Clinical trials
Pain clinical trials
Below are recruiting pain clinical trials, each written for real people, not researchers. We’re tracking 3,142 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT07072559Enrolling by invitation
Can a dental game reduce pain and anxiety during kids' pulp treatment?
This study tests whether playing a dental-themed game on a mobile device can help children aged 4 to 7 feel less pain and anxiety during a pulpotomy (a procedure to treat deep cavities in baby teeth). It aims to make the dental visit easier for kids who are cooperative but may be nervous.
Al MansurahAges 4–7 - NCT07071350RecruitingPhase 2/Phase 3
Optimizing heart rate for persistent concussion symptoms in military veterans
This trial tests a treatment designed to improve heart rate variability, which may help reduce long-term concussion symptoms like headaches, dizziness, and trouble sleeping. It is for military veterans who have had a mild concussion more than a year ago and still have ongoing symptoms.
Richmond, VirginiaAges 18 years+ - NCT07070245Enrolling by invitation
Comparing two therapies for plantar fasciitis pain
This study compares two hands-on treatments for plantar fasciitis: a technique using tools to massage the tissue and a method that involves holding the foot in a specific position. It aims to see which better reduces heel pain and improves movement.
Port Said, Port Said GovernorateAges 30–50 - NCT07067580Recruiting
Breathing exercises after transplant: pain and recovery
This trial tests if simple breathing exercises can reduce pain and improve recovery after an organ transplant. If you are between 18 and 65, had your first transplant, and are willing to try gentle breathing techniques, you may be able to join.
AnkaraAges 18–65 - NCT06985849Recruiting
Gentle exercise for chronic low back pain
This study compares two gentle exercise programs (Feldenkrais and Otago) to see which one helps people with chronic low back pain and balance problems feel better and move more easily. It focuses on adults who have had pain for at least 3 months and have some trouble with balance.
LahoreAges 18–65 - NCT05152264Recruiting
TENS device study for endometriosis-related chronic pain
This study tests whether a skin-applied electrical nerve pain-relief device (TENS) can help with long-lasting pain from endometriosis. It mainly looks at people who have confirmed endometriosis and are on stable hormone treatment.
GothenburgAges 18–100 - NCT07059754Recruiting
Cooling treatment for chronic eye surface pain
This trial tests a cooling treatment (EyeCool) for people with long-term pain on the eye's surface. It looks at how the treatment affects the eye's surface structure and inflammation after standard care hasn't worked well enough.
Melbourne, VictoriaAges 22–90 - NCT07061769Enrolling by invitation
Using a gentle head device to help with nerve pain from chemo
This trial tests a low-intensity cranial PEMF device to see if it can reduce nerve pain caused by chemotherapy. Participants use the device at home and receive text messages to track their symptoms.
Newport Beach, CaliforniaAges 18–60 - NCT07057063Recruiting
Light therapy for knee pain and swelling
This study tests if light therapy can reduce knee pain and swelling (synovitis) caused by arthritis. If you have long-lasting knee pain and arthritis, this treatment might offer a non-drug option to help you feel better.
ShenzhenAges 40–80 - NCT07058220Recruiting
Neck training for neck pain relief
This trial tests whether special neck position-sense exercises can help people with general neck pain feel better. It may be a good option if you have neck pain without a specific injury.
GizaAges 25–45 - NCT07062757Enrolling by invitation
Massage and melatonin for jaw surgery recovery
This study tests whether combining gentle lymphatic drainage massage with melatonin can reduce pain and swelling after jaw surgery. If you are scheduled for jaw surgery for the first time and are otherwise healthy, you may be able to join.
Istanbul, FatihAges 16–55 - NCT07058376Enrolling by invitation
Herbal medicine for chronic low back pain
This trial tests whether a herbal medicine strategy can safely and effectively reduce chronic low back pain lasting over 3 months. It may be an option if your pain has been moderate to severe and you are looking for alternative treatments.
