Clinical trials
Parkinsonism clinical trials
Below are recruiting parkinsonism clinical trials, each written for real people, not researchers. We’re tracking 734 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT07432958RecruitingPhase 2
Study of AP-472 with levodopa for Parkinson's motor fluctuations
This trial tests an experimental drug called AP-472, taken alongside your regular Parkinson's medications, to see if it can reduce the amount of "OFF" time you experience each day when symptoms return between doses of levodopa.
Little Rock, ArkansasAges 30–80 - NCT07434089Recruiting
Walking therapy and gut health in Parkinson's
This trial tests how a special treadmill (C-Mill) training affects the connection between your brain and gut in Parkinson's disease. It may help improve walking and gut symptoms.
Messina, MessinaAges 40–70 - NCT07427498Recruiting
How beliefs affect hallucinations in Parkinson's disease
This study looks at how your past experiences and expectations might influence visual hallucinations if you have Parkinson's disease. It involves cognitive tests and compares people with and without hallucinations, as well as healthy volunteers.
GrenobleAges 18–85 - NCT04735627Recruiting
Real-time monitoring of levodopa levels in Parkinson’s
This study checks whether measuring levodopa (a Parkinson medicine) in real time can help better understand Parkinson medication effects. You may be asked to wear/perform study monitoring while taking your usual carbidopa/levodopa tablets.
San Diego, CaliforniaAges 40–85 - NCT07424924Recruiting
Walking, activity, and sleep study for Parkinson's
This study looks at how walking, daily activity, and sleep are connected in Parkinson's disease. It compares people with Parkinson's to healthy volunteers to understand these links better.
IstanbulAges 40–75 - NCT06615115Recruiting
Focus instructions for balance in Parkinson's rehab
This study looks at whether different types of instructions (like focusing on your movements) can help improve balance for people with Parkinson's. It might help you move better and feel more steady.
IstanbulAges 50–70 - NCT06129942Recruiting
Light therapy for Parkinson's disease
This trial tests whether regular light therapy can help people with Parkinson's disease. It is designed for patients whose symptoms are at a moderate stage and whose medication has been stable for a month or more.
Suzhou, JiangsuAges 50–80 - NCT07409207Recruiting
Brain signals and reward in Parkinson's surgery
This study looks at brain activity related to reward during deep brain stimulation (DBS) surgery to help us understand Parkinson's disease better. If you are having DBS surgery, your brain signals during the procedure may help researchers.
Nashville, TennesseeAges 40 years+ - NCT07404241Recruiting
Brain activity linked to movement and mood swings in Parkinson's
This study looks at brain signals related to motor and psychiatric changes in people with Parkinson's who are scheduled for deep brain stimulation (DBS) surgery. The goal is to better understand why symptoms fluctuate and how DBS may help.
GenevaAges 18–80 - NCT07402928Recruiting
Dopamine signals in health and Parkinson's
This study uses MRI scans to look at dopamine signals in the brain. The goal is to understand how Parkinson's affects these signals.
HvidovreAges 35 years+ - NCT07403539Recruiting
Speech learning and production in Parkinson's disease
This study looks at how people with Parkinson's disease learn and produce speech. It may help researchers understand how Parkinson's affects talking and how to improve communication.
Buffalo, New YorkAges 45 years+ - NCT07398157Recruiting
24-hour adaptive deep brain stimulation for Parkinson's
This trial tests a new deep brain stimulation system that adapts in real time to improve symptom control over 24 hours, especially for people with daytime fluctuations or sleep problems despite standard DBS.
San Francisco, CaliforniaAges 18 years+ - NCT07399496Recruiting
Fast TMS for apathy in Parkinson's disease
This study tests a faster version of TMS (transcranial magnetic stimulation) to see if it can help with apathy—low motivation and lack of interest—in people with Parkinson's disease. You will receive several TMS sessions each day over a short period, and the study team will check if your mood and motivation improve.
