Clinical trials
Pain clinical trials
Below are recruiting pain clinical trials, each written for real people, not researchers. We’re tracking 3,142 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT07481630RecruitingPhase 3
Testing a new medicine for weight loss and knee pain
This study tests if a new medicine called NNC0487-0111 can help people with extra weight and knee osteoarthritis lose weight and reduce knee pain. If you have knee pain most days and are willing to stop pain relievers for short periods, you may be able to join.
Phoenix, ArizonaAges 18 years+ - NCT06638645Recruiting
Hospital stay after keyhole lung surgery
This study looks at how long people stay in the hospital after keyhole surgery to remove a part of the lung. It aims to find out what affects recovery time.
BrugesAges 18 years+ - NCT07485803RecruitingPhase 4
Methadone for pain after knee replacement
This study tests whether methadone, a type of pain medicine, helps control pain better after knee replacement surgery. It is for people who have not used narcotics recently and are otherwise healthy.
Denver, ColoradoAges 21–75 - NCT07485387Recruiting
Korean cognitive aging study using smartphone app
This study looks at how thinking and memory change as people get older. It uses a smartphone app to track these changes over time in healthy older adults living in South Korea.
Seoul, Select One...Ages 60 years+ - NCT07485517Recruiting
Deep vs Moderate Muscle Block for Hysterectomy
This study compares two levels of muscle relaxation (deep versus moderate) during hysterectomy surgery to see which may be better for recovery. If you are a woman scheduled for a planned hysterectomy and are in generally good health, you might be eligible.
Menoufia, Eg.mnAges 18–60 - NCT07486232Enrolling by invitation
Neck pain relief with posture exercises and taping
This study tests whether combining postural exercises with taping can help people with long-term neck pain who work at a desk. It aims to find a simple way to reduce pain and improve comfort.
IstanbulAges 25–55 - NCT07487246RecruitingPhase 2
Pain relief study for abortion dilator placement
This study tests whether combining two medications (lidocaine and ketorolac) given as a shot around the cervix can help with pain when placing small sticks (dilators) to prepare for an abortion procedure. If you are 16–24 weeks pregnant and planning an abortion, this trial may help you feel less discomfort.
Chicago, IllinoisAges 18 years+ - NCT07486609Enrolling by invitation
Comparing tests for jaw joint pain diagnosis
This study compares two different ways to diagnose jaw joint (TMJ) problems: a jaw-motion analyzer and an MRI. It aims to see which method is more accurate for people with ongoing face or jaw pain.
CairoAges 18–50 - NCT07481864Recruiting
Early mental exercise after shoulder tendon repair
This study tests if a gentle, early mental exercise program helps improve shoulder recovery after a specific type of rotator cuff repair. It might be a good fit if you had surgery on two front shoulder tendons and are otherwise healthy.
Istanbul, TurkeyAges 30–65 - NCT06075004Recruiting
Hip pain relief study comparing two injection methods
This trial tests two ways to give pain medicine around the hip joint during surgery to see which provides better pain relief. It may help patients experience less pain after hip replacement.
Santiago, Santiago MetropolitanAges 18–80 - NCT07480278Recruiting
Pain relief after back surgery: two injections compared
This trial tests two different injection methods to see which one provides better pain relief after lower back surgery. If you are having a microdiscectomy, this study may help determine the best way to manage your post-operative pain.
Bursa, NilüferAges 18–65 - NCT06780904Recruiting
Dry needling plus stretching for neck pain relief
This study tests if combining dry needling with gentle stretching or muscle energy techniques works better for treating neck pain caused by muscle knots (trigger points). It aims to find a simple, effective way to reduce pain and improve movement.
Kandy, Central ProvinceAges 18–60 - NCT06779578Recruiting
Comparing two types of radiofrequency for trigeminal neuralgia
This study compares two treatments (bipolar vs monopolar pulsed radiofrequency) for people with trigeminal neuralgia that hasn't improved with medication. It aims to see which method provides better pain relief.
AlexandriaAges Any age - NCT07476040Recruiting
Better care for new stable chest pain
This trial tests a new way to manage stable chest pain that started recently. It aims to improve diagnosis and treatment for people suspected of having coronary artery disease.
AugsburgAges 30 years+ - NCT07478289RecruitingPhase 2
Radiation boost for painful spinal metastases
This trial tests a higher dose of radiation (a boost) to painful spots in the spine where cancer has spread. The goal is to see if it can better relieve pain and improve function.
Toronto, OntarioAges 18 years+ - NCT07479199Recruiting
Radiofrequency ablation and radiation for painful spine tumors
This trial tests a treatment that uses heat (radiofrequency ablation) and radiation to relieve pain from tumors in the spine. It may help if you have cancer that has spread to your upper or lower back and you have moderate to severe pain.
Chapel Hill, North CarolinaAges 18 years+ - NCT07473206Recruiting
Laughing gas for pain during office hysteroscopy
This study tests whether using laughing gas (nitrous oxide) plus a calming video on a screen can reduce pain and anxiety during a quick procedure to look inside the uterus (hysteroscopy). If you are having this procedure, the trial may help you feel more comfortable.
BiellaAges 25–60 - NCT07472842Recruiting
Study on outcomes for endometriosis in emergency care
This study follows women who come to a specific hospital's emergency department with known endometriosis or symptoms that might be endometriosis, to learn more about their health outcomes over time.
CréteilAges 18 years+ - NCT07477847Enrolling by invitation
Custom exercise for back pain, posture, and quality of life
This study tests a personalized exercise program to see if it reduces back pain, improves posture (kyphosis angle), and boosts quality of life. It may help if you have nonspecific back pain and haven't been exercising regularly.
IstanbulAges 18–45 - NCT07472088Recruiting
Knee pain study using weight-bearing CT scans
This trial uses a special CT scan taken while you stand to see how the shape of your knee joint relates to your knee pain. It may help researchers better understand knee arthritis and front-of-knee pain.
Kansas City, KansasAges 18 years+ - NCT06784986RecruitingPhase 4
Low-pressure gas system for robotic prostate surgery
This trial tests whether a special gas system (Airseal) used with very low air pressure during robotic prostate removal surgery can help patients recover better. It compares this to standard methods for men with prostate cancer.
Salvador, Estado de BahiaAges 18–65 - NCT04814082Recruiting
Compare two knee implant types for walking and function
This study compares two designs of knee replacement implants to see how they affect walking, function, and outcomes after surgery. You may be randomly assigned to one of the implant types used for your specific, approved knee replacement.
Baltimore, MarylandAges 18–75 - NCT07464080Recruiting
Brain imaging study for knee replacement patients
This study uses advanced brain scans to understand how pain and recovery change after knee replacement surgery. It may help researchers develop better ways to manage pain after surgery.
Ottawa, OntarioAges 18 years+ - NCT07470021Recruiting
Numbing injection for pain relief after ankle surgery
This study tests whether a numbing injection around the ankle nerves before surgery can reduce pain and help you recover faster after ankle arthroscopy. It is for people having this keyhole surgery and staying in the hospital for a short time.
Hangzhou, ZhejiangAges 18–65
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Common questions
- Are there clinical trials for pain?
- Yes. Clin2 currently lists 3,142 recruiting pain studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a pain trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a pain trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.