Clinical trials
Parkinson’s disease clinical trials
A movement disorder caused by the loss of dopamine-producing brain cells. We’re tracking 722 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT05981261Recruiting
Experimental pain study in Parkinson's and healthy adults
This study looks at how people with Parkinson’s, treated either with levodopa or deep brain stimulation (DBS), and healthy volunteers experience pain. The goal is to understand how Parkinson’s treatments affect pain perception.
AarhusAges Any age - NCT07134634Recruiting
Vibrating therapy ball for tremor relief
This trial tests whether a vibrating ball can help reduce tremor and make daily tasks easier. It is for people with different types of tremor, as long as they don't have major thinking problems or certain other health issues.
Beelitz, BrandenburgAges Any age - NCT06450418Recruiting
Digital app for speech and health monitoring
This trial tests a digital app that tracks speech and health changes. It is open to people with certain neurological conditions, their caregivers, and healthy volunteers.
EdinburghAges 16 years+ - NCT06329453Recruiting
Gut immunity and brain health study
This study looks at how your gut's immune system relates to brain and nerve diseases. Researchers will collect samples during a colonoscopy to better understand connections between gut health and neurologic conditions like multiple sclerosis or Parkinson's disease.
North Haven, ConnecticutAges 18–99 - NCT04664634RecruitingPhase 3
Digital treatment for drooling and swallowing in Parkinson’s
This trial tests a smartphone/tablet digital program meant to help with drooling (sialorrhea) and swallowing problems in people with Parkinson’s disease. If you’re eligible, you’ll use the platform during clinic study visits to see whether it can improve symptoms and safety.
Evanston, IllinoisAges 22 years+ - NCT04239079Recruiting
Study of immune-related changes in Parkinson’s and Alzheimer’s
This study looks for “autoimmune-like” (immune-system) features in brain-related diseases such as Parkinson’s and Alzheimer’s, using genetic testing and other assessments. Results may help researchers understand what drives these conditions and who might be more likely to have immune-related changes.
New York, New YorkAges 55–90 - NCT06193252Recruiting
Exercising to slow Parkinson's in iRBD
This study tests whether a specific amount of exercise can slow the development of Parkinson's disease in people who have a sleep condition called iRBD. If you have iRBD and are not very active, researchers will help you start a personalized exercise program and track your progress with a smartphone app.
Nijmegen, GelderlandAges 50 years+ - NCT07187843Recruiting
Parkinson's type study: brain-first vs body-first
This study looks at how Parkinson's disease affects thinking, movement, and brain health differently depending on whether it starts in the brain or the body first. Participants will have tests and scans to track these differences over time.
Reggio EmiliaAges 18 years+ - NCT07092995Enrolling by invitation
Understanding freezing of gait in Parkinson's using VR and brain signals
This study uses virtual reality and brain recordings from your DBS device to understand why some people with Parkinson's experience freezing of gait (feeling like your feet are stuck to the ground). You'll be asked to walk in a safe VR environment while researchers monitor your brain activity.
Los Angeles, CaliforniaAges 18 years+ - NCT06576713Recruiting
Genome and RNA sequencing for genetic diagnosis of early Parkinsonism
This study uses advanced genetic testing (genome and RNA sequencing) to find the genetic causes of Parkinsonism that starts before age 40 or runs in families. If you join, you will provide a blood sample and a small skin biopsy to help researchers understand your condition better.
Strasbourg, Grand EstAges 18 years+ - NCT03836950RecruitingPhase 1/Phase 2
Brain stimulation to improve thinking in Parkinson’s
This trial studies a noninvasive treatment called rTMS to help improve thinking and memory in people with Parkinson’s who have mild cognitive problems. It may help strengthen brain function, but it also has strict safety and eligibility rules to protect against seizure and metal-related risks.
Chicago, IllinoisAges 50 years+ - NCT03945968Recruiting
Risk scores after abdominal surgery for people with health conditions
This study looks at how other health problems affect the chance of postoperative complications after abdominal surgery. It aims to help doctors better predict risk and decide on the safest care for you.
