Clinical trials
Pain clinical trials
Below are recruiting pain clinical trials, each written for real people, not researchers. We’re tracking 3,142 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT06982456Enrolling by invitation
Manual therapy for neck pain in physiotherapy students
This study tests if manual therapy techniques help students with localized neck pain feel better. It focuses on pain in the upper shoulder muscle.
MurciaAges 18–40 - NCT06978816Recruiting
Ear pressure points plus pain meds for kidney stone relief
This study tests whether pressing specific points on the ear, along with pain medicine, can relieve kidney stone pain faster than pain medicine alone. It's designed for people with confirmed kidney stones and moderate to severe pain who haven't taken pain relievers recently.
Shanghai, Shanghai MunicipalityAges 18–75 - NCT06978335Enrolling by invitation
Acupoint stimulation for better wound pain relief after surgery
This study tests if gentle stimulation of acupoints (like acupressure or a small device) can ease pain from a surgical wound. It is for adults who are having a surgery with a long incision and will be using a pain pump afterward.
Taipei, Peitou DistAges 18 years+ - NCT06905340Recruiting
Pain-guided opioid use during surgery with regional anesthesia
This trial uses a special monitor (NOL index) to help doctors give just the right amount of pain medicine during surgery. It is for people having trauma or orthopedic surgery who are also getting regional anesthesia.
HamburgAges 18 years+ - NCT06966557Recruiting
Nerve block for chronic jaw pain
This trial tests a nerve block treatment for people with long-term jaw pain that hasn't improved with other treatments. It aims to see if this injection can help reduce pain.
Haifa, NorthAges 18 years+ - NCT06963177RecruitingPhase 2
Study of GenSci048 for endometriosis pain
This trial tests a new drug called GenSci048 to see if it can reduce moderate to severe pain caused by endometriosis. It might be an option if you have regular periods and are willing to switch to only the pain relievers allowed in the study.
Beijing, Beijing MunicipalityAges 18–49 - NCT06968689Recruiting
Brain activity study for experimental and chronic pain
This study uses MRI and EEG to look at brain connections involved in pain. It may help us understand how the brain processes pain and could lead to better treatments.
Houston, TexasAges 18–60 - NCT06962982Enrolling by invitation
VR therapy for neck pain in computer users
This study tests if short-term virtual reality exercises and ergonomic training can reduce neck pain, improve neck movement and strength, and boost work productivity in people who use computers for long hours.
AjmanAges 18–60 - NCT06970028Recruiting
Sensation study in ADPKD patients
This study looks at how people with ADPKD (a kidney condition that causes cysts) sense touch and temperature on their skin. It will compare their results with those of healthy volunteers to better understand the condition and help future treatments.
LeuvenAges 12 years+ - NCT06963671Enrolling by invitation
Blood flow restriction therapy for ulnar-sided wrist pain
This study tests using a blood pressure cuff during hand therapy to see if it helps reduce ulnar-sided wrist pain and improve hand function.
Redwood City, CaliforniaAges 18 years+ - NCT06965452Recruiting
Embolization for back pain from worn-out facet joints
This study tests if a minimally invasive procedure, called trans-arterial embolization, can reduce low back pain caused by aging facet joints (facet arthropathy). It may help people who haven't found relief from other treatments like injections or nerve blocks.
Manhasset, New YorkAges 18–85 - NCT06955221Recruiting
Alcohol injection for ovarian endometriosis pain
This study tests if injecting alcohol into ovarian endometriosis cysts can reduce pelvic pain and improve quality of life. It may offer a less invasive option for women with persistent cysts.
Palma de Mallorca, Balearic IslandsAges 18–45 - NCT06960317Recruiting
Numbing injection for IUD placement pain
This study tests whether a numbing injection (lidocaine) in the cervix can reduce pain during IUD placement. It's for women who have never had a vaginal birth and are getting their first IUD.
La Jolla, CaliforniaAges 18–50 - NCT06957639Enrolling by invitation
Physiotherapy for chronic neck pain
This trial tests a physiotherapy program for people with neck pain lasting 3 months or longer. The goal is to see if it helps reduce pain and improve daily function.
Yozgat, YozgatAges 18–64 - NCT06957158Recruiting
How calcium levels affect pain after abdominal surgery
This study looks at whether calcium levels in your blood can affect how much pain you feel after abdominal surgery. It may help doctors manage pain better after surgery in the future.
Chongqing, Chongqing MunicipalityAges 18–70 - NCT06956508Enrolling by invitation
VR therapy to prevent phantom limb pain after amputation
This study tests whether using virtual reality (VR) daily in the hospital after a major amputation can help prevent phantom limb pain. You'll use a VR headset to do simple exercises that may keep your brain from sending pain signals to the missing limb.
Charlotte, North CarolinaAges 13 years+ - NCT06962306RecruitingPhase 4
Pain relief study for children having cleft palate surgery
This trial tests different ways to manage pain after cleft palate repair in young children. The goal is to find which approach works best to lower pain and improve recovery.
Durham, North CarolinaAges 6 months–4 years - NCT06949059RecruitingPhase 1/Phase 2
Hydromorphone for acute chest pain relief
This trial tests a quick-acting pain medicine (hydromorphone) given through a vein to treat severe chest pain. It may be an option for people experiencing acute pain who haven't been helped by other medicines.
Nanjing, JiangsuAges 18–64 - NCT06943898Recruiting
Core and Breathing Exercises for Chronic Low Back Pain
This study tests if core and breathing exercises can improve balance and body awareness in people with chronic low back pain. The exercises are gentle and focus on strengthening the muscles that support your spine.
Sivas, MerkezAges 18–65 - NCT06946290Recruiting
Nerve block for pain relief after heart surgery
This study tests a nerve block, called an intertransverse process block, to see if it helps people feel better and recover faster after heart surgery. The block is given during surgery to reduce pain.
Hong KongAges 18 years+ - NCT06944314Enrolling by invitation
Doctors' views on pain during flexible cystoscopy with local anesthetic
This trial asks doctors to rate how much pain they think male patients feel during a minimally invasive bladder exam. It aims to see if doctors' estimates of pain are accurate.
Istanbul, IstanbulAges 18 years+ - NCT06240299Recruiting
Neurofeedback for chronic pain in rheumatoid arthritis
This trial tests a brain-training technique called neurofeedback to see if it can help people with rheumatoid arthritis who also have chronic widespread pain. It uses a computer to show you your brain activity and teach you to control it, which may reduce pain.
Glasgow, ScotlandAges 18–75 - NCT06939257Recruiting
Hormone therapy and pain in gender diverse adults
This study looks at how gender-affirming hormone therapy affects pain in gender diverse (GM) adults. It may help understand whether these hormones change how you feel pain.
Kansas City, KansasAges 18–50 - NCT06937853Recruiting
Genes and painkiller response for tooth pain
This trial tests whether your genes affect how well a common painkiller (NSAID) works for tooth pain after a root canal procedure. It may help find the best pain relief for you.
Erzurum, ErzurumAges 18–65
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Common questions
- Are there clinical trials for pain?
- Yes. Clin2 currently lists 3,142 recruiting pain studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a pain trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a pain trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.