Clinical trials
Overweight or Obesity clinical trials
Below are recruiting overweight or obesity clinical trials, each written for real people, not researchers. We’re tracking 1,536 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT05806801Recruiting
Study how weight loss changes the body with or without exercise
This study looks at how your metabolism (how your body uses energy and controls blood sugar/fats) changes during weight loss, comparing weight loss alone versus weight loss plus exercise. It may help researchers understand what body changes happen with different approaches and why.
Ann Arbor, MichiganAges 18–40 - NCT05816798RecruitingPhase 2/Phase 3
Laser treatment to reduce chronic knee pain before weight-surgery
This trial tests whether photobiomodulation (a type of laser/light therapy) can reduce chronic pain in both knees for people preparing for bariatric (weight-loss) surgery. If you have knee pain that limits daily life, the treatment may help you feel better while you’re in the pre-surgery rehabilitation period.
Goiânia, GoiásAges 18–70 - NCT05818384Recruiting
Health program for Choctaw youth to improve daily habits
This is a community health program for Choctaw Nation of Oklahoma youth that tries to improve habits related to food, movement, and screen time. It may help you build healthier routines for everyday life.
Durant, OklahomaAges 12–19 - NCT05819853RecruitingPhase 3
Semaglutide to help restart periods in PCOS
This Phase 3 study tests whether semaglutide can help people with polycystic ovary syndrome (PCOS) start ovulating and having more regular periods. You may join with or without metformin, and contraception rules are important because the medicine must not be used during pregnancy.
Aurora, ColoradoAges 12–35 - NCT05833217Recruiting
Study for persistent COVID symptoms with insulin resistance
This trial studies people who have ongoing effects after COVID (often called PASC) and may be related to weight and insulin resistance. It may help researchers find better ways to understand the condition and improve treatment.
Palo Alto, CaliforniaAges 18–80 - NCT05838950Recruiting
Short high-intensity exercise program for cardiometabolic health
This trial studies whether a structured, short high-intensity exercise program can improve health markers related to weight, blood sugar, and blood fats in young adults with obesity. It may help you see if this kind of exercise leads to measurable health improvements.
Syracuse, New YorkAges 18–25 - NCT05847478Recruiting
Acupressure vs eating plan breaks for specific stomach syndrome
This study compares ear (auricular) acupressure to an intermittent dietary restriction approach in children who have a particular “stomach heat and dampness” pattern from Traditional Chinese Medicine. The goal is to see which method better helps children with certain weight and blood-sugar or cholesterol risks.
ShanghaiAges 6–18 - NCT05859022Recruiting
Bariatric treatment methods compared for diabetes and metabolism
This trial compares a less invasive heart/artery-based bariatric treatment (bariatric arterial embolization) with standard weight-loss surgery to see how they affect metabolism and type 2 diabetes. You might be considered if you have obesity with type 2 diabetes and have not had prior bariatric surgery.
LisbonAges 18–75 - NCT05861973Recruiting
Smartphone program to support weight loss
This study tests a smartphone app (“SMARTer”) to help adults manage weight. You may be able to join if you have overweight and are not already in a structured weight loss program.
Tallahassee, FloridaAges 18 years+ - NCT05866406Recruiting
Time-restricted eating to improve heart and sugar health
This study tests whether eating only within a set daily time window can improve cardiometabolic health (things like blood sugar and heart-related measures). You may be eligible if you have overweight and borderline/high-risk blood sugar but do not have diabetes and can follow the eating and testing rules.
CambridgeAges 25–75 - NCT05880108Recruiting
Behavior program to help COVID recovery in Veterans
This study tests whether a behavioral (lifestyle) program can improve recovery from COVID-19, especially for Veterans with different body weights. It looks at people who either have never had COVID before or had COVID more than 90 days ago.
Baltimore, MarylandAges Up to 80 years - NCT05881447Recruiting
Study kidney disease patterns in people in Tanzania
This study looks at how common chronic kidney disease is, how it develops over time, and what risk factors are linked to it. It may help improve how kidney disease is recognized and managed in your community.
