Clinical trials
Pain clinical trials
Below are recruiting pain clinical trials, each written for real people, not researchers. We’re tracking 3,263 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT06031571Recruiting
Cupping vs myofascial release for neck pain
This trial compares two hands-on treatments for long-term neck pain that isn't caused by injury or serious spine problems. It aims to see if dynamic cupping or myofascial release works better to relieve pain.
Qina, Qena GovernorateAges 18–40 - NCT05757609Recruiting
Brain stimulation therapy for chronic low back pain
This trial tests whether a non-invasive brain stimulation treatment can improve physiotherapy results for people with long-lasting low back pain. You may be asked to do questionnaires and follow a treatment plan, and some people may be able to reduce pain or improve function.
GenevaAges 18–65 - NCT05902234Recruiting
Using body maps to study children’s pain emotions
This study looks at how children with pain and their parents describe emotions connected to where it hurts using “body maps.” It may help researchers better understand emotional and pain experiences in families.
HelsinkiAges 10–80 - NCT05704751Recruiting
Test of targeted nerve stimulator placement for long-term back pain
This study tests a way to place and program a spinal cord stimulator to reduce long-term (chronic) back pain. It’s for people whose back pain has lasted at least 6 months and is severe enough to measure.
LondonAges 18–75 - NCT05812885Recruiting
TENS for long-lasting low back pain
This study tests whether transcutaneous electrical nerve stimulation (TENS), a non-drug pain treatment using small electrode pads on the skin, can help people with low back pain. You may be eligible if your back pain has lasted at least 3 months and your pain is at least moderate.
West Hartford, ConnecticutAges 18–60 - NCT05843890Recruiting
Personalized pain guide for chronic low back pain
This study tests a tailored (personalized) pain guide to help people with long-lasting lower back pain. It may help by teaching strategies to reduce how pain interferes with daily life.
Ann Arbor, MichiganAges 18 years+ - NCT05328401Recruiting
Laser acupuncture for shoulder pain after stroke
This trial tests whether laser acupuncture can reduce shoulder pain in people recovering from a stroke. It compares outcomes while making sure participants are not using certain pain medicines or shoulder injections that could affect results.
Keelung, TaiwanAges 20 years+ - NCT04853732Recruiting
Pain research registry for chronic low back pain
This study is a research registry that collects information from people with chronic low back pain (and some people without chronic pain). It may help researchers better understand pain patterns and guide future treatments.
Fort Worth, TexasAges 21–79 - NCT04936646Recruiting
Brain stimulation study for long-term nerve pain
This trial tests whether a form of brain stimulation (rTMS) can reduce chronic nerve pain that has lasted more than a year and hasn’t improved with standard treatments. It may help people whose usual pain medicines are stable but still not working well.
Grenoble, IsèreAges 18–80 - NCT04853173Recruiting
Testing pain-relief methods for adult tonsillectomy
This trial looks at how best to control pain for adults having tonsil removal (tonsillectomy) on an outpatient basis. It may help find a pain plan that works well and is safe for people like you.
BesançonAges 18 years+ - NCT04270617Recruiting
Yoga practice for long-term back pain
This study looks at whether regular yoga helps people with chronic (long-lasting) back pain. If you can safely take part in yoga sessions and your pain has lasted at least 3 months, you may be able to enroll.
New York, New YorkAges 18 years+ - NCT04104412RecruitingPhase 1
Stem cell injection study for long-lasting disc back pain
This Phase 1 study tests the safety and early effectiveness of an umbilical cord stem cell injection for people with persistent lumbar (lower back) disc-related pain that has not improved with standard care. If you qualify, it may offer a new treatment option, while researchers closely monitor side effects and pain changes.
Beijing, Beijing MunicipalityAges 18 years+ - NCT05484635Recruiting
Test removing mesh versus leaving it for groin pain
This study compares removing the pre-surgery mesh versus not removing it in people who have long-lasting groin pain after inguinal hernia repair. It may help doctors learn which approach best reduces ongoing pain.
Cleveland, OhioAges 18 years+ - NCT05354869Recruiting
Electrical stimulation therapy for pelvic floor muscle pain
This trial tests a treatment that uses gentle electrical stimulation through the vagina to reduce long-term pelvic pain caused by tight pelvic floor muscles. You might join if your pain has lasted over 6 months and exam shows specific muscle “trigger points.”
Los Angeles, CaliforniaAges 18–65 - NCT05265000Recruiting
Skin electrical stimulation for chronic low back pain
This study tests whether a gentle electrical treatment placed on the skin near the spine can reduce chronic low back pain. If you qualify, you’ll try the stimulation and complete several assessments over a day, so the team can measure any pain and function changes.
San Francisco, CaliforniaAges 21–85 - NCT05604066Enrolling by invitation
MRI scan to study muscle pain stiffness in low back or leg
This study uses a special MRI scan (magnetic resonance elastography) to measure how stiff muscles are in people with long-lasting low back or leg muscle pain. It may help researchers better understand myofascial pain—pain caused by tight, tender spots in muscle.
Rochester, MinnesotaAges 18 years+ - NCT04658628Recruiting
Brain scan study to learn who responds to spinal cord stimulation
This trial uses brain imaging to understand which people with long-lasting low back pain are more likely to benefit from spinal cord stimulation (SCS). If you’re being considered for an SCS trial, the scans may help researchers predict response and improve future care.
Los Angeles, CaliforniaAges 21 years+ - NCT07158736Recruiting
Nerve block for knee pain in the emergency room
This trial tests whether a nerve block can reduce knee pain in the emergency room. If you have knee pain without an injury and are at least 18 years old, this treatment may offer quick relief.
Philadelphia, PennsylvaniaAges 18 years+ - NCT03168802Recruiting
Ultrasound and nerve treatment for facet-joint low back pain
This study tests whether a procedure that uses focused ultrasound (MRgFUS) and/or a radiofrequency nerve treatment can reduce long-lasting low back pain caused by facet-joint arthritis. It may help people whose pain improves strongly after a targeted numbing injection to specific back nerves.
Taipei, Please SelectAges 20–79 - NCT07120659Recruiting
Comparing vacuum and tactile massage for chronic neck pain
This study compares two types of massage (vacuum massage and tactile massage) to see which one works better for people with long-term neck pain. If you have had neck pain for at least 3 months, you may be able to join.
Tromsø, TromsAges 21–75 - NCT06467747Recruiting
Music therapy for pain during surgery recovery
This trial studies whether listening to music can help reduce pain and improve recovery after common laparoscopic surgeries. It is for adults having gallbladder or appendix removal as same-day surgery.
Taichung, Not in USAAges 20–80 - NCT06490484RecruitingPhase 2
A new capsule for diabetic nerve pain when pregabalin doesn't work
This trial tests an experimental drug (HSK16149) for people with long-term diabetic nerve pain that hasn't been helped enough by pregabalin. It aims to see if the new capsule can reduce pain more effectively.
Hangzhou, ZhejiangAges 18–75 - NCT06517342Recruiting
Using a health app for low back pain
This study looks at what helps or stops people with chronic low back pain from using a smartphone app to become more active. It aims to find ways to make it easier for you to stay active.
Clermont-FerrandAges 18 years+ - NCT07655349Recruiting
Comparing two ways to attach gum grafts after surgery
This study tests if using small titanium tacks to hold a gum graft in place causes less pain than the usual stitches. It might help people who need more attached gum around their teeth.
Cairo, Cairo GovernorateAges 18 years+
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Common questions
- Are there clinical trials for pain?
- Yes. Clin2 currently lists 3,263 recruiting pain studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a pain trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a pain trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.