Clinical trials
Musculoskeletal Diseases or Conditions clinical trials
Below are recruiting musculoskeletal diseases or conditions clinical trials, each written for real people, not researchers. We’re tracking 4,049 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT04798430Enrolling by invitationPhase 3
Study drug follow-up for LDL reduction in high-risk cholesterol patients
This Phase 3 study looks at the long-term safety and benefit of OLE LIB003 for people with very high cholesterol or heart disease risk who still need lower LDL (“bad cholesterol”). It’s likely a continuation study for participants who already did earlier LIB003 Phase 3 trials.
Evanston, IllinoisAges 10 years+ - NCT04786223Enrolling by invitationPhase 2
Testing an anti-inflammatory PET imaging treatment in memory loss
This Phase 2 study tests whether targeting “neuroinflammation” (inflammation in the brain) can help in Alzheimer’s disease and related memory disorders. You may help researchers by doing several brain scans (including a special PET/CT scan) along with MRI and amyloid imaging to understand what’s happening in the brain.
Rochester, MinnesotaAges 60 years+ - NCT04689854Enrolling by invitation
Cervical spine surgery implant study for neck disc problems
This trial studies specific neck (cervical) spine implants used during surgery for degenerative disc disease or neck instability, along with a particular kind of bone grafting and supporting hardware. It may help patients by testing whether these devices and the planned fusion approach work safely and effectively in real-world surgery.
Orange, CaliforniaAges 18 years+ - NCT04680130Enrolling by invitation
Study of brain, genetics, and clinical symptoms in neurodegenerative illness
This study looks at how your symptoms, brain imaging (MRI), and genetic factors relate to neurodegenerative conditions. It may help researchers better understand what causes these illnesses and how to classify them.
Rochester, MinnesotaAges 21 years+ - NCT04605263Enrolling by invitation
Deep brain stimulation for Parkinson’s walking and falls
This study tests a brain surgery treatment (deep brain stimulation) to help improve gait problems such as freezing of walking, gait instability, or falls in people with Parkinson’s disease. It may help people whose walking symptoms are not well controlled by levodopa (a common Parkinson’s medicine).
Phoenix, ArizonaAges 18–75 - NCT04418830Enrolling by invitation
Study of a spine cage implant for degenerative back problems
This trial studies how well specific lumbar (lower back) implant “cages” help fuse vertebrae in people with degenerative disc disease, spinal slippage, narrowing, curvature, or forward-bending deformity. It may help by testing an approach to improve stability and reduce symptoms after surgery.
La Jolla, CaliforniaAges 18 years+ - NCT04364295Enrolling by invitation
Patients who used SeaSpine products join a global registry
This registry collects information from people who have been treated with at least one SeaSpine product and had standard imaging and symptom surveys before and after surgery. It helps doctors understand outcomes over time and can support future improvements in care.
Durango, ColoradoAges Any age - NCT04147559Enrolling by invitation
Long-term follow-up for a specific hip replacement stem
This study checks how well a particular hip replacement stem (the PROFEMUR Preserve Classic Femoral Stem) and matching parts keep working over many years. You may be invited if you had that exact hip replacement combination and can return for long-term checkups.
Scottsdale, ArizonaAges 21 years+ - NCT04104659Enrolling by invitation
Tau PET scan study to map brain changes in Alzheimer’s
This study tests a PET scan “tracer” medicine called [18F]MK-6240 to see how tau protein changes show up in the brain. It may help researchers measure disease-related brain changes in people with normal thinking or mild dementia.
St Louis, MissouriAges 18 years+ - NCT04100486Enrolling by invitation
Testing a noninvasive device to measure your body signals
This study uses a noninvasive bioelectronic device to record your body’s automatic (involuntary) signals. The goal is to see how well the device can analyze these signals and how your body responds in a controlled setting.
Manhasset, New YorkAges 18–60 - NCT04064008Enrolling by invitation
Long-term follow-up for a specific hip revision stem
This study follows people who had a hip replacement redone (revision) because of bone healing problems or hardware removal, using a specific revision femoral stem. It checks how the stem does over time and follows up for up to 10 years after surgery.
OtwockAges Any age - NCT03815656Enrolling by invitation
Closed-loop deep brain stimulation for Parkinson’s medication side effects
This study tests a “smart,” closed-loop deep brain stimulation (DBS) system that adjusts stimulation based on your brain signals. It’s designed for people with Parkinson’s who get troubling medication side effects, with the hope of improving symptoms more smoothly.
Durham, North CarolinaAges 18–75 - NCT03687710Enrolling by invitation
Alzheimer’s registry for people with memory concerns or risk
This is a research registry that helps doctors compare how different memory and Alzheimer’s risk groups change over time. It may help researchers learn which people are more likely to develop Alzheimer’s and how to better track early changes.
New York, New YorkAges 18–99 - NCT03649490Enrolling by invitation
Testing new spinal implant materials for XLIF fusion
This study compares different advanced materials used in a specific spinal fusion surgery (XLIF). It aims to see which implant material helps the bone fuse well and safely over time.
Hartford, ConnecticutAges 18–80 - NCT03576573Enrolling by invitation
Follow-up study for specific hip replacement components
This study checks outcomes after a specific type of hip surgery using specific brand parts. You may help by sharing follow-up visit information so the sponsor can confirm the components work as expected in everyday patients.
BuxtehudeAges 21 years+ - NCT03385876Enrolling by invitation
Rapid whole genome sequencing for children with suspected genetic illness
This study quickly reads a child’s DNA using whole genome sequencing to look for genetic causes of symptoms. It may help families and doctors better understand an underlying genetic condition and guide medical care.
San Diego, CaliforniaAges Any age - NCT03149341Enrolling by invitation
MRI and computer-heart simulations for heart disease
This study uses MRI scans and computer simulations to learn more about how the heart and blood flow work in people with certain heart or lung conditions. It may help researchers better understand heart problems and improve future care.
Palo Alto, CaliforniaAges Any age
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Common questions
- Are there clinical trials for musculoskeletal diseases or conditions?
- Yes. Clin2 currently lists 4,049 recruiting musculoskeletal diseases or conditions studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a musculoskeletal diseases or conditions trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a musculoskeletal diseases or conditions trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.