Clinical trials
Pain clinical trials
Below are recruiting pain clinical trials, each written for real people, not researchers. We’re tracking 3,263 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT07340970Recruiting
Sensory feelings during planned c-section
This study explores what sensations women feel during a planned cesarean delivery with spinal anesthesia. It may help understand how women experience touch, pressure, or other feelings during the procedure.
Vancouver, British ColumbiaAges 19 years+ - NCT06887608Enrolling by invitation
Partner-Assisted Rebozo for Birth Comfort
This study tests a partner-assisted rebozo technique — a gentle way to help ease pain and fear during labor. Your partner wraps a scarf around your belly and sways it rhythmically, with guidance from a nurse, to make you more comfortable.
Zeytinburnu, IstanbulAges 18 years+ - NCT07336303Recruiting
Ear acupuncture for thumb surgery pain
This study tests whether ear acupuncture (auriculotherapy) helps reduce pain after thumb arthritis surgery. If you're having this surgery and haven't tried ear acupuncture before, you may be able to join.
ParisAges 18 years+ - NCT06543004Recruiting
Comparing pain after root canal with two filling materials
This study is comparing two different materials used to fill the tooth after a root canal to see which one causes less pain afterward. If you need a root canal on a front tooth or a premolar and you don't have pain or swelling, this trial may help find the gentler option for you.
DohaAges 18–60 - NCT06359665Enrolling by invitationPhase 1
Oral curcumin for thumb arthritis pain
This trial tests whether an oral curcumin supplement can help reduce pain from thumb arthritis. If you are an adult with daily thumb pain of at least moderate severity and have not taken turmeric or blood thinners, this may be an option for you.
Charlottesville, VirginiaAges 18 years+ - NCT07090122Recruiting
Spinal tumor treatment: ablation plus radiation vs radiation alone
This study compares two treatments for cancer that has spread to the spine. One group receives radiofrequency ablation (a heat-based treatment to destroy tumor cells) plus bone strengthening, followed by radiation. The other group receives radiation alone. The goal is to see which approach better controls pain and prevents spine problems.
Minneapolis, MinnesotaAges 18 years+ - NCT06920095Enrolling by invitation
Relaxation exercises for better sleep and less pain in lymphoma
This trial tests if progressive muscle relaxation exercises can help lymphoma patients sleep better, feel less tired, and have less pain. You will be guided through simple exercises using your phone.
Küçükçekmece, IstanbulAges 18 years+ - NCT06931951Recruiting
Acupuncture with medicine for knee pain after a car accident
This trial tests a type of acupuncture that injects medicine into specific points (pharmacopuncture) to treat severe knee pain from a recent traffic accident. It looks at whether this treatment is safe and effective for people who are already in the hospital for their injury.
DaejeonAges 19–69 - NCT06529432RecruitingPhase 2
Study of a long-acting painkiller for lung surgery recovery
This trial tests a long-acting pain medication (bupivacaine liposome injection) to control pain after lung surgery done through a small cut. It may help you feel more comfortable and reduce the need for other pain medicines.
Shanghai, Shanghai MunicipalityAges 18 years+ - NCT06803485RecruitingPhase 4
Comparing two antidepressants for pain-related somatic symptom disorder
This trial tests whether venlafaxine or dosulepin works better for people whose main problem is pain from a condition called somatic symptom disorder. You may join if you are 18–65, have not recently taken similar medication, and do not have other serious health issues.
Bhubaneswar, OdishaAges 18–65 - NCT07588165Recruiting
Measuring Pain During Emergency Breathing Tube Placement
This study tests a pain-monitoring device during emergency anesthesia for stomach or abdominal surgery. Researchers want to see how well the device (called ANI) detects pain when doctors quickly put a breathing tube in your airway.
MonacoAges 18 years+ - NCT07289321Enrolling by invitation
Pain relief study for robotic prostate surgery
This trial tests if adding tramadol and magnesium to a local anesthetic (ropivacaine) improves pain control after robotic prostate removal. It may help reduce the need for strong painkillers after surgery.
