Clinical trials
Neuralgia clinical trials
Below are recruiting neuralgia clinical trials, each written for real people, not researchers. We’re tracking 67 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT05051072Recruiting
MRI study in adults with trigeminal neuralgia pain
This study uses a special MRI scan to look at how the trigeminal nerve system is working in people with essential trigeminal neuralgia (face pain) and whether there is nerve involvement. You may be asked to get MRI scans while resting, which can help doctors better understand the cause and guide future treatments.
ParisAges 18 years+ - NCT06620172Recruiting
Comparing two methods of nerve treatment for facial pain
This trial tests two image-guided procedures to treat severe facial pain from trigeminal neuralgia. It compares using a CT scan versus an X-ray video to guide a needle that heats the nerve to stop pain signals.
Zagazig, Sharqia ProvinceAges 18–60 - NCT06796595Recruiting
Nerve recovery program for chronic pelvic nerve pain
This study tests a medical program designed to help nerves heal better after surgery for long-term pelvic or buttock nerve pain. It looks at results one year after a minimally invasive operation to free compressed nerves.
BordeauxAges 18 years+ - NCT07758920RecruitingPhase 2
New tablet for long-term shingles pain
This trial tests a new tablet called HL-1186 for treating post-herpetic neuralgia (long-lasting pain after shingles). It compares the new drug to pregabalin, a standard treatment, to see if it's safer and more effective.
BeijingAges 18 years+ - NCT06492213Recruiting
Combining PRP with Radiofrequency for Face Nerve Pain
This study tests whether adding platelet-rich plasma (a concentrate from your own blood that may help healing) to a standard pulsed radiofrequency procedure reduces pain from infraorbital neuralgia more effectively than radiofrequency alone. It involves two treatments and follow-up for several months.
Beijing, Beijing MunicipalityAges 18–75 - NCT06863324Recruiting
Impact of radiation sensitivity on late side effects of facial pain radiosurgery
This study looks at whether how sensitive people are to radiation affects late side effects after radiosurgery for trigeminal neuralgia. It may help doctors better predict and prevent long-term problems.
Nice, Alpes-maritimesAges 18 years+ - NCT07446556Enrolling by invitation
Exercise program for women with pelvic nerve pain
This trial tests whether a structured exercise program can help women with pelvic nerve pain (pudendal neuralgia). If you have had this pain for at least 3 months and meet the other requirements, you may be able to join.
Martin, SlovakiaAges 18 years+ - NCT07123402Enrolling by invitationPhase 2
TRD205 for chronic pain after surgery
This trial tests a new tablet called TRD205 for people who have had long-lasting nerve pain after surgery (at least 3 months). The goal is to see if it can reduce pain safely.
BeijingAges 18–80 - NCT06578767Recruiting
Nerve release surgery for pelvic pain
This trial tests if robot-assisted surgery can relieve pain caused by trapped nerves in the pelvic area. It may help people who have not improved with medication.
Bordeaux, GirondeAges 18 years+ - NCT07712913RecruitingPhase 3
Pregabalin for nerve pain from diabetes or shingles
This trial tests an extended-release version of pregabalin (a pain medication) for people with long-term nerve pain caused by diabetes or shingles. It aims to see if this once-daily pill can reduce pain with fewer side effects.
Salvador, Estado de BahiaAges 18–75 - NCT05152368RecruitingPhase 1
Tested umbilical cord stem cell exosomes for trigeminal nerve pain
This Phase 1 study tests whether a treatment made from donated umbilical cord stem cell “exosomes” is safe for people with trigeminal neuralgia (severe facial nerve pain). It mainly focuses on safety and tolerability, and it may help by calming nerve-related pain pathways.
St John'sAges Any age - NCT05269472Recruiting
Study of nerve signals during facial pain procedures
This study measures nerve activity (electrical signals in nerves) in people who have trigeminal neuralgia and are getting a common facial pain procedure. It may help researchers better understand the condition and improve future treatments.
Minneapolis, MinnesotaAges 18 years+ - NCT05451251RecruitingPhase 1
Deep brain stimulation for severe trigeminal nerve pain
This trial tests whether deep brain stimulation can reduce intense facial pain from trigeminal neuralgia when medicines and prior procedures have not helped. You may be eligible if you’re an adult with a specific MRI finding near the trigeminal nerve pathway.
