Clinical trials
Parkinson Disease, Idiopathic clinical trials
Below are recruiting parkinson disease, idiopathic clinical trials, each written for real people, not researchers. We’re tracking 208 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT07174310RecruitingPhase 3
Prasinezumab for early Parkinson's disease
This study tests a new medication called prasinezumab, given through a vein (IV), to see if it can slow the progression of early-stage Parkinson's disease. It is for people who are on only one Parkinson's medication and have not yet developed motor complications.
Birmingham, AlabamaAges 50–85 - NCT07567482Recruiting
Exoskeleton-Assisted Walking for Parkinson's and Aging
This study tests whether a wearable robotic exoskeleton (a powered leg device) can help people with Parkinson's disease and older adults walk better and stay active. Researchers want to see if this technology improves mobility and reduces fall risk.
Gatineau, QuebecAges 50 years+ - NCT06937034Recruiting
Study of foslevodopa/foscarbidopa for advanced Parkinson's
This study observes how well a new type of levodopa/carbidopa treatment works in real-world practice for people with advanced Parkinson's disease who are already using it. It aims to understand patient experiences and the support program offered by the drug maker.
Graz, StyriaAges 18 years+ - NCT06742450Recruiting
Comparing two ways to stimulate the brain for Parkinson's
This trial compares two methods of deep brain stimulation (constant current vs constant voltage) for people with Parkinson's who already have the device placed but haven't turned it on yet. The goal is to see which method works better.
BeijingAges 18–75 - NCT06701955Recruiting
Reliability of a Fluctuation Scale in Parkinson's
This study tests how consistently a new scale measures 'on-off' fluctuations in Parkinson's disease. If you experience motor fluctuations (times when your symptoms change) and are on stable medication, you may help validate this tool.
GrenobleAges 30–75 - NCT07536022Recruiting
At-Home Ear Stimulation for Walking and Balance in Parkinson's
This study tests a small device worn on your ear (called taVNS) that sends mild electrical signals to help improve walking and balance problems in Parkinson's disease. You'll use it at home, and researchers will track whether it helps you move better.
Charleston, South CarolinaAges 40–85 - NCT06324422Recruiting
Exercise for Parkinson's fatigue
This trial tests if a structured exercise program can reduce fatigue in people with Parkinson's disease. It may help you feel less tired and improve daily function.
Aarhus, Central JutlandAges 40 years+ - NCT06087926Recruiting
TMS for apathy in Parkinson's disease
This study tests whether a non-invasive brain stimulation treatment called TMS (transcranial magnetic stimulation) can help improve apathy, or loss of motivation, in people with Parkinson's disease. You must have had symptoms for at least 4 years and be on stable Parkinson's medications.
Chapel Hill, North CarolinaAges 55–80 - NCT01682668Recruiting
Deep brain stimulation study for Parkinson movement problems
This study looks at how deep brain stimulation (an implanted brain device) affects Parkinson’s symptoms, especially movement problems like freezing, slowness, or involuntary movements. It may help people whose symptoms are not fully controlled by standard Parkinson medicines.
Paris, PARISAges 18–70 - NCT05557864Recruiting
Brain scan study for Parkinson’s patients with deep brain stimulators
This study looks at how the location of a deep brain stimulator in Parkinson’s disease affects movement problems. It mainly uses advanced 7T brain imaging to compare brain activity and motor symptoms.
Minneapolis, MinnesotaAges 21–89 - NCT04799470Recruiting
Testing new brain-stimulation patterns for Parkinson’s with DBS
This study tests whether different deep brain stimulation settings can improve symptoms in people with Parkinson’s who already have an implanted DBS system in the subthalamic nucleus (STN). To join, you must already have the specific Medtronic device and show good brain signal and symptom response after surgery.
Omaha, NebraskaAges 19–80 - NCT07730073Recruiting
LSVT-LOUD therapy for voice and speech in Parkinson's disease
This study tests whether LSVT-LOUD, a speech therapy program, can improve voice, speech, and quality of life in people with Parkinson's disease who have voice or speech problems. Participants must be native Turkish speakers, aged 40-80, with mild to moderate Parkinson's.
