Clinical trials
Obesity clinical trials
Excess body weight that increases the risk of many other health conditions. We’re tracking 1,500 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT07437430Recruiting
Study on food additives and weight in adults with obesity
This study looks at how certain food additives might affect weight. If you have obesity, you may be able to join to help understand how these additives play a role.
Hamilton, OntarioAges 20–80 - NCT07441252RecruitingPhase 2
Study of maridebart cafraglutide for fatty liver with obesity
This trial tests a new medication (maridebart cafraglutide) to see if it can reduce fat in the liver and help with weight loss. It may be an option for adults with excess liver fat and obesity or overweight who haven't been able to lose weight with diet and exercise alone.
Chandler, ArizonaAges 18–99 - NCT07443956Recruiting
Biologic and anti-obesity drug combo for psoriatic arthritis
This study tests whether adding a weight-loss medication (tirzepatide) to a biologic (ixekizumab) helps people with psoriatic arthritis and overweight or obesity. You will need to have biopsies of joint tissue and fat to see how the treatment affects inflammation.
Birmingham, EnglandAges 18–75 - NCT07445503Recruiting
High phenolic olive oil for metabolic health in central obesity
This trial tests whether a special olive oil rich in natural plant compounds (polyphenols) can improve metabolic health in people with belly fat. You may be eligible if you are an adult with overweight or obesity and have at least one related health issue like high blood pressure, high blood sugar, or abnormal cholesterol.
KalamataAges 18–80 - NCT07447440Recruiting
Study on natural fats linked to obesity-related diseases
This trial explores how certain natural fats in the body might affect diseases linked to obesity, such as breast cancer. It aims to see if these fats can reduce inflammation and improve health.
Pamplona, NavarreAges Any age - NCT07463846RecruitingPhase 1/Phase 2
Study of ALN-2232 in people with obesity
This trial tests an investigational drug called ALN-2232 in people with obesity to see if it can help with weight management. You may be able to join if you have a BMI between 30 and 40 and do not have diabetes or take other weight-loss or diabetes medications.
Mount RoyalAges 18–65 - NCT07464015Recruiting
Summer day camps for childhood obesity
This trial is testing whether sending kids to summer day camps can help them manage their weight. It's for children from low-income families who are overweight or obese and see a pediatric doctor.
Orlando, FloridaAges 5–11 - NCT07465965RecruitingPhase 1
Weight loss study of semaglutide nasal spray in overweight or obese adults
This study tests a nasal spray containing semaglutide (a GLP-1 receptor agonist) to see if it helps adults who are overweight or obese lose weight. It may be an option if you have a BMI between 27 and 35 and have not used other weight loss medications recently.
Secaucus, New JerseyAges 18–65 - NCT07466069Recruiting
Healthy lifestyle program for transgender teens
This trial tests a lifestyle program designed to prevent obesity and eating disorders in transgender and gender-diverse adolescents. It aims to support healthy habits and well-being during a critical developmental stage.
São Paulo, São PauloAges 10–14 - NCT07467447RecruitingPhase 2
Testing a weight-loss drug for people with obesity or overweight
This trial tests whether an experimental drug (LY3437943) can help people with obesity or overweight lose weight. It compares the drug to a placebo (inactive shot), and you must be willing to give yourself daily injections.
Shenzhen, GuangdongAges 18–75 - NCT07467694Recruiting
Postnatal exercise to activate baby's brown fat
This trial tests if exercise after childbirth can activate your baby's brown fat, which helps with metabolism. It may benefit mothers and their healthy, full-term babies.
Boston, MassachusettsAges 18–45 - NCT07472881Recruiting
Laser therapy for body shape in obese menopausal women
This study tests whether a laser therapy applied to specific points on the body can help with weight and body shape in women going through menopause who are overweight. It aims to find a safe, non-invasive option for weight management.
