Clinical trials
Parkinson Disease Dementia clinical trials
Below are recruiting parkinson disease dementia clinical trials, each written for real people, not researchers. We’re tracking 320 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT05288842Recruiting
Study spinal fluid and brain changes in dementia types
This study looks at spinal fluid and MRI results in people with Alzheimer’s disease, frontotemporal dementia, or normal thinking (controls). It aims to understand differences in brain-related cells and measure what might help explain or track these conditions.
LilleAges 40–85 - NCT04087031Recruiting
Tech-based rehab for early Parkinson’s symptoms in older adults
This trial tests an innovative, technology-supported rehabilitation program to help older adults with early-stage Parkinson’s disease improve daily function. It may be helpful if your symptoms are mild and your treatments have been stable for at least a month.
AnconaAges 65 years+ - NCT05658302Recruiting
Deep brain stimulation for Parkinson’s, using targeted stimulation
This study is testing a specific approach to deep brain stimulation (DBS) for people with Parkinson’s disease who are getting DBS surgery as part of routine care. It may help doctors learn whether circuit-based, more targeted stimulation is safe and useful for Parkinson’s symptoms.
Minneapolis, MinnesotaAges 21 years+ - NCT06316232RecruitingPhase 4
DBS and Levodopa for Freezing of Gait in Parkinson's
This trial tests whether increasing the dose of levodopa or adjusting deep brain stimulation (DBS) can help reduce freezing of gait in people with Parkinson's who already have good control of other symptoms. It aims to find the best way to manage this common and frustrating problem.
BolognaAges 18–80 - NCT06548256Recruiting
Probiotic for Parkinson's Symptoms
This trial tests whether a probiotic called Clostridium butyricum can help with both movement and non-movement symptoms of Parkinson's disease. It aims to see if improving gut health can ease symptoms.
Kaohsiung CityAges 20–90 - NCT06570421Recruiting
Nerve stimulation for Parkinson's and essential tremor
This study tests a non-invasive nerve stimulation device for reducing tremors in people with Parkinson's disease or essential tremor. It follows up participants from a previous trial to see if benefits last up to 24 months.
OstravaAges 18 years+ - NCT06909045Recruiting
Adaptive vs. regular deep brain stimulation for Parkinson's
This study compares two ways of using deep brain stimulation (DBS) — an adjustable ‘adaptive’ version that changes with your brain signals, versus the standard continuous setting. It aims to see which works better for people with Parkinson's disease who already have a specific type of DBS device.
LeuvenAges 18 years+ - NCT07097298Recruiting
Empathy and compassion study for Parkinson's patients and caregivers
This study explores empathy and self-compassion in people with Parkinson's disease and their caregivers. If you have mild to moderate Parkinson's and a caregiver at home, you and your caregiver may join together to help researchers understand how to better support both of you.
LuganoAges 50–80 - NCT03021031Enrolling by invitation
Deep brain stimulation for Parkinson’s patients
This trial studies a type of brain stimulation to help reduce symptoms in people with Parkinson’s disease. You may be able to join if you have Parkinson’s and are being considered for this treatment.
Minneapolis, MinnesotaAges 21 years+ - NCT07386015Recruiting
Study of freezing of gait in Parkinson's disease
This study looks at people with Parkinson's disease or similar conditions who have walking problems like freezing of gait (feet feeling stuck) or balance issues. Researchers want to learn more about what causes these symptoms and how they affect people over time.
Tianjin, Tianjin MunicipalityAges 30–85 - NCT07521384Enrolling by invitation
Real-World Study of Intranasal Cell Therapy for Brain Injuries
This study follows people who receive intranasal stem cell or exosome therapy (tiny packages from special cells) for brain or neurological conditions like stroke, brain injury, or cerebral palsy. Researchers track how well the treatment works by measuring inflammation markers in the blood and monitoring clinical improvements over time.
Monterrey, Nuevo LeónAges 4–80 - NCT07202494Recruiting
Brain aging and resilience MRI study
This study uses powerful MRI scans to understand how the brain ages and why some people stay healthy while others develop neurological diseases like multiple sclerosis or Alzheimer's. It compares healthy volunteers to people with certain conditions, and all participants get a detailed brain MRI.
