Clinical trials
Pain clinical trials
Below are recruiting pain clinical trials, each written for real people, not researchers. We’re tracking 3,263 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT06262126Recruiting
Virtual reality for non-cardiac chest pain
This study tests whether virtual reality can help people who have chest pain that is not caused by the heart. You will use a VR headset to see if it reduces your symptoms.
Jacksonville, FloridaAges 18 years+ - NCT06263907Recruiting
Nerve block to prevent depression after mastectomy
This study tests whether a nerve block near the neck (stellate ganglion block) can help prevent depression after mastectomy for breast cancer. It is for women who are generally healthy and have no history of mood disorders.
Al MansurahAges 21–65 - NCT06268964RecruitingPhase 1/Phase 2
Trimebutine vs probiotics for kids with belly pain
This study compares two treatments—trimebutine and probiotics—to see which works better for children with recurring stomach pain that has no clear medical cause. It aims to find a safe and effective option for kids aged 4 to 18.
ColimaAges 4–18 - NCT06271174RecruitingPhase 3
Preventing long-term pain after child surgery
This study tests whether a pain block (medicine injected near nerves) can prevent long-term pain after a child's bone or joint surgery. It aims to help children have less pain months later.
NantesAges 5 years–15.3 years - NCT06271447Recruiting
Pain questionnaire study for chronic low back pain
This study looks at how well pain questionnaires measure changes in chronic low back pain over time. If you have had long-term low back pain, researchers want to see if these surveys can accurately detect meaningful improvements.
Istanbul, None SelectedAges 18–65 - NCT06273462RecruitingPhase 2
Testing PEA for Chronic Inflammatory Pain
This study tests a natural supplement called palmitoylethanolamide (PEA) to see if it can help people with long-term inflammatory pain that hasn't gotten better with other treatments.
San Diego, CaliforniaAges Any age - NCT06281431Recruiting
Study comparing two needle types for nerve blocks to reduce pain
This trial compares a special echogenic (ultrasound-visible) needle with a standard needle for nerve blocks during surgery. The goal is to see which works better for preventing both short-term and long-term pain after operations like chest, abdomen, or limb surgeries.
Chongqing, Chongqing MunicipalityAges 18–70 - NCT06281275Recruiting
Frailty and pain after chest surgery in older adults
This study looks at how frailty affects pain after chest surgery in patients aged 60 and older. It uses a special pain pump and may help doctors better manage recovery for older adults.
Wuhan, HubeiAges 60 years+ - NCT06282770Recruiting
Light therapy belt for lower back pain after spine surgery
This trial tests whether a special light therapy belt can help reduce long-term lower back pain you still have 1 to 5 years after spinal fusion or decompression surgery.
Los Angeles, CaliforniaAges 18–75 - NCT06283199Recruiting
Tracking pain reports with a smartphone app
This trial compares pain reports recorded in real time using a smartphone app to those collected during monthly clinic visits. It aims to understand if daily tracking gives a more accurate picture of symptoms for people with musculoskeletal conditions.
BolognaAges 18 years+ - NCT06287788Recruiting
Mouth soreness trial for nasopharyngeal cancer patients
This trial tests a new way to map mouth and throat sores caused by radiation therapy. It focuses on pain when swallowing to guide treatment, which may help reduce discomfort during cancer treatment.
Guangzhou, GuangdongAges 18 years+ - NCT06290011Recruiting
Mixed reality for chronic pain relief
This study tests a new therapy that uses mixed reality (a type of glasses that shows virtual images over the real world) to help distract you from pain and teach relaxation. It may help people with chronic pain who have not tried VR or MR before.
Shanghai, YangpuAges 18–85 - NCT06290661Recruiting
Nerve stimulation for shingles-related nerve pain
This study tests a treatment called peripheral nerve stimulation (using a small device to send mild electrical pulses) for people with nerve pain after shingles. It's designed for those whose pain is not well managed by usual treatments.
Wuhan, HubeiAges 18 years+ - NCT06296979Recruiting
Nerve stimulation for shoulder pain from liver or gallbladder issues
This study tests if stimulating a nerve in the neck can reduce right shoulder pain caused by liver or gallbladder problems. It may offer a non-drug option for managing this type of pain.
Seville, SevillaAges 18 years+ - NCT06303609Recruiting
Radiofrequency treatment for pelvic pain during sex
This study tests whether a special type of radiofrequency (a gentle heat treatment) can help women who have pain during vaginal penetration. You will not receive any other treatment for your pain during the study.
Salvador, Estado de BahiaAges 18–45 - NCT06306183Recruiting
Vitamin C for pain relief after an ER visit
This trial tests whether a high dose of vitamin C can help reduce pain for people who come to the emergency department with new muscle or bone pain. If you qualify, you will receive vitamin C or a placebo and track your pain over time.
Ottawa, OntarioAges 18 years+ - NCT06311240Recruiting
Chronic pain therapy in hemodialysis patients
This study looks at whether a certain kind of therapy can help people on dialysis who have chronic pain. If you have kidney failure and have been on hemodialysis for at least 3 months, you may be able to join.
Terrassa, BarcelonaAges 18 years+ - NCT06320041RecruitingPhase 4
Oliceridine for pain after orthopedic surgery
This trial tests a new painkiller called oliceridine for moderate to severe pain after orthopedic surgery. It may help you recover more comfortably with fewer side effects.
Yiwu, ZhejiangAges 18–100 - NCT07696286Recruiting
Alexithymia in chronic pain patients with a spinal cord stimulator
This study looks at a condition called alexithymia (difficulty identifying and describing emotions) in people who have chronic pain and a spinal cord stimulator. It aims to help doctors better understand how emotions affect pain treatment.
IstanbulAges 18 years+ - NCT06438471RecruitingPhase 1
Study of a new drug for nerve pain after spinal cord injury
This trial tests an experimental pill for people with spinal cord injury who have long-term nerve pain. It aims to see if the drug can reduce pain and be safe.
Augusta, GeorgiaAges 18 years+ - NCT06955221Recruiting
Alcohol injection for ovarian endometriosis pain
This study tests if injecting alcohol into ovarian endometriosis cysts can reduce pelvic pain and improve quality of life. It may offer a less invasive option for women with persistent cysts.
Palma de Mallorca, Balearic IslandsAges 18–45 - NCT06327542Recruiting
Group pain management in primary care clinics
This trial tests a group-based program to help people with chronic pain manage their symptoms. It is offered in primary care clinics that serve underinsured communities, and sessions are available in English or Spanish.
San Francisco, CaliforniaAges 18 years+ - NCT06330181Recruiting
Virtual walking therapy for spinal cord injury nerve pain
This study tests a new virtual reality walking therapy program designed to help people with incomplete spinal cord injury reduce nerve pain. If you use a wheelchair and have lasting nerve pain, this could be a way to try a non-drug treatment from home.
College Station, TexasAges 18 years+ - NCT06333353Recruiting
Can brain stimulation reduce endometriosis pain?
This study tests whether a gentle, non-invasive brain stimulation technique (repetitive transcranial magnetic stimulation, or rTMS) can reduce ongoing endometriosis-related pain. If you have persistent pelvic pain that hasn't improved with other treatments, this trial may offer a new option to explore.
Ottawa, OntarioAges 18–60
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Common questions
- Are there clinical trials for pain?
- Yes. Clin2 currently lists 3,263 recruiting pain studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a pain trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a pain trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.