Clinical trials
Parkinsonism clinical trials
Below are recruiting parkinsonism clinical trials, each written for real people, not researchers. We’re tracking 732 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT07523425Recruiting
Virtual Reality Movement Training for Parkinson's Disease
This study tests whether using virtual reality—either alone or with others—can help improve movement and balance in people with Parkinson's disease. You would participate in rehabilitation sessions using VR technology while your symptoms and mobility are monitored.
Lahore, Punjab ProvinceAges 45–80 - NCT07513441RecruitingPhase 1
Testing Lu AF28996 for Parkinson's disease motor fluctuations
This early-stage trial tests a new medication called Lu AF28996 in Chinese patients with Parkinson's disease who experience predictable on-off episodes (times when medication works well versus poorly). The study aims to see if this drug can help reduce those difficult off periods.
Beijing, Beijing MunicipalityAges 35–85 - NCT07514858RecruitingPhase 2
Lu AF28996 for Parkinson's Disease Motor Fluctuations
This trial tests a new medication called Lu AF28996 to help reduce the periods when Parkinson's symptoms worsen throughout the day (called 'OFF times'). If you have motor fluctuations that are predictable and affecting your daily life, this study might help you experience fewer of these difficult periods.
Farmington Hills, MichiganAges 40–85 - NCT07498296Recruiting
Adapting a home program and sleep tracking for Parkinson's
This trial tests a program to help people with Parkinson's disease exercise at home and improve sleep. It uses online coaching and a video device to see if it makes daily tasks easier.
Aurora, ColoradoAges 18 years+ - NCT06772220Recruiting
Homocysteine management for Parkinson's patients on levodopa
This trial tests whether controlling homocysteine levels can help people with Parkinson's disease who are taking levodopa. You may qualify if you take at least 300 mg of levodopa per day, are between 40 and 90 years old, and have no major kidney problems or uncontrolled high blood pressure.
Portland, OregonAges 40–90 - NCT06665113Recruiting
Ear nerve stimulation for early Parkinson's disease
This trial tests whether a non-invasive nerve stimulation device (taVNS) worn on the ear can protect brain cells and slow Parkinson's disease progression in early-stage patients. It is for people who have been diagnosed within the last 3 years and are already on standard medication.
Nanjing, JiangsuAges 55–75 - NCT07488377Recruiting
Cognitive Self-Confidence in Parkinson's Disease
This study tests a new questionnaire to measure how confident people with Parkinson's feel about their thinking and memory. It may help doctors better understand and support cognitive changes in Parkinson's.
Istanbul, TurkeyAges 40–85 - NCT07488026Recruiting
Brain stimulation for mobility in Parkinson's disease
This trial tests if a type of brain stimulation (transcranial magnetic stimulation) applied to different areas of the brain can improve walking and movement in people with Parkinson's disease. The goal is to see which stimulation site works best for reducing freezing of gait and improving daily mobility.
Recife, PernambucoAges 40 years+ - NCT07488364Recruiting
Understanding frailty in Parkinson's disease
This study looks at why some people with Parkinson's disease become physically frail. It aims to find factors that may help predict or prevent frailty.
Istanbul, TurkeyAges 40–85 - NCT07488351Recruiting
Self-kindness and confidence in Parkinson's: symptoms, function, quality of life
This study looks at how self-compassion and self-belief affect symptoms, daily function, and quality of life in people with Parkinson's disease. It aims to help researchers understand how emotional well-being relates to physical health.
Istanbul, TurkeyAges 40–85 - NCT07485621Recruiting
Using brain signals to improve deep brain stimulation for Parkinson's
This study uses brain signals (called local field potentials) from the deep brain stimulation (DBS) device to see if they can predict how well the treatment is working. It aims to help doctors adjust DBS settings more precisely for people with Parkinson's disease.
Leuven, Vlaams-BrabantAges 18 years+ - NCT07475741Recruiting
Exergaming for better arm and hand function in Parkinson's
This trial tests whether exergaming (video games that involve physical movement) can improve arm and hand function in people with early-stage Parkinson's disease. It may help you move better and do daily tasks more easily.
