Clinical trials
Neurological Diseases or Conditions clinical trials
Below are recruiting neurological diseases or conditions clinical trials, each written for real people, not researchers. We’re tracking 4,555 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT04815694Recruiting
MRI-guided radiotherapy for rectal cancer
This trial tests whether using MRI scans to guide radiotherapy can improve treatment for people with a certain type of rectal cancer. It focuses on patients whose tumors have not spread to other parts of the body and who have specific tumor features seen on MRI.
Roma, RomaAges 18 years+ - NCT04786223Enrolling by invitationPhase 2
Testing an anti-inflammatory PET imaging treatment in memory loss
This Phase 2 study tests whether targeting “neuroinflammation” (inflammation in the brain) can help in Alzheimer’s disease and related memory disorders. You may help researchers by doing several brain scans (including a special PET/CT scan) along with MRI and amyloid imaging to understand what’s happening in the brain.
Rochester, MinnesotaAges 60 years+ - NCT04782258RecruitingPhase 3
Testing the safety of tolvaptan in children with ARPKD
This trial is for children from 28 days old up to 18 years who have a rare kidney disease called ARPKD. It will test if the drug tolvaptan is safe for them. The study helps find new treatment options for kids with this condition.
Washington D.C., District of ColumbiaAges 4 weeks–18 years - NCT04821154Recruiting
Testing outcomes after revision knee replacement with a Persona system
This study looks at how well a specific revision knee replacement system (the Persona system) works after earlier knee problems or surgeries. You may be eligible if you need a revision knee and can follow follow-up care instructions; the trial also checks for certain infection, bone, and health-safety factors.
Fayetteville, ArkansasAges 18 years+ - NCT04777357RecruitingPhase 3
Cariprazine for bipolar depression in ages 10 to 17
This Phase 3 study tests whether cariprazine can improve depression symptoms in children and teens with bipolar I disorder, and also tracks side effects. It may help if your depressive episode is ongoing and you meet specific mood and screening score requirements.
Bentonville, ArkansasAges 10–17 - NCT04808505RecruitingPhase 3
Study of enzyme therapy for children with infant-onset Pompe disease
This trial tests how well a new enzyme treatment (cipaglucosidase alfa with miglustat) works and how safe it is in children and babies with infant-onset Pompe disease. It may help by improving muscle function after earlier treatment or, for some babies, starting treatment when no prior enzyme therapy has been given.
Gainesville, FloridaAges Up to 17 years - NCT04798430Enrolling by invitationPhase 3
Study drug follow-up for LDL reduction in high-risk cholesterol patients
This Phase 3 study looks at the long-term safety and benefit of OLE LIB003 for people with very high cholesterol or heart disease risk who still need lower LDL (“bad cholesterol”). It’s likely a continuation study for participants who already did earlier LIB003 Phase 3 trials.
Evanston, IllinoisAges 10 years+ - NCT04816773Enrolling by invitation
Long-term follow-up for specific knee replacement parts
This study follows people for up to 10 years after a knee replacement done with specific manufacturer parts. It helps the company and doctors understand how well these knee implants work and whether they cause any long-term problems.
Fremont, CaliforniaAges 21 years+ - NCT04741230Recruiting
Test implant for severe corneal thinning to avoid transplant
This study tests a procedure called Xenia corneal lenticule in people with severe keratoconus or severe post-LASIK corneal thinning who want to avoid a corneal transplant. It aims to improve vision while checking safety and how well the new procedure works over time.
Wolverhampton, West MidlandsAges 18–79 - NCT04692675Recruiting
MRI study to track prostate cancer in active surveillance patients
This study uses special prostate MRI scans to see how prostate cancer changes over time while you stay on active surveillance. It also looks at prostate tissue to understand your cancer’s genetics, which may help guide future decisions.
Bethesda, MarylandAges 18 years+ - NCT04700657Recruiting
Study dryness patterns in eye graft-vs-host disease
This study looks at how common and how severe corneal nerve-related dryness is in people with chronic graft-vs-host disease (GVHD) after a stem cell transplant. It may help doctors understand which eye problems are most typical and how best to recognize them early.
Indianapolis, IndianaAges 18 years+ - NCT04735172Recruiting
Brain scan to compare Parkinson chemical signals in early patients
This study uses a special 7‑Tesla MRI brain scan to measure tiny chemical (metabolite) differences in specific deep brain areas. It compares newly diagnosed, early-stage Parkinson’s patients who are not on Parkinson medication with healthy volunteers.