Kâğıthane, IstanbulAges 40–80 - NCT07513441RecruitingPhase 1
Testing Lu AF28996 for Parkinson's disease motor fluctuations
This early-stage trial tests a new medication called Lu AF28996 in Chinese patients with Parkinson's disease who experience predictable on-off episodes (times when medication works well versus poorly). The study aims to see if this drug can help reduce those difficult off periods.
Beijing, Beijing MunicipalityAges 35–85 - NCT07774312Recruiting
Comparing tTIS treatment intervals to standard care for Parkinson's
This study compares different schedules of a non-invasive brain stimulation treatment (called tTIS) to standard medication for Parkinson's disease. It aims to find the best timing for tTIS to improve motor symptoms.
Shanghai, Shanghai MunicipalityAges 50–85 - NCT07485621Recruiting
Using brain signals to improve deep brain stimulation for Parkinson's
This study uses brain signals (called local field potentials) from the deep brain stimulation (DBS) device to see if they can predict how well the treatment is working. It aims to help doctors adjust DBS settings more precisely for people with Parkinson's disease.
Leuven, Vlaams-BrabantAges 18 years+ - NCT06688968Recruiting
Music, thinking, and memory in Parkinson's and Alzheimer's
This study looks at how music engagement affects thinking and memory in people with Parkinson's or Alzheimer's disease. It may help researchers understand how music can support brain health as we age.
Montpellier, HéraultAges 60 years+ - NCT04848077Recruiting
Smartphone exercise program for early Parkinson’s patients
This trial tests whether a motivating phone-based exercise plan can help people with early-stage Parkinson’s move more safely and consistently. You may qualify if you can walk on your own, understand Dutch, and are fairly inactive right now.
Nijmegen, GelderlandAges 18 years+ - NCT07398157Recruiting
24-hour adaptive deep brain stimulation for Parkinson's
This trial tests a new deep brain stimulation system that adapts in real time to improve symptom control over 24 hours, especially for people with daytime fluctuations or sleep problems despite standard DBS.
San Francisco, CaliforniaAges 18 years+ - NCT07610369RecruitingPhase 2
Psilocybin therapy for depression in Parkinson's disease
This study tests whether psilocybin (a psychedelic compound) combined with therapy can reduce depression in people with Parkinson's disease. If you have moderate-to-severe depression and Parkinson's, this trial may offer a new treatment option.
New Haven, ConnecticutAges 40–80 - NCT07316296RecruitingPhase 3
Testing a drug to reduce freezing of gait in Parkinson's
This trial tests whether atomoxetine, a drug that boosts a brain chemical called noradrenaline, can help reduce freezing of gait—a feeling of your feet being stuck to the ground—in people with Parkinson's disease. You would continue your usual Parkinson's medications during the study and undergo walking tests and brain scans to see if the drug helps.
Nijmegen, GelderlandAges 18 years+ - NCT04616508Recruiting
Online arm movement training for people with Parkinson’s
This study uses online tasks to look at how people with Parkinson’s control reaching movements. You may benefit by contributing to research that could improve understanding and future treatments for movement problems.
Newark, DelawareAges 18–85 - NCT06745011Enrolling by invitation
Parkinson's signs in people with nerve damage
This study looks for early signs of Parkinson's disease in people who have nerve damage in their hands and feet (polyneuropathy) with no known cause, along with drops in blood pressure when standing up. It aims to understand if these early symptoms might predict future Parkinson's.
Aarhus, JutlandAges 18–85 - NCT07580612Recruiting
Home-based AI system for detecting freezing of gait in Parkinson's
This study tests an artificial intelligence system that detects freezing of gait—sudden, involuntary pauses while walking—using sensors you wear at home. The goal is to better understand and eventually help manage this common Parkinson's symptom.
LeuvenAges 18 years+ - NCT05919160Enrolling by invitation
New tiny electrode to record brain activity during DBS
This study tests a high-density microelectrode that captures detailed brain recordings while surgeons place a deep brain stimulator for Parkinson’s disease. It may help doctors better locate the exact brain area to target during surgery.
Los Angeles, CaliforniaAges 18 years+
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Common questions
- Are there clinical trials for parkinson disease, idiopathic?
- Yes. Clin2 currently lists 208 recruiting parkinson disease, idiopathic studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a parkinson disease, idiopathic trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a parkinson disease, idiopathic trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.