Clinical trials
Oxygenation clinical trials
Below are recruiting oxygenation clinical trials, each written for real people, not researchers. We’re tracking 383 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT04647656Recruiting
Hyperbaric oxygen for lingering post-COVID brain fog
This study tests whether breathing pure oxygen in a pressurized chamber (hyperbaric oxygen therapy) can improve long-lasting post-COVID problems with thinking and memory. It may help if your brain symptoms have lasted at least 3 months and affect your daily life.
ẔerifinAges 18 years+ - NCT04307615Recruiting
Oxygen versus CPAP during emergency lung fluid episodes
This trial tests whether regular oxygen or CPAP (a breathing-support machine) works better for people who have swimming-induced pulmonary edema, a sudden buildup of fluid in the lungs after swimming. It may help doctors choose the safest and most effective breathing treatment in an emergency.
FalunAges 18 years+ - NCT03964506RecruitingEarly Phase 1
Hyperbaric oxygen plus donor stem cell transplant for blood cancers
This early-phase trial studies whether breathing pure oxygen in a pressurized chamber, along with a donor stem cell transplant, can improve outcomes for certain blood cancers. It may help by supporting the body during transplant and recovery, but it is still being tested for safety and effectiveness.
Rochester, New YorkAges 18–75 - NCT03758508Recruiting
Noninvasive breathing support versus high-flow oxygen for pneumonia
This study compares two ways to help breathing in adults with pneumonia who have low oxygen levels: a noninvasive breathing machine versus high-flow oxygen. It aims to see which option helps patients breathe better and avoid getting worse.
MilanAges 18 years+ - NCT03511846Enrolling by invitationPhase 1
Pain biomarker study for headache or back nerve pain
This study looks at measurable “pain signals” (biomarkers) in people with certain headache disorders or lumbar nerve pain, and compares them with healthy people. It may help researchers better understand what drives pain and how it can be detected.
Houston, TexasAges 18 years+ - NCT07585890Recruiting
Liver Transplant Outcomes With Machine Preservation in Europe
This study collects information about how livers do after transplantation when they've been preserved using machine perfusion—a technique that keeps donor livers in better condition before surgery. Researchers want to understand which preservation methods work best to improve transplant success across Europe.
InnsbruckAges 18 years+ - NCT04330651Recruiting
Extra-support machine for heart patients after surgery
This study looks at using an external life-support machine after heart surgery. It may help patients who need temporary extra support while the heart and body recover.
FlorenceAges 18–80 - NCT05155904Recruiting
Study outcomes for adults on VA ECMO
This study looks at the results (outcomes) for adults who are receiving VA ECMO, a heart-lung life support machine. The goal is to better understand how patients do while on this type of support.
AmiensAges 18 years+ - NCT04791488Recruiting
Testing oxygen level effects after diving or oxygen therapy
This study looks at how breathing extra oxygen (hyperoxia) and the body’s immune response change after diving or when people need hyperbaric oxygen therapy. It may help doctors understand what to expect and how to manage recovery after a diving accident.
ToulonAges 18 years+ - NCT05698628Recruiting
Timing strategies to protect legs during peripheral ECMO
This trial studies whether an “early” or more “conservative” approach to improving blood flow to the leg can prevent limb damage during a type of heart-lung machine called peripheral VA-ECMO. It may help reduce the risk of poor leg blood flow (ischemia) in people with severe heart failure-related shock.
SeoulAges 19 years+ - NCT05825092RecruitingPhase 2
Early testosterone gel for people on breathing machines
This Phase 2 study tests whether starting testosterone gel soon after ICU admission can improve physical performance in critically ill adults who need a breathing machine for more than 48 hours. It’s also designed to check safety in this setting.
BordeauxAges 18–79 - NCT07854431Recruiting
Measuring brain blood flow with light in healthy adults
This study uses a safe, non-invasive light-based technique called near-infrared spectroscopy (NIRS) to measure blood flow and oxygen in the brain. It aims to test a new monitoring device in healthy volunteers aged 20 to 40 to make sure it works correctly.