Lahore, Punjab ProvinceAges 45–85 - NCT07478146Recruiting
Aerobic exercise for brain and movement in Parkinson's
This study tests whether moderate aerobic exercise (like brisk walking or cycling) can improve thinking, memory, and walking ability in people with Parkinson's disease. It also looks at how exercise affects blood flow in the brain.
São Paulo, São PauloAges 40 years+ - NCT07465107Recruiting
Motor and cognitive exercise in Parkinson's
This study tests whether combining motor (physical movement) exercises with cognitive (thinking) exercises can help people with Parkinson's disease. It may improve both movement and thinking skills.
Copenhagen NVAges 18 years+ - NCT07467460Recruiting
Precision medicine trial for Parkinson's and Alzheimer's
This trial uses advanced tools to better diagnose and treat Parkinson's disease and Alzheimer's disease. It aims to personalize care based on your specific symptoms and biomarkers.
PozzilliAges 18 years+ - NCT07461220RecruitingPhase 1/Phase 2
Testing IRL757 for apathy in Parkinson's disease
This trial tests a new drug called IRL757 to see if it is safe and helps with apathy (loss of motivation or interest) in people with Parkinson's disease. You need to have at least moderate apathy and a caregiver who can come to visits with you.
PlevenAges 50–90 - NCT07457710Recruiting
Remote haptic rehab for Parkinson's disease
This study tests a remote therapy program that uses gentle vibrations (haptic feedback) to help people with Parkinson's disease improve their movement and coordination. You can participate from home, as long as you have mild to moderate Parkinson's.
Blacksburg, VirginiaAges 18 years+ - NCT06733077Recruiting
Digital services for Parkinson's disease
This study is developing digital services for people with Parkinson's disease and also includes healthy volunteers. It aims to understand movement problems like freezing of gait and festination, and uses a virtual reality system to measure these issues.
ExeterAges 18 years+ - NCT07441915Recruiting
Sleep Sounds and Brain Training for Parkinson's with Mild Memory Problems
This trial tests whether playing soft sounds during sleep can boost the effects of a computer-based brain training program in people with Parkinson's disease who have mild memory or thinking issues. If you qualify, you'll use a headband that plays tones while you sleep and do brain exercises for several weeks.
Zurich, Canton of ZurichAges 18 years+ - NCT07440563Enrolling by invitation
Vagus nerve stimulation with rehab for Parkinson's
This trial tests if combining a gentle ear nerve stimulation with physical therapy can improve symptoms of Parkinson's disease. It might help people who can walk on their own and have stable medication.
Ankara, Please SelectAges 40 years+ - NCT07432958RecruitingPhase 2
Study of AP-472 with levodopa for Parkinson's motor fluctuations
This trial tests an experimental drug called AP-472, taken alongside your regular Parkinson's medications, to see if it can reduce the amount of "OFF" time you experience each day when symptoms return between doses of levodopa.
Little Rock, ArkansasAges 30–80 - NCT07434089Recruiting
Walking therapy and gut health in Parkinson's
This trial tests how a special treadmill (C-Mill) training affects the connection between your brain and gut in Parkinson's disease. It may help improve walking and gut symptoms.
Messina, MessinaAges 40–70 - NCT07427498Recruiting
How beliefs affect hallucinations in Parkinson's disease
This study looks at how your past experiences and expectations might influence visual hallucinations if you have Parkinson's disease. It involves cognitive tests and compares people with and without hallucinations, as well as healthy volunteers.
GrenobleAges 18–85 - NCT04735627Recruiting
Real-time monitoring of levodopa levels in Parkinson’s
This study checks whether measuring levodopa (a Parkinson medicine) in real time can help better understand Parkinson medication effects. You may be asked to wear/perform study monitoring while taking your usual carbidopa/levodopa tablets.
San Diego, CaliforniaAges 40–85
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Common questions
- Are there clinical trials for parkinsonism?
- Yes. Clin2 currently lists 732 recruiting parkinsonism studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a parkinsonism trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a parkinsonism trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.