Clinical trials
Muscle clinical trials
Below are recruiting muscle clinical trials, each written for real people, not researchers. We’re tracking 1,155 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT06571708RecruitingPhase 2
Chemo plus immunotherapy for muscle-invasive bladder cancer
This trial tests adding two immunotherapy drugs (cemiplimab and fianlimab) to standard chemotherapy (gemcitabine and cisplatin) for people with bladder cancer that has grown into the muscle layer but hasn't spread. The goal is to see if adding these immunotherapies helps shrink the tumor before surgery.
New York, New YorkAges 18 years+ - NCT06598618Recruiting
Comparing two therapies for kneecap pain
This study compares two types of hands-on treatments—Instrument-Assisted Soft Tissue Mobilization (IASTM) and Muscle Energy Technique—to see which works better for kneecap pain. It aims to find a therapy that can help reduce your pain and improve movement.
Rawalpindi, Punjab ProvinceAges 18–35 - NCT06627283Recruiting
Does breathing muscle training help tongue muscles?
This trial tests whether training the muscles you use to breathe can also improve your tongue muscle function. It looks for healthy adults between 18 and 65 who can follow instructions in French or Dutch.
LeuvenAges 18–65 - NCT06628674Recruiting
Online videos for recovery after rectal cancer surgery
This trial tests if watching online interactive videos can help people who have had surgery for stage I to III rectal cancer deal with common bowel problems after treatment. Your participation could lead to better support tools for other patients.
Taoyuan, 中和區Ages 20 years+ - NCT06630949Recruiting
Vitamin D3 and creatine for muscle health in older adults
This study tests whether taking a combination of vitamin D3 and creatine can help older adults with mild mobility problems maintain or improve their muscle function. If you have minor trouble with walking, stairs, or getting in/out of a car, this trial may offer a simple way to help keep your muscles strong.
Hamilton, OntarioAges 60 years+ - NCT06631820Recruiting
A study of epicatechin for muscle health in advanced kidney disease
This trial tests whether a natural supplement called epicatechin can improve muscle health in people with advanced chronic kidney disease (CKD). You may be able to join if you have low kidney function and are not planning to start dialysis or have a kidney transplant in the next 4 months.
Huddinge, Stockholm CountyAges 60 years+ - NCT06632964RecruitingPhase 1
Testing VT-101 for non-muscle invasive bladder cancer
This study tests a new drug called VT-101 for people with a type of bladder cancer that hasn't spread into the muscle wall. The goal is to see if the drug is safe and effective. It might be an option if you have already had a biopsy and are not eligible for or refuse surgery.
Xuzhou, JiangsuAges 18–75 - NCT06665607Recruiting
Foot muscle training for people with MS
This study tests whether training the small muscles in your feet can improve your walking and balance if you have multiple sclerosis (MS). It is for people with moderate disability, so you can still walk but may have some trouble.
ValladolidAges 18–70 - NCT06673875Recruiting
Pelvic floor training for stress urinary incontinence
This study tests whether special pelvic floor muscle exercises using modern tools can help women with stress urinary incontinence (leaking urine when you cough, sneeze, or exercise). It may offer a non-surgical way to strengthen the muscles that control urine flow.
Brno, Czech RepublicAges 18–80 - NCT06680492Recruiting
Nutrition and muscle health after weight loss surgery
This study looks at how nutrition affects muscle strength and function in people who have bariatric surgery. It may help you understand how to keep your muscles healthy after surgery.
Montreal, QuebecAges 18–65 - NCT06682728RecruitingPhase 2
Treating high-risk bladder cancer after surgery
This trial tests a combination of two drugs (sacituzumab govitecan and nivolumab) given after surgery to prevent the return of muscle-invasive bladder cancer. It is for patients whose cancer has a high chance of coming back despite surgery.
Orange, CaliforniaAges 18 years+ - NCT06705790Recruiting
Pelvic floor training for bladder, bowel, and sexual health after spinal cord injury
This study tests whether pelvic floor muscle exercises can improve bladder, bowel, and sexual function in people with a spinal cord injury. If you have ongoing symptoms in these areas and a stable health routine, this trial may help you learn ways to strengthen those muscles.
