Clinical trials
Muscle Weakness clinical trials
Below are recruiting muscle weakness clinical trials, each written for real people, not researchers. We’re tracking 55 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT07688863Enrolling by invitation
Comparing breathing muscle training methods for heart failure
This trial compares two different types of breathing muscle training to see which works better for people with heart failure and weak breathing muscles. You may join if you have heart failure with reduced pumping ability and are stable overall.
Viña del Mar, ValparaisoAges 18 years+ - NCT07147933Recruiting
Treatment for crouch gait in cerebral palsy
This trial tests a treatment for children with cerebral palsy who have a crouched walking pattern, a forward-tilted pelvis, and weak calf muscles. It uses EMG to check muscle activity and aims to improve walking.
AmmanAges 4–10 - NCT05206838Recruiting
Treating gluteus medius tendon weakness after hip replacement
This trial looks at treating a specific hip muscle-tendon problem (gluteus medius insufficiency) after total hip replacement. It may help people who have had ongoing limping despite surgery by using an Achilles tendon–based approach.
MölndalAges 40–80 - NCT05216666Recruiting
Surgery type and leftover limping after hip replacement
This study looks at whether the kind of hip surgery approach affects how much limping remains after a total hip replacement. You may benefit by helping researchers find the approach that leads to better walking after surgery.
MölndalAges 40–80 - NCT07692126Recruiting
Neck pain and hand strength: core vs shoulder exercises
This study compares two types of exercises to see which better improves hand grip strength and neck pain. If you have had chronic myofascial neck pain (trigger points) in the upper shoulder muscle for over 6 months, this trial may help find which exercise works best for you.
Giza, Giza GovernorateAges 25–45 - NCT07362862Recruiting
Electrical muscle stimulation to prevent ICU weakness
This trial tests a wearable device that uses mild electrical pulses to stimulate leg muscles, helping prevent muscle weakness in ICU patients with severe infections. It may help you recover strength faster and avoid long-term disability.
Rochester, MinnesotaAges 18–85 - NCT06673953Recruiting
Breathing training for heart surgery recovery with neck posture problems
This trial tests whether a breathing exercise device can improve heart and lung function in men who had heart bypass surgery at least 3 months ago and also have neck pain from poor posture. It may help you breathe better and feel stronger after surgery.
Giza, Giza GovernorateAges 45–55 - NCT06631053Recruiting
Exercise program for 30 days of leg muscle disuse
This study looks at how a specific exercise program affects your muscles after a period of not using them (simulated by a leg brace). You'll wear a brace on one leg for 30 days and do certain exercises to see if they help prevent muscle loss.
Lexington, KentuckyAges 35–45 - NCT05536531Recruiting
NMES therapy to help prevent ICU muscle weakness
This trial tests whether a device that delivers small electrical pulses to muscles can help prevent breathing and muscle weakness in very sick ICU patients. It also looks at changes in blood markers that may relate to muscle weakness and recovery.
Santiago, Santiago MetropolitanAges 18 years+ - NCT03810768Recruiting
Metabolomics study of ICU-acquired weakness after surgery
This study looks at blood and body chemistry (called metabolomics) to understand and possibly predict muscle weakness that can happen in the ICU after surgery. It may help researchers find better ways to prevent or monitor this problem.
Vienna, State of ViennaAges 18 years+ - NCT07132736Recruiting
Underwater vs. regular exercise for quality of life and muscle power
This trial compares exercising underwater to doing regular aerobic exercise on land. It aims to see which type of exercise better improves muscle strength, energy levels, and overall quality of life in people with excess weight.
AmmanAges 18–50 - NCT07404956Recruiting
Comparing surgical and N95 masks for operating room nurses
This study checks how wearing a surgical mask or an N95 mask affects the air quality during surgery (called surgical smoke). It is for operating room nurses who work with surgical smoke regularly.
