Clinical trials
Muscle clinical trials
Below are recruiting muscle clinical trials, each written for real people, not researchers. We’re tracking 1,162 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT06263153RecruitingPhase 2
Futibatinib and durvalumab before bladder cancer surgery
This trial tests two drugs (futibatinib and durvalumab) given before bladder removal surgery for people with muscle-invasive bladder cancer who cannot take standard cisplatin chemotherapy. The goal is to see if the combination shrinks the tumor and improves outcomes.
Ann Arbor, MichiganAges 18 years+ - NCT06280482RecruitingPhase 1
Nicotinamide Riboside for Moyamoya in Smooth Muscle Dysfunction
This trial tests a vitamin B3 supplement called nicotinamide riboside (NR) to see if it can help people with Smooth Muscle Dysfunction Syndrome (SMDS) who have a specific gene mutation. The goal is to improve blood flow problems in the brain (moyamoya-like disease) caused by the condition.
Houston, TexasAges 1 year+ - NCT06287541Recruiting
Do you need a second bladder surgery after a negative urine test?
This study looks at whether a second bladder surgery is still needed for people with high-risk bladder cancer who had a negative urine test after their first surgery.
Nanjing, JiangsuAges 18 years+ - NCT06316778Recruiting
Pelvic floor training for women with myotonic dystrophy
This study tests whether pelvic floor muscle training (exercises to strengthen the muscles that control urine flow) can help women with myotonic dystrophy type 1 who have bladder leakage. It's a gentle, non-surgical approach that may improve quality of life.
Jonquière, QuebecAges 18 years+ - NCT06319157Recruiting
Minimal access vs. standard back muscle flap for breast reconstruction
This study compares a less invasive method of harvesting the latissimus dorsi (a back muscle) for breast reconstruction. It is for early-stage breast cancer patients who have mild to moderate breast sagging and want to use their own tissue for reconstruction.
Guangzhou, GuangdongAges 18–70 - NCT06321965Recruiting
Study of SMA in Children on SMN-Boosting Therapies
This study is looking for children and teens with spinal muscular atrophy (SMA) who are already on a treatment like Spinraza, Evrysdi, or Zolgensma. The goal is to understand different forms of SMA and how the treatment affects them over time.
Bron, RhoneAges birth–16 years - NCT06334601Recruiting
Sleep apnea test to measure airway collapse and muscle response
This study looks at how the upper airway collapses and how muscles respond in people with obstructive sleep apnea (OSA) during sleep. It may help researchers understand why some treatments work better for some people.
MilanAges 18 years+ - NCT06351904RecruitingPhase 1
Testing RAG-01 for bladder cancer that returned after BCG treatment
This trial tests a new drug, RAG-01, for people with a type of bladder cancer called non-muscle-invasive bladder cancer (NMIBC) that has come back after BCG therapy. The drug is given through a catheter into the bladder, and the study aims to see if it can help control the cancer.
St Leonards, New South WalesAges 18–75 - NCT06370832Recruiting
Breathing muscle training for people waiting for a lung transplant
This study tests if a special breathing exercise (inspiratory muscle training) can strengthen your breathing muscles while you wait for a lung transplant. You'd do the training alongside your regular pulmonary rehab sessions.
Edmonton, AlbertaAges 18 years+ - NCT06417190RecruitingPhase 2
Bladder preservation trial for muscle-invasive bladder cancer with variant histology
This trial tests a bladder-sparing approach for people with muscle-invasive bladder cancer that has a variant histology type. The goal is to avoid removing the bladder by using a combination of treatments.
Los Angeles, CaliforniaAges 18 years+ - NCT06430775Recruiting
Long-term ACL recovery after surgery
This study is looking at how well the ACL heals after surgery in the long term. It helps researchers understand recovery patterns, so you may get a closer look at your knee's healing process.
Roeselare, West-VlaanderenAges 18–40 - NCT06466304Recruiting
Breathing muscle training for children with beta thalassemia major
This study tests whether special breathing exercises can help children with beta thalassemia major. It aims to strengthen the muscles used for breathing, which may improve overall health.
