Clinical trials
Neuralgia clinical trials
Below are recruiting neuralgia clinical trials, each written for real people, not researchers. We’re tracking 58 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT06796595Recruiting
Nerve recovery program for chronic pelvic nerve pain
This study tests a medical program designed to help nerves heal better after surgery for long-term pelvic or buttock nerve pain. It looks at results one year after a minimally invasive operation to free compressed nerves.
BordeauxAges 18 years+ - NCT05051072Recruiting
MRI study in adults with trigeminal neuralgia pain
This study uses a special MRI scan to look at how the trigeminal nerve system is working in people with essential trigeminal neuralgia (face pain) and whether there is nerve involvement. You may be asked to get MRI scans while resting, which can help doctors better understand the cause and guide future treatments.
ParisAges 18 years+ - NCT07758920RecruitingPhase 2
New tablet for long-term shingles pain
This trial tests a new tablet called HL-1186 for treating post-herpetic neuralgia (long-lasting pain after shingles). It compares the new drug to pregabalin, a standard treatment, to see if it's safer and more effective.
BeijingAges 18 years+ - NCT07712913RecruitingPhase 3
Pregabalin for nerve pain from diabetes or shingles
This trial tests an extended-release version of pregabalin (a pain medication) for people with long-term nerve pain caused by diabetes or shingles. It aims to see if this once-daily pill can reduce pain with fewer side effects.
Salvador, Estado de BahiaAges 18–75 - NCT07596485RecruitingPhase 1/Phase 2
RP-008 Plus Varenicline for Trigeminal Neuralgia Pain
This trial tests a new drug called RP-008 combined with varenicline (a quit-smoking medication) to relieve severe facial pain from trigeminal neuralgia. If you've already tried standard pain medications without enough relief, this combination might help reduce your pain attacks.
SherbrookeAges 18–80 - NCT05451251RecruitingPhase 1
Deep brain stimulation for severe trigeminal nerve pain
This trial tests whether deep brain stimulation can reduce intense facial pain from trigeminal neuralgia when medicines and prior procedures have not helped. You may be eligible if you’re an adult with a specific MRI finding near the trigeminal nerve pathway.
Sherbrooke, QuebecAges 18 years+ - NCT07565844Recruiting
Injected treatments for nerve pain after shingles
This trial tests three injected treatments—tiny cell particles, platelet-rich plasma, and steroids—directly into the skin to reduce long-lasting nerve pain that follows shingles. If you've had persistent shingles pain for at least 3 months, this study may help ease your discomfort.
Zagazig, ZagazigAges 18 years+ - NCT06644261RecruitingPhase 4
Comparing two methods of nerve block for pelvic pain
This study compares two ways to give a pudendal nerve block—one through the vagina, one through the buttock with X-ray guidance—to see which works better for women with pudendal neuralgia (nerve pain in the pelvic area). It may help find a more effective and comfortable treatment option.
Louisville, KentuckyAges 18 years+ - NCT06684275Recruiting
Radiofrequency treatment comparison for trigeminal neuralgia pain
This trial compares two types of radiofrequency treatment (pulsed and thermal) to see which works better for people with trigeminal neuralgia, a condition that causes severe, stabbing facial pain. If you have had facial pain for at least six months that isn't controlled by medicine, this study may help you find relief.
Zagazig, Sharqia ProvinceAges 18–60 - NCT06779578Recruiting
Comparing two types of radiofrequency for trigeminal neuralgia
This study compares two treatments (bipolar vs monopolar pulsed radiofrequency) for people with trigeminal neuralgia that hasn't improved with medication. It aims to see which method provides better pain relief.
AlexandriaAges Any age - NCT07400640Recruiting
Comparing two treatments for postherpetic neuralgia pain
This trial compares two procedures—a nerve block injection and a radiofrequency treatment—to see which works better for lasting pain after shingles. It aims to help people with persistent pain in the neck, chest, or lower back.
AnkaraAges 18–80 - NCT07390279Recruiting
Radiofrequency treatment for shingles-related nerve pain
This study tests a safe, non-surgical treatment called transcutaneous pulsed radiofrequency to see if it can help reduce nerve pain that continues after shingles. It targets the painful area through pads on the skin.
Istanbul, IstanbulAges 18 years+ - NCT05677243Recruiting
Observational study of radiosurgery for trigeminal neuralgia pain
This study follows people with trigeminal neuralgia to see how radiosurgery treatment affects their facial pain. It may help doctors better understand who benefits when medicines do not control the pain enough.