Bartın, BartınAges 18 years+ - NCT05537298Recruiting
Help for muscle recovery after serious ICU illness
This trial looks at how to improve muscle strength and function after a stay in the ICU for sepsis or acute respiratory failure. If you recover from the illness but your muscles become weak, this study may test an approach to help rebuild strength faster.
Birmingham, AlabamaAges 18 years+ - NCT07357662Recruiting
Exercise video games for foot strength and balance in older adults
This study tests how playing fun exercise video games (exergames) can improve foot muscle activity, balance, and ability to move around in older adults who are otherwise healthy.
Tarsus, Mersi̇nAges 65–80 - NCT07024095Recruiting
Breathing muscle training after back surgery for osteoporosis
This study tests whether a simple breathing-muscle training program can help people recover better after vertebroplasty surgery for a broken back caused by osteoporosis. It aims to improve your breathing strength and overall function.
Kayseri, KocasinanAges 50 years+ - NCT07761468Enrolling by invitation
Standardized medication dosing for ICU patients on ventilators
This study is testing a standardized way to adjust a medication used to help people on ventilators in the ICU. It aims to see if a more consistent dosing approach can help patients breathe better and possibly come off the ventilator sooner.
Querétaro City, QuerétaroAges 18 years+ - NCT05929755RecruitingPhase 4
Depo-Medrol after lumbar surgery through the psoas muscle
This trial studies whether a steroid shot called Depo-Medrol, given after a specific type of lower-back surgery, can improve recovery and outcomes. It’s only for people who are having a certain lumbar fusion procedure at specific spinal levels.
Farmington, ConnecticutAges 18–75 - NCT07166198Recruiting
Stopping age-related muscle weakness in women during inactivity
This study tests if a gentle hand exercise or a noninvasive brain stimulation can prevent muscle weakness in middle-aged women when they limit arm use for a period. It may help protect your strength and nerve function during recovery or downtime.
Manhattan, KansasAges 40–65 - NCT06487728Enrolling by invitation
Predicting muscle weakness in ICU patients with urine test
This study checks if a urine test and muscle measurements can help predict muscle weakness in critically ill patients. It aims to find an easier way to identify who might get weaker in the ICU.
Zagazig, Sharqia ProvinceAges 18 years+ - NCT06665607Recruiting
Foot muscle training for people with MS
This study tests whether training the small muscles in your feet can improve your walking and balance if you have multiple sclerosis (MS). It is for people with moderate disability, so you can still walk but may have some trouble.
ValladolidAges 18–70 - NCT06185179RecruitingEarly Phase 1
Metformin for muscle recovery in older adults
This study tests whether a common diabetes medicine called metformin can help your muscles recover faster after a minor injury. You may qualify if you are 60 or older, generally healthy, and not taking certain medicines.
Salt Lake City, UtahAges 60 years+ - NCT05919940Recruiting
Testing a muscle stimulation and extra protein plan in ICU patients
This trial tests whether electrical muscle stimulation plus extra protein (protein substitute) can improve muscle health and metabolism in critically ill adults in the ICU. If you’re newly admitted and expected to stay on a breathing machine for several days, it may help you keep more muscle strength during recovery.
Vienna, State of ViennaAges 18 years+ - NCT07243028Recruiting
Pelvic floor training with ultrasound and electrical feedback
This trial tests whether adding ultrasound and muscle-activity feedback to standard pelvic floor exercises helps women with pelvic floor problems like organ prolapse, stress incontinence, or difficulty emptying the bladder.
Tainan, TaiwanAges 21 years+ - NCT07538830Recruiting
Probiotic supplement for muscle strength in older adults
This study tests whether a specific probiotic (a beneficial bacteria called Lactiplantibacillus plantarum) can help improve muscle strength and physical function in adults aged 50–84. The probiotic may work by improving gut health, which could support muscle health.
BusanAges 50–85
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Common questions
- Are there clinical trials for muscle weakness?
- Yes. Clin2 currently lists 55 recruiting muscle weakness studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a muscle weakness trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a muscle weakness trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.