Clinical trials · Ohio
Pain clinical trials in Ohio
We’re tracking 79 recruiting pain studies with a site in Ohio — including Phase 1, Phase 2, Phase 3 and Phase 4 studies, each written for real people, not researchers.
Recruiting studies in Ohio
- NCT04883411Recruiting
First-in-human test of new cervical spine plate and cage
This study tests a new implanted metal plate and cage to treat problems in the neck caused by worn spinal discs and nerve or spinal cord compression. It is aimed at people whose symptoms have not improved with non-surgical care for at least 6 weeks (or who have worsening nerve/spinal cord symptoms).
Cleveland, OhioAges 22–79 - NCT07174440Recruiting
Testing numbing medicine for spine surgery
This trial is testing a numbing medicine placed near the spine (erector spinae block) during lumbar spine fusion surgery. It aims to see if it helps control pain and may reduce the amount of anesthetic needed during the procedure.
Cleveland, OhioAges 21–75 - NCT07026786Recruiting
Mindfulness for recovery after colorectal surgery
This study tests whether adding mindfulness sessions to your standard recovery plan helps you heal better after bowel surgery. You'll use a phone or tablet app to guide your mindfulness practice during your hospital stay.
Cleveland, OhioAges 18 years+ - NCT07016581Enrolling by invitation
Best length for a spinal cord stimulation test
This study is testing how long a spinal cord stimulation trial should last to best diagnose whether it will help your chronic pain. It compares different trial lengths to see which one gives the most accurate result.
Columbus, OhioAges 18 years+ - NCT06994442RecruitingPhase 3
Best pain relief for children on a breathing tube
This study tests adding extra pain medicines (acetaminophen or an NSAID) to usual opioid pain treatment for children on a breathing machine. The goal is to find the safest and most effective way to manage pain.
Columbus, OhioAges 2 months–17 years - NCT06992427RecruitingPhase 3
Gabapentin to prevent opioid use for mouth pain during cancer treatment
This trial tests if taking gabapentin during chemoradiation for head and neck cancer can reduce the need for strong painkillers like opioids. It may help manage mouth pain caused by treatment.
Canton, OhioAges 18 years+ - NCT06957990Enrolling by invitation
Music therapy during hernia surgery to reduce pain medication
This study tests if listening to music therapy before and during hernia surgery can lower the need for strong painkillers (narcotics). It may help you manage pain with less medication.
Cincinnati, OhioAges 18 years+ - NCT06908538Recruiting
Cryo nerve block for pain after amputation
This study is testing a treatment called a cryo nerve block to reduce pain after amputation, including phantom limb pain. It will look at whether freezing the nerve during surgery helps people feel less pain and use less pain medicine.
Columbus, OhioAges 18 years+ - NCT06884865RecruitingPhase 2
Study of an experimental knee injection for osteoarthritis pain
This study tests a new investigational medicine injected into the knee to see if it is safe and tolerable for people with painful knee osteoarthritis. It may help reduce pain and improve knee function.
Dayton, OhioAges 45–80 - NCT06721819RecruitingPhase 3
Sleep and brain training before heart surgery to prevent delirium
This study tests whether a combination of sleep therapy, brain games, and light exercise before heart surgery can help prevent confusion or disorientation (delirium) after the operation. Participants will be asked to use a tablet and fitness tracker daily for about an hour before their surgery.
Columbus, OhioAges 60 years+ - NCT06691867Recruiting
Integrative training for sickle cell pain in teens
This study tests an integrative training program designed to help adolescents with sickle cell disease manage their pain better. It combines physical and mental techniques to reduce pain and improve quality of life.
Cincinnati, OhioAges 12–18 - NCT06671002RecruitingPhase 4
Pain medicine safety study for kids having surgery
This study compares different pain medicines to see which works best and is safest for children after surgery for tonsil removal, gallbladder removal, or knee arthroscopy. It aims to help find the most effective and least risky pain control option.
Columbus, OhioAges 12–20 - NCT06425016Recruiting
Robot-assisted vs. traditional sleeve gastrectomy
This study compares two types of weight-loss surgery: one done with the help of a robot and the other done by hand (laparoscopic). Both are types of sleeve gastrectomy, where the stomach is reduced in size. If you qualify for sleeve gastrectomy, this trial may help doctors learn which method works better.
Cleveland, OhioAges 18–70 - NCT06366269Recruiting
Acupuncture first for bladder pain syndrome
This trial tests whether acupuncture can help relieve pain and pressure from bladder pain syndrome (also called interstitial cystitis). Researchers want to see if using acupuncture early can improve symptoms better than usual care.
Cleveland, OhioAges 18–89 - NCT06350409Recruiting
Opioid use after surgery in teens
This study looks at how teens aged 12–17 use opioids after a scheduled surgery. It aims to understand outcomes and help improve pain management.
