Clinical trials
Muscle Loss clinical trials
Below are recruiting muscle loss clinical trials, each written for real people, not researchers. We’re tracking 28 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT06541548Recruiting
Bone health study for bone and muscle loss conditions
This study uses special imaging to compare bone structure in people with conditions that cause bone or muscle loss vs. those with back pain. It aims to better understand bone health in different diseases.
Saint-EtienneAges 18 years+ - NCT07303543Recruiting
Protein and exercise to prevent muscle loss after weight-loss surgery
This trial tests whether taking protein-collagen supplements and doing resistance exercises can help people maintain muscle after bariatric surgery. It may be a good fit if you are between 20 and 50 years old, have a BMI of 35 or higher, and are not pregnant or in menopause.
Istanbul, FatihAges 20–50 - NCT06630949Recruiting
Vitamin D3 and creatine for muscle health in older adults
This study tests whether taking a combination of vitamin D3 and creatine can help older adults with mild mobility problems maintain or improve their muscle function. If you have minor trouble with walking, stairs, or getting in/out of a car, this trial may offer a simple way to help keep your muscles strong.
Hamilton, OntarioAges 60 years+ - NCT06488872Recruiting
Using CT scans to check bone and muscle health in older adults
This study checks if CT scans can measure bone and muscle health as well as standard tests in older adults. If you've had a recent CT scan and simple strength or walking tests, your data may help improve care for seniors.
Basel, Canton of Basel-CityAges Any age - NCT06853275Recruiting
How movement speed affects muscle use in older adults with sarcopenia
This study tests whether giving you feedback on how fast you move during exercises can improve muscle activation and how you feel about your body. It is for older adults with sarcopenia who have not done resistance training recently.
Omaha, NebraskaAges 60–95 - NCT03208868Recruiting
Amino acid drink to help rebuild muscle in cirrhosis
This trial tests whether a special mix of amino acids (building blocks for muscle) can help reverse muscle loss in people with cirrhosis. It aims to improve muscle health while keeping you safe from known complications of liver disease.
Cleveland, OhioAges 18–70 - NCT05929508Recruiting
Rebuilding leg strength after above-knee amputation
This study tests a new approach to improve walking ability and leg function after an above-knee (transfemoral) amputation. It may help by targeting muscle loss and supporting safer, stronger mobility over time.
Chicago, IllinoisAges 18 years+ - NCT06728722Recruiting
Ultrasound for body measurement in critical care
This study uses ultrasound to measure body composition in women admitted to the Obstetrics and Gynecology critical care unit. It aims to see if ultrasound can help assess health status in critically ill patients.
Cairo, Cairo GovernorateAges 16 years+ - NCT05166499Recruiting
Amino acids to help rebuild muscle in liver cirrhosis
This trial tests whether a special amino-acid supplement can help reverse muscle loss in people with cirrhosis (scarring of the liver). It may help maintain or improve muscle strength and overall function, but eligibility depends on your liver status and overall health.
Cleveland, OhioAges 21–65 - NCT05647135Recruiting
High-protein tube feeds for multiple trauma ICU patients
This trial studies whether very high protein tube-feeding helps critically ill adults with multiple injuries recover better in the ICU. It compares feeding approaches during the time you need breathing support.
BucharestAges 18 years+ - NCT06535815Recruiting
Cyclic daytime feeding with ketogenic nighttime fasting for ICU patients
This trial tests a special feeding schedule where ICU patients receive nutrition during the day and fast at night, which may help their recovery. It aims to see if this approach is safe and beneficial.
Cologne, North Rhine-WestphaliaAges 18 years+ - NCT07325305Recruiting
Exercise to protect muscle in childhood leukemia
This trial tests whether starting physical activity and exercise early in treatment can help children with leukemia prevent muscle loss and reduce frailty. It involves wearing a Fitbit to track activity and may help kids stay stronger during and after treatment.
Melbourne, VictoriaAges 5–17 - NCT07059637Recruiting
Clinic for muscle loss in COPD patients
This study tests a new clinic designed to help people with COPD who have lost muscle mass (sarcopenia). By using a CT scan done during your hospital stay, doctors can identify muscle loss and offer treatments to help you regain strength and function.