Charleston, South CarolinaAges 45–85 - NCT06161636Recruiting
Studying hand movement to diagnose Parkinson's early
This trial looks at how analyzing hand movements might help doctors tell the difference between Parkinson's disease and other similar conditions early on. It may help improve diagnosis so patients get the right care sooner.
Montreal, QuebecAges 50–75 - NCT06356662RecruitingPhase 1
Testing tenofovir for Parkinson's disease
This trial is testing if a medicine called tenofovir, usually used for HIV and hepatitis B, can help people with early-stage Parkinson's disease. It's for people who are under 65 and have no other major health issues.
Hangzhou, ZhejiangAges 18–65 - NCT07397377Recruiting
Brain stimulation for slow movement in Parkinson's
This study tests whether a gentle form of brain stimulation (called prTMS) can help improve slow movement in people with Parkinson's. You would come to the Danish Research Centre for Magnetic Resonance for several sessions. The goal is to see if this non-invasive treatment can make daily tasks a bit easier.
HvidovreAges 18–80 - NCT07390825Recruiting
Water therapy for daily living and movement in Parkinson's
This study tests if aquatic therapy (exercises in water) can improve walking, balance, posture, pain, and daily activities for people with Parkinson's. It aims to see if water-based exercise helps more than standard care.
Çankaya, AnkaraAges 40–80 - NCT07392411Recruiting
AI study of face and speech in Parkinson's disease
This study uses artificial intelligence to analyze facial expressions and speech patterns in people with Parkinson's disease, multiple system atrophy, or progressive supranuclear palsy. The goal is to find digital markers that may help track the disease.
Beijing, Beijing MunicipalityAges 15–75 - NCT07380737Recruiting
Walking Tall app for home exercise in Parkinson's
This study tests a smartphone app called Walking Tall that helps people with Parkinson's disease do walking exercises at home. It's looking for people who can walk on their own and are already in a specific rehab program.
Tel AvivAges 40–85 - NCT07382440Recruiting
Study of a Parkinson's treatment given under the skin
This study looks at how well a treatment called foslevodopa/foscarbidopa works for people with advanced Parkinson's disease. It is given as a shot under the skin (subcutaneous) and is already being used in clinics. The study will follow people who are already starting this treatment as part of their regular care.
Bonheiden, AntwerpenAges 18 years+ - NCT07381907Recruiting
Brain stimulation combined with Nordic walking for Parkinson's
This study combines a mild electrical brain stimulation (tDCS) with Nordic walking (walking with poles) to see if it helps improve walking and balance in people with Parkinson's disease. The treatment lasts 4 weeks and may be an option if you have a slow walking pace and no implanted brain devices.
Belém, ParáAges 50–75 - NCT07381751Recruiting
AI assessment of Parkinson's motor symptoms via video
This study uses artificial intelligence to analyze videos of standard motor tests (MDS-UPDRS Part III) for people with Parkinson's disease. It aims to see if AI can reliably assess your symptoms, which could lead to easier, more accessible monitoring in the future.
Hong KongAges 18–95 - NCT07376278Recruiting
Deep brain stimulation outcomes in Parkinson's disease
This study looks at factors that predict how well deep brain stimulation (DBS) works for people with Parkinson's disease. If you are considering DBS, joining this research could help doctors better understand who benefits most from the procedure.
Hong KongAges 18–75 - NCT07375693Enrolling by invitationPhase 2
Melatonin for Parkinson's patients on levodopa
This trial tests if adding melatonin can reduce oxidative stress (a kind of cell damage) in people with mild to moderate Parkinson's disease who are already taking levodopa. It aims to see if melatonin helps protect the brain and improve symptoms.
Dhaka, Dhaka DivisionAges 45–85
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Common questions
- Are there clinical trials for parkinsonism?
- Yes. Clin2 currently lists 734 recruiting parkinsonism studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a parkinsonism trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a parkinsonism trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.