Clinical trials
Pain clinical trials
Below are recruiting pain clinical trials, each written for real people, not researchers. We’re tracking 3,263 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT06729151Recruiting
Botox vs. standard care for bladder pain and sexual health
This study compares the effect of Botox injections into the bladder versus standard care (without injections) on sexual function in women with bladder pain syndrome. It aims to see if Botox can improve both pain and sexual health.
Bethesda, MarylandAges 18–99 - NCT06743802RecruitingPhase 4
Coenzyme Q10 for pain after lung surgery
This trial tests if taking coenzyme Q10 before and after thoracoscopic lung surgery can reduce pain. It may help you recover more comfortably.
Chongqing, Chongqing MunicipalityAges 18–75 - NCT06745453Recruiting
Nerve block for back pain in the ER
This trial tests whether a numbing injection near your spine can quickly relieve sudden back pain that has lasted less than six weeks. If it works, it could be a fast, non-opioid option during an ER visit.
Chicago, IllinoisAges 18 years+ - NCT06747871Recruiting
Opioids, low nicotine cigarettes, and chronic pain study
This study tests if using cigarettes with very low nicotine can help people with chronic pain who are on buprenorphine for opioid use disorder. It aims to see if this approach reduces smoking and helps you think about quitting.
Durham, North CarolinaAges 21 years+ - NCT06750211Recruiting
Muscle techniques for chronic neck pain
This study tests two types of gentle muscle-relaxing techniques for long-term neck pain with forward head posture. It compares one technique alone versus the same technique combined with a specific exercise to see which works better.
LahoreAges 20–50 - NCT06756516Recruiting
Feldenkrais Method for balance and back pain relief
This trial tests if the Feldenkrais Method, a gentle movement therapy, can improve balance and reduce pain in people with long-term mechanical back pain. It may be a good option if you've had back pain for at least 6 months and it doesn't shoot past your knee.
GizaAges 18–45 - NCT06757491Recruiting
Low frequency brain stimulation for diarrhea-predominant IBS pain
This trial tests if a type of brain stimulation called low-frequency repetitive transcranial magnetic stimulation (lf-rTMS) can reduce belly pain in people with irritable bowel syndrome that causes diarrhea (IBS-D). It is a non-invasive treatment that uses magnetic pulses to target areas of the brain involved in pain perception.
Suzhou, JiangsuAges 18–75 - NCT06758050Recruiting
Core exercises for front knee pain
This study tests whether doing core exercises can help reduce knee pain in people with patellofemoral pain syndrome—pain at the front of the knee that comes on gradually. It is meant for young adults with a healthy weight who have had this type of knee pain for more than 3 months.
GizaAges 18–35 - NCT06758414Recruiting
CBT for chronic pain in veterans with serious mental illness
This trial tests a type of talk therapy called Cognitive Behavioral Therapy for Chronic Pain, designed for veterans with serious mental illness. It aims to help you manage back pain and improve your quality of life.
Baltimore, MarylandAges 18 years+ - NCT06759935Recruiting
Laser therapy for chronic shoulder pain due to rotator cuff inflammation
This study tests a special laser device to reduce shoulder pain caused by soft tissue inflammation. It's for people with ongoing shoulder pain from rotator cuff issues. The laser is used directly on the skin over the painful area.
SerrisAges 18 years+ - NCT06761989Recruiting
Comparing two ways to control pain after Whipple surgery
This study compares two ways to manage pain after a Whipple procedure: one is a shot of morphine into the fluid around the spine, and the other is a small tube placed under the skin at the surgical cut that delivers pain medicine continuously. The goal is to see which method provides better pain relief and recovery.
Seoul, SeoulAges 19 years+ - NCT06765278Recruiting
Nerve block comparison for shoulder surgery pain relief
This trial compares three different types of nerve blocks to manage pain after shoulder arthroscopy. The goal is to find which block works best for reducing pain and improving recovery.
CairoAges 18–70 - NCT06766240Recruiting
MRI for low back pain in middle-aged women
This trial is studying how well MRI can evaluate low back pain in women between 40 and 60 years old. It may help doctors better understand the cause of your pain.
SohagAges 40–60 - NCT06766916RecruitingPhase 2
Testing Crisugabalin for nerve pain after radiation
This trial tests a drug called Crisugabalin to see if it helps people with nerve pain caused by radiation treatment for head and neck cancer. The study aims to find a better way to manage this type of pain that does not go away.
Fuzhou, FujianAges 18 years+ - NCT06771492RecruitingPhase 3
Antibiotics for chronic back pain with Modic changes
This trial tests whether an antibiotic (amoxicillin) can reduce chronic low back pain in people who have a specific type of bone change (Modic type I) after a past herniated disc. If you qualify, you would receive either the antibiotic or a placebo (inactive pill) for several weeks.
Rotterdam, South HollandAges 18–65 - NCT06773715Recruiting
Virtual reality for pain from sickle cell disease
This study tests if using virtual reality (VR) can help children and teens with sickle cell disease feel better during a severe pain episode. You would use VR while in the hospital to see if it reduces your pain.
New Orleans, LouisianaAges 8–21 - NCT06774274RecruitingPhase 4
Ketamine for pain after major orthopedic surgery: drip vs. pump
This study tests two ways of giving a medicine called ketamine to control pain after major bone or joint surgery. One method is a steady infusion (drip) through a vein, and the other is a patient-controlled pump (PCA) that lets you press a button for more medicine when you need it.
Medellín, AntioquiaAges 18 years+ - NCT06776965Recruiting
Ultra-processed foods and rheumatic disease study
This study explores how eating ultra-processed foods affects people with chronic rheumatic diseases like rheumatoid arthritis, spondyloarthritis, or osteoarthritis. It aims to understand if diet plays a role in symptom management.
LyonAges 18 years+ - NCT06777771Recruiting
Reformer Pilates for first-time pregnant women
This trial tests if Reformer Pilates (a type of exercise using a special machine) helps first-time pregnant women stay healthy. If you are in your first pregnancy and between 11 and 22 weeks along, this may be a good fit for you.
Izmir, KonakAges 18–35 - NCT06777875Recruiting
How genes affect pain after surgery in children
This trial looks at how certain genes may affect how children feel pain after surgery. The goal is to understand if differences in your DNA can help doctors manage pain better for each child.
BeirutAges 8–18 - NCT06778460Recruiting
Esketamine and lidocaine for pain after liver surgery
This trial tests whether two medicines, esketamine and lidocaine, can reduce long-term pain after liver surgery and possibly improve survival. It is for people who are having a planned liver removal (hepatectomy).
Chengdu, SichuanAges 18–75 - NCT06779396RecruitingPhase 4
Scalp injection to reduce pain after brain surgery in children
This trial tests if injecting a mix of two medicines (triamcinolone and ropivacaine) into the scalp before brain surgery can lower pain in children afterward. It compares this to standard care to see if it helps kids recover more comfortably.
Beijing, Beijing MunicipalityAges 2–12 - NCT06779604Recruiting
Numbing medicine mix for arm surgery pain relief
This trial tests if adding two medicines, dexmedetomidine and dexamethasone, to the numbing shot around the arm's nerves can improve pain relief during and after upper arm or hand surgery.
Istanbul, UmraniyeAges 18–70 - NCT06784089Recruiting
Hip fracture type, nutrition and pain after surgery
This study looks at how a person's nutrition before hip surgery relates to their pain levels after surgery. It aims to help doctors improve recovery for older adults.
AnkaraAges 65 years+
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Common questions
- Are there clinical trials for pain?
- Yes. Clin2 currently lists 3,263 recruiting pain studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a pain trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a pain trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.