Seoul, Gangnam-GuAges 19–69 - NCT07055178Recruiting
Virtual reality for pain and anxiety during vasectomy
This study tests if using a virtual reality headset during a vasectomy can help lower pain and anxiety. It compares VR with standard care to see which works better for patients.
Winnipeg, ManitobaAges 18 years+ - NCT07057557Recruiting
Aloe vera vs paraffin dressing for skin graft pain
This trial compares aloe vera dressing with paraffin tulle dressing to see which one reduces pain better at the area where a skin graft was taken. If you need a skin graft and are not allergic to either dressing, this study may help find a gentler way to manage your pain.
Lahore, Punjab ProvinceAges 18–60 - NCT07058727Recruiting
Comparing agents for partial pulp treatment on tooth survival and pain
This trial tests different materials used to treat a small area of exposed tooth pulp after cavity removal in permanent teeth without pain or infection, to see which one helps the tooth survive and causes less pain afterward.
Adana, SarıçamAges 15–55 - NCT05841732Recruiting
Behavior program with exercise to prevent low back pain returning
This trial tests a phone-based behavior change exercise program to help stop low back pain from coming back. It is for people who recently recovered from a recent low back pain episode and can safely do exercises.
Setúbal, Setúbal DistrictAges 18–65 - NCT06502457Recruiting
Virtual reality hypnosis for labor pain
This study tests whether using a virtual reality hypnosis program can help manage pain during early labor in women with low-risk pregnancies. If you are in the beginning stages of labor and want a non-drug option for comfort, this might be for you.
AmiensAges 18 years+ - NCT06955117Recruiting
McKenzie vs manual therapy for low back pain
This study compares two physical therapy methods to see which works better for low back pain that has lasted more than 4 weeks. It could help you find a more effective treatment without surgery or strong medication.
Malakand, KPKAges 35–45 - NCT07049029Recruiting
Physical activity and pain resilience study for teens
This study tests if physical activity can help teenagers with chronic pain feel better and be more active. It may help you learn ways to manage pain.
Columbus, OhioAges 12–17 - NCT07048769RecruitingPhase 4
Pain relief shot for saline ultrasound of the uterus
This trial tests if a numbing injection in the cervix reduces pain during a saline ultrasound that checks the uterus and fallopian tubes. It might help make the procedure more comfortable for you.
Hartsdale, New YorkAges 18–50 - NCT07045116Recruiting
Electronic vs. standard syringe for kids' dental pain and anxiety
This study tests if an electronic syringe causes less pain and anxiety in children during a dental numbing shot compared to a conventional syringe. It is for healthy 6-8 year olds getting their first dental visit and who need a filling on a baby molar on each side of the mouth.
CairoAges 6–8 - NCT07054840Recruiting
Pain and walking learning in older adults
This study looks at how pain affects learning to walk on a special treadmill that moves each leg at a different speed. It's for healthy older adults who want to understand how pain might change the way they learn new walking patterns.
Newark, DelawareAges 55–90 - NCT07054450Enrolling by invitation
Assessment and rehabilitation for chronic pinched nerve in the neck
This trial tests a program of assessment and rehabilitation (including physical exercise and possibly a nutraceutical supplement) for people with chronic cervical radiculopathy — a pinched nerve in the neck causing pain, numbness, or weakness in the arm. It may help reduce pain and improve function without surgery.
CraiovaAges 50–79 - NCT07046143Enrolling by invitation
Spinal cord stimulation for nerve pain in the lower back
This trial tests a non-invasive treatment that uses mild electrical stimulation on the skin over the spine to help relieve nerve-related pain in the lower back. It may be an option for people with chronic nerve pain, with or without pain spreading down the leg.
Nanchang, JiangxiAges 18–80
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Common questions
- Are there clinical trials for pain?
- Yes. Clin2 currently lists 3,142 recruiting pain studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a pain trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a pain trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.