Clinical trials
Pain clinical trials
Below are recruiting pain clinical trials, each written for real people, not researchers. We’re tracking 3,142 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT07672873Recruiting
Steroid injection for tooth nerve pain during root canal
This trial tests whether a single injection of dexamethasone (a steroid) near the nerve of a painful lower molar can improve pain relief during a root canal. It's for people with severe tooth nerve pain who haven't taken pain meds recently.
IstanbulAges 18–65 - NCT07675473RecruitingPhase 4
Pain relief before lung nodule localization
This trial tests giving a pain medicine (parecoxib) before a CT-guided lung nodule procedure to see if it reduces pain during the treatment. It's for people with non-small cell lung cancer who need a wire placed in their lung before surgery.
Shanghai, Shanghai MunicipalityAges 18 years+ - NCT07679295Enrolling by invitation
Port needle change: pain, anxiety, and satisfaction
This trial tests if using a stress ball during port needle changes can help reduce pain and anxiety in cancer patients. It aims to improve comfort and patient satisfaction.
SanliurfaAges 18 years+ - NCT07672093Recruiting
Dry needling for forearm muscle knots
This study tests whether inserting a thin needle (dry needling) into a tight muscle knot in your forearm can help release it without causing pain. It's for healthy adults who have a non-painful knot in their dominant arm.
Reus, TarragonaAges 18–40 - NCT07677540Recruiting
Nerve blocks before chest surgery to prevent long-term pain
This study is looking at two different types of nerve blocks—one called an erector spinae block and one called thoracic epidural—given before chest surgery to see if either can help prevent long-term pain after the operation.
Kfar SabaAges 18–99 - NCT07673328Recruiting
Knee brace study for people with knee arthritis
This study tests a motorized knee brace for people with knee osteoarthritis. The brace helps support your knee as you walk, climb stairs, and go up and down ramps.
Ann Arbor, MichiganAges 18–85 - NCT07672418Recruiting
Pain relief after tonsil surgery: ibuprofen vs. ketorolac
This study compares two common pain relievers (ketorolac and ibuprofen) given after tonsil/adenoid surgery in teenagers. It aims to see which works better while keeping side effects low.
Houston, TexasAges 13–18 - NCT07674901Recruiting
Knee sleeve vs. no sleeve for chronic knee pain in older adults
This study tests whether wearing a fabric knee sleeve every day for up to 5 years helps reduce knee pain in people aged 50–64. It compares sleeve use to not using a sleeve to see if it makes a difference over time.
Springfield, MassachusettsAges 50–64 - NCT06562816RecruitingPhase 4
Comparing two pain relievers after root canal treatment
This study tests two different pain medicines (trypsin-chymotrypsin and naproxen sodium) to see which one works better for pain after a root canal. It may help you if you need a root canal and are generally healthy.
Karachi, SindhAges 18–45 - NCT06671743RecruitingPhase 3
Medication before root canal to reduce pain
This study tests whether taking a medication before a root canal can reduce pain afterward. It is for people who need a root canal on a lower back tooth that has a painful, inflamed nerve but no infection at the root tip.
AjmanAges 20–50 - NCT06639022Recruiting
Pain relief after cervical spine surgery
This study compares two types of nerve blocks to see which provides better pain relief after neck surgery. It looks for patients scheduled for a specific neck procedure called anterior cervical discectomy.
Altındağ, AnkaraAges 18–80 - NCT07668648Recruiting
Two nerve blocks for shoulder surgery pain relief
This study compares two types of nerve blocks to reduce pain after shoulder surgery. One block is placed near the neck (interscalene) and the other is placed further away (serratus posterior superior intercostal plane block). The goal is to see which works better and has fewer side effects.
Bursa, NilüferAges 18–75 - NCT07666646Recruiting
Nerve block comparison for lung function after gallbladder surgery
This trial compares two types of nerve blocks to see which one better preserves lung function after laparoscopic gallbladder removal. It may help patients recover breathing ability more quickly after surgery.
Kayseri, KocasinanAges 18–70 - NCT06675877Recruiting
Virtual reality for kids with kidney disease on dialysis
This study tests whether virtual reality (VR) can help reduce anxiety and depression in children with end-stage kidney disease who are on hemodialysis through an arteriovenous fistula. It may offer a fun, drug-free way to feel better during treatment.
TantaAges 8–18 - NCT07665086Enrolling by invitation
Isometric exercise for rheumatoid arthritis
This study tests whether simple isometric (holding still) exercises can help people with rheumatoid arthritis. The goal is to see if these exercises improve hand function and quality of life.
DenizliAges 18–65 - NCT06662617Recruiting
Numbing injections for pain after gallbladder surgery
This study tests whether two different numbing injections (M-TAPA and TAPB) placed before surgery can reduce pain after keyhole gallbladder removal, compared to standard care. If you qualify, the injections may help you feel less discomfort after the operation.
SivasAges 18–80 - NCT07655323Recruiting
RISS vs. ESP Block for Gallbladder Surgery Pain
This study compares two types of nerve blocks (RISS and ESP) to manage pain after gallbladder removal surgery. It aims to find which block provides better pain relief.
Bursa, NilüferAges 18–75 - NCT07659990Recruiting
Comparing two nerve blocks for mastectomy pain relief
This study compares two types of nerve blocks given before a mastectomy (breast removal surgery) to see which one provides better pain relief. If you are having a mastectomy on one side with lymph node removal, you may be able to join.
Bursa, NilüferAges 18–75 - NCT07655336Recruiting
Nerve block comparisons for lung-sparing chest surgery
This trial compares two types of nerve blocks to manage pain during and after a type of lung surgery that removes only part of the lung. It aims to find which block provides better pain relief and recovery.
Bursa, NilüferAges 18–75 - NCT07662629Recruiting
Hyperbaric oxygen and exercise for breast cancer pain
This study tests if adding hyperbaric oxygen therapy (breathing pure oxygen in a special chamber) to a gentle exercise program can help reduce bone, joint, or muscle pain caused by hormone therapy in older women who had breast cancer.
Dokki, Giza GovernorateAges 65–75 - NCT07658521Enrolling by invitation
Nerve blocks for pain after heart bypass surgery
This study tests whether adding two numbing injections (nerve blocks) to standard care provides better pain relief after heart bypass surgery. It is for adults having planned surgery and compares pain scores and recovery.
Cairo, Cairo GovernorateAges 18–75 - NCT07655271Recruiting
Pain, arm function, and anxiety after shoulder surgery for brachial plexus palsy
This study examines pain, arm function, and social appearance anxiety in adults who had shoulder tendon transfer surgery as children for brachial plexus birth palsy. It helps understand long-term outcomes after this specific surgery.
Istanbul, IstanbulAges 18–40 - NCT07659015Enrolling by invitation
Using a hand exercise tool during IV placement
This study tests if using a simple hand-extension rubber band during IV placement can help reduce pain or improve the procedure. It may be an option for right-handed adults getting an IV in specific arm veins.
Konya, MeramAges 18–65 - NCT07653490Recruiting
Two anesthesia methods for gallbladder surgery
This study tests whether a numbing injection in the back (erector spinae plane block) helps reduce anesthesia needs during gallbladder surgery. It compares two anesthesia methods to see which works better for pain control and recovery.
IstanbulAges 18–65
Hear when a new Pain trial opens
We’ll email you when one opens — at most once a week, no account needed, unsubscribe anytime.
Common questions
- Are there clinical trials for pain?
- Yes. Clin2 currently lists 3,142 recruiting pain studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a pain trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a pain trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.