Athens, AtticaAges 40–80 - NCT06805942Recruiting
Embolization for heel pain from plantar fasciitis
This study tests a minimally invasive procedure called embolization to reduce heel pain caused by plantar fasciitis. It blocks tiny blood vessels in the painful area, which may relieve pain and help you walk more comfortably.
Falls Church, VirginiaAges 22–100 - NCT07289776RecruitingPhase 1
Testing a new medicine in healthy volunteers
This first-in-human trial tests a new medicine called GRT7041 in healthy people to see how safe it is and how it works in the body. It helps doctors understand the right dose and any side effects before testing in patients.
ChristchurchAges 18–60 - NCT07283003Recruiting
Pain after ureter stone removal surgery study
This study looks at pain levels after a procedure to remove stones from the ureter (the tube connecting your kidney to your bladder). It may help find better ways to manage pain after surgery.
BadenAges 18 years+ - NCT07282522Recruiting
Sensory and function in cervical disc herniation
This study looks at how cervical disc herniation affects sensation and daily function. If you have had neck pain for at least 3 months and have been diagnosed with cervical disc herniation, researchers want to compare your results to people without neck pain.
Iğdır, IğdirAges 18–65 - NCT07347054Recruiting
Trigger point injection for shoulder arthritis pain
This study tests whether injecting a medication into painful knots in the shoulder muscle can reduce pain from shoulder arthritis. It may be a good option if you have had shoulder pain for at least 3 months and other treatments haven't worked well enough.
Beijing, Beijing MunicipalityAges 45 years+ - NCT07177027Recruiting
Breathing exercises and music for first-time mothers in labor
This study tests whether combining breathing exercises with listening to music during labor can help first-time mothers feel less pain, have more positive expectations, and feel more satisfied with their birth experience. If you join, you will practice breathing techniques and listen to music while in labor.
Uşak, UşakAges 18–35 - NCT07256691Recruiting
Bioceramic vs. resin sealer for root canal pain
This study tests two types of sealing materials used in root canals (a newer bioceramic one vs. a standard resin one) to see which causes less pain after treatment. If you have an infected, pain-free tooth that needs a root canal, this trial may help guide better care.
Lahore, Punjab ProvinceAges 18–55 - NCT06526572Recruiting
Pain measurement with brain waves in tooth infection
This trial tests a new way to measure pain from a tooth infection using brain wave recordings (EEG). It may help people whose numbing injection doesn't work well.
Cleveland, OhioAges 18–50 - NCT06534866Recruiting
Kinesio tape plus therapy for plantar fasciitis
This study tests whether adding kinesio tape (a stretchy therapeutic tape) to standard physical therapy can reduce heel pain, improve ankle motion, and help you walk better. It is for people with plantar fasciitis who haven't had recent injections or surgery.
Rawalpindi, Punjab ProvinceAges 20–40 - NCT06874452RecruitingPhase 4
Anti-anxiety pill for second cataract surgery
This study tests if giving the anti-anxiety pill alprazolam (XANAX) before your second cataract surgery helps reduce anxiety and improve satisfaction with the procedure.
TaipeiAges 18–80 - NCT07185594RecruitingPhase 2/Phase 3
Study of a new pain drug after abdominal surgery
This trial tests a new medication called HRS-2129 for managing pain after abdominal surgery. It is for adults who will have moderate to severe pain after their operation, and aims to see if the drug can help control that pain safely.
Zhengzhou, HenanAges 18 years+ - NCT06513208RecruitingPhase 4
Ketorolac for pain after lower back fusion surgery
This trial tests if a non-steroidal anti-inflammatory drug (NSAID) called ketorolac can help reduce pain after lower back fusion surgery. It is for people who are having elective surgery to fuse one or two bones in their lower back.
Towson, MarylandAges 18–85
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Common questions
- Are there clinical trials for pain?
- Yes. Clin2 currently lists 3,263 recruiting pain studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a pain trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a pain trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.