Cincinnati, OhioAges 12–17 - NCT06212661Enrolling by invitation
Study on migraine drugs and bladder symptoms
This study looks at how certain migraine treatments affect bladder symptoms like frequent or urgent urination. If you have hard-to-treat migraines and are starting a CGRP inhibitor or Botox injections, you may be able to join.
Cleveland, OhioAges 18 years+ - NCT06223659RecruitingPhase 2
EMLA cream for pain during lymphoscintigraphy for skin cancer
This trial tests whether EMLA cream can reduce pain from injections needed to map lymph nodes for certain skin cancers. If you are scheduled for lymphoscintigraphy and sentinel lymph node biopsy, you may be eligible.
Columbus, OhioAges 18–99 - NCT06184945Recruiting
Behavioral and staffing strategies in the ICU
This study tests different ways of organizing care and supporting patients in the intensive care unit (ICU) to see if they can improve recovery and well-being. It focuses on adults who need a breathing tube and are in the ICU for at least a day.
Columbus, OhioAges 19 years+ - NCT05979493RecruitingPhase 4
Nerve block for pain after fibroid surgery
This study tests whether a nerve block (QL block) can help with pain after surgery to remove uterine fibroids while keeping the uterus. It may be a good option if you are having a laparoscopic myomectomy and want to manage pain without strong opioids.
Beachwood, OhioAges 18–45 - NCT05688904RecruitingPhase 1
Topical imipramine with light treatment for skin pain relief
This Phase 1 study tests whether applying imipramine cream to the skin affects pain and effectiveness when combined with a light-based skin treatment (photodynamic therapy). It’s mainly looking at safety and early signs of benefit for people with certain sun-damaged skin areas.
Fairborn, OhioAges 18 years+ - NCT05437575RecruitingPhase 3
Testing pain medicine given before arrival to a trauma center
This study tests whether giving pain medicine soon after an injury (before you reach the trauma center) improves comfort and care. You might be eligible if you’re transported to a participating trauma center and meet specific shock and pain levels.
Cincinnati, OhioAges 18 years+ - NCT05444361Enrolling by invitation
Ultrasound freezing treatment for pain after mastectomy
This trial tests a “freezing” nerve procedure guided by ultrasound to help reduce pain after mastectomy. It aims to lessen postoperative pain by temporarily calming specific nerves involved in chest wall sensation.
Cleveland, OhioAges 18 years+ - NCT05245695Recruiting
Endometriosis test using deep computer learning during surgery
This trial studies whether a computer (deep neural network) can better identify endometriosis in people with long-lasting pelvic pain using information from surgery. It may help doctors sort who has endometriosis more accurately when surgery is already planned.
Cincinnati, OhioAges 14–50 - NCT05110989Recruiting
Registry study of pain relief after freezing intercostal nerves
This study collects real-world information about how well freezing (cryoablation) of the intercostal nerves helps with pain after a procedure. It may help doctors understand outcomes and improve care for future patients.
Cincinnati, OhioAges 12 years+
Pain trials by city in Ohio
Where these studies are running in Ohio
Institutions with a site for the recruiting pain studies listed above.
- The Ohio State University · 6 studies
- Cleveland Clinic · 3 studies
- Cincinnati Children's Hospital Medical Center · 2 studies
- University Hospitals Cleveland Medical Center · 2 studies
- Aultman Health Foundation
- Cleveland Clinic, Main Campus
- META Medical Research Institute
- Nationwide Children's (NCH)
What taking part in a pain study involves
A screening visit first
Before anything else, the study team checks whether you fit — usually a visit with some tests. You can stop at any point, and screening is typically free.
Care at a nearby site
Study visits happen at a clinic or hospital taking part. Many studies cover the cost of the study treatment and related visits, and some reimburse travel.
You stay in control
Taking part is voluntary and you can leave a study at any time, for any reason, without affecting your regular care.
The team decides eligibility
Our fit check is a helpful first read, not a decision. The study team makes the final call after reviewing your health history.
Pain trials in other states
Common questions
- Are there pain clinical trials in Ohio?
- Yes. We're currently tracking 79 recruiting pain studies with a site in Ohio, each rewritten in plain language so you can see what it's testing and who it's for.
- How do I find out if I qualify for a pain study in Ohio?
- Each study lists its eligibility rules — age, diagnosis, prior treatments. On every trial page we explain these in plain language and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Do I have to live in Ohio to take part?
- Not necessarily. These studies have a site in Ohio, but eligibility is about your health, not your address — some people travel to take part, and a few studies reimburse travel. The study team can tell you what's required.
- Does it cost anything to join a pain trial?
- Using Clin2 is always free. Many trials cover the study treatment and related visits; some reimburse travel. The study team explains exactly what's covered before you decide.
Not the right time?
New pain studies open in Ohio regularly. Set up a health profile and we’ll quietly watch for studies that fit you and email you when one opens.
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.