Clinical trials
Obese Adults clinical trials
Below are recruiting obese adults clinical trials, each written for real people, not researchers. We’re tracking 153 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT07020741Recruiting
Stable isotope study in adults with obesity
This study uses a special test (stable isotopes) to learn about how adults with obesity process food and energy. It may help researchers understand weight and metabolism better.
Urbana, IllinoisAges 19–59 - NCT06809166RecruitingPhase 4
Contrave for weight loss in adults with obesity
This study tests whether a weight loss medication called Contrave can help adults with obesity lose weight by changing how their body uses energy and handles food. If you qualify, you will take Contrave and be monitored for several months.
Ottawa, OntarioAges 18–64 - NCT05933499RecruitingPhase 2
Tirzepatide and bimagrumab for body fat and insulin sensitivity
This Phase 2 study tests two medicines to see how they change body fat, insulin sensitivity, and bone health in adults with obesity. It may help people who have tried lifestyle changes to lose weight but have not been able to, though diabetes and several health conditions must be ruled out first.
Boston, MassachusettsAges 18 years+ - NCT06886126RecruitingPhase 2
Testing HDM1005 injection for weight loss in adults with obesity
This study tests an experimental injection called HDM1005 for adults with obesity who do not have diabetes. The goal is to see if it helps with weight loss when combined with diet and exercise.
NanjingAges 18–65 - NCT06868862Recruiting
Exercise and fat loss in young women with overweight or obesity
This study compares two types of exercise (short bursts of intense activity vs. moderate continuous activity) to see which is better for fat loss in young women who have overweight or obesity. The exercises have the same total energy used, so the results can show which type might be more helpful for weight management.
São Paulo, São PauloAges 20–45 - NCT06626360Recruiting
Screening for malnutrition in people with obesity
This study looks at whether overweight or obese patients may also be malnourished. Researchers will screen people with a BMI of 25 or higher to find hidden malnutrition so they can get the right nutritional support.
AmsterdamAges 18 years+ - NCT06742112Recruiting
Arm and Breathing Test for People Who Are Overweight
This study looks at how well people who are overweight or obese can use their arms and breathe while performing a 6-minute pegboard and ring test. Researchers want to see if this test can help measure physical function in this group.
KırşehirAges 18–65 - NCT07513168RecruitingPhase 4
Low-dose semaglutide for weight loss in obese adults
This study tests whether a low dose of semaglutide (a once-weekly injection) can help obese adults without diabetes lose weight. Semaglutide works by reducing appetite and helping your body use food differently.
Hyderābād, SindhAges 18 years+ - NCT07396805Recruiting
Food is medicine study for obesity with food insecurity
This study tests whether providing healthy food and support can help adults with obesity and food insecurity lose weight. It looks at how food assistance programs might improve health.
Baltimore, MarylandAges 18 years+ - NCT07291232RecruitingPhase 1
Study of an injected drug for adults with obesity
This study tests an injected medication called ABBV-295 for adults with obesity. The goal is to see how safe it is and how the body processes it. You may join if you have a BMI between 30 and 45 and are generally healthy, and you haven't been on other weight loss treatments recently.
Anaheim, CaliforniaAges 18–65 - NCT07142707RecruitingPhase 1
Testing a new obesity drug for safety and effects
This study tests an investigational medication called MBX 4291 for adults with obesity. It aims to see if the drug is safe and how it works in the body, which could lead to a new weight-loss treatment option.
Doral, FloridaAges 18–65 - NCT06124456Recruiting
Vigorous vs. moderate exercise for liver fat reduction
This study compares high-intensity exercise to moderate-intensity exercise to see which is better at reducing fat in the liver for people with obesity and fatty liver disease.
Hong KongAges 18–69 - NCT07364175Recruiting
Weight loss drug study for young adults with high blood pressure
This trial tests if the weight loss medication tirzepatide can help young adults (18–40) with obesity and high blood pressure lower their blood pressure. It compares standard care to weight loss with tirzepatide.
Cambridge, CambridgeshireAges 18–40 - NCT07150975RecruitingPhase 3
Study comparing new weekly injection vs. Wegovy for weight loss
This trial tests a new weekly injection called GZR18 against the existing drug Wegovy for weight loss in adults who are overweight or obese. It aims to see which is more effective and safe for helping people lose weight and improve related health conditions.
BeijingAges 18 years+ - NCT07317115Recruiting
Comparing a new surgery to a diabetes drug for weight loss
This trial compares a new surgical procedure (duodeno-ileostomy) to a medication (semaglutide) for people with obesity and type 2 diabetes. It aims to see which approach works better for weight loss and blood sugar control.
Westmount, QuebecAges 18 years+ - NCT07721597RecruitingEarly Phase 1
Testing ZP6590 in Men of Various Weights
This trial tests an experimental medication called ZP6590 given as injections. It's for men who are at a normal weight, overweight, or have obesity, and studies how safe and well-tolerated the drug is in different doses.
Neuss, North Rhine-WestphaliaAges 18–60 - NCT07652333Recruiting
Strength training for muscle and mind on obesity medication
This study tests whether strength training can help adults taking new obesity medications (like Wegovy or Ozempic) maintain muscle and improve mental health. You would start the medication after your first study visit.
Pittsburgh, PennsylvaniaAges 18 years+ - NCT07205432RecruitingPhase 1
Testing XTL6001 in healthy and obese adults
This early-stage trial tests a new medication (XTL6001) in healthy and obese adults to see if it is safe. It is for people who are not diabetic, have no history of certain stomach, pancreas, or gallbladder problems, and have a BMI up to 40.
Beijing, Beijing MunicipalityAges 18–65 - NCT07062315Enrolling by invitation
Eating at the right time for belly fat reduction
This study tests a type of intermittent fasting where you eat only during a certain window that matches your body clock. The goal is to see if this helps reduce belly fat and improve metabolic health in people who are not very active and carry extra weight around the middle.
Hong KongAges 18–65 - NCT06380426Recruiting
Semaglutide for teens and adults with genetic obesity
This study looks at how semaglutide works in real life for people with obesity caused by a single gene change. If you or your teenager have this type of obesity and are taking or about to start semaglutide, you may be able to join.
ParisAges 12 years+ - NCT06599918RecruitingPhase 2
Nicotinamide for liver scarring in fatty liver disease
This study tests whether nicotinamide (a form of vitamin B3) can help reduce liver scarring in people with nonalcoholic fatty liver disease. You may qualify if you have moderate to severe liver scarring and are between 18 and 85 years old.
BarcelonaAges 18–85 - NCT07835360Recruiting
Body changes after starting GLP-1 medications for weight or diabetes
This study looks at how your body composition (muscle and fat) changes after you start a GLP-1 medication for obesity or type 2 diabetes. You will be followed for a year with body scans to see the effects.
Mexico City, Mexico CityAges 18 years+ - NCT06143956RecruitingPhase 2
Weight loss treatments for adults with obesity
This clinical trial tests new treatments for adults who are overweight or have obesity. The goal is to help people lose weight and improve their health.
Chandler, ArizonaAges 18–75 - NCT07792954RecruitingPhase 3
Weekly weight-loss study for Chinese adults with overweight or obesity
This study tests a once-weekly medicine called PF-08653944 to see if it helps Chinese adults lose weight compared to a placebo (a pill with no active medicine). It may be an option if you have been unable to lose weight through diet alone.
Hefei, AnhuiAges 18 years+
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Common questions
- Are there clinical trials for obese adults?
- Yes. Clin2 currently lists 153 recruiting obese adults studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a obese adults trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a obese adults trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.