Cleveland, OhioAges 40 years+ - NCT07101939RecruitingPhase 2
Studying a medicine to preserve muscle during weight loss
This trial tests a new medicine, (S)-pindolol benzoate, given along with semaglutide (Ozempic/Wegovy). The goal is to see if it helps people lose mostly fat instead of muscle while on a weight loss program.
BelgradeAges 18–75 - NCT07226947Recruiting
Exercise to prevent muscle loss with GLP-1 medication
This study looks at whether exercise can help prevent muscle loss in people taking GLP-1 medications (like Wegovy, Ozempic, or Mounjaro) for weight loss. It may help you keep your muscles strong while you lose weight.
Boston, MassachusettsAges 18–99 - NCT07443826RecruitingPhase 1/Phase 2
Gene therapy for age-related muscle loss and heart health
This trial tests a gene therapy that may help rebuild muscle and improve blood vessel growth in people ages 35 to 75. It's designed for those with stable health conditions and no history of cancer, heart disease, blood clots, or diabetes.
Coxen Hole, Bay IslandsAges 35–75 - NCT06611618Recruiting
Predicting fall risk in knee osteoarthritis using muscle tests
This study looks at how loss of muscle strength and control in people with knee osteoarthritis can predict falls. It uses tests and MRI to understand your risk, with the goal of helping prevent future falls.
BolognaAges 65–80 - NCT07294131RecruitingPhase 2
Preventing muscle loss in hospitalized older adults
This trial tests a special exercise approach using blood-flow restriction and a video game to help older adults in the hospital keep their muscle strength. The goal is to find a safe way for bedridden patients to exercise and recover better.
AntwerpAges 65 years+ - NCT07030582Recruiting
Online therapy for back pain and recovery after spinal fusion
This trial tests if internet-based cognitive behavioral therapy can help people recover better after lumbar fusion surgery by reducing pain, strengthening back muscles, and improving outlook on recovery. You can participate from home using WiFi.
Nantong, JiangsuAges 18–55 - NCT05716880RecruitingPhase 3
Keto-like diet supplements for muscle loss in nephrotic syndrome
This Phase 3 study tests a keto-like supplement (Ketosteril) to help prevent or slow muscle loss in people with nephrotic syndrome. It may help by improving nutrition when the kidneys are leaking large amounts of protein.
Warsaw, Masovian DistrictAges 18 years+ - NCT05856136RecruitingPhase 4
Study how opioid exposure affects diaphragm muscle function
This study looks at whether receiving opioids for pain during lower-leg surgery changes how well the diaphragm muscle (the main breathing muscle) works afterward. It compares breathing muscle function in people who do and do not have certain lung conditions.
Rochester, MinnesotaAges 18 years+ - NCT06129110Recruiting
Weight loss and muscle fat study for adults aged 18-70
This study looks at how losing weight affects the fat that sits inside your muscles (called intermuscular fat). It might help people with overweight to better understand how weight loss can improve muscle health.
Aurora, ColoradoAges 18–70 - NCT04320264Recruiting
Study tests muscle fuel patterns in adults with BMI 25–30
This study looks at how your muscles use fuel during exercise by measuring blood lactate. It may help researchers understand “metabolic inflexibility” and why some people rely more on fast, short-lasting energy during activity.
Greenville, North CarolinaAges 18–50 - NCT07393360Recruiting
Muscle preservation during weight loss with GLP-1 drugs
This trial tests a special medical food to help keep muscle mass while losing weight with GLP-1 medications like liraglutide, semaglutide, or tirzepatide. It's for adults with obesity or overweight with related health issues.
MilanAges 18–65
Hear when a new Muscle Loss trial opens
We’ll email you when one opens — at most once a week, no account needed, unsubscribe anytime.
Common questions
- Are there clinical trials for muscle loss?
- Yes. Clin2 currently lists 28 recruiting muscle loss studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a muscle loss trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a muscle loss trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.