Clinical trials
Pain clinical trials
Below are recruiting pain clinical trials, each written for real people, not researchers. We’re tracking 3,263 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT07234396Recruiting
Animated video for kids having elbow pins removed
This trial tests whether watching a short animated video before getting metal pins removed from a broken elbow can help reduce pain and anxiety in children. It compares the video to the usual care, which is just talking to the child.
Karachi, SindhAges 4–12 - NCT07238478Recruiting
Supplement for menopause quality of life in postmenopausal women
This trial tests a dietary supplement to see if it can improve menopause-related symptoms, like hot flashes and joint discomfort, in healthy postmenopausal women.
Harrison, New YorkAges 50–70 - NCT07239427Recruiting
Brain stimulation with pain coping for fibromyalgia
This study tests whether a gentle electrical brain stimulation method (tDCS), combined with a pain coping program, can help reduce fibromyalgia pain. It compares two groups to see if adding brain stimulation makes the coping program more effective.
Valladolid, ValladolidAges 18 years+ - NCT07245121Recruiting
Sugar water injections for chronic knee arthritis pain
This trial tests whether injecting a sugar-water solution around the nerves of the knee can reduce chronic pain from osteoarthritis. It is for people with long-term knee pain, stiffness, and cracking who have not had recent knee treatments or surgery.
Athens, AtticaAges 38 years+ - NCT07245303Recruiting
How Light Affects Pain in Chronic Pain
This study looks at how different kinds of light might change pain levels in people with chronic widespread pain, like fibromyalgia. By using brain scans (MRI), researchers hope to find new ways to manage pain without medication.
Chapel Hill, North CarolinaAges 18 years+ - NCT07247552Recruiting
Personalized rTMS for chronic pain
This study tests if personalized repetitive transcranial magnetic stimulation (rTMS), a non-invasive brain stimulation technique, can help reduce chronic pain. It aims to find out if targeting specific brain areas based on your pain patterns works better than standard treatment.
GistrupAges 18–80 - NCT07247929Recruiting
Pain and swelling after third molar surgery
This trial compares two surgical methods for removing partially impacted wisdom teeth to see which causes less pain and swelling afterwards.
Islamabad, IslamabadAges 18–45 - NCT07248813Recruiting
Home-based rehab program for chronic low back pain
This trial tests a telerehabilitation program you can do from home using a smartphone or computer. It aims to improve function and reduce pain for people with chronic low back pain compared to usual care.
México, TexcocoAges 18–60 - NCT07250399Recruiting
Pain after root canal treatment with different tools
This trial compares two different ways of cleaning a tooth's root canal to see which causes less pain during and after treatment. It is for people with severe tooth pain in an upper premolar.
CairoAges 20–50 - NCT07250568Recruiting
Office exercise program for low back pain in workers
This study tests if a special office exercise program can help people with low back pain feel better, reduce stress, and improve their quality of life. It includes exercises and posture advice for people who work at computers.
Depok, West JavaAges 18–58 - NCT07164677Recruiting
Nerve block for pain after open-heart surgery
This study tests a nerve block (an injection near the back muscles) to see if it helps control pain after open-heart surgery. It might be a good option if you are having planned heart surgery through a cut in the middle of your chest.
SamsunAges 18–80 - NCT07253025Recruiting
Comparing Two Root Canal Fillings for Pain Relief
This study compares two types of root canal filling materials—a resin-based sealer and a bioceramic sealer—to see which one causes less pain after the procedure. If you have a tooth with a painful, infected nerve (irreversible pulpitis), this trial may help determine which filler offers better comfort.
Peshawar, Khyber Pakhtoon Khawa(KPK)aAges 17–70 - NCT07257744Recruiting
Pain management after open heart surgery: comparing three methods
This trial compares three ways to manage pain after open heart surgery to see which best prevents long-term chronic pain. It may help you decide with your doctor which pain control option is right for you.
Trabzon, TrabzonAges 18–85 - NCT07260656RecruitingEarly Phase 1
Capsaicin cream for diabetic nerve foot pain
This trial tests a new cream (Capsadyn®) made from chili pepper extract to see if it can reduce nerve pain in the feet caused by diabetes. If it works, it could offer a simple treatment you apply at home.
Roanoke, VirginiaAges 25–75 - NCT07262944Recruiting
Pain block study for ear surgery with rib cartilage
This study tests a pain-blocking injection during ear surgery to see if it helps reduce pain after the operation. It is for teenagers having ear reconstruction with rib cartilage at a specific hospital.
SeoulAges 13–18 - NCT07264309Recruiting
Pain relief options for women in early labor
This trial compares two pain relief methods during the first stage of labor: a combination of tramadol and paracetamol given through an IV, versus pethidine given as a shot. The goal is to see which works better and has fewer side effects.
AfulaAges Any age - NCT07266103Recruiting
Personalized brain stimulation for chronic pain study
This study tests whether personalized sessions of repetitive transcranial magnetic stimulation (rTMS), a non-invasive brain stimulation technique, can help reduce chronic pain. It aims to understand how this treatment works and how it might be tailored to individuals.
GistrupAges 18–80 - NCT07267793Recruiting
Long-term study of CartiPRO for knee pain
This trial tests a treatment called CartiPRO for knee pain caused by osteoarthritis or cartilage damage. It looks at how well the treatment works over a long period and is for people who have a certain type of knee pain that hasn't improved with other treatments.
Seongnam-si, Bundang-guAges 19 years+ - NCT07268495Recruiting
Lidocaine spray to reduce pain after fibroid surgery
This trial tests if spraying lidocaine (a numbing medicine) inside the belly along with lidocaine given through an IV can lower pain after surgery to remove uterine fibroids. It may help you have less pain and recover more comfortably.
Yinchuan, NingxiaAges 18–65 - NCT07269925Recruiting
How different electrical frequencies affect muscle strength and pain
This study tests whether changing the electrical frequency during a type of nerve stimulation (percutaneous neuromodulation) can improve muscle strength and reduce pain sensitivity in people with a hidden muscle knot (trigger point) in the shoulder blade area.
Krakow, PolandAges 18–65 - NCT07270406Recruiting
Healthy habits for better sleep in people with HIV and pain
This study tests a healthy behaviors program to help prevent insomnia in people with HIV who also have ongoing pain. If you have trouble sleeping and chronic pain, this program may help improve your sleep and well-being.
St Louis, MissouriAges 25–65 - NCT07270588Recruiting
MobACT: Online support for chronic pain
This trial tests an internet-based program to help people manage chronic pain. You participate from home using a computer or tablet.
BolognaAges 18 years+ - NCT07274215Recruiting
Nerve block injection for pain and nausea after sleeve gastrectomy
This study tests a special numbing injection (called a paragastric block) to see if it reduces pain and nausea after sleeve gastrectomy surgery. If you are having this weight-loss surgery, the injection might help you feel better and recover more comfortably.
IstanbulAges 18–65 - NCT07276542RecruitingPhase 2/Phase 3
Ketamine for phantom limb pain: a six-month outpatient study
This study tests whether ketamine, given as an outpatient treatment, can reduce phantom limb pain over six months. You would come to a clinic for multiple ketamine sessions, with at least a week between each session, and be followed for a year.
Sacramento, CaliforniaAges 18–65
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Common questions
- Are there clinical trials for pain?
- Yes. Clin2 currently lists 3,263 recruiting pain studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a pain trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a pain trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.