Clinical trials
Overweight or Obese Adults clinical trials
Below are recruiting overweight or obese adults clinical trials, each written for real people, not researchers. We’re tracking 808 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT06455878Recruiting
Mobile app for weight loss in heart failure patients
This trial tests a mobile app that helps you track your diet to manage your weight. It is designed for people with heart failure who are overweight and have recently been in the hospital for their condition.
Beijing, Beijing MunicipalityAges 18 years+ - NCT06545435Recruiting
Study on body composition using BIA in adults with obesity
This trial uses a simple test called bioelectrical impedance analysis (BIA) to estimate muscle and fat in adults with obesity, comparing it to a more precise scan (DXA). It aims to see if BIA can reliably measure body composition.
Baton Rouge, LouisianaAges 18 years+ - NCT06557317Recruiting
Lifestyle program for Black teen girls at risk for type 2 diabetes
This study tests if an in-person lifestyle program can help prevent type 2 diabetes in Black adolescent girls who have obesity. The program involves both the teen and a caregiver who prepares most of the household meals.
Brooklyn, New YorkAges 12–18 - NCT06937203RecruitingPhase 1/Phase 2
A new obesity drug study for people with or without type 2 diabetes
This early-stage study tests an investigational drug called ARO-ALK7 to see if it helps adults with obesity lose weight. It includes people who have type 2 diabetes as well as those who do not, and requires that you have tried to lose weight with lifestyle changes in the past.
Morayfield, QLCAges 18–65 - NCT07690163Recruiting
Diabetes blood sugar check in newly diagnosed patients
This trial is checking how well blood sugar is controlled in adults recently diagnosed with type 2 diabetes (within the last 3 months). It aims to see if current treatments or lifestyle changes are working and may help guide future care.
KyivAges 18 years+ - NCT06645470Recruiting
Muscle and movement study for weight loss medications
This study looks at how anti-obesity medications like semaglutide (Ozempic, Wegovy) and tirzepatide (Mounjaro, Zepbound) affect your muscles and movement. It may help researchers understand how to combine these drugs with exercise for better health.
Kansas City, KansasAges 18 years+ - NCT06720246Recruiting
Weight loss surgery and liraglutide study on thinking and long-term weight
This trial tests whether bariatric surgery or the drug liraglutide helps people with obesity lose weight and keep it off by looking at how it affects your thinking and behavior. It might help you understand which treatment works best for long-term success.
Milan, MilanAges 20–60 - NCT06735599Recruiting
Wild blueberries for blood pressure health
This study tests whether eating wild blueberries can improve your gut, brain, and heart health if you have high blood pressure. You'll eat blueberries daily for several weeks and have checkups to see how your body responds.
Atlanta, GeorgiaAges 45–65 - NCT06739473RecruitingPhase 4
How obesity affects glucose use in the body
This trial looks at how the body uses sugar (glucose) for energy in people with and without obesity. Results could help find better treatments for metabolic conditions.
TurkuAges 20–60 - NCT06786052RecruitingPhase 2
Study on after-meal energy in adults 50–70
This trial studies how a probiotic supplement affects energy use after meals in adults aged 50–70 who are overweight. You'll take either the probiotic or a placebo for several weeks.
Pierre-Bénite, Auvergne-Rhône-AlpesAges 50–70 - NCT06790160Recruiting
Study of weight-loss medication effects on body composition
This trial looks at how two weight-loss medications, semaglutide and tirzepatide, affect your body's fat and muscle. It may help you understand if these medications improve your overall health beyond just weight loss.
Lubbock, TexasAges 18 years+ - NCT06809166RecruitingPhase 4
Contrave for weight loss in adults with obesity
This study tests whether a weight loss medication called Contrave can help adults with obesity lose weight by changing how their body uses energy and handles food. If you qualify, you will take Contrave and be monitored for several months.
