Clinical trials
Oxygenation clinical trials
Below are recruiting oxygenation clinical trials, each written for real people, not researchers. We’re tracking 383 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT06244160Recruiting
High-flow oxygen therapy for spinal cord injury
This trial tests if high-flow oxygen therapy can help people with spinal cord injuries between the neck and upper back. It is designed for those admitted to a spinal injury ward within 24 to 48 hours of injury.
CardiffAges 18 years+ - NCT06711016Recruiting
Managing brain oxygen after emergency life support
This trial tests a targeted approach to manage oxygen levels in the brain for patients who received ECMO (a machine that does the heart and lung work) after a cardiac arrest that did not respond to standard CPR. The goal is to improve brain recovery and outcomes.
Jinan, ShandongAges 18–75 - NCT06683599Recruiting
Oxygen via nasal tube for babies during breathing tube placement
This study tests whether giving extra oxygen through a small tube in the nose during placement of a breathing tube helps young children stay safer. It is for newborns and infants up to about 1 year old who need a breathing tube for surgery or other non-emergency procedures.
Perth, Western AustraliaAges 1 minute–12 months - NCT06691165RecruitingPhase 1/Phase 2
Low oxygen therapy for blood pressure in spinal cord injury
This trial tests whether breathing low oxygen (hypoxia) can help stabilize blood pressure in people with spinal cord injuries. It's looking for participants with chronic cervical injuries to see if this therapy improves 24-hour blood pressure control.
Kelowna, British ColumbiaAges 19–65 - NCT06609694Recruiting
Comparing oxygen delivery methods for children with sleep apnea
This study tests a new way to give oxygen to children aged 5-17 who have obstructive sleep apnea (a condition where breathing stops briefly during sleep). It aims to see if a demand oxygen delivery system works better than standard care. This could help children with Down syndrome who often have untreated sleep apnea.
Cincinnati, OhioAges 5–17 - NCT06602557RecruitingPhase 2
Inhaled antibiotic for lung infection during ECMO support
This trial tests whether adding an inhaled antibiotic (amikacin) to standard IV antibiotics can better treat a serious lung infection (pneumonia caused by Gram-negative bacteria) in patients on a heart-lung machine (ECMO) and a breathing tube. If you or your loved one is on ECMO and has this type of pneumonia, this study may offer a new treatment approach.
ParisAges 18 years+ - NCT06406842Recruiting
Brain oxygen and stroke risk in carotid surgery
This study looks at whether monitoring oxygen levels in the brain during carotid artery surgery can help predict or prevent a stroke. If you are having this surgery, researchers want to see if a simple monitor on your forehead can warn the surgical team of trouble.
Beijing, Beijing MunicipalityAges 18–80 - NCT06493851Recruiting
Hyperbaric oxygen therapy to speed recovery after ACL reconstruction
This trial tests whether hyperbaric oxygen therapy (breathing oxygen in a pressurized chamber) can help you recover faster after ACL knee surgery. If you're having ACL reconstruction, this treatment might reduce healing time.
ZrifinAges 18–45 - NCT06452095Recruiting
Hyperbaric oxygen therapy for long COVID brain fog
This trial tests if hyperbaric oxygen therapy (breathing pure oxygen in a pressurized chamber) helps with long COVID symptoms, especially brain fog and thinking problems. It may be an option if you have had lingering symptoms for at least 2 months and can travel to one of the study sites.
Toronto, OntarioAges 18 years+ - NCT05237232Recruiting
MRI study of blood vessel changes after ECMO in infants
This study uses a brain MRI with a special blood-vessel scan to see how circulation changes after a life-support machine called ECMO in young children. It may help doctors better understand what happens in the brain after ECMO and improve care.
ParisAges Up to 17 years - NCT06275555Recruiting
Bivalirudin for blood thinning in ECMO patients
This trial tests if bivalirudin is a safe and effective blood thinner for people on ECMO, a machine that helps your heart and lungs. You may be eligible if you need this therapy and have no past reactions to similar medicines.
Beijing, Beijing MunicipalityAges 18 years+ - NCT06238050Recruiting
Oxygen therapy for severe leg artery disease
This trial tests whether breathing pure oxygen at normal pressure can help people with severe, long-lasting lack of blood flow in their legs. It may offer a way to improve oxygen delivery to the leg and possibly avoid amputation.