Sherbrooke, QuebecAges 18 years+ - NCT05677243Recruiting
Observational study of radiosurgery for trigeminal neuralgia pain
This study follows people with trigeminal neuralgia to see how radiosurgery treatment affects their facial pain. It may help doctors better understand who benefits when medicines do not control the pain enough.
MonacoAges 18 years+ - NCT06213155Recruiting
Freezing nerve pain in the face for trigeminal neuralgia
This study tests if freezing a facial nerve (cryoneurolysis) can lower trigeminal neuralgia pain. You may qualify if you have had daily pain attacks and standard medications haven't worked well.
TrondheimAges 18 years+ - NCT06216886RecruitingPhase 4
Botox injections for trigeminal neuralgia pain
This study tests Botox (onabotulinumtoxinA) injections to reduce pain attacks in people with trigeminal neuralgia who haven't gotten enough relief from medication or don't want surgery. You must have frequent attacks (more than 10 per week) and be on a stable medication dose.
Stanford, CaliforniaAges 18 years+ - NCT06261801Recruiting
Acupuncture plus pregabalin for shingles pain on the face
This trial tests whether adding acupuncture (electroacupuncture) to the standard pain medicine pregabalin can better relieve facial shingles pain that started 1 to 3 months ago. It's for people with moderate pain who are willing to try both treatments together.
Hangzhou, ZhejiangAges 18–85 - NCT06290661Recruiting
Nerve stimulation for shingles-related nerve pain
This study tests a treatment called peripheral nerve stimulation (using a small device to send mild electrical pulses) for people with nerve pain after shingles. It's designed for those whose pain is not well managed by usual treatments.
Wuhan, HubeiAges 18 years+ - NCT06357260Recruiting
Adding pregabalin to carbamazepine for trigeminal neuralgia
This trial tests whether adding pregabalin to your usual carbamazepine treatment can better control trigeminal neuralgia pain. It is for people with classic trigeminal neuralgia who want to see if a combination of medicines can help.
Rohtak, HaryanaAges 25–80 - NCT06420778Recruiting
Acupuncture for head and face nerve pain after shingles
This trial tests whether a gentle form of acupuncture (superficial needling with electroacupuncture) can relieve long-lasting nerve pain after shingles on the head and face. It may help if you have had head or face shingles and the pain has continued for a month or more.
Hangzhou, ZhejiangAges 50–80 - NCT06459466Recruiting
Exercise and neck mobilization for nerve-related arm pain
This study tests whether combining gentle exercises with specific neck joint movements can reduce pain and improve movement in people whose neck pain spreads into their arm. It's for people with a condition called cervicobrachial neuralgia (nerve-related neck and arm pain).
Rawalpindi, Punjab ProvinceAges 30–50 - NCT06461312Recruiting
Two nerve blocks for pudendal neuralgia pain relief
This study tests if combining two nerve blocks—one near the pudendal nerve and one at the ganglion impar—can better relieve chronic pelvic pain from pudendal neuralgia. The goal is to find a more effective treatment for people who haven't gotten enough relief from standard treatments.
Beijing, Beijing MunicipalityAges 18 years+ - NCT06472323Recruiting
Pulsed radiofrequency with platelet-rich plasma for trigeminal neuralgia
This trial tests a treatment that combines pulsed radiofrequency and platelet-rich plasma to see if it works better for trigeminal neuralgia pain that hasn't been helped by standard medicines like carbamazepine.
Beijing, Beijing MunicipalityAges 18–75 - NCT06644261RecruitingPhase 4
Comparing two methods of nerve block for pelvic pain
This study compares two ways to give a pudendal nerve block—one through the vagina, one through the buttock with X-ray guidance—to see which works better for women with pudendal neuralgia (nerve pain in the pelvic area). It may help find a more effective and comfortable treatment option.
Louisville, KentuckyAges 18 years+
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Common questions
- Are there clinical trials for neuralgia?
- Yes. Clin2 currently lists 67 recruiting neuralgia studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a neuralgia trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a neuralgia trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.