Clinical trials
Overweight or Obesity clinical trials
Below are recruiting overweight or obesity clinical trials, each written for real people, not researchers. We’re tracking 1,472 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT06924320RecruitingPhase 1/Phase 2
Study of two medicines for weight loss and diabetes
This study tests two investigational medications, MET233 and MET097, in people with obesity or overweight, with or without type 2 diabetes. It aims to see if the combination can help with weight loss and blood sugar control.
Cypress, CaliforniaAges 18–75 - NCT06755827RecruitingPhase 1/Phase 2
Online weight program for teens 11–14
This study tests a new online program to help teenagers ages 11–14 with overweight or obesity. It uses group meetings and brain scans (MRI) to understand how the program works and if it helps.
Lubbock, TexasAges 11–14 - NCT06722443Enrolling by invitation
Probiotics and Prebiotics for Obesity
This trial tests whether adding probiotics and prebiotics to your diet can help with obesity and related health problems like prediabetes, diabetes, high cholesterol, or high blood pressure.
Granada, SpainAges 18–75 - NCT06512818Enrolling by invitationPhase 1/Phase 2
Testing Psiguavin for weight loss in obesity
This study tests a natural supplement made from guava (called Psiguavin) to see if it helps with weight loss in people who are overweight or have obesity. Participants will take the supplement and be monitored for weight changes and safety.
MurciaAges 18–65 - NCT05798494Recruiting
Pre-pregnancy weight loss plan to protect child weight
This study tests whether a very low-calorie weight loss program before pregnancy can improve the chance that a child will have a healthier weight later. It follows families and stores samples from the child at home.
AarhusAges 18–38 - NCT06268262Recruiting
Obesity brain imaging study before and after surgery
This study uses brain scans to understand how obesity affects the brain and how bariatric surgery may change it. It compares people with obesity who are planning surgery to healthy volunteers.
Xuzhou, JiangsuAges 18–65 - NCT07846033RecruitingPhase 1
Study of the experimental drug VK3019 for adults with overweight or obesity
This early-phase study tests an experimental medicine called VK3019 in adults who are overweight or have obesity but are otherwise healthy. The goal is to see if the drug is safe and how the body handles it, which may lead to future weight-management options.
Lake Forest, CaliforniaAges 18–60 - NCT05713448Recruiting
Check how common overweight is in adults with type 1 diabetes
This study looks at how many adults with type 1 diabetes have overweight or obesity. It may help improve future care planning for people living with type 1 diabetes.
LeuvenAges Any age - NCT04614961Recruiting
Obesity clinic patient database study
This study collects information about people who visit an obesity clinic. It aims to better understand patients’ health and care needs, which may improve future treatment.
LeuvenAges 18 years+ - NCT07817069Recruiting
Nitraria retusa tea for weight issues caused by clozapine
This trial tests whether a tea made from the plant Nitraria retusa can help reduce the weight gain and metabolic side effects caused by the medication clozapine. If you take clozapine for schizophrenia and have gained weight, this tea might help you manage that side effect.
SousseAges 18–65 - NCT07776678Recruiting
Body fat and muscle measurement study
This study uses advanced body scans (like MRI and DXA) to better measure body fat and muscle. It may help improve how obesity is diagnosed and treated.
Phoenix, ArizonaAges 18 years+ - NCT07780188Recruiting
Lean beef in a healthy meal plan for teens with PCOS
This study tests whether adding lean beef to a healthy meal plan can help teens with PCOS improve their health. You'll follow a special diet and wear a small monitor to track your blood sugar, and the study may help you feel better and manage your condition.
College Station, TexasAges 11–17 - NCT07768813RecruitingPhase 1
Comparing two versions of an injected drug in healthy and overweight people
This trial compares two different versions of an injected study drug (survodutide) to see how they are absorbed by the body. It is open to healthy people and people with overweight or obesity, and it may help researchers find a better way to deliver this treatment.
MannheimAges 18–55 - NCT07774676Recruiting
Effects of obesity on muscle cell processes
This study looks at how obesity affects certain cell processes in muscle. It may help find new ways to treat or prevent muscle problems related to obesity.
BirminghamAges 18–45 - NCT06067906Recruiting
Weight loss diet after pre-eclampsia in overweight women
This trial tests whether a special diet (either a low-calorie or a 'dissociated' diet) helps women who have had pre-eclampsia lose weight. It may help you reduce future health risks.
Le MansAges 18–45 - NCT07732426Recruiting
Semaglutide and brain response to food in obesity with food addiction
This trial tests if semaglutide can change how your brain responds to food cues, like seeing or smelling food, in people with obesity and a tendency toward food addiction. It may help understand why some people struggle with overeating and how this medication could help.
SeoulAges 19–50 - NCT07728383RecruitingPhase 4
Obesity treatment study using tongue-applied semaglutide
This trial tests a new way to deliver semaglutide through a strip placed on the tongue for weight loss in adults with obesity. It may help you lose weight without a needle.
Minneapolis, MinnesotaAges 18–65 - NCT07715955Recruiting
Can probiotics help control appetite in adults with overweight or obesity?
This study tests whether taking probiotics can help regulate appetite in people who are overweight or have obesity. It aims to understand if these supplements can support weight management by affecting hunger and fullness signals.
Maastricht, LimburgAges 20–70 - NCT07699445RecruitingPhase 4
Lumateperone for weight and mood in bipolar depression
This study tests if lumateperone, a medication for bipolar depression, can also help with weight and aging in people with obesity. You may qualify if you have bipolar I depression and a body mass index (BMI) over 30.
Boston, MassachusettsAges 18–65 - NCT07703683Recruiting
Muscle health in metabolic and hormone diseases
This trial looks at how muscle health is affected by metabolic or hormone disorders, aiming to find better markers for muscle loss called sarcopenia.
Woluwe-Saint-Pierre - Sint-Pieters-WoluweAges 18 years+ - NCT07690163Recruiting
Diabetes blood sugar check in newly diagnosed patients
This trial is checking how well blood sugar is controlled in adults recently diagnosed with type 2 diabetes (within the last 3 months). It aims to see if current treatments or lifestyle changes are working and may help guide future care.
KyivAges 18 years+ - NCT07681856Enrolling by invitation
Immersive exercise program for overweight teens
This trial tests a virtual reality exercise program designed to help overweight teenagers become more active. It may improve physical fitness and health in a fun, engaging way.
Vigo, PontevedraAges 12–16 - NCT06626360Recruiting
Screening for malnutrition in people with obesity
This study looks at whether overweight or obese patients may also be malnourished. Researchers will screen people with a BMI of 25 or higher to find hidden malnutrition so they can get the right nutritional support.
AmsterdamAges 18 years+ - NCT07654179Recruiting
Metformin for depression with obesity: a genetic study
This trial tests if adding metformin to antidepressants helps people who have both depression and obesity. It also looks at genetic factors that might affect treatment response.
Rawalpindi, Punjab ProvinceAges Any age
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Common questions
- Are there clinical trials for overweight or obesity?
- Yes. Clin2 currently lists 1,472 recruiting overweight or obesity studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a overweight or obesity trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a overweight or obesity trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.