DüsseldorfAges 20–40 - NCT07865780Enrolling by invitationPhase 1/Phase 2
Laser light with or without oxygen gel for mouth sores from radiation
This study tests two ways to treat painful mouth sores caused by radiation therapy for head and neck cancer. Half of the participants will receive laser light therapy alone, and the other half will receive laser light plus an oxygen gel applied to the sores. The goal is to see if adding the oxygen gel helps the sores heal faster and reduces pain.
AsyutAges 18 years+ - NCT07867431Recruiting
Breathing exercises after heart stent procedure
This study tests two simple breathing exercises to see which one better helps oxygen levels and heart rate stability after a heart stent placement. It aims to improve recovery and overall heart function.
RawalpindiAges 44–75 - NCT06013319RecruitingPhase 3
Esmolol for better oxygen in ARDS patients
This trial tests if esmolol, a heart-slowing drug, can improve oxygen levels in patients with acute respiratory distress syndrome (ARDS) who are on a breathing machine. It may help by adjusting heart rate to a specific range.
Jinan, ShandongAges 18–65 - NCT06400797Recruiting
ECMO patient outcomes and quality of life study
This study follows people who are on ECMO (a machine that supports heart and lung function) to see how they do and what their quality of life is like afterward. It helps doctors learn more about long-term recovery.
Düsseldorf, North Rhine-WestphaliaAges 18 years+ - NCT06418165Recruiting
Cooled oxygenated machine perfusion for liver transplant
This study tests a new way to preserve donated livers using a machine that keeps the organ cool and oxygenated before transplant. It may help improve how well the liver works after the surgery.
ViennaAges 18 years+ - NCT05680246Recruiting
Study of long-term outcomes after special donor-liver preservation
This study looks at how well people do in the long run after liver transplant using donor livers that were preserved in a specific machine called DHOPE for more than 4 hours. It may help doctors understand whether this preservation method leads to better transplant outcomes over time.
GroningenAges 18 years+ - NCT07852728RecruitingPhase 2
Oxygen therapy for first responders after head injuries
This trial tests whether hyperbaric oxygen therapy (breathing pure oxygen in a pressurized chamber) can improve thinking, mood, and overall well-being in first responders who have had a traumatic brain injury and still have symptoms. If you are a first responder dealing with ongoing brain injury symptoms, this study could help you find new ways to feel better.
Boise, IdahoAges 18–75 - NCT04490317Recruiting
Study follows people with carbon monoxide poisoning in Korea
This study looks at people who have been sickened by carbon monoxide (CO) from an accident or exposure. It aims to better understand what happens over time, which could help improve care and outcomes in the future.
Wŏnju, Gangwon-doAges Any age - NCT07796971Recruiting
Exercise in low vs normal oxygen for weight and gut health
This study tests two exercise programs—one in low oxygen, one in normal oxygen—to see which is better at reducing body fat and improving gut health in adults aged 50–75 who are overweight or obese. You'll do high-intensity interval training (short bursts of intense exercise) and we'll monitor your results over time.
Bellerive-sur-AllierAges 50–75 - NCT07799454Recruiting
Skin sensor study for ICU patients needing blood oxygen checks
This study tests a new adhesive sensor that measures blood oxygen through the skin without needing as many blood draws. It may help ICU patients get faster, more comfortable oxygen monitoring.
Chapel Hill, North CarolinaAges 18–85 - NCT07785141Recruiting
Monitoring heart oxygen during pediatric open-heart surgery
This study uses a non-invasive light-based technique to monitor oxygen levels in the heart muscle during open-heart surgery in children. It aims to see if this method can help doctors better manage the surgery and improve outcomes.
Helsinki, UusimaaAges 1–17 - NCT05562505Recruiting
Using ECMO to help you breathe, sit up, and come off a ventilator
This trial tests whether a heart-lung machine called venovenous ECMO can help people with severe breathing failure get less sedated, get extubated (have the breathing tube removed), and start moving. It’s for certain adults who are on a ventilator for a short time and have specific oxygenation problems.
Darlinghurst, New South WalesAges 18–65
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Common questions
- Are there clinical trials for oxygenation?
- Yes. Clin2 currently lists 383 recruiting oxygenation studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a oxygenation trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a oxygenation trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.