MonacoAges 18 years+ - NCT06492213Recruiting
Combining PRP with Radiofrequency for Face Nerve Pain
This study tests whether adding platelet-rich plasma (a concentrate from your own blood that may help healing) to a standard pulsed radiofrequency procedure reduces pain from infraorbital neuralgia more effectively than radiofrequency alone. It involves two treatments and follow-up for several months.
Beijing, Beijing MunicipalityAges 18–75 - NCT06261801Recruiting
Acupuncture plus pregabalin for shingles pain on the face
This trial tests whether adding acupuncture (electroacupuncture) to the standard pain medicine pregabalin can better relieve facial shingles pain that started 1 to 3 months ago. It's for people with moderate pain who are willing to try both treatments together.
Hangzhou, ZhejiangAges 18–85 - NCT07361796Recruiting
Venlafaxine to prevent nerve pain after shingles
This trial tests whether the drug venlafaxine, usually used for depression, can help prevent long-term nerve pain (postherpetic neuralgia) after a shingles infection. If you are currently experiencing shingles pain, joining this study might reduce your chances of developing chronic pain later.
BeijingAges 18 years+ - NCT07275762RecruitingPhase 2
Y-4 for postherpes nerve pain
This trial tests a new drug called Y-4 for people with lingering nerve pain after shingles (postherpetic neuralgia). If you have had pain for more than a month after your rash healed, this study may help find a new treatment option.
Nanjing, JiangsuAges 18 years+ - NCT07256145Recruiting
Ultrasound-guided nerve block for post-shingles pain
This study compares a new ultrasound-guided nerve block (erector spinae plane block) with standard care to help manage stubborn nerve pain after shingles. It might be an option if usual medications havent helped your pain.
Alexandria, AleexandriaAges 20–70 - NCT06472323Recruiting
Pulsed radiofrequency with platelet-rich plasma for trigeminal neuralgia
This trial tests a treatment that combines pulsed radiofrequency and platelet-rich plasma to see if it works better for trigeminal neuralgia pain that hasn't been helped by standard medicines like carbamazepine.
Beijing, Beijing MunicipalityAges 18–75 - NCT06863324Recruiting
Impact of radiation sensitivity on late side effects of facial pain radiosurgery
This study looks at whether how sensitive people are to radiation affects late side effects after radiosurgery for trigeminal neuralgia. It may help doctors better predict and prevent long-term problems.
Nice, Alpes-maritimesAges 18 years+ - NCT05152368RecruitingPhase 1
Tested umbilical cord stem cell exosomes for trigeminal nerve pain
This Phase 1 study tests whether a treatment made from donated umbilical cord stem cell “exosomes” is safe for people with trigeminal neuralgia (severe facial nerve pain). It mainly focuses on safety and tolerability, and it may help by calming nerve-related pain pathways.
St John'sAges Any age - NCT06896994Recruiting
Study of esketamine plus pregabalin and duloxetine for shingles nerve pain
This trial tests whether adding esketamine to two standard pain medicines (pregabalin and duloxetine) can better treat nerve pain from shingles that persists for months. It's for people whose pain hasn't improved enough with pregabalin alone.
Beijing, Beijing MunicipalityAges 18 years+ - NCT06890897Recruiting
Esketamine with pulsed radiofrequency for shingles-related face pain
This trial tests whether adding esketamine (a medicine related to ketamine) to a standard nerve treatment (pulsed radiofrequency) can better relieve face pain caused by shingles. It may help if you have ongoing, moderate-to-severe pain in your face or scalp.
BeijingAges 18 years+ - NCT06959147RecruitingPhase 4
Study for nerve pain after shingles using radiofrequency and a numbing shot
This trial tests a two-step procedure for treating nerve pain after shingles (called postherpetic neuralgia). First, a special type of radiofrequency treatment is applied to block the pain signals. Then, a long-lasting numbing medicine is injected under the skin to help keep the pain away. It is for people aged 40 to 85 who have not gotten enough relief from standard medicines.
Zunyi, GuizhouAges 40–85
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Common questions
- Are there clinical trials for neuralgia?
- Yes. Clin2 currently lists 58 recruiting neuralgia studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a neuralgia trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a neuralgia trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.