Clinical trials
Obesity & Overweight clinical trials
Below are recruiting obesity & overweight clinical trials, each written for real people, not researchers. We’re tracking 494 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT06180837Recruiting
Can longer sleep improve heart health in overweight adults?
This study tests if getting more sleep (7+ hours) can lower certain fats in the blood called ceramides, which are linked to heart disease risk. It's for overweight adults who currently sleep less than 6.5 hours a night.
Salt Lake City, UtahAges 18–45 - NCT07849439Recruiting
Stair-climbing exercise snacks for overweight young adults
This study tests whether short bursts of stair climbing (called 'exercise snacks') done twice a week can improve metabolic health in young adults with overweight or obesity. You'll be asked to do stair-climbing sessions and might also consume a meal-replacement shake, so the researchers can see how your body responds.
St Louis, MissouriAges 18–35 - NCT07369011RecruitingPhase 3
Study of eloralintide for sleep apnea with obesity
This study tests an investigational medication called eloralintide to see if it can improve sleep apnea in people who are overweight or have obesity. You will receive either the study drug or a placebo (inactive shot), and your sleep and weight will be monitored over time.
Cullman, AlabamaAges 18 years+ - NCT07279194RecruitingPhase 3
Study of HDM1005 for weight loss in Chinese adults without diabetes
This trial tests a new medication, HDM1005, to help people with obesity or overweight who do not have diabetes lose weight. It is for Chinese adults who have a high body mass index (BMI) or a BMI above 24 with weight-related health problems like high blood pressure or fatty liver.
ShanghaiAges 18 years+ - NCT07037433RecruitingPhase 3
Heart protection study for people with heart disease and overweight
This study tests a new weekly injection (maridebart cafraglutide) to see if it helps lower the risk of heart problems in people with heart disease and overweight. It is for adults who have had a heart attack, stroke, or artery blockages and also have a BMI of 27 or higher.
Daphne, AlabamaAges 45–99 - NCT06768827Recruiting
Obesity mechanisms study for teens
This study looks at how bodies process food to understand obesity in teenagers. It may help find new ways to prevent or treat obesity.
New Haven, ConnecticutAges 15–22 - NCT06672939RecruitingPhase 3
Orforglipron for Weight Loss in Teens
This study tests a once-daily pill (orforglipron) to help adolescents with obesity or overweight plus related health problems lose weight. It offers a new option for teens who have struggled to lose weight with diet and exercise alone.
Oxnard, CaliforniaAges 12–17 - NCT07662330Recruiting
Spermidine for weight and cholesterol in overweight adults
This trial tests if a natural supplement called spermidine can help lower cholesterol and body weight in overweight people with high cholesterol. You cannot be on any cholesterol or diabetes medications.
Shanghai, Shanghai MunicipalityAges 18–60 - NCT07370350Recruiting
Ultrasound study of tongue in children with obesity
This study uses ultrasound (a safe, painless scan) to look at the tongue and how it moves in children and teenagers with obesity. Researchers want to learn more about tongue features that might affect breathing or weight, and the results could help improve care.
BrusselsAges 6–18 - NCT07229027Recruiting
Global overweight and obesity registry study
This study aims to develop better ways to measure how overweight or obesity affects your life, including severity, quality of life, and costs. You will fill out surveys to help researchers understand your experience.
Milton KeynesAges 18 years+ - NCT06967389Recruiting
Helping kids with severe obesity reduce heart risks
This trial tests whether semaglutide can lower heart disease risks in children with extreme obesity. It aims to improve weight and heart health over time.
Lexington, KentuckyAges 12–17 - NCT06722443Enrolling by invitation
Probiotics and Prebiotics for Obesity
This trial tests whether adding probiotics and prebiotics to your diet can help with obesity and related health problems like prediabetes, diabetes, high cholesterol, or high blood pressure.
Granada, SpainAges 18–75 - NCT07658560RecruitingPhase 2
Weight loss pill study for overweight or obese adults without diabetes
This study tests an experimental pill, BGM0504, to see if it helps overweight or obese adults lose weight safely. Participants will take the pill while continuing their usual diet and exercise routine.