Clermont-FerrandAges 18–75 - NCT04738422Enrolling by invitationPhase 2
Measuring airway acidity using exhaled air breath tests
This trial studies how “airway pH” (how acidic your breathing tubes are) changes after you drink or inhale an alkaline buffer, using special breath measurements. It may help researchers better understand and measure airway inflammation in people with lung conditions or in healthy non-smokers.
Indianapolis, IndianaAges 18–60 - NCT04755699RecruitingEarly Phase 1
Electrical stimulation study for hand or limb movement recovery
This early-stage study tests whether regular, skin-based electrical stimulation can help people with paralysis or weakness regain movement. You would attend frequent clinic sessions for months, while the team checks your ability to follow instructions and your safety.
Manhasset, New YorkAges 18–75 - NCT04743362Recruiting
Noninvasive scans for skin and mouth lesions
This trial tests noninvasive imaging methods to look at skin and mouth (mucosal) conditions. It may help doctors better see changes in these areas without taking tissue samples.
New York, New YorkAges Any age - NCT04722835Recruiting
Study lung immune cells in people at risk for COPD
This study looks at different lung immune cell patterns and how they work in smokers who are not yet diagnosed with COPD or asthma. It may help researchers understand why some people are more likely to develop COPD, which could guide future prevention or early treatments.
San Francisco, CaliforniaAges 40–75 - NCT04742634RecruitingPhase 1/Phase 2
Preemptive drug DEC-C after transplant to reduce hidden cancer
This trial tests whether giving DEC-C (a decitabine-based treatment) soon after an allogeneic transplant can improve outcomes for MDS patients who still have “measurable residual disease” (hidden leftover disease) detectable by a genetic test. It also compares this approach to standard observation if the hidden disease is not detected or if the higher-risk safety checks are not met.
St Louis, MissouriAges 18–75 - NCT04689854Enrolling by invitation
Cervical spine surgery implant study for neck disc problems
This trial studies specific neck (cervical) spine implants used during surgery for degenerative disc disease or neck instability, along with a particular kind of bone grafting and supporting hardware. It may help patients by testing whether these devices and the planned fusion approach work safely and effectively in real-world surgery.
Orange, CaliforniaAges 18 years+ - NCT04761120Recruiting
Follow-up study for specific heart valve repair ring implants
This study follows people who are going to get certain types of heart valve repair rings or bands. It aims to track safety and outcomes after the Abbott device is implanted in routine care over follow-up visits.
Durham, North CarolinaAges 18 years+ - NCT04679844Recruiting
Test bone putty for back fusion versus bone graft alternatives
This study compares a ready-to-use bone putty to standard bone graft materials (with or without your own bone) during back fusion surgery for unstable lower back problems. It looks at whether the putty works as well or better to help the bones fuse and heal.
Irvine, CaliforniaAges 18 years+ - NCT04604782RecruitingPhase 1/Phase 2
Regadenoson study in children to test safety and dosing
This trial tests how safe regadenoson is in children and how the body handles it after dosing. It also uses a heart “stress test” with MRI (CMR) when doctors feel it’s needed.
ParisAges 4 weeks–18 years - NCT04680130Enrolling by invitation
Study of brain, genetics, and clinical symptoms in neurodegenerative illness
This study looks at how your symptoms, brain imaging (MRI), and genetic factors relate to neurodegenerative conditions. It may help researchers better understand what causes these illnesses and how to classify them.
Rochester, MinnesotaAges 21 years+ - NCT04645602RecruitingPhase 2
Study of pembrolizumab and lenvatinib for lung papillomas
This early-phase trial tests how well pembrolizumab plus lenvatinib can treat respiratory papillomas that have spread to the lungs. It may help people whose lung disease is caused by human papillomavirus (HPV).
New Haven, ConnecticutAges 18 years+ - NCT04601038RecruitingPhase 2
Testing a stress-blocking drug for early Alzheimer's risk
This study tests a new medication, CORT108297, that may help protect the brain from the harmful effects of stress in people at risk for Alzheimer's disease. It is looking for adults age 55 and older who either have mild memory problems or are healthy but have a family history, APOE4 gene, or memory concerns.
Baltimore, MarylandAges 55 years+
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Common questions
- Are there clinical trials for neurological diseases or conditions?
- Yes. Clin2 currently lists 4,555 recruiting neurological diseases or conditions studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a neurological diseases or conditions trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a neurological diseases or conditions trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.