Vancouver, British ColumbiaAges 19 years+ - NCT06707532Recruiting
Muscle relaxants for safer heart rhythm treatment
This study tests if giving muscle relaxants before a heart ablation procedure can protect muscles from damage. Ablation uses energy to fix irregular heartbeats, and muscle relaxants might make it safer.
Wroclaw, Lower Silesian VoivodeshipAges 18–90 - NCT07302230Recruiting
Home exercise app for bladder cancer patients
This trial tests whether a home-based physical activity program using a smartphone app helps people with non-muscle invasive bladder cancer become more active compared to a health education group. It's designed for those who are not very active and want to improve their health.
Seattle, WashingtonAges 18 years+ - NCT06714240Recruiting
Extra protein to support muscle strength in ICU
This study tests whether giving extra protein through a feeding tube can help ICU patients maintain muscle strength. It may be an option for people who are expected to stay in the ICU for at least a week and need a breathing machine.
Hasselt, LimburgAges 18 years+ - NCT06719245Recruiting
Preventing post-amputation pain with targeted nerve surgery
This trial tests a surgical procedure called targeted muscle reinnervation (TMR) to prevent pain after a leg amputation. The goal is to see if rerouting nerves during amputation can reduce phantom limb pain or stump pain.
Amsterdam, North HollandAges 18–75 - NCT06731114Recruiting
Neck muscle release for cervicogenic headache relief
This trial tests whether releasing the sternocleidomastoid neck muscle on top of the usual suboccipital muscle release helps reduce headaches that start from the neck. If you have headaches with neck stiffness and pain rating of 4 or more, this study may help find a more effective treatment.
Rawalpindi, Punjab ProvinceAges 18–45 - NCT06732531RecruitingPhase 1/Phase 2
Testing a new drug for high-risk bladder cancer that came back after BCG
This clinical trial tests a new drug, BH011, for people with high-risk, non-muscle-invasive bladder cancer that has come back or not responded to BCG therapy. The goal is to see if the drug is safe and works well when given directly into the bladder, as an alternative to bladder removal surgery.
Beijing, Beijing MunicipalityAges 18 years+ - NCT06749002Recruiting
Functional training for turning after stroke
This trial tests whether adding functional muscle training to turning-specific exercises helps people who have had a stroke turn more easily. It may benefit those who can walk with supervision and have no major memory or other neurological problems.
Islamabad, Punjab ProvinceAges 45–60 - NCT06757829Recruiting
Lung function in sickle cell: testing Acu-TENS therapy
This study tests if a gentle electrical nerve stimulation treatment (called Acu-TENS) can help improve your lung function. It's for people with sickle cell disease who are not currently in pain or have other major health issues.
Dokki, Giza GovernorateAges 20–50 - NCT06777134Recruiting
Pelvic floor issues and leg strength in MS patients
This study looks at how pelvic floor problems relate to leg strength and function in people with multiple sclerosis. It may help understand how to better treat these issues.
Istanbul, IstanbulAges 18–65 - NCT06780423Recruiting
Muscle changes in colorectal cancer cachexia
This study compares muscle changes in people with colorectal cancer who have experienced weight loss (cachexia), those with colorectal cancer without weight loss, and healthy volunteers. Participants will have their trunk and leg muscles examined to understand how cachexia affects the body.
Diepenbeek, LimburgAges 18 years+ - NCT06781879RecruitingPhase 4
Comparing bladder medication vs surgery for returning low-grade bladder cancer
This trial tests whether a chemotherapy drug placed directly into the bladder (chemoablation) works as well as surgery followed by chemotherapy for people whose low-grade bladder tumors have come back. It aims to find a less invasive option that still controls the cancer.
AalborgAges 18 years+ - NCT06816836Recruiting
Measuring leg muscle mass to predict hospital stay after cancer surgery
This study uses ultrasound to measure leg muscle mass before surgery for gynecologic cancers, to see if it can predict how long you'll need to stay in the hospital after the operation.
Kolkata, West BengalAges 50–99
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Common questions
- Are there clinical trials for muscle?
- Yes. Clin2 currently lists 1,155 recruiting muscle studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a muscle trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a muscle trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.