AngersAges 18 years+ - NCT06230731Recruiting
Oxygen levels in colon blood vessels during colonoscopy
This study measures oxygen levels in the colon during a routine colonoscopy to understand how blood flow differs between people with vascular lesions (abnormal blood vessels) and those with a healthy colon. It may help doctors better diagnose and treat these conditions.
Chicago, IllinoisAges 18–89 - NCT06213168Recruiting
CPAP plus high-flow oxygen vs oxygen alone for breathing failure
This study tests whether adding a breathing machine (CPAP) to high-flow oxygen can help people with sudden breathing failure more than high-flow oxygen alone. It is for adults recently admitted to the ICU with low oxygen levels.
AmiensAges 18 years+ - NCT06087315Recruiting
Study of oxygen use in children's hospitals
This study looks at how hospitals in six countries use pulse oximeters and oxygen therapy to treat children. It aims to find ways to improve oxygen delivery and care for children with serious illnesses.
Phnom PenhAges birth–15 years - NCT06053164RecruitingPhase 2
Portable oxygen for activity in mild-to-moderate lung disease
This study is testing whether using portable oxygen during physical activity can help people with mild-to-moderate interstitial lung disease feel better and be more active. It is for people whose oxygen levels drop during exercise but are normal at rest.
Edmonton, AlbertaAges 18–85 - NCT05987852Recruiting
Hyperbaric oxygen therapy for ulcerative colitis flare
This trial tests if hyperbaric oxygen therapy (breathing pure oxygen in a special chamber) can help people hospitalized with a moderate to severe ulcerative colitis flare get better faster. You will receive the therapy along with standard steroid treatment.
Birmingham, AlabamaAges 18–85 - NCT05959252RecruitingPhase 2
Bivalirudin vs heparin for blood thinning during ECMO
This Phase 2 trial compares two blood-thinning medicines—bivalirudin and heparin—in people on ECMO (a machine that supports breathing and/or circulation). It aims to see which medicine works better and is safer while you are connected to the ECMO circuit.
Sydney, New South WalesAges 18 years+ - NCT05842239Recruiting
Hyperbaric oxygen therapy for low sperm count infertility
This trial tests whether breathing 100% oxygen in a pressurized chamber (hyperbaric oxygen therapy) can improve fertility in men who have an unexplained low sperm count. It may help by improving sperm health, but you would need multiple sperm tests and to be able to follow the clinic schedule.
ẔerifinAges 21 years+ - NCT05699005RecruitingPhase 1
Personalized or standard blood transfusion during heart-lung machine
This trial tests whether giving blood in a personalized way, instead of a standard approach, is better for people on a heart-lung bypass machine (VA-ECMO) for heart-related shock. It may help find a safer blood transfusion strategy while you are critically ill.
Lille, NORDAges 18 years+ - NCT05691218Recruiting
Early high-flow oxygen plus nebulized asthma medicine
This study tests whether giving fast, high-flow oxygen early—together with inhaled terbutaline via a vibrating mist—helps adults with moderate to severe asthma flare-ups in the emergency department. It aims to see if this approach improves breathing after initial treatment.
Poitiers, FranceAges 18 years+ - NCT05686850Recruiting
Noninvasive breathing support vs high-flow oxygen after ICU extubation
This study compares two breathing supports used after a breathing tube is removed in the ICU: a noninvasive ventilator (mask-based) versus high-flow nasal oxygen. It aims to see which one works better when patients develop breathing trouble soon after extubation.
BrusselsAges 18 years+ - NCT05681624Recruiting
Extra oxygen during labor to support the baby
This trial studies whether giving extra oxygen to the pregnant person during labor helps the baby during “intrauterine resuscitation,” when monitoring suggests the baby needs support. It may help babies recover better while still in the womb, especially during continuous fetal monitoring.
St Louis, MissouriAges Any age - NCT05447416Recruiting
Intermittent low-oxygen training versus oxygen chamber training
This study compares two ways of training the body for better aerobic fitness: short, controlled low-oxygen workouts versus treatment in a hyperbaric oxygen chamber. It may help athletes improve endurance, measured by their breathing and fitness performance.
ZrifinAges 18–45
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Common questions
- Are there clinical trials for oxygenation?
- Yes. Clin2 currently lists 383 recruiting oxygenation studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a oxygenation trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a oxygenation trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.