Clinical trials
Pain clinical trials
Below are recruiting pain clinical trials, each written for real people, not researchers. We’re tracking 3,142 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT07513012Enrolling by invitation
Pain Relief Methods After Gallbladder Removal Surgery
This study compares two ways of numbing the abdomen during gallbladder removal surgery to see which one works better for pain relief. One method numbs one side of your belly, and the other numbs both sides.
Lahore, Punjab ProvinceAges 18–80 - NCT07511842Recruiting
Keeping Your Knee Still After Surgery to Reduce Pain
This study tests whether keeping your knee immobilized (held still) for 72 hours after knee replacement surgery helps reduce pain. Researchers will compare this approach to standard care to see if it makes recovery easier.
Sherbrooke, QuebecAges 18 years+ - NCT07512141Recruiting
Single vs. Double Drains After Breast Cancer Surgery
This study compares using one drain versus two drains to collect fluid after breast cancer removal surgery. The goal is to see which approach works better and causes fewer problems during recovery.
Karachi, SindhAges 18–70 - NCT07507799Recruiting
Comparing low vs standard dose block for gallbladder surgery
This trial tests two different amounts of a numbing medicine (local anesthetic) given during gallbladder removal surgery. The goal is to see if a lower dose works just as well for pain control.
El Fayoum Qesm, Faiyum GovernorateAges 18–65 - NCT07510269Recruiting
Nerve blocks for pain control during mastectomy
This study tests two different numbing shots for the chest wall to see which one provides better pain relief during and after mastectomy surgery.
Bursa, NilüferAges 18–75 - NCT06719180RecruitingPhase 4
Pain relief after a hysterectomy
This study tests if numbing the top of the vagina (vaginal cuff) with a local anesthetic can reduce the need for pain medicine after a hysterectomy done by laparoscopy (small cuts in the belly). If you are having this surgery for a non-cancerous condition or cancer, you may be able to join.
Flushing, New YorkAges 18 years+ - NCT06760884Recruiting
Pregnancy and jaw function study
This study looks at jaw joint function, oral habits, and pain in pregnant and non-pregnant women. It aims to understand how pregnancy might affect these issues.
TrabzonAges 18–45 - NCT07505797Recruiting
Ultrasound imaging study for suspicious breast lesions
This study is testing a new ultrasound device (ATUSA) to see how well it can image breast lesions that have been classified as suspicious (BI-RADS 4 or 5). If you have a recent finding that needs further evaluation, this research might help improve detection methods.
Sacramento, CaliforniaAges 18–94 - NCT07500012Recruiting
Ear nerve stimulation for breast cancer pain
This study tests whether gentle electrical stimulation of a nerve in your ear (called taVNS) can help reduce pain and improve symptoms for breast cancer survivors. You would need to have finished your main treatments, have ongoing pain, and be willing to provide stool samples and undergo brain scans.
Tallahassee, FloridaAges 18–79 - NCT07500558Recruiting
Ultrasound-guided nerve block for chronic migraine pain relief
This study tests two power levels of a pulsed radiofrequency treatment aimed at a nerve cluster behind your cheekbone to reduce chronic migraine pain. If you have frequent migraines that haven't responded well to two or more preventive medications, this could be an option for you.
MinyaAges 20–70 - NCT07504120Recruiting
Home Pilates for people with multiple sclerosis
This study tests whether doing Pilates exercises from home, through online video sessions, can improve physical and mental well-being in people with mild to moderate multiple sclerosis. If you are fairly mobile and not very active, this could be a gentle way to increase exercise and feel better.
Chicago, IllinoisAges 18 years+ - NCT07501767Recruiting
Online exercise program for remote workers with back or neck pain
This study tests if a physiotherapist-led online exercise program can help remote workers with back or neck pain caused by long hours of sitting. It may improve your posture and reduce discomfort.
IstanbulAges 18 years+ - NCT07506018Recruiting
MucoLock for mouth pain caused by stomatitis
This study tests a new mouth rinse, MucoLock, to see if it can help people with severe mouth pain (stomatitis). If you have burning or painful mouth sores that rate very high on a pain scale, this trial may offer a new treatment option.
Miami, FloridaAges 18 years+ - NCT07501416Recruiting
High-Intensity Laser for Shoulder Pain After Stroke
This study tests whether a high-intensity laser can safely reduce shoulder pain in people who have had a stroke. If you are between 30 and 75, had a stroke in the last 6 months, and have moderate or worse shoulder pain on your weak side, you may be able to join.
Kütahya, CenterAges 30–75 - NCT07502157Recruiting
Massage for pain and anxiety during first cancer infusion
This study tests whether massage therapy can help reduce pain and anxiety in people with gynecologic cancer who are getting their first infusion treatment. You may be eligible if you are about to receive your first infusion and haven't had any in the past 2 years.
Lexington, KentuckyAges 18–85 - NCT07502612Recruiting
Spinal cord stimulation medication tapering study
This study tests whether lowering pain medication can improve how well spinal cord stimulation works. It is for people who already take certain pain medicines and are scheduled to try a spinal cord stimulator.
WilrijkAges 18 years+ - NCT07489937Recruiting
Arm exercise effects on the shoulder tendon
This study compares how two different arm exercises affect the shoulder tendon (supraspinatus) in people with and without shoulder pain. It may help find better ways to exercise without causing injury.
Gainesville, FloridaAges 18–45 - NCT07495761Recruiting
Central sensitization signs in adults with autism
This study looks at whether adults with autism (without intellectual disability) experience central sensitization, a condition where the nervous system becomes overly sensitive to stimuli. It aims to understand how common this is and why it matters for treatment.
Grenoble, IsereAges 18 years+ - NCT07494214RecruitingPhase 1
Study on MDMA for pain relief in healthy people
This trial tests if a single dose of MDMA can reduce pain caused by heat or pressure in healthy volunteers. It aims to see if MDMA might help with certain types of pain that are hard to treat.
BaselAges 18–75 - NCT07496632Recruiting
Scalp Numbing for Brain Surgery: Pain and Stability Study
This trial tests whether a numbing injection around the scalp (called a scalp block) can help keep your blood pressure and heart rate stable during brain surgery and reduce pain after surgery. It is for people having a planned craniotomy (surgery that opens the skull) on the upper part of the brain.
DhakaAges 18–64 - NCT07494864Recruiting
Urinary tract health and microbiome study
This study looks at how bacteria and the immune system affect the lower urinary tract. It includes healthy volunteers and people with various urinary conditions, like infections or bladder pain.
Zurich, Canton of ZurichAges 18 years+ - NCT07493434Enrolling by invitation
Can essential oils help with migraine pain?
This trial tests if inhaling essential oils can reduce pain in people with migraine. You may join if you have migraines and are not allergic to essential oils.
São Paulo, São PauloAges 18–60 - NCT06649383RecruitingPhase 4
Virtual reality for relaxation during surgery
This trial tests if virtual reality (VR) can help people over 65 relax or manage pain without medication during surgery with local or regional anesthesia.
Alingsås, Västra Götaland CountyAges 65 years+ - NCT05697159Recruiting
7-tesla brain MRI to study how filgotinib eases RA pain
This trial uses a very high-strength brain MRI to understand how the RA medicine filgotinib may reduce pain. If you have active rheumatoid arthritis and can safely complete the scan, the study may help researchers better target pain relief in RA.
GlasgowAges 18–74
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Common questions
- Are there clinical trials for pain?
- Yes. Clin2 currently lists 3,142 recruiting pain studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a pain trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a pain trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.