Keelung, TaiwanAges 45–55 - NCT07481747RecruitingPhase 3
Weekly injection for weight loss in adults with obesity
This trial tests a once-weekly injection (tirzepatide) versus a placebo to help people who are obese or overweight with related health conditions lose weight. You may qualify if you have tried to lose weight through diet before, but have not been successful.
Shenzhen, GuangdongAges 18 years+ - NCT07482436Recruiting
Airway ultrasound vs laryngoscopy in obesity
This study compares two ways of checking the airway before surgery in people with obesity: a breathing tube placed with the help of ultrasound (a handheld device that uses sound waves) versus a standard laryngoscope (a lighted tool). The goal is to see which method is safer and easier for larger patients.
TrabzonAges 18 years+ - NCT06396416RecruitingPhase 4
Obesity management after kidney transplant
This study tests whether a weight loss medication (semaglutide) can help manage obesity in people who have had a kidney transplant or are at high risk. It aims to improve health outcomes and prevent further kidney decline.
London, OntarioAges 18 years+ - NCT07331974Recruiting
A trial of Akkermansia for weight loss in overweight adults
This trial tests a supplement containing Akkermansia bacteria to see if it helps adults who are overweight or obese lose weight. It may be an option if you have not taken weight loss medications recently and are already trying to manage your weight with diet and exercise.
Guangzhou, GuangdongAges 18–60 - NCT07624071RecruitingPhase 1
Testing ALN-6222 for weight management in adults
This Phase 1 trial tests a new medicine called ALN-6222 in people with obesity to see if it's safe and how well it works. The study focuses on adults with a BMI between 30 and 40 who don't have diabetes.
Mount RoyalAges 18–65 - NCT07487376RecruitingPhase 1
A single-dose study of IBIO-600 in healthy overweight or obese adults
This trial tests a single dose of an experimental treatment called IBIO-600 to see if it's safe and how it works in overweight or obese adults. It's for people who are generally healthy and have a stable weight, without diabetes.
Bayswater, VictoriaAges 18–65 - NCT07495904Recruiting
Weight loss drug effects on body muscle with extra protein
This trial tests a weight-loss medication (GLP-1 receptor agonist) combined with dietary protein to see if it helps protect muscle while losing fat. It is for adults with obesity who are not taking certain other medications or supplements.
HeraklionAges 30–65 - NCT07501377Recruiting
Diet and brain health study for women in menopause with overweight
This trial tests whether a diet rich in fiber and plant compounds (polyphenols) can reduce brain inflammation in perimenopausal women who are overweight. If you're in early menopause and have some inflammation, this study may show how diet affects your brain health.
Leipzig, SaxonyAges 35–60 - NCT07508020RecruitingPhase 1
How a new medicine affects appetite and metabolism in people with obesity
This study tests an experimental drug (NNC0487-0111) to see how it changes food intake, appetite, and the way your body processes food after meals. It is for adults with obesity who do not have diabetes.
BerlinAges 18–64 - NCT07511205RecruitingPhase 1
Study of AZD1043 for overweight or obesity
This trial tests a new medicine called AZD1043 in healthy adults who are overweight or have obesity. It aims to see if the medicine is safe and how the body handles it.
Glendale, CaliforniaAges 18–65 - NCT07513168RecruitingPhase 4
Low-dose semaglutide for weight loss in obese adults
This study tests whether a low dose of semaglutide (a once-weekly injection) can help obese adults without diabetes lose weight. Semaglutide works by reducing appetite and helping your body use food differently.
Hyderābād, SindhAges 18 years+ - NCT07514611Recruiting
Weight Loss Guidance for Heart Disease and Obesity
This trial tests whether using a smartphone app to guide weight loss helps people with coronary heart disease (a condition where blood vessels to the heart are narrowed) and obesity lose weight safely. The goal is to see if this personalized digital guidance can improve your health outcomes.
Guangzhou, GuangdongAges 18–65
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Common questions
- Are there clinical trials for obesity?
- Yes. Clin2 currently lists 1,500 recruiting obesity studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a obesity trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a obesity trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.