Clinical trials
Obesity clinical trials
Excess body weight that increases the risk of many other health conditions. We’re tracking 1,434 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT07654439Recruiting
Mixed reality tests for overweight and obese adults
This trial tests if mixed reality (combining real and virtual worlds) performance tests are valid and reliable for overweight and obese adults. You may be able to help researchers improve these tests if you are overweight or obese.
Konya, SelcukluAges 18–65 - NCT07654179Recruiting
Metformin for depression with obesity: a genetic study
This trial tests if adding metformin to antidepressants helps people who have both depression and obesity. It also looks at genetic factors that might affect treatment response.
Rawalpindi, Punjab ProvinceAges Any age - NCT07641361Recruiting
Staying Hydrated to Feel Better on GLP-1 Medication
This study tests whether drinking more water helps reduce uncomfortable side effects (like nausea and vomiting) when you first start taking GLP-1 medications for weight loss or diabetes. You'll be asked to follow a hydration plan and report how you feel.
Buffalo, New YorkAges 18–60 - NCT07640139Enrolling by invitation
Study of Weight-Loss Medications' Health and Cost Effects
This research study looks at how obesity medications affect people's health outcomes and healthcare costs. Researchers will track employees and their family members covered by participating Indiana employers to understand whether these medications help improve conditions like diabetes and heart health.
Indianapolis, IndianaAges 18–64 - NCT07633639Recruiting
GLP-1 Medicine After Weight-Loss Surgery in Chinese Patients
This trial tests whether adding a GLP-1 medication (a type of diabetes and weight-loss drug) after weight-loss surgery helps patients with obesity and related health conditions like diabetes. Researchers want to see if combining surgery with this medicine works better than surgery alone.
BeijingAges 18–60 - NCT07628127RecruitingPhase 1
Weight loss pill study for adults with excess weight
This study tests an experimental pill that may help people with overweight or obesity lose weight. It compares the pill alone or with another medication to see if it is safe and works well.
BrisbaneAges 18–60 - NCT07624071RecruitingPhase 1
Testing ALN-6222 for weight management in adults
This Phase 1 trial tests a new medicine called ALN-6222 in people with obesity to see if it's safe and how well it works. The study focuses on adults with a BMI between 30 and 40 who don't have diabetes.
Mount RoyalAges 18–65 - NCT07627919Recruiting
Strength training and high-protein diet for frail older women
This study tests whether combining resistance exercises with a protein-rich diet can improve muscle strength and overall function in older women with weak muscles. You would attend supervised workouts and follow a specific eating plan for several weeks.
El-Sheikh Zayed CityAges 60–70 - NCT06673550Recruiting
Best filling volume for stomach balloon in weight loss
This trial tests how much fluid should be used to fill a stomach balloon to help people with overweight or obesity lose weight. The goal is to find which volume works best and is safest.
OlbiaAges 18–80 - NCT04184479Recruiting
Test of a LEVAmethod program for adults with overweight
This study tests whether the LEVAmethod program helps adults with overweight or obesity when delivered in primary care. You may be asked to use digital tools and complete follow-up during the program.
GothenburgAges 18–75 - NCT07618741Recruiting
Improving AF Ablation Outcomes in Patients with Obesity
This study tests whether special care strategies can help obese patients have better results after a catheter ablation procedure for atrial fibrillation (a heart rhythm problem). Catheter ablation uses heat or cold to fix the irregular heartbeats.
TaipeiAges 20 years+ - NCT05281016Recruiting
Online family program to help children with weight
This study tests an online, family-based program (called the LITE Programme) to help children who are overweight. It may help improve healthy habits at home and support weight management.
SingaporeAges 6–12 - NCT07611240Recruiting
Comparing two anesthesia types for spine surgery in overweight patients
This study compares two common anesthesia medicines—sevoflurane (inhaled gas) and propofol (IV liquid)—to see which works better for people with obesity having lower-back spine surgery. The goal is to understand which anesthetic is safer and more effective for this group.
ErzurumAges 18–65 - NCT05165706Recruiting
Study of how obesity affects insulin resistance over time
This study follows adults over time to understand how weight and body chemistry relate to insulin resistance. It may help researchers learn why insulin resistance happens and what could prevent or improve it.
Stanford, CaliforniaAges 35–65 - NCT05912621RecruitingPhase 2
Tirzepatide for fat-related body dysfunction in overweight adults
This Phase 2 study tests whether tirzepatide can improve how your body handles fat (especially in people with overweight or obesity) and reduce fat-related “lipotoxicity.” It may help with body fat function and related health markers, but you must meet specific health and medication rules.
Palo Alto, CaliforniaAges 18–70 - NCT07598981Recruiting
Obesity Medication Safety and Effectiveness Registry
This registry tracks how well obesity medications work and their safety in real-world use. You'll share your health information and experiences with your obesity medication over time to help doctors understand what works best for different people.
Waltham, MassachusettsAges 18 years+ - NCT07597018RecruitingPhase 1
Comparing Blood Levels of Cagrilintide Versions in Adults With Overweight
This early-stage study tests different formulations of cagrilintide, a new medication, to see how the body absorbs and processes each version. Cagrilintide may help with weight management. Researchers will measure blood levels after you receive multiple doses.
BerlinAges 18–64 - NCT06716125Recruiting
Lifestyle changes for obese men with sexual and hearing issues
This trial tests whether lifestyle changes can help obese men who have both sexual difficulties and ringing in the ears. It might improve your overall health and these symptoms.
Dokki, Giza GovernorateAges 35–45 - NCT07589608RecruitingPhase 2
Weight Loss Study With Two New Injectable Medications
This study tests two new injectable drugs (macupatide and eloralintide) alone or together to help adults with obesity or excess weight lose weight. The goal is to see if these medications are safe and effective for weight management.
Chandler, ArizonaAges 18–75 - NCT07594093RecruitingPhase 1
A study of REGN20934 for adults with overweight or obesity
This trial tests a new medication, REGN20934, to see how safe it is and how it works in the body for adults who are overweight or have obesity. It may help if you are looking for new treatment options.
Glendale, CaliforniaAges 18–65 - NCT07582016Recruiting
Weight loss support for adults with obesity
This study tests a program to help adults with obesity lose weight using text messages, educational materials, and support. It aims to see if this approach helps people make healthy changes.
Salt Lake City, UtahAges 18 years+ - NCT07570758RecruitingPhase 2
Testing ERX1000 to Help Adults Manage Obesity
This study tests whether a new medication called ERX1000 is safe and well-tolerated in adults with obesity. The trial will help doctors understand if this treatment could be helpful for weight management.
Louisville, KentuckyAges 18–60 - NCT07575399RecruitingPhase 3
Switching to a New Weight-Loss Medication From Current GLP-1
This trial tests whether switching from your current GLP-1 medication (like Ozempic or Wegovy) to a new drug called maridebart cafraglutide works as well or better for weight management. You must have already lost at least 10% of your body weight on your current GLP-1 and be doing well with it.
Pelham, AlabamaAges 18–99 - NCT07575438RecruitingPhase 2
Fish oil types for reducing diabetes risk
This study tests whether different types of fish oil can improve blood sugar and cholesterol levels in people at high risk for type 2 diabetes. The goal is to see if one type of fish oil is better at reducing diabetes risk.
Montreal, QuebecAges 40–70
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Common questions
- Are there clinical trials for obesity?
- Yes. Clin2 currently lists 1,434 recruiting obesity studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a obesity trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a obesity trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.