Clinical trials
Obesity clinical trials
Excess body weight that increases the risk of many other health conditions. We’re tracking 1,434 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT06252220RecruitingPhase 1
Testing a new drug for obesity in healthy adults
This trial tests a new medication called DA-1726 for people with obesity but no other major health problems. It aims to see if the drug is safe and how it works in the body. You may qualify if your body mass index (BMI) is between 30 and 45 and your weight has been stable for 3 months.
Miami, FloridaAges 18–65 - NCT06208345Recruiting
Early e-health support for kids with obesity
This study tests an e-health program for children with a very high BMI. It aims to help families manage weight early in life through online support.
BernAges 6–12 - NCT05772052Recruiting
Study taste and eating changes in adults with obesity
This trial looks at how eating patterns and taste perception differ in people with obesity. It may help researchers understand what influences appetite and taste, which could improve future treatments.
MilanAges 18–60 - NCT06199154RecruitingEarly Phase 1
Inducing labor in women with severe obesity
This study tests starting labor in women with a BMI of 40 or higher. The goal is to learn if certain methods are safe and effective for this group.
Baltimore, MarylandAges 18 years+ - NCT06186869Recruiting
Diet and exercise for fatty liver disease
This study tests whether combining diet with two different exercise programs can help people who are overweight or obese and have fatty liver disease. The goal is to see which program works best to reduce liver fat and improve health.
Castellana Grotte, BariAges 18–65 - NCT06180837Recruiting
Can longer sleep improve heart health in overweight adults?
This study tests if getting more sleep (7+ hours) can lower certain fats in the blood called ceramides, which are linked to heart disease risk. It's for overweight adults who currently sleep less than 6.5 hours a night.
Salt Lake City, UtahAges 18–45 - NCT06143956RecruitingPhase 2
Weight loss treatments for adults with obesity
This clinical trial tests new treatments for adults who are overweight or have obesity. The goal is to help people lose weight and improve their health.
Chandler, ArizonaAges 18–75 - NCT06138821Recruiting
Endoscopic sleeve gastroplasty for obesity and MASH
This study tests if a procedure called endoscopic sleeve gastroplasty helps people with obesity and a liver condition called MASH lose weight and improve their liver health. It might be an option if you have both obesity and MASH and haven't had weight-loss surgery before.
Boston, MassachusettsAges 18 years+ - NCT06137365RecruitingPhase 2
Cannabis for Obesity Treatment Study
This study tests whether a cannabis product can help with weight loss in people with obesity. It is for those who have not used cannabis recently and are generally healthy.
Lexington, KentuckyAges 18–65 - NCT06116422Recruiting
Food Insecurity Program for Healthy Baby Weight
This study tests a program to help families with food insecurity and early signs of obesity in infants. It aims to learn the best ways to support healthy weight in babies at risk for overweight.
Durham, North CarolinaAges 1–2 - NCT06119516Recruiting
Guiding breathing machine settings for severe obesity and lung injury
This study tests a new way of setting the breathing machine for people with severe obesity and lung injury (ARDS). It aims to measure pressure inside the lungs more directly, which could help customize ventilation and improve outcomes.
AngersAges 18 years+ - NCT02602769Recruiting
Testing blood traits in children with ROHHAD syndrome
This trial studies children with ROHHAD syndrome to better understand their body chemistry and other blood features. The results may help researchers learn what drives the condition and how it might be tracked over time.
Boston, New YorkAges 2–20 - NCT01998750Recruiting
Study of genes in severe early childhood obesity
This study looks for genetic (inherited) reasons for severe obesity that starts in very early childhood. It may help doctors better understand the cause of your child’s weight gain and guide future treatment.
Boston, MassachusettsAges Up to 80 years - NCT06073704Recruiting
Light therapy for gum disease in people with obesity
This study tests whether adding a special light-activated cleaning (antimicrobial photodynamic therapy) to standard gum disease treatment can help people with obesity who have gum disease. It aims to see if this extra step improves gum health more than standard treatment alone.
Bauru, São PauloAges 18–70 - NCT06067763Enrolling by invitation
Project Health: Preventing unhealthy weight gain in young adults
This study tests a program to help young adults improve their eating and exercise habits, with the goal of preventing obesity. It is designed for people who are concerned about their weight and want to make healthier lifestyle choices.
Stanford, CaliforniaAges 17–20 - NCT04578652RecruitingPhase 3
Test fiber plus metformin for teen weight and insulin resistance
This trial studies whether adding fiber to metformin helps teens with severe obesity and insulin resistance improve how their bodies handle sugar. You might consider it if you’re a teen who isn’t yet diagnosed with type 2 diabetes and meets the specific lab and health criteria.
Edmonton, AlbertaAges 12–18 - NCT05982847Recruiting
Blood pressure check for kids in South Africa
This study checks blood pressure in children ages 5 to 17 across South Africa. It aims to find normal blood pressure ranges and improve healthcare for kids.
Mthatha, Eastern CapeAges 5–18 - NCT05975541Recruiting
Infection risk in obesity and type 2 diabetes
This study looks at how obesity and type 2 diabetes affect your body's ability to fight infections. By joining, you'll help researchers understand why some people with these conditions get more infections, which could lead to better prevention and treatment.
Novara, NovaraAges 18–65 - NCT05987410Recruiting
Nordic walking for weight and heart health after a cardiac event
This trial tests if a nordic walking program helps people with diabetes who are overweight or obese recover after a heart attack or heart procedure. If you had a heart event or stent/bypass in the last 3 months, this program could help you get stronger and manage your weight.
MilanAges 18 years+ - NCT05945355Recruiting
Study of breathing training for children with asthma
This study looks at how an asthma-specific breathing training program affects children’s breathing and asthma control. It may help your care team understand who could benefit from inspiratory (breathing-in) training.
Durham, North CarolinaAges 6–17 - NCT05962372Recruiting
Culturally tailored diet program for adults in Puerto Rico
This study tests a diet program designed to fit Puerto Rico culture and daily life. It may help adults with weight or blood sugar or blood fat concerns improve their health through regular check-ins.
San JuanAges 30–65 - NCT05918575Recruiting
Breathing support after a breathing tube in very obese adults
This trial tests whether giving noninvasive breathing support (using a mask or similar device, without a new breathing tube) right after removing a breathing tube works better for severely obese adults. It mainly looks at people at higher risk of needing help breathing again after extubation.
Chicago, IllinoisAges 18 years+ - NCT05933499RecruitingPhase 2
Tirzepatide and bimagrumab for body fat and insulin sensitivity
This Phase 2 study tests two medicines to see how they change body fat, insulin sensitivity, and bone health in adults with obesity. It may help people who have tried lifestyle changes to lose weight but have not been able to, though diabetes and several health conditions must be ruled out first.
Boston, MassachusettsAges 18 years+ - NCT05906238Recruiting
Study to reduce harm from obesity stigma
This trial looks at ways to lessen the negative effects that people may experience from weight-related stigma. It’s meant to help improve well-being for people living with obesity.
Poitiers, VienneAges 18 years+
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Common questions
- Are there clinical trials for obesity?
- Yes. Clin2 currently lists 1,434 recruiting obesity studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a obesity trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a obesity trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.