Clinical trials
Obesity clinical trials
Excess body weight that increases the risk of many other health conditions. We’re tracking 1,500 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT04838678RecruitingEarly Phase 1
Testing a new blood-pressure approach in obesity-related hypertension
This early-stage study tests a new way to help control high blood pressure that is linked to obesity. It may help people whose blood pressure is high based on a 24-hour blood pressure monitor.
Dallas, TexasAges 18–55 - NCT04844684Recruiting
Study hormones and bile acids in women with obesity
This study looks at how cortisol and bile acids are processed in non-menopausal women with obesity. The goal is to understand metabolism differences and potentially guide future treatments or dietary/medication approaches.
LilleAges 18 years+ - NCT04852198Recruiting
Compare two weight-loss surgeries in people with high BMI
This study compares two types of bariatric surgery to see which one works as well as the other for weight loss and health. You may be a candidate if you have a high BMI and specific related health problems, and if certain stomach and digestive issues don’t apply to you.
Almere StadAges 18–65 - NCT04854317Recruiting
Bariatric endoscopy for long-term weight management
This study tests a stomach procedure (endoscopy) to help people with obesity lose weight or control health problems linked to weight. You may be considered if other weight-loss efforts have not worked and surgery is not the best option for you.
OlbiaAges 18–70 - NCT04873258Recruiting
Test a non-invasive tool to screen for fat-related liver disease
This study looks at a new non-invasive screening method to predict metabolic dysfunction–associated steatotic liver disease (MASLD), a condition where fat builds up in the liver. The goal is to help identify people who may be at risk without needing invasive tests.
London, LondonAges 18–80 - NCT04883515Recruiting
Glutamine drink for insulin resistance and bowel symptoms
This trial studies whether taking an oral glutamine supplement can improve insulin resistance and reduce bowel-related problems in people with obesity and irritable bowel syndrome. It may help your blood sugar regulation and digestive comfort if you meet the criteria.
RouenAges 18–65 - NCT04893954Recruiting
Study of spine changes after weight loss from bariatric surgery
This study looks at how rapid weight loss after bariatric surgery may affect your spine over the following year or more. It may help doctors better predict who gets spine-related problems or improvements after surgery.
ParisAges 18 years+ - NCT04934228RecruitingPhase 1
Study targeting inflammation in people with obesity and high blood pressure
This Phase 1 study looks at a treatment aimed at reducing “inflammation patterns” that are common in obesity and insulin resistance. If you meet specific health and lab criteria, you may be asked to visit a research lab and provide blood samples to see how the treatment affects your body.
Kansas City, KansasAges 18–79 - NCT04941651Recruiting
Tele-nutrition program for weight and heart risk
This trial studies whether remote (phone/internet) nutrition coaching helps adults with obesity and/or higher risk for heart and blood vessel problems. It aims to improve weight and related health risks using regular telenutrition support.
ParisAges 18–75 - NCT04942093Recruiting
High-protein low-calorie diet before weight-loss surgery
This trial studies whether a higher-protein, lower-calorie diet before sleeve gastrectomy (a type of weight-loss surgery) changes outcomes after surgery. You may be able to join if you’re scheduled for the operation and meet specific health and safety requirements.
DieppeAges 18–65 - NCT04990024Recruiting
Diet trial for people with obesity using semaglutide
This study compares different diets to see how they affect “arterial stiffness” (how hard the blood vessels are) in people with obesity who are starting semaglutide for weight management. It may help find a diet approach that improves heart and blood-vessel health while you use semaglutide.
Beirut, Riad El SolhAges 18–49 - NCT05028309Recruiting
Study how obesity affects breathing and exercise in older adults
This study compares how body weight (higher or lower body fat) affects lung function, breathing during exercise, and exercise capacity in adults ages 65–75. You may be asked to do lung and exercise testing, but only if you meet health and activity restrictions.
Dallas, TexasAges 65–75 - NCT05028205Recruiting
Fruit and vegetable voucher program for kids
This trial tests whether giving families vouchers for fruits and vegetables helps improve children’s eating and health. It focuses on children ages 4–10 who have higher body weight for their age and who can participate with an adult caregiver.
Knoxville, TennesseeAges 4–10 - NCT05077579Recruiting
Alzheimer’s scan study for people with higher body weight
This study uses brain scans (MRI and two special PET scans) to see how Alzheimer’s-related changes show up in people who are overweight or obese, with different blood-sugar and insulin patterns. It may help researchers understand whether body weight and metabolism affect early Alzheimer’s markers in the brain.
St Louis, MissouriAges 40–60 - NCT05107908Recruiting
Test brain and behavior effects of a hidden message on eating
This study tests whether a subtle “priming” approach can improve eating behaviors in people with obesity. It also looks at brain activity during the process to understand how the approach may work.
Aurora, ColoradoAges 18–65 - NCT05120492Recruiting
Program for severe knee arthritis and extreme weight
This feasibility study tests a practical approach to help people with very severe knee arthritis and very high body weight. It aims to find an effective and safe way to manage both conditions together in real-world care.
Halifax, Nova ScotiaAges 18–65 - NCT05124808Recruiting
Tight blood sugar targets in pregnant women with gestational diabetes
This study compares a tighter blood sugar goal versus a standard goal in pregnant people with gestational diabetes who are also overweight or obese. It may help find whether stricter blood sugar control improves pregnancy outcomes.
Birmingham, AlabamaAges 18–45 - NCT05125822Recruiting
Study of how bodies change weight in youth with obesity
This study looks at what helps or drives weight changes in children and teens with obesity. You may be asked about growth and body changes to better understand why weight changes happen and how to manage them.
Chicago, IllinoisAges 11–15 - NCT05143697Recruiting
Coaching program to help young children reduce excess weight
This trial tests a family wellness coaching program using motivational interview counseling and referrals. It may help families support healthier habits for children ages 2 to 8 who have weight above a recommended range.
Pasadena, CaliforniaAges 2–8 - NCT05165706Recruiting
Study of how obesity affects insulin resistance over time
This study follows adults over time to understand how weight and body chemistry relate to insulin resistance. It may help researchers learn why insulin resistance happens and what could prevent or improve it.
Stanford, CaliforniaAges 35–65 - NCT05223530Recruiting
Study of how pregnancy programs future child health
This study follows mothers who previously joined two specific pregnancy research programs, to understand why some children may be more likely to develop weight and heart-related health problems later. If you were part of those original studies, your information could help researchers look for early predictors and prevention ideas.
HelsinkiAges 11–55 - NCT05225233Recruiting
Brain stimulation plus training to help reduce impulsive eating and weight
This study tests whether a brain stimulation method (tDCS) combined with cognitive training can reduce impulsivity around food and improve weight in Veterans with obesity. You would join a MOVE! weight program and complete study procedures to see whether this approach helps.
Minneapolis, MinnesotaAges 18–80 - NCT05237089Recruiting
Electroacupuncture for weight loss in people with prediabetes
This trial studies whether electroacupuncture can help reduce weight in adults who have obesity and blood sugar levels in the prediabetes range. You might be eligible if your weight has been stable and you don’t have certain medical or skin problems.
Shanghai, Shanghai MunicipalityAges 18–65 - NCT05237440Recruiting
Childhood trauma and stress hormones in women with obesity
This study looks at how childhood trauma might affect stress hormones (cortisol) and inflammation in women with obesity. It aims to find connections that could lead to better treatments.
LimogesAges 18 years+
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Common questions
- Are there clinical trials for obesity?
- Yes. Clin2 currently lists 1,500 recruiting obesity studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a obesity trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a obesity trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.