Clinical trials
Obese clinical trials
Below are recruiting obese clinical trials, each written for real people, not researchers. We’re tracking 1,501 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT05235945Recruiting
Exercise program for people waiting for weight-loss surgery
This trial studies whether an exercise program can help people prepare for bariatric (weight-loss) surgery. It aims to see if exercise is safe and beneficial while you’re waiting for your surgery date.
LondonAges 18 years+ - NCT05275608Recruiting
Low-carb diet effects in people with metabolic syndrome
This trial studies whether a very low-calorie, low-carb diet (VLCKD) can improve metabolic health in adults with metabolic syndrome, fatty liver, and type 2 diabetes. It may help lower blood sugar and improve related health markers if you fit their specific diabetes and liver/kidney criteria.
Novara, ItalyAges 25–65 - NCT05279729Recruiting
Mobile app coaching for people with diabetes
This study tests whether using a smartphone app can help people with type 2 diabetes manage their health. It focuses especially on low-income Hispanic/Latinx adults who regularly check blood sugar.
San Diego, CaliforniaAges 18–64 - NCT05289310Recruiting
Home low-oxygen nights to study weight and health
This study looks at whether spending 8 hours each night in a low-oxygen tent for 8 weeks affects weight and related health in people with obesity. It also checks safety by monitoring oxygen levels and screening for breathing and heart-related conditions.
Baton Rouge, LouisianaAges 22–65 - NCT05301413RecruitingPhase 2
Diabetes prevention program tailored for Black adults at risk
This Phase 2 study tests a diabetes-prevention program designed for Black/African American adults, focusing on social factors that can affect health and weight. It aims to help participants lower their chances of developing type 2 diabetes through structured education and tracking.
Kansas City, MissouriAges 18 years+ - NCT05305313RecruitingPhase 4
Testing a new propofol dosing method for higher BMI surgeries
This trial studies whether adjusting how propofol (an anesthesia medicine) is dosed based on total body weight improves anesthesia delivery during longer surgeries. It mainly targets people with a higher body mass index having surgery that lasts over an hour.
New Delhi, National Capital Territory of DelhiAges 18–65 - NCT05309395RecruitingPhase 3
Food prescriptions to help Latino families eat affordably
This trial tests whether giving free/covered “food prescriptions” helps multigenerational Latino households lose weight by improving diet within a budget. It may help families who want to eat healthier without worrying as much about grocery costs.
Pasadena, CaliforniaAges 2 years+ - NCT05315752Recruiting
Body fat changes after CPAP-treated sleep apnea improves
This study looks at how bariatric (weight-loss) surgery may change body fat and body shape in people with severe obstructive sleep apnea who use CPAP. It aims to understand what may improve when sleep apnea is better controlled after surgery.
BrusselsAges 18–99 - NCT05316493RecruitingPhase 2/Phase 3
Weight-loss and progesterone treatments for early uterine lining disease
This trial studies a weight-management approach plus a progesterone-releasing IUD (LNG-IUS) and megestrol to treat endometrial atypical hyperplasia, a high-risk precancer of the uterine lining. It may help shrink or control the abnormal cells while supporting fertility or keeping the uterus.
ShanghaiAges 18–45 - NCT05316935RecruitingPhase 2/Phase 3
Hormone therapy for certain early uterine lining cancers without obesity
This trial tests whether adding GnRH medicine and letrozole to standard progestin treatment can better control early, low-risk endometrial cancer or atypical hyperplasia in people who are not obese. It may help some patients avoid progression while keeping the uterus, especially for those wanting future fertility.
Shanghai, Shanghai MunicipalityAges 18–45 - NCT05320796RecruitingPhase 4
Esomeprazole study after gastric bypass and pouch acid levels
This trial tests how well esomeprazole (a acid-reducing medicine) works after a Roux-en-Y gastric bypass, and how it changes the acidity in the stomach pouch. It may help confirm the best way to control stomach acid after bypass surgery.
Schlieren, SchlierenAges 18 years+ - NCT05330910Recruiting
Repair of a stomach valve during sleeve weight-loss surgery
This trial tests whether doing a specific repair near the stomach valve (the gastroesophageal junction) during laparoscopic sleeve gastrectomy can help people with a loose valve. It is aimed at adults who have a particular endoscopy finding (Hill grade III) and choose this weight-loss surgery.
