Clinical trials
Overweight or Obese Adults clinical trials
Below are recruiting overweight or obese adults clinical trials, each written for real people, not researchers. We’re tracking 800 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT06372015Recruiting
Diet program vs bariatric surgery for liver health
This study compares two ways to help people with obesity and liver problems: a special diet program or weight-loss surgery. Researchers will look at changes in fats, immune system, and genetic markers to see which approach works better.
Castellana Grotte, BariAges 18 years+ - NCT07223242RecruitingPhase 2/Phase 3
Tailored exercise training for heart failure with preserved pumping strength
This trial tests a personalized exercise program to help people with a type of heart failure called HFpEF. You may qualify if your heart still pumps well but you have trouble being active, and you are willing to use a phone app and exercise regularly.
Dallas, TexasAges 18 years+ - NCT07225816RecruitingPhase 1
How fasting affects stomach food with GLP-1 drugs
This study looks at how long fasting and temporarily stopping certain diabetes or weight-loss medications (like semaglutide or liraglutide) affects how much food stays in your stomach. It may help understand how these medications work in people who are overweight.
Cypress, CaliforniaAges 18 years+ - NCT07215533Recruiting
Exercise trials for teens and young adults at risk for diabetes
This study compares two types of exercise—high-intensity interval training (HIIT) and time-restricted eating (TRE)—to help lower the risk of developing type 2 diabetes in teens and young adults who are overweight or have obesity.
Syracuse, New YorkAges 14–30 - NCT07220265Recruiting
PKU carriers: How high phenylalanine affects the brain
This study looks at how carrying one copy of the PKU gene might affect thinking and brain health in adults. It will help researchers understand if mild changes in a substance called phenylalanine can impact memory, focus, and brain scans.
Columbia, MissouriAges 18–60 - NCT06509464Recruiting
High-intensity interval training for women with central obesity
This study tests whether high-intensity interval training can improve the severity of metabolic syndrome in women who carry extra weight around their belly. It may help you understand how exercise affects your overall health.
GizaAges 25–45 - NCT06745102Recruiting
Hop compounds for immune health in people with extra weight
This trial tests if compounds from hops can help the immune system of people who are overweight and showing early signs of metabolic issues like prediabetes, fatty liver, or mild high blood pressure.
ViennaAges 18–75 - NCT07211217Recruiting
Time-restricted eating for bipolar depression
This study tests if eating only during a specific daily window can help with weight loss and mood in people with bipolar disorder who are currently depressed and overweight.
Boston, MassachusettsAges 18–65 - NCT07193927RecruitingPhase 2
Testing a probiotic mix for fatty liver disease (MASLD)
This trial tests whether a probiotic mixture can improve liver health in people with moderate fatty liver disease (MASLD). It looks at how the probiotic affects liver fat, inflammation, and metabolism.
Girona, GironaAges 18–75 - NCT05300971Recruiting
Heat therapy to lower blood pressure in midlife and older adults
This study tests whether regularly using passive heat can lower your systolic blood pressure (the top number) and improve how your blood vessels work. If you’re eligible, you may be randomly assigned to try the heat therapy as a 6-month program.
Boulder, ColoradoAges 40 years+ - NCT06306196RecruitingPhase 2
Hepatitis E vaccine study in healthy adults, children, and people with HIV
This study tests a hepatitis E vaccine called Hecolin in healthy people (ages 2–45) and in adults (18–45) living with HIV who are on antiviral treatment. It aims to see how well the vaccine works and if it's safe for different groups.
Ga-RankuwaAges 2–45 - NCT07155993Enrolling by invitation
Long-term fasting and food reintroduction study
This study looks at what happens in your body during a long fast (5+ days) and when you start eating again. It may help you understand how fasting affects your health.
Überlingen, Baden-WurttembergAges 18–90 - NCT07160530Recruiting
Healthy eating help for rural child care homes
This study tests a program to help family child care providers in rural Nebraska and Kansas serve healthier meals and snacks to preschool children. It aims to improve children's eating habits.
Lincoln, NebraskaAges 3 years+ - NCT07154238Enrolling by invitation
Semaglutide for weight management: a real-world study
This study looks at the experiences of people using injectable semaglutide for weight loss, as well as the doctors who prescribe it. It aims to understand how the treatment works in everyday life.
Bad OeynhausenAges 18 years+ - NCT07131605Recruiting
How weight-loss surgery affects heart health and inflammation
This study looks at how weight-loss surgery affects heart health by checking markers of inflammation in the blood and how blood vessels work. It may help understand why surgery lowers heart risk for people with obesity.
Cotignola, RavennaAges 18 years+ - NCT06207110Recruiting
Family support program for children with high food responsiveness
This study tests a program for families with children ages 7–12 who have overweight or obesity and often feel strong urges to eat. The program helps parents support their child in eating healthier and being more active.
La Jolla, CaliforniaAges 7–12 - NCT07120802Recruiting
Better4All healthy habits pilot program
This study tests a personalized program using a wearable and an Android app to help people build healthier habits over three weeks. It's for adults who are at a normal weight or overweight and are comfortable using technology.
NicosiaAges 18–65 - NCT07107334RecruitingPhase 2
GLP-1 drug plus hormone IUD for early endometrial cancer in obesity
This trial tests if adding a GLP-1 weight-loss drug to a hormone-releasing IUD can help treat very early endometrial cancer or a precancerous condition in women with obesity. The goal is to see if this combination is effective without surgery.
Gainesville, FloridaAges 18 years+ - NCT07094568Recruiting
Comparing tirzepatide and liraglutide for bone health in severe obesity
This study compares two medicines, tirzepatide and liraglutide, to see how they affect bone health in people with severe obesity. If you have a high BMI and no major health problems, this trial could help doctors understand which treatment is better for your bones.
Athens, AtticaAges 30–65 - NCT07082062Recruiting
GLP-1 formula for glucose control
This trial tests whether a special GLP-1 formula can help regulate blood sugar and increase GLP-1 levels in people with higher body fat. It may offer a new way to support metabolic health.
TaichungAges 18–50 - NCT05235945Recruiting
Exercise program for people waiting for weight-loss surgery
This trial studies whether an exercise program can help people prepare for bariatric (weight-loss) surgery. It aims to see if exercise is safe and beneficial while you’re waiting for your surgery date.
LondonAges 18 years+ - NCT07073846RecruitingPhase 4
Lidocaine and dexmedetomidine for pain after weight-loss surgery
This study tests whether adding two medicines (lidocaine and dexmedetomidine) to your anesthesia during weight-loss surgery can reduce pain, swelling, and stress on the body. It might help you have a smoother recovery.
Mexico City, Mexico CityAges 18–60 - NCT07060079Recruiting
Using entropy to measure sleep breathing in chronic lung disease
This study uses a special mathematical method called entropy to better understand sleep-disordered breathing in people with chronic respiratory disease. If you have a long-term lung condition, this research could help improve how sleep breathing problems are detected and managed.
LondonAges 18 years+ - NCT07051109Recruiting
Dual-chamber pain pump for recovery after weight-loss surgery
This trial tests a dual-chamber patient-controlled pain pump after weight-loss surgery. It may help women have better pain relief and recovery.
Seongnam-si, Gyunggi-doAges 19–65
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Common questions
- Are there clinical trials for overweight or obese adults?
- Yes. Clin2 currently lists 800 recruiting overweight or obese adults studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a overweight or obese adults trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a overweight or obese adults trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.