Clinical trials
Obesity clinical trials
Excess body weight that increases the risk of many other health conditions. We’re tracking 1,434 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT05077579Recruiting
Alzheimer’s scan study for people with higher body weight
This study uses brain scans (MRI and two special PET scans) to see how Alzheimer’s-related changes show up in people who are overweight or obese, with different blood-sugar and insulin patterns. It may help researchers understand whether body weight and metabolism affect early Alzheimer’s markers in the brain.
St Louis, MissouriAges 40–60 - NCT05080699Enrolling by invitation
Peptide-based diet study for adults on home tube feeding
This study tests whether a special “peptide-based” diet helps people with obesity who rely on home tube feeding after a stroke. It aims to see if this diet is safe and beneficial for weight and overall health while you stay on the nutrition you need.
Rochester, MinnesotaAges 18 years+ - NCT05125822Recruiting
Study of how bodies change weight in youth with obesity
This study looks at what helps or drives weight changes in children and teens with obesity. You may be asked about growth and body changes to better understand why weight changes happen and how to manage them.
Chicago, IllinoisAges 11–15 - NCT05028309Recruiting
Study how obesity affects breathing and exercise in older adults
This study compares how body weight (higher or lower body fat) affects lung function, breathing during exercise, and exercise capacity in adults ages 65–75. You may be asked to do lung and exercise testing, but only if you meet health and activity restrictions.
Dallas, TexasAges 65–75 - NCT05028205Recruiting
Fruit and vegetable voucher program for kids
This trial tests whether giving families vouchers for fruits and vegetables helps improve children’s eating and health. It focuses on children ages 4–10 who have higher body weight for their age and who can participate with an adult caregiver.
Knoxville, TennesseeAges 4–10 - NCT04873258Recruiting
Test a non-invasive tool to screen for fat-related liver disease
This study looks at a new non-invasive screening method to predict metabolic dysfunction–associated steatotic liver disease (MASLD), a condition where fat builds up in the liver. The goal is to help identify people who may be at risk without needing invasive tests.
London, LondonAges 18–80 - NCT04883515Recruiting
Glutamine drink for insulin resistance and bowel symptoms
This trial studies whether taking an oral glutamine supplement can improve insulin resistance and reduce bowel-related problems in people with obesity and irritable bowel syndrome. It may help your blood sugar regulation and digestive comfort if you meet the criteria.
RouenAges 18–65 - NCT03756961Recruiting
Opioid-free care plan for people having weight-loss surgery
This trial studies whether an opioid-free or opioid-sparing care pathway can improve comfort and outcomes for adults undergoing laparoscopic weight-loss surgery. It may help people avoid side effects from opioid pain medicines while still managing pain safely.
Lindesberg, Region ÖrebroAges 18 years+ - NCT04839614Recruiting
Weight-loss surgery plus uterus surgery for certain uterine lining conditions
This trial tests doing weight-loss surgery at the same time as laparoscopic uterus (womb) surgery for people with certain early uterine lining conditions. It may help lower risk from severe obesity while treating the uterine condition.
Boston, MassachusettsAges 18 years+ - NCT04805502Recruiting
Pregnancy exercise program to help prevent childhood obesity
This trial studies whether a structured exercise program during pregnancy can help lower the risk of childhood obesity. If you qualify, you may be asked to exercise during early pregnancy and share information with the research team.
Greenville, North CarolinaAges 18–45 - NCT04838678RecruitingEarly Phase 1
Testing a new blood-pressure approach in obesity-related hypertension
This early-stage study tests a new way to help control high blood pressure that is linked to obesity. It may help people whose blood pressure is high based on a 24-hour blood pressure monitor.
Dallas, TexasAges 18–55 - NCT04714892Recruiting
Taste and smell differences in obesity
This study looks at how taste and smell may differ in people with obesity compared to healthy-weight individuals. It aims to understand why some people perceive flavors differently, which could help develop better treatments for weight management.
