Clinical trials · Missouri
Overweight clinical trials in Missouri
We’re tracking 29 recruiting overweight studies with a site in Missouri — including Phase 2 and Phase 3 studies, each written for real people, not researchers.
Recruiting studies in Missouri
- NCT07575932RecruitingPhase 2
Testing New Weight Loss Medications PF-08653945 and PF-08653944
This study tests two new experimental medications designed to help adults lose weight and improve weight-related health conditions like high blood pressure and sleep apnea. Participants will take one of these medications to see if it's safe and effective.
Springfield, MissouriAges 18 years+ - NCT06937086RecruitingPhase 3
Mirikizumab plus tirzepatide for UC with obesity
This study tests whether adding mirikizumab to the weight-loss drug tirzepatide helps people with moderate-to-severe ulcerative colitis who also have obesity or overweight. It aims to see if the combination reduces bowel inflammation and helps with weight management.
St Louis, MissouriAges 18–70 - NCT06937099RecruitingPhase 3
Testing two drugs for Crohn's with weight issues
This trial tests two study drugs, mirikizumab and tirzepatide, in people with moderate to severe Crohn's disease who also have overweight or obesity. The goal is to see if these treatments can help control Crohn's symptoms and inflammation.
St Louis, MissouriAges 18–70 - NCT07662122RecruitingPhase 2
Testing a new weight loss medication in adults with obesity or overweight
This trial tests an investigational drug called BI 3034701 to see if it helps people lose weight. It is for adults who are obese or overweight with at least one weight-related health problem.
City of Saint Peters, MissouriAges 18–74 - NCT07743463RecruitingPhase 3
Daily pill for weight loss in adults with overweight or obesity
This trial tests an investigational once-daily pill (ASC30) to see if it can help adults with overweight or obesity lose weight. You may be able to join if you have a high body mass index (BMI) and have tried to lose weight before.
St Louis, MissouriAges 18 years+ - NCT07743450RecruitingPhase 3
Once-daily pill for weight loss in people with type 2 diabetes
This study tests an oral medication, ASC30, to see if it helps people with type 2 diabetes who are overweight or obese lose weight and improve blood sugar control. It is a once-daily pill that may offer a new treatment option.
Columbia, MissouriAges 18 years+ - NCT07351045RecruitingPhase 3
Study of enicepatide for weight loss in obesity or overweight
This study tests a new injectable medication called enicepatide for people with obesity or overweight who have not been able to lose weight through diet and exercise alone. It may help you lose weight and improve health conditions linked to excess weight.
Springfield, MissouriAges 18 years+ - NCT07654374RecruitingPhase 3
Study of a new pill for weight loss and diabetes
This study tests a new daily pill (aleniglipron) to help adults with excess weight and type 2 diabetes lose weight and improve blood sugar control. It may be a good fit if you have a BMI of 27 or higher and your diabetes is managed with A1c between 6.5% and 10%.
Chesterfield, MissouriAges 18–79 - NCT07654361RecruitingPhase 3
A new pill for weight loss in obesity and overweight
This study tests an investigational pill called aleniglipron to see if it helps people with obesity or overweight who also have a weight-related health problem (like high blood pressure) lose weight safely. It is a Phase 3 trial, meaning it is in the final stages before seeking approval.
Chesterfield, MissouriAges 18–79 - NCT07369011RecruitingPhase 3
Study of eloralintide for sleep apnea with obesity
This study tests an investigational medication called eloralintide to see if it can improve sleep apnea in people who are overweight or have obesity. You will receive either the study drug or a placebo (inactive shot), and your sleep and weight will be monitored over time.
St Louis, MissouriAges 18 years+ - NCT07497880RecruitingPhase 2
Study of a new pill for weight loss in adults with obesity
This trial tests a daily pill called KAI-7535 to see if it helps people with obesity or overweight lose weight safely. It is for adults who have a body mass index (BMI) of 27 or higher and at least one weight-related health problem, such as high blood pressure or type 2 diabetes.
Jefferson City, MissouriAges 18–75 - NCT07037433RecruitingPhase 3
Heart protection study for people with heart disease and overweight
This study tests a new weekly injection (maridebart cafraglutide) to see if it helps lower the risk of heart problems in people with heart disease and overweight. It is for adults who have had a heart attack, stroke, or artery blockages and also have a BMI of 27 or higher.
City of Saint Peters, MissouriAges 45–99 - NCT06672549RecruitingPhase 3
Weight loss medication study for children with obesity
This trial tests a medication for children and teens with obesity or overweight who have not been able to lose enough weight with diet and exercise alone. It aims to see if a new treatment can help them safely lose weight and improve related health problems.
St Louis, MissouriAges 6–17 - NCT06672939RecruitingPhase 3
Orforglipron for Weight Loss in Teens
This study tests a once-daily pill (orforglipron) to help adolescents with obesity or overweight plus related health problems lose weight. It offers a new option for teens who have struggled to lose weight with diet and exercise alone.
