Clinical trials
Obesity clinical trials
Excess body weight that increases the risk of many other health conditions. We’re tracking 1,500 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT07515547Recruiting
How Obesity Affects the Body Over Time
This research study examines how excess weight impacts your body's health and function, both in the short term and long term. Researchers want to understand the physical changes that happen with obesity and how your body responds.
Montreal, QuebecAges 25–40 - NCT07521631RecruitingPhase 2
HDM1005 versus Tirzepatide for weight management in obese adults
This study tests whether a new injectable medication called HDM1005 works as well as tirzepatide (a GLP-1 drug) for weight loss in adults with obesity but no diabetes. Both medications work similarly in the body to help control appetite and weight.
ShanghaiAges 18–65 - NCT07528027RecruitingPhase 3
Testing HRS-7535 for High Blood Pressure and Extra Weight
This study tests whether a new medicine called HRS-7535 can help lower blood pressure in people who are overweight or have obesity. You would take it alongside your current blood pressure medications (or as a new treatment) to see if it works better at controlling your blood pressure.
Beijing, Beijing MunicipalityAges 18–70 - NCT07536256Recruiting
Youth Resilience Through Native Hawaiian Culture in Wai'anae
This program connects young people in the Wai'anae community with culturally rooted activities and support to build resilience and improve physical and mental health. You'll work with other youth and community organizations that use Native Hawaiian values to help you thrive.
Waianae, HawaiiAges 12–25 - NCT07540949Recruiting
Lemon Fermented Product for Weight and Metabolism in Adults
This study tests whether a lemon fermented product supplement can help improve metabolism and metabolic health in adults with obesity. Participants will take capsules and have their metabolism and health markers measured over time.
TaoyuanAges 18–65 - NCT07541677Recruiting
Muscle Loss and Obesity: Understanding Risk Factors
This study examines how muscle loss (sarcopenia) relates to obesity in adults seeking weight-loss treatment. Researchers will assess your muscle strength and physical function to identify risk factors, which could help improve future obesity care.
SingaporeAges 21–100 - NCT07550816RecruitingPhase 1
Safety study of ZT002 injection in overweight adults
This study tests how a new diabetes medicine called ZT002 works in the body and whether it interacts safely with other common medications. Researchers will monitor healthy volunteers who are overweight to understand the medicine's safety and effectiveness.
Chengdu, SichuanAges 18–45 - NCT07557953RecruitingPhase 1
How cagrilintide affects hunger and eating in overweight adults
This early-stage study tests a new medication called cagrilintide to see how it influences appetite and food intake in adults with overweight or obesity. Researchers want to understand if this drug could help people feel fuller and eat less.
BerlinAges 18–64 - NCT07559227Recruiting
How obesity affects gut health and blood vessel function
This study compares people with normal weight to people with obesity who are otherwise healthy to understand how body weight affects gut bacteria, immune function, and blood vessel health. Results may help explain why some people with obesity stay healthier than others.
Muncie, IndianaAges 18–55 - NCT07564414RecruitingPhase 3
Weight Loss Study Comparing Two Doses of CagriSema
This study tests whether a new combination medication called CagriSema (in two different doses) helps people with obesity lose weight. You may qualify if you're 18 or older, have a BMI of 35 or higher, and either don't have type 2 diabetes or have it well-controlled.
Birmingham, AlabamaAges 18 years+ - NCT07570758RecruitingPhase 2
Testing ERX1000 to Help Adults Manage Obesity
This study tests whether a new medication called ERX1000 is safe and well-tolerated in adults with obesity. The trial will help doctors understand if this treatment could be helpful for weight management.
Louisville, KentuckyAges 18–60 - NCT07576478Recruiting
Balloon Blowing Therapy for Obese Children
This trial tests whether blowing up balloons can help obese children breathe easier and feel better. The study measures changes in breathing, shortness of breath, and quality of life over the course of the treatment.