Bethesda, MarylandAges 18–65 - NCT04748770Recruiting
Kidney Transplant Access for Obese Dialysis Patients
This study looks at whether obese patients who are starting dialysis can safely receive kidney transplants. Researchers want to understand how weight affects transplant success and access to this life-changing treatment.
AmiensAges 18 years+ - NCT04613791Recruiting
Alcohol and addictive behaviors in people with obesity
This study looks at how often people with obesity struggle with alcohol or other addictive behaviors, and how these issues change over time. Understanding this connection may help doctors better support patients managing obesity.
NîmesAges 18 years+ - NCT04232566Recruiting
Study links in obesity surgery and liver scarring
This study looks at how the immune system relates to liver scarring in people with obesity who are getting gastric bypass surgery. If you qualify, you may help doctors better understand liver disease and who is at higher risk.
Scottsdale, ArizonaAges 30–70 - NCT04003038Recruiting
Negative pressure wound dressings after breast reconstruction in obesity
This trial tests whether a special “suction” dressing (negative pressure wound therapy) helps wounds heal better after breast reconstruction using tissue from the belly, especially in people with higher body weight. You may be more likely to benefit if you’re at higher risk for wound problems after abdominal flap surgery.
Houston, TexasAges 18 years+ - NCT03880422Recruiting
Exercise and nutrition for weight and frailty after prostate cancer treatment
This study tests whether a structured exercise and nutrition program can improve obesity-related frailty and overall function in people with advanced prostate cancer who are taking hormone therapy (ADT). It may help with strength, mobility, and healthier body weight during/after ADT.
Buffalo, New YorkAges 18 years+ - NCT03514602Recruiting
Help quitting smoking to prevent childhood obesity
This study supports pregnant people who smoke to quit or cut down, using behavior-based coaching. It also measures how changes in smoking may help lower a child’s risk of developing obesity.
Buffalo, New YorkAges 18–39 - NCT03472157Recruiting
Bariatric surgery for severe NASH with advanced liver scarring
This study tests whether bariatric surgery (either sleeve gastrectomy or Roux-en-Y gastric bypass) improves severe nonalcoholic steatohepatitis (NASH) with advanced liver scarring in people who are obese. You may also need liver biopsies to confirm your liver disease before and after treatment.
LilleAges 18–65 - NCT03288207Recruiting
Mobile app for heart health in African American women
This study tests a mobile health app to help African American women with overweight or obesity in specific DC and Maryland neighborhoods improve their heart health. Participants will use the app and wear a wrist device to track activity, with the goal of reducing heart disease risk.
Bethesda, MarylandAges 21–75 - NCT03135730Recruiting
ROHHAD patient registry for rapid-onset obesity
This study is a registry that collects information from people diagnosed with, or suspected to have, ROHHAD. It can help researchers better understand the condition over time and improve future care.
Chicago, IllinoisAges Any age - NCT03296605Enrolling by invitation
Study of obesity treatment after bariatric or belly surgery
This trial looks at obesity care in people who have already had bariatric (weight-loss) surgery or certain abdominal surgery. It may help researchers understand what treatments or follow-up care could work best for you after surgery.
Nanjing, JiangsuAges 18–75 - NCT03022682Recruiting
Study of inflammation and metabolism across diabetes and weight
This is an observational study that follows generally healthy adults to understand how inflammation, diabetes (type 2), and weight/metabolic health relate to each other. It may help researchers figure out why different groups (including different ethnic backgrounds) have different health risks.
San Francisco, CaliforniaAges 18–75 - NCT02674230Recruiting
Obesity and body clock registry for healthy aging
This study is a registry that collects health information to better understand how weight and your body’s daily rhythm may affect healthy aging. It may help researchers identify patterns linked to aging and future health risks.
TaoyuanAges 20 years+
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Common questions
- Are there clinical trials for obesity?
- Yes. Clin2 currently lists 1,434 recruiting obesity studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a obesity trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a obesity trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.