Beijing, Beijing MunicipalityAges 18–55 - NCT07721597RecruitingEarly Phase 1
Testing ZP6590 in Men of Various Weights
This trial tests an experimental medication called ZP6590 given as injections. It's for men who are at a normal weight, overweight, or have obesity, and studies how safe and well-tolerated the drug is in different doses.
Neuss, North Rhine-WestphaliaAges 18–60 - NCT07575399RecruitingPhase 3
Switching to a New Weight-Loss Medication From Current GLP-1
This trial tests whether switching from your current GLP-1 medication (like Ozempic or Wegovy) to a new drug called maridebart cafraglutide works as well or better for weight management. You must have already lost at least 10% of your body weight on your current GLP-1 and be doing well with it.
Pelham, AlabamaAges 18–99 - NCT06937099RecruitingPhase 3
Testing two drugs for Crohn's with weight issues
This trial tests two study drugs, mirikizumab and tirzepatide, in people with moderate to severe Crohn's disease who also have overweight or obesity. The goal is to see if these treatments can help control Crohn's symptoms and inflammation.
Dothan, AlabamaAges 18–70 - NCT07808073RecruitingPhase 1
A weight-loss medicine study for people with overweight or obesity
This study tests an experimental medicine (LY4329090) to see if it can help people with overweight or obesity lose weight. You would be monitored closely for safety, and you may or may not receive the study drug.
Daytona Beach, FloridaAges 18–65 - NCT07803744RecruitingPhase 1
Study of tirzepatide for type 1 diabetes with overweight
This study tests a weekly injection called tirzepatide in people with type 1 diabetes who are overweight or have obesity. The goal is to see if it helps with blood sugar control and weight loss when added to insulin therapy.
Miami, FloridaAges 18–70 - NCT07743450RecruitingPhase 3
Daily oral medication for weight loss in adults with obesity and type 2 diabetes
This study tests a once-a-day pill for adults who are overweight or have obesity and also have type 2 diabetes. The goal is to see if the medication helps with weight loss and improves blood sugar control.
Birmingham, AlabamaAges 18 years+ - NCT07654972RecruitingPhase 1
Study of a new weight loss drug in healthy people with obesity or overweight
This study tests a new medication (LY4174794) for weight loss in people who are overweight or have obesity. It will help see if the drug is safe and how the body processes it.
San Antonio, TexasAges 18–65 - NCT07321886RecruitingPhase 3
Study of eloralintide for people with obesity or overweight
This trial tests if an investigational drug called eloralintide can help people with obesity or overweight lose weight. It is for people who do not have type 2 diabetes and who have tried but struggled to lose weight on their own.
Tuscaloosa, AlabamaAges 18 years+ - NCT07326111RecruitingPhase 4
Tirzepatide for PCOS and weight in women
This study tests if tirzepatide (a once-weekly injection) can improve periods and metabolic health in women with PCOS who are overweight. If you have PCOS, irregular cycles, and a BMI of 27 or higher, you might qualify.
BochumAges 18–45 - NCT07282600RecruitingPhase 3
Study of eloralintide for type 2 diabetes and weight
This study tests a new medicine called eloralintide for people with type 2 diabetes who are overweight or have obesity. It aims to see if the drug can help with weight loss and blood sugar control.
Birmingham, AlabamaAges 18 years+ - NCT07114289Recruiting
Breathing test methods for overweight patients on ventilators
This study compares two ways of testing if overweight or obese patients can breathe on their own after being on a ventilator. You will be randomly assigned to one of two breathing trials (pressure support or a T-piece) to see which works better for helping you get off the ventilator.
TaipeiAges 18 years+
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Common questions
- Are there clinical trials for obesity & overweight?
- Yes. Clin2 currently lists 494 recruiting obesity & overweight studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a obesity & overweight trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a obesity & overweight trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.