GizaAges 8–12 - NCT06470282RecruitingPhase 1/Phase 2
Drug combo plus radiation for muscle-invasive bladder cancer
This trial tests a combination of two drugs (enfortumab vedotin and pembrolizumab) plus radiation therapy for people with bladder cancer that has grown into the muscle layer. The goal is to see if this treatment can kill the cancer while avoiding the need for bladder removal surgery.
San Francisco, CaliforniaAges 18 years+ - NCT06471751Recruiting
Muscle training for moderate sleep apnea
This trial tests whether a 3-month program of muscle exercises for breathing and mouth strengthens the airway, to help people with moderate sleep apnea breathe better during sleep and possibly reduce their symptoms.
GrenobleAges 18 years+ - NCT06481540Recruiting
Smartphone app for cough training in Parkinson's
This trial tests a smartphone app called SpiroGym to help people with Parkinson's disease improve their cough strength. It aims to see if app-guided exercises can make coughing more effective for clearing the airway.
PragueAges 40–80 - NCT06490250Recruiting
Breathing vs. movement exercises for hypertrophic cardiomyopathy
This study compares two types of gentle exercises—breathing muscle training and a traditional Chinese movement practice called Baduanjin—to see which helps people with hypertrophic cardiomyopathy feel better and improve their daily life. If you have a thickened heart muscle but are stable and have mild symptoms, you may be able to join.
IstanbulAges 18 years+ - NCT06502392Recruiting
Muscle enzyme and pelvic floor strength after vaginal birth
This study looks at the link between a natural muscle enzyme (CPK) and pelvic floor muscle strength in women who recently gave birth vaginally. If you join, you will have a simple blood test and a muscle strength assessment to help understand recovery after childbirth.
GizaAges 25–35 - NCT06509594Recruiting
Exercises for neck pain from Upper Crossed Syndrome
This study compares two types of exercises—scapular stabilization exercises and eccentric muscle energy techniques—to see which works better for neck pain caused by Upper Crossed Syndrome. It's designed for people ages 18 to 35 with neck pain that isn't spreading into the arms or head.
Sargodha, Punjab ProvinceAges 18–35 - NCT06510231Recruiting
Breathing muscle training for heart failure with preserved ejection fraction
This study tests whether breathing muscle training can improve exercise capacity and symptoms in people with a type of heart failure called HFpEF. You may qualify if you are already on certain heart medications and are stable enough to exercise.
Rochester, MinnesotaAges 18 years+ - NCT06511648RecruitingPhase 2
Erdafitinib with or without immunotherapy for FGFR-altered bladder cancer
This trial tests a targeted therapy called erdafitinib, either alone or combined with an immunotherapy drug (cetrelimab), for people with muscle-invasive bladder cancer that has a specific FGFR gene change. It may be an option if you cannot take cisplatin chemotherapy and have not had prior treatment for this cancer.
Clermont-FerrandAges 18 years+ - NCT06519942Recruiting
Muscle and bone health in diabetes with nerve damage
This study looks at how diabetes and nerve damage affect your muscles and bones. It compares people with type 2 diabetes to healthy volunteers to learn more about these changes.
GhentAges 40–70 - NCT06521502Recruiting
Studying inflammation in the heart and lungs in the ICU
This study collects blood samples from people in the ICU with sudden heart or lung problems caused by inflammation. The goal is to learn more about these conditions and improve future treatments.
Fresno, CaliforniaAges 18 years+ - NCT06524193Recruiting
Comparing in-person vs online voice therapy for voice strain
This study compares the effectiveness of face-to-face voice therapy versus online voice therapy for muscle tension dysphonia (a voice disorder from throat muscle strain). It tests whether doing therapy via video call works just as well as in-person sessions.
Hong KongAges 18 years+ - NCT06532123Recruiting
Study on improving muscle control for bowel leakage
This trial tests a treatment to strengthen the muscles that control bowel movements in people with weak anal sphincters. It may help those who have trouble holding in stool or gas.
Milwaukee, WisconsinAges 18 years+
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Common questions
- Are there clinical trials for muscle?
- Yes. Clin2 currently lists 1,162 recruiting muscle studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a muscle trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a muscle trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.