SingaporeAges 21–65 - NCT05340868Recruiting
Study body response to oral semaglutide in overweight adults
This study looks at how genetics may affect your body’s early response to oral semaglutide, a weight-related diabetes medicine. You may be considered if you are overweight (or overweight with prediabetes) and can safely take part in the research.
Bialystok, Podlaskie VoivodeshipAges 18–65 - NCT05351476Recruiting
Exercise program for metabolism in postmenopausal women
This trial studies whether a structured exercise program can improve how your body uses fat. It is designed for postmenopausal women with higher weight and prediabetes who are not currently exercising much.
Tallahassee, FloridaAges 50–75 - NCT05353504Recruiting
Testing how gut changes affect food choices
This study looks at whether interventions that change your gut bacteria can change how you decide what to eat. It may help researchers understand the gut–brain link behind eating behavior.
LeipzigAges 18–60 - NCT05394363Recruiting
Victoria children birth-cohort study with parent/guardian consent
This study follows children born in a specific 2-year window and their parents or guardians over time. It helps researchers understand how children and families change as they grow, which can guide future health supports in Victoria.
Parkville, VictoriaAges 1 day+ - NCT05404061Recruiting
Study for people who don’t lose weight after bariatric surgery
This study looks at people who have had bariatric surgery but still struggle to lose weight (or lose it poorly). It aims to better understand how to help “poor responders” and what might be interfering with weight-loss results.
LondonAges 18–70 - NCT05414409RecruitingPhase 2
Gut microbiome study in young people with type 1 diabetes
This Phase 2 study looks at the gut microbiome (the bacteria in your intestines) in youth with type 1 diabetes, and how metformin may work differently through the gut. It may help researchers understand mechanisms and future treatment options.
Indianapolis, IndianaAges 11–18 - NCT05430178Recruiting
Study of liver fat changes in kids with fatty liver disease
This study looks at how metabolism works in children and teens who have (or do not have) nonalcoholic fatty liver disease (NAFLD), a condition where fat builds up in the liver. Participants may include healthy-weight controls, obese controls without NAFLD, and kids with NAFLD who are already scheduled for a liver biopsy for clinical reasons.
Oklahoma City, OklahomaAges 10–20 - NCT05432362Recruiting
Energy sensing brain study in depression and weight groups
This study tests how the brain and body respond to “energy sensing” in people with depression and in people with different body weights. You may be asked to do assessments and follow specific health and diet rules so the researchers can compare groups.
Graz, StyriaAges 18–40 - NCT05437809Recruiting
Study how people’s brains respond to ultra-processed foods
This study looks at how brain and body reward signals change after eating different ultra-processed foods. It may help researchers understand how food choices and metabolism relate to weight and mood in some people.
Philadelphia, PennsylvaniaAges 18–65 - NCT05443100Recruiting
Testing whole-body cold therapy for metabolic, neurologic, or fibromyalgia pain
This trial studies whether a whole-body cold therapy called “WBC” can help people with certain metabolic conditions, neurologic conditions, or fibromyalgia. You may be able to join if you meet age and weight requirements and don’t have certain medical or safety risks.
Oggebbio, Verbano-Cusio-OssolaAges 18–65 - NCT05464186Recruiting
Whole versus nonfat milk effects on kids’ body composition
This study compares whole milk vs nonfat milk to see how each affects body composition (such as fat and lean mass) in children. It may help families understand whether milk type makes a difference for healthy growth.
Boston, MassachusettsAges 9–12 - NCT05468437Recruiting
Online nutrition coaching for people with spinal cord injury
This study tests whether telenutrition (nutrition coaching by phone/tablet) can help people with spinal cord injury manage their weight and health. It may be a good fit if you’re mainly using a wheelchair, can use an iPad, and live in California.
San Jose, CaliforniaAges 20 years+
Hear when a new Obese trial opens
We’ll email you when one opens — at most once a week, no account needed, unsubscribe anytime.
Common questions
- Are there clinical trials for obese?
- Yes. Clin2 currently lists 1,501 recruiting obese studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a obese trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a obese trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.