MarseilleAges 18–90 - NCT06482268RecruitingPhase 1
Cell transplant for advanced parkinson's disease
This trial tests a new type of cell transplant for Parkinson's disease. The cells are made from stem cells and are meant to replace damaged brain cells that produce dopamine, which may improve your motor symptoms.
La Jolla, CaliforniaAges 40–75 - NCT06608355RecruitingPhase 1
Stem cell treatment for early-onset Parkinson's
This trial tests a new stem cell treatment called NouvNeu001 for people with early-onset Parkinson's disease. The goal is to see if it's safe and if it can help improve movement and daily life.
Wuhan, HubeiAges 18–70 - NCT06683378RecruitingPhase 1
Parkinson's study: nerve implant during DBS surgery
This trial tests if implanting a small piece of your own leg nerve into the brain can improve Parkinson's symptoms. It is done at the same time as deep brain stimulation (DBS) surgery.
Lexington, KentuckyAges 45–75 - NCT04888364Recruiting
French study following people with Parkinson’s and related conditions
This study follows people with Parkinson’s disease, certain Parkinson-like conditions, and some people at higher risk. It helps researchers learn how these illnesses start and progress, which may lead to better earlier detection and care.
ParisAges 10 years+ - NCT05182892Recruiting
Reducing speech side effects from DBS using speech recordings
This study tests whether automated analysis of your speech can help reduce speech problems caused by deep brain stimulation (DBS) in Parkinson’s disease. It may help your team adjust DBS settings to improve how you speak while keeping Parkinson symptoms controlled.
PragueAges 18 years+ - NCT06848192Recruiting
Parkinson's disease case-control study at Westlake University
This study compares people with Parkinson's disease to healthy volunteers, looking at possible links between the gut and Parkinson's. If you have mild to moderate Parkinson's (or are a healthy match), you may help researchers understand what causes the disease.
Hangzhou, ZhejiangAges 50–75 - NCT07567599Enrolling by invitation
Deep Brain Stimulation Surgery for Parkinson's Disease
This study follows people with Parkinson's disease who are having a surgical procedure called deep brain stimulation (DBS), where thin electrodes are placed in the brain to help control movement symptoms. Researchers will track how well the surgery works and how it affects daily activities.
Belo Horizonte, Minas GeraisAges Any age - NCT06803823RecruitingPhase 2
Testing a new drug for agitation in Alzheimer's
This study tests an experimental drug, ONO-2020, to see if it can help reduce agitation in people with Alzheimer's disease. Agitation can include restlessness, pacing, or verbal outbursts, and this trial aims to find a new treatment option.
AichiAges 55–90 - NCT06304285Recruiting
Acupuncture for Parkinson's with chronic appendicitis
This trial tests whether acupuncture can help people with Parkinson's disease who also have chronic appendicitis. It aims to see if treating the appendix inflammation may also improve Parkinson's symptoms.
Hefei, AnhuiAges 40–70 - NCT07488364Recruiting
Understanding frailty in Parkinson's disease
This study looks at why some people with Parkinson's disease become physically frail. It aims to find factors that may help predict or prevent frailty.
Istanbul, TurkeyAges 40–85 - NCT05307055Recruiting
Testing brain effects after low-frequency stimulation in Parkinson’s
This study looks at how Parkinson’s disease symptoms and brain thinking (neurocognitive function) may change after low-frequency stimulation from an implanted brain device. It may help researchers understand whether this specific stimulation pattern could improve thinking or brain-related symptoms.
Los Angeles, CaliforniaAges 18 years+ - NCT05626608Recruiting
Directional brain stimulation for Parkinson’s tremor and movement control
This trial tests a continuous electrical brain stimulation device placed in a deep brain area to help Parkinson’s symptoms—especially tremor and trouble with movement. It may help improve daily function and reduce periods when medicine does not work well.
Montpellier, FranceAges 18–70
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Common questions
- Are there clinical trials for parkinson disease dementia?
- Yes. Clin2 currently lists 320 recruiting parkinson disease dementia studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a parkinson disease dementia trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a parkinson disease dementia trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.