiting
Brain stimulation plus memory training for older adults
This study tests whether a gentle, non-invasive electrical current applied to the scalp (tACS) combined with computer-based brain exercises can improve memory and thinking in older adults who have concerns about their cognitive health.
Rio de Janeiro, Rio de JaneiroAges 50 years+ - NCT06179680Recruiting
White matter changes in memory problems or Alzheimer's
This study uses brain MRI scans to look at white matter changes in people with memory problems (amnestic mild cognitive impairment) or Alzheimer's disease. It aims to understand how these changes relate to memory loss.
San Donato Milanese, MilanoAges 65 years+ - NCT06650969Recruiting
Early detection of cognitive decline in type 2 diabetes
This study is looking at ways to catch early thinking and memory changes in people with type 2 diabetes. By joining, you may help doctors learn how to spot problems sooner and find better ways to help.
Nanjing, JiangsuAges 45 years+ - NCT07239310Recruiting
Device to improve memory and thinking in early Alzheimer's
This study tests a device called Neuclare that aims to temporarily boost memory and thinking skills in people with mild cognitive impairment or very early Alzheimer's disease. It could offer a non-drug way to help with daily mental tasks.
Cheonan, Chungcheongnam-doAges 55–90 - NCT07512362RecruitingPhase 2
Stem cells and antibodies for early Alzheimer's disease
This study tests whether human stem cells, combined with your existing Alzheimer's medication (Leqembi or Kisunla), can help slow memory loss and improve daily functioning in people with mild cognitive impairment or early Alzheimer's. You would receive a stem cell infusion as an add-on to your current treatment.
Miami, FloridaAges 55–90 - NCT06484244Recruiting
Walking and balance in memory loss
This study looks at how older adults with mild cognitive impairment or Alzheimer's disease adapt their walking. It aims to understand walking and balance to help people stay mobile and safe longer.
Atlanta, GeorgiaAges 50–90
Hear when a new Mild Cognitive Disorder trial opens
We’ll email you when one opens — at most once a week, no account needed, unsubscribe anytime.
Common questions
- Are there clinical trials for mild cognitive disorder?
- Yes. Clin2 currently lists 312 recruiting mild cognitive disorder studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a mild cognitive disorder trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a mild cognitive disorder trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
- Mild Cognitive Impairment
- Amnestic Mild Cognitive Impairment
- Cognitive Dysfunction, Cognitive Disorder
- Mild Cognitive Impairment (MCI) Amnestic
- Mild Cognitive Impairment (MCI) Due to Alzheimer's Disease
- Amnestic Mild Cognitive Disorder
- Mild Cognitive Impairment Due to Alzheimer's Disease
- Cognitive Impairment
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.