Peshawar, Khyber PakhtunkhwaAges 6–12 - NCT07589608RecruitingPhase 2
Weight Loss Study With Two New Injectable Medications
This study tests two new injectable drugs (macupatide and eloralintide) alone or together to help adults with obesity or excess weight lose weight. The goal is to see if these medications are safe and effective for weight management.
Chandler, ArizonaAges 18–75 - NCT07597018RecruitingPhase 1
Comparing Blood Levels of Cagrilintide Versions in Adults With Overweight
This early-stage study tests different formulations of cagrilintide, a new medication, to see how the body absorbs and processes each version. Cagrilintide may help with weight management. Researchers will measure blood levels after you receive multiple doses.
BerlinAges 18–64 - NCT07611240Recruiting
Comparing two anesthesia types for spine surgery in overweight patients
This study compares two common anesthesia medicines—sevoflurane (inhaled gas) and propofol (IV liquid)—to see which works better for people with obesity having lower-back spine surgery. The goal is to understand which anesthetic is safer and more effective for this group.
ErzurumAges 18–65 - NCT07618741Recruiting
Improving AF Ablation Outcomes in Patients with Obesity
This study tests whether special care strategies can help obese patients have better results after a catheter ablation procedure for atrial fibrillation (a heart rhythm problem). Catheter ablation uses heat or cold to fix the irregular heartbeats.
TaipeiAges 20 years+ - NCT07627919Recruiting
Strength training and high-protein diet for frail older women
This study tests whether combining resistance exercises with a protein-rich diet can improve muscle strength and overall function in older women with weak muscles. You would attend supervised workouts and follow a specific eating plan for several weeks.
El-Sheikh Zayed CityAges 60–70 - NCT07633639Recruiting
GLP-1 Medicine After Weight-Loss Surgery in Chinese Patients
This trial tests whether adding a GLP-1 medication (a type of diabetes and weight-loss drug) after weight-loss surgery helps patients with obesity and related health conditions like diabetes. Researchers want to see if combining surgery with this medicine works better than surgery alone.
BeijingAges 18–60 - NCT07641361Recruiting
Staying Hydrated to Feel Better on GLP-1 Medication
This study tests whether drinking more water helps reduce uncomfortable side effects (like nausea and vomiting) when you first start taking GLP-1 medications for weight loss or diabetes. You'll be asked to follow a hydration plan and report how you feel.
Buffalo, New YorkAges 18–60 - NCT07652333Recruiting
Strength training for muscle and mind on obesity medication
This study tests whether strength training can help adults taking new obesity medications (like Wegovy or Ozempic) maintain muscle and improve mental health. You would start the medication after your first study visit.
Pittsburgh, PennsylvaniaAges 18 years+ - NCT07654439Recruiting
Mixed reality tests for overweight and obese adults
This trial tests if mixed reality (combining real and virtual worlds) performance tests are valid and reliable for overweight and obese adults. You may be able to help researchers improve these tests if you are overweight or obese.
Konya, SelcukluAges 18–65 - NCT07656727RecruitingPhase 2
A study of BGE-102 for obesity and heart risk
This trial tests an experimental drug called BGE-102 in people with obesity and signs of inflammation. It aims to see if the drug can help reduce body weight and improve heart health. Participants must be willing to keep a stable diet and exercise routine.
Chandler, ArizonaAges 18 years+ - NCT07658755Recruiting
LiverSeek: Finding advanced liver scarring in MASLD
This study uses routine blood tests to find people with advanced liver scarring caused by a condition called MASLD. If you are between 50 and 75, have certain metabolic risks, and get blood work from your primary care doctor at select centers, you may be eligible.
Madrid, MadridAges 50–75 - NCT07662330Recruiting
Spermidine for weight and cholesterol in overweight adults
This trial tests if a natural supplement called spermidine can help lower cholesterol and body weight in overweight people with high cholesterol. You cannot be on any cholesterol or diabetes medications.
Shanghai, Shanghai MunicipalityAges 18–60
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Common questions
- Are there clinical trials for obesity?
- Yes. Clin2 currently lists 1,500 recruiting obesity studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a obesity trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a obesity trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.