Clinical trials
Obstructive Sleep Apnea clinical trials
Below are recruiting obstructive sleep apnea clinical trials, each written for real people, not researchers. We’re tracking 299 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT06261034Recruiting
How sex affects blood pressure control
This study looks at how the nervous system controls blood pressure differently in men and women. It may help researchers understand why some heart conditions affect men and women differently.
Rochester, MinnesotaAges 20–70 - NCT06227572Recruiting
Thinking and memory after sleep apnea treatment in Native Americans
This study looks at whether using a PAP (breathing) machine helps thinking and memory in Native American adults with sleep apnea. If you are 50 or older and just starting PAP therapy, researchers want to see how it affects your brain health.
Eagle Butte, South DakotaAges 40 years+ - NCT06132477RecruitingPhase 4
Study of GLP-1 medicines after weight loss surgery
This study looks at what happens when people taking a GLP-1 medication (like Ozempic) either stop or continue it after weight loss surgery. The goal is to learn whether staying on the medicine helps with long-term weight control.
Columbia, MissouriAges 18 years+ - NCT06047353Recruiting
Helping people with sleep apnea try PAP therapy for the first time
This study tests whether health advocates can help people with moderate-to-severe sleep apnea start using a PAP machine. If you've never used a PAP or other sleep apnea treatment before, this trial may help you get support and guidance.
Miami, FloridaAges 18–100 - NCT04557293Recruiting
Testing how thinking decisions affect CPAP use
This trial studies whether a person’s decision-making skills affect how well they use CPAP, a common treatment for sleep apnea. It may help you and your care team improve CPAP adherence so therapy is more effective.
PaviaAges 18–80 - NCT05988385Recruiting
Treating sleep apnea to protect memory in older adults
This study tests whether treating sleep apnea can help protect memory and brain health in older adults. It involves using a CPAP machine or other treatments for sleep apnea and may include memory tests and brain scans over 2 years.
Tucson, ArizonaAges 55–85 - NCT05917119Recruiting
Bright light therapy for obstructive sleep apnea symptoms
This study tests whether a “bright light” treatment can reduce daytime sleepiness in people with obstructive sleep apnea who are already using CPAP or BiPAP. It may help people feel more awake during the day without changing their sleep apnea device use.
Pittsburgh, PennsylvaniaAges 40–65 - NCT05838183Recruiting
Test treatment in people with lung disease and sleep apnea
This trial is studying how a treatment may work for adults who have interstitial lung disease or obstructive sleep apnea. It likely involves sleep testing so the team can measure breathing and sleep patterns.
TianjinAges 18–80 - NCT05606991Enrolling by invitation
Testing how CPAP affects brain waste clearance during sleep
This study looks at how stopping CPAP for 14 nights affects “brain waste clearance,” a process your brain uses to clear byproducts during sleep. It is testing whether using CPAP versus stopping it changes this brain cleanup in adults with severe obstructive sleep apnea (OSA).
Macquarie Park, New South WalesAges 35–65 - NCT05501236Recruiting
Nerve stimulation for sleep apnea using neck nerve signals
This study tests a device that stimulates nerves in the neck to help keep your airway open during sleep for obstructive sleep apnea. If you fit the safety and sleep-study requirements, it may offer an alternative approach to improving breathing at night.
Nashville, TennesseeAges 18 years+ - NCT05429983Recruiting
Predicts results from Inspire tongue-stimulation for sleep apnea
This study looks at how breathing mechanics during a sleep-related test (DISE) can help predict how well Inspire tongue (hypoglossal nerve) stimulation will work. It may help your care team choose the best approach and set expectations for improvement.
Baltimore, MarylandAges 18 years+ - NCT05350215RecruitingPhase 1/Phase 2
Testing atomoxetine and DAW2022 for obstructive sleep apnea severity
This study tests whether atomoxetine and DAW2022 can improve how severe obstructive sleep apnea is. It may help by changing breathing patterns during sleep, measured through physiology tests.