St Louis, MissouriAges 12–17 - NCT05277558Recruiting
MRI and brain testing in teens at risk for type 2 diabetes
This study looks at brain health in teens with normal weight, overweight, or obesity who are at risk for type 2 diabetes. It may help researchers understand how weight and diabetes risk affect the brain, using MRI scans and learning/memory tests.
St Louis, MissouriAges 12–17 - NCT06143956RecruitingPhase 2
Weight loss treatments for adults with obesity
This clinical trial tests new treatments for adults who are overweight or have obesity. The goal is to help people lose weight and improve their health.
City of Saint Peters, MissouriAges 18–75 - NCT07282600RecruitingPhase 3
Study of eloralintide for type 2 diabetes and weight
This study tests a new medicine called eloralintide for people with type 2 diabetes who are overweight or have obesity. It aims to see if the drug can help with weight loss and blood sugar control.
Chesterfield, MissouriAges 18 years+ - NCT07441252RecruitingPhase 2
Study of maridebart cafraglutide for fatty liver with obesity
This trial tests a new medication (maridebart cafraglutide) to see if it can reduce fat in the liver and help with weight loss. It may be an option for adults with excess liver fat and obesity or overweight who haven't been able to lose weight with diet and exercise alone.
Kansas City, MissouriAges 18–99 - NCT07589608RecruitingPhase 2
Weight Loss Study With Two New Injectable Medications
This study tests two new injectable drugs (macupatide and eloralintide) alone or together to help adults with obesity or excess weight lose weight. The goal is to see if these medications are safe and effective for weight management.
City of Saint Peters, MissouriAges 18–75 - NCT07392190RecruitingPhase 3
Study of eloralintide for people with persistent obesity
This trial tests if adding eloralintide helps people who are still obese or overweight while taking weekly incretin therapy. It aims to support additional weight loss for those who haven't reached their goals.
Chesterfield, MissouriAges 18 years+ - NCT07770841RecruitingPhase 3
Oral medication for weight loss study
This study tests an oral medicine (semaglutide) to see if it helps adults with excess weight lose weight. It might offer an easier, pill-based treatment option for weight management.
City of Saint Peters, MissouriAges 18 years+ - NCT07153471RecruitingPhase 3
A study of an experimental pill for weight loss and knee arthritis
This trial tests an investigational medication (orforglipron) to see if it helps people with knee arthritis lose weight. You may qualify if you have overweight or obesity and have tried dieting before without lasting success.
City of Saint Peters, MissouriAges 18 years+ - NCT07667803RecruitingPhase 3
Study of elecoglipron for weight loss in obesity or overweight
This trial tests an investigational drug called elecoglipron to see if it helps people with obesity or overweight lose weight. It may be an option if you have a high body mass index or weight-related health issues like high blood pressure or prediabetes.
Kansas City, MissouriAges 18 years+ - NCT06969235Recruiting
Family weight loss program for teens
This study tests a family-based weight loss program for teens ages 13-17 who have overweight or obesity. It looks at how thinking skills (like planning and focus) affect the program's success.
Columbia, MissouriAges 13–17
Overweight trials by city in Missouri
Where these studies are running in Missouri
Institutions with a site for the recruiting overweight studies listed above.
- StudyMetrix Research · 6 studies
- Alliance for Multispecialty Research (AMR) - Kansas City · 3 studies
- Clinvest Headlands LLC · 3 studies
- Research Site · 3 studies
- Washington University in St. Louis · 3 studies
- ACCOMPLISH-1 Research Site · 2 studies
- Aurora Clinical Site · 2 studies
- Clinical Research Professionals · 2 studies
What taking part in a overweight study involves
A screening visit first
Before anything else, the study team checks whether you fit — usually a visit with some tests. You can stop at any point, and screening is typically free.
Care at a nearby site
Study visits happen at a clinic or hospital taking part. Many studies cover the cost of the study treatment and related visits, and some reimburse travel.
You stay in control
Taking part is voluntary and you can leave a study at any time, for any reason, without affecting your regular care.
The team decides eligibility
Our fit check is a helpful first read, not a decision. The study team makes the final call after reviewing your health history.
Overweight trials in other states
Common questions
- Are there overweight clinical trials in Missouri?
- Yes. We're currently tracking 29 recruiting overweight studies with a site in Missouri, each rewritten in plain language so you can see what it's testing and who it's for.
- How do I find out if I qualify for a overweight study in Missouri?
- Each study lists its eligibility rules — age, diagnosis, prior treatments. On every trial page we explain these in plain language and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Do I have to live in Missouri to take part?
- Not necessarily. These studies have a site in Missouri, but eligibility is about your health, not your address — some people travel to take part, and a few studies reimburse travel. The study team can tell you what's required.
- Does it cost anything to join a overweight trial?
- Using Clin2 is always free. Many trials cover the study treatment and related visits; some reimburse travel. The study team explains exactly what's covered before you decide.
Not the right time?
New overweight studies open in Missouri regularly. Set up a health profile and we’ll quietly watch for studies that fit you and email you when one opens.
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.