Bagamoyo, Coast RegionAges 18–99 - NCT05880758Recruiting
Studies how yo-yo sleep affects heart and metabolism health
This study looks at what happens to heart-related health and body metabolism when your sleep goes through ups and downs (yo-yo sleep). You may be asked about your sleep habits and health history to see whether your body changes in response to different sleep patterns.
New York, New YorkAges 18–49 - NCT05880901RecruitingPhase 2
After-school programs for kids from low-income families
This study tests whether participating in after-school and summer programs improves outcomes for children in kindergarten through 4th grade. It mainly focuses on kids attending partner schools and whose families qualify for free or reduced-price lunch.
Columbia, South CarolinaAges 5–12 - NCT05881759Recruiting
Food and feeding support program for parents
This study tests whether combining “Food Rx” (food support) with best feeding practices helps parents improve how they feed their 4–8 year old children. If you join, you’ll complete surveys and participate in a parent support program using phone and internet.
Houston, TexasAges 18–64 - NCT05901675Recruiting
Weight loss and exercise after stroke in walking recovery
This trial studies whether a weight-loss plan combined with exercise can improve walking and leg movement after stroke. It may help if you have ongoing leg weakness but can still walk without devices for testing.
Charleston, South CarolinaAges 35–85 - NCT05912348Recruiting
Study of how an unhealthy lifestyle affects active young adults
This study looks at how eating or daily habits that promote weight gain (“obesogenic” lifestyle) affect fitness and health markers in young adults who already exercise. It may help researchers understand what lifestyle changes matter most, and whether certain patterns affect active people differently.
Durham, New HampshireAges 18–30 - NCT05919797RecruitingPhase 4
Weight loss genetics study with naltrexone and bupropion
This trial studies how your genetic makeup and body response may affect weight loss with a medication combination called naltrexone and bupropion. If you qualify, you’ll likely take these medicines and be monitored for safety and changes in weight over time.
New York, New YorkAges 18–65 - NCT05935111Recruiting
Physical activity program for adults who can track activity
This study tests whether an online physical activity program is practical and doable for adults who meet certain health and tech access requirements. It may help you build a routine and see if you can stick with activity tracking using a wearable device and daily check-ins.
Binghamton, New YorkAges 18–64 - NCT05935826RecruitingPhase 3
Amino acids to reduce liver fat in teens with NAFLD
This study tests whether adding amino acids can lower fat stored in the liver of teens with non-alcoholic fatty liver disease (NAFLD). It may help improve liver health by changing how much liver fat is present over the study period.
Aurora, ColoradoAges 13–18 - NCT05950282Recruiting
Study of insulin sensitivity differences by age and PCOS status
This study looks at how well the body uses insulin (insulin sensitivity) across different ages, sexes, races, body weights, and whether someone has PCOS. It may help researchers understand why insulin function varies and how PCOS could be linked to metabolic health.
Houston, TexasAges 18 years+ - NCT05963971Recruiting
Bilingual online program to prevent weight gain in childhood leukemia
This trial tests a bilingual, online program to help children and teens who have ALL (a type of leukemia) stay at a healthy weight during the maintenance phase of treatment. It may help lower the chance of gaining too much weight while on chemotherapy.
New York, New YorkAges 5–21 - NCT05972564RecruitingPhase 1/Phase 2
SGLT2 drug trial for belly fat inflammation before weight-loss surgery
This early-phase trial tests whether an SGLT2 drug can reduce inflammation in belly fat and improve blood vessel function. It may help people with metabolic syndrome prepare for (and potentially benefit around) planned gastric bypass or sleeve surgery.
Nashville, TennesseeAges 18 years+ - NCT05975580RecruitingPhase 4
Medication plus lifestyle counseling for weight regain after bariatric surgery
This study looks at whether adding medication to lifestyle counseling can help people who have regained weight after sleeve gastrectomy or gastric bypass. It focuses on improving weight control and related health after surgery.
Orange, CaliforniaAges 18–70
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Common questions
- Are there clinical trials for overweight or obesity?
- Yes. Clin2 currently lists 1,536 recruiting overweight or obesity studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a overweight or obesity trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a overweight or obesity trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.