Boston, MassachusettsAges 21–70 - NCT05293600RecruitingPhase 1/Phase 2
Rescue medicine trial for sleep apnea after other treatments fail
This trial studies a “rescue” set of medicines for obstructive sleep apnea when two common treatments haven’t worked well enough. If you still have frequent breathing pauses during sleep, the study may test whether these medicines can reduce them and improve safety and symptoms.
Boston, MassachusettsAges 21–70 - NCT05262439Recruiting
Follow-up study of CPAP mask systems for sleep apnea
This study checks how ResMed CPAP mask systems work in real-life use for people with obstructive sleep apnea (OSA). It may help improve comfort, fit, and performance based on what patients experience over time.
Sydney, New South WalesAges 18–100 - NCT05156112Recruiting
Sleep apnea treatment for veterans with PTSD and substance use
This study tests whether treating sleep apnea with a breathing device during a residential program helps veterans with post-traumatic stress disorder (PTSD) and substance use problems. It aims to improve their recovery and quality of life.
San Diego, CaliforniaAges 18 years+ - NCT04630535Recruiting
Using brief arm treatment before bypass surgery
This trial studies whether a simple, remote “arm treatment” given before scheduled aorto-bifemoral bypass surgery can help protect blood flow during surgery. If you fit the surgery plan and don’t have certain excluded conditions, the study may offer an added protective approach.
Brno, Czech RepublicAges 18 years+ - NCT04538755Enrolling by invitationPhase 1/Phase 2
Testing a new drug for moderate to severe sleep apnea
This trial tests a drug called DAW2020 to see if it can improve how your body controls breathing during sleep. You may qualify if you have moderate to severe sleep apnea and are otherwise healthy.
Boston, MassachusettsAges 21–70 - NCT04191512Recruiting
Comparing two treatments for sleep apnea
This study compares two common treatments for moderate to severe sleep apnea: a device that keeps your airway open during sleep and a machine that delivers air pressure. It aims to see which works better for people like you.
Philadelphia, PennsylvaniaAges 22 years+ - NCT04129229Enrolling by invitation
Tongue device study for moderate-to-severe sleep apnea and snoring
This trial tests a tongue retractor device to help treat obstructive sleep apnea and reduce snoring in adults. You may be eligible if you have moderate-to-severe sleep apnea and can avoid other common treatments during the study.
Brighton, MassachusettsAges 18 years+ - NCT03725956Recruiting
Sleep study before and after nasal polyp surgery
This study uses a sleep test to look at breathing and sleep patterns in people with nasal polyps who need surgery because medicine didn’t help. It may help doctors understand how nasal polyps affect sleep and how surgery changes those sleep measurements.
LilleAges 18 years+ - NCT03589846Enrolling by invitation
Muscle stimulation during a sleep endoscopy test
This trial studies whether muscle stimulation during DISE (a procedure to look at your airway while you’re sedated) can help people with obstructive sleep apnea who can’t tolerate CPAP. Your DISE is part of routine care, and the study adds a muscle stimulation step to see if it changes what’s happening in the throat.
Nashvile, TennesseeAges 18 years+ - NCT07775976Enrolling by invitation
Whole-heart checkup with a wearable heart monitor
This study looks at how well a wearable heart monitor and special software can check the health of your whole heart and assess your risk of future heart problems. It may help doctors create more personalized care plans.
Pasadena, CaliforniaAges 18 years+ - NCT02922894RecruitingPhase 4
Testing sleep apnea care in people with spinal cord injury
This study looks at treatment for sleep apnea (breathing pauses during sleep) in adults with a spinal cord injury. If you qualify, the trial team may help manage sleep-related breathing problems and track how well the treatment works.
Detroit, MichiganAges 18–89 - NCT02057783Recruiting
Exercise program to lower blood pressure in sleep apnea
This trial tests whether a supervised physical activity program can help lower blood pressure in people with obstructive sleep apnea and resistant high blood pressure. It may help you control blood pressure when it has not improved despite multiple medications.
QuébecAges 18–80
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Common questions
- Are there clinical trials for obstructive sleep apnea?
- Yes. Clin2 currently lists 299 recruiting obstructive sleep apnea studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a obstructive sleep apnea trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a obstructive sleep apnea trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.