Ottawa, OntarioAges 18–64 - NCT06811324RecruitingPhase 2
Tirzepatide for muscle and vessel health in older adults
This study tests if the drug tirzepatide can improve muscle and blood vessel health in older adults with obesity. You may be eligible if you are 50 or older, have a BMI between 30 and 40, and do not have diabetes.
San Antonio, TexasAges 50 years+ - NCT06817863RecruitingPhase 1/Phase 2
Mobile app for binge eating and weight loss
This study tests a self-guided mobile app (iPhone or Android) to help adults with binge eating and obesity. It aims to see if the app can reduce binge eating episodes and support weight management.
Philadelphia, PennsylvaniaAges 18–70 - NCT06820099RecruitingPhase 2
A drug for heart failure with obesity
This trial tests an oral drug called HRS-7535 for people with a certain type of heart failure (where the heart pumps normally but doesn't relax properly) and who also have obesity. It aims to see if the drug can improve symptoms and daily function.
Beijing, Beijing MunicipalityAges 18–80 - NCT06861868Recruiting
Brain and behavior's role in childhood obesity
This study looks at how the brain and behavior contribute to obesity from infancy through childhood. It may help researchers understand why some children develop obesity and how to prevent it.
Baltimore, MarylandAges 7–12 - NCT06886126RecruitingPhase 2
Testing HDM1005 injection for weight loss in adults with obesity
This study tests an experimental injection called HDM1005 for adults with obesity who do not have diabetes. The goal is to see if it helps with weight loss when combined with diet and exercise.
NanjingAges 18–65 - NCT06937060RecruitingPhase 3
Semaglutide for psoriasis and obesity
This trial tests if semaglutide, a medicine used for diabetes and weight loss, can help people with both psoriasis and obesity. You may qualify if you have moderate to severe psoriasis, a high body weight, and are of Chinese descent.
Hong KongAges 18–75 - NCT06991296Recruiting
Omega-3 supplement study for adults with obesity
This study looks at how omega-3 supplements affect certain fats in the blood of adults with obesity. Researchers want to see if taking these supplements changes these fats in a helpful way.
Kannapolis, North CarolinaAges 45–60 - NCT07032545Recruiting
Broccoli microgreens study for obese breast cancer survivors
This trial tests if eating broccoli microgreens can improve metabolism in obese breast cancer survivors. Participants will avoid other cruciferous vegetables during the study to see how the microgreens affect their health.
Baltimore, MarylandAges Any age - NCT07073781Recruiting
Probiotics for Brain & Blood Sugar in Overweight Young Adults
This study tests whether taking a probiotic (a 'good bacteria' supplement) can help brain function (thinking, memory) and improve blood sugar control in overweight adults who have higher-than-normal blood sugar. If you're between 18-40, overweight, and don't have diabetes, you may be able to join.
Leeds, Greater ManchesterAges 18–40 - NCT07081152Recruiting
Iron absorption and losses in young South African women
This study looks at how well young South African women absorb iron and how much iron they lose, comparing women with healthy weight to women with overweight or obesity. It aims to learn if body weight affects iron balance.
Potchefstroom, North WestAges 18–35 - NCT07090005Recruiting
Endoscopic weight loss: comparing EndoZip and Apollo ESG
This study compares two different endoscopic procedures (EndoZip and Apollo ESG) to help obese patients lose weight. Both are done through the mouth without cutting the skin, and the goal is to see which works better and is safer.
Los Angeles, CaliforniaAges 21–65 - NCT07098663RecruitingPhase 2
Study of MKP10241 for weight loss and diabetes control
This study tests an investigational drug called MKP10241 in healthy people, people with obesity, and people with type 2 diabetes. It aims to see how the drug affects blood sugar, weight, and overall safety. It may be an option if you have obesity or type 2 diabetes managed by diet and/or metformin.
Bayswater, VictoriaAges 18–60
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Common questions
- Are there clinical trials for overweight or obese adults?
- Yes. Clin2 currently lists 808 recruiting overweight or obese adults studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a overweight or obese adults trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a overweight or obese adults trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.