ArkhangelskAges 18 years+ - NCT07839793RecruitingPhase 4
Using a device and app for Parkinson's medication
This study tests a new way to take your Parkinson's medication using a special device and an app, with the goal of making it easier to manage your symptoms. You'll use the device for 12 weeks and share your experiences through questionnaires.
Stockholm, Stockholm CountyAges 30 years+ - NCT07662837Recruiting
Comparing Tai Chi and Qi Gong for Early Parkinson's
This study compares two gentle mind-body exercises, Tai Chi and Qi Gong, to see which one better helps people with early-stage Parkinson's disease. If you are between 50 and 65 and have stable medication, you may join to find out if these practices can improve your balance, movement, and well-being.
Lahore, Punjab ProvinceAges 50–65 - NCT05820074Recruiting
Neural signals and walking changes in Parkinson’s patients
This study measures brain and nerve “biomarkers” to understand how Parkinson’s affects walking and balance. It may help researchers identify signs that relate to gait problems, and participants with a specific implanted stimulator may be able to take part in testing with stimulation turned off.
Vitznau, Canton of LucerneAges 18 years+ - NCT06615115Recruiting
Focus instructions for balance in Parkinson's rehab
This study looks at whether different types of instructions (like focusing on your movements) can help improve balance for people with Parkinson's. It might help you move better and feel more steady.
IstanbulAges 50–70 - NCT07390825Recruiting
Water therapy for daily living and movement in Parkinson's
This study tests if aquatic therapy (exercises in water) can improve walking, balance, posture, pain, and daily activities for people with Parkinson's. It aims to see if water-based exercise helps more than standard care.
Çankaya, AnkaraAges 40–80 - NCT06482502Recruiting
Testing arm function in Parkinson's with a ring and board test
This study checks if a 6-minute pegboard and ring test is a valid way to measure arm function in people with Parkinson's. It may help find better ways to track arm movement issues.
IstanbulAges 45–75 - NCT05395624RecruitingPhase 1/Phase 2
Safety imaging study of a PET tracer in ALS, Alzheimer, MS, Parkinson
This early-phase study tests the safety of a radioactive tracer (“18F-OP-801”) and how the tracer moves through the body (biodistribution) in people with ALS, Alzheimer’s disease, multiple sclerosis, Parkinson’s disease, and in healthy volunteers. It also measures how the body processes the tracer (“pharmacokinetics”) to support future studies.
San Francisco, CaliforniaAges 18–80 - NCT06885541Recruiting
Measuring internal tremors in Parkinson's patients
This study uses a device on your body to detect internal tremors (tiny vibrations you may feel inside) in Parkinson's disease. It helps researchers understand these tremors better and compare them to people without Parkinson's.
Toulouse, OccitanieAges 18–80 - NCT06791902Recruiting
Adaptive brain stimulation for walking problems in Parkinson's
This study tests a new type of deep brain stimulation (DBS) that automatically adjusts to your walking or balance issues. It uses your brain's own signals to improve movement.
Lausanne, Canton of VaudAges 18 years+ - NCT06479083Recruiting
Parkinson's telemedicine support and treatment study
This study uses telemedicine to help coordinate care for people with Parkinson's disease or related conditions. It aims to improve treatment and support across different doctors and services.
HomburgAges 30–85 - NCT06467695Recruiting
Low voltage brain stimulation for depression in Parkinson's
This study tests whether a gentle, low-voltage electrical stimulation (tDCS) can help improve depression in people with Parkinson's disease. It involves coming to the lab for sessions where a small device sends a mild current to your brain, and you'll also have an EEG (a non-invasive brain wave recording).
Mobile, AlabamaAges 19–65 - NCT04706910RecruitingPhase 3
PET scan study to optimize imaging in several diseases
This trial improves a special PET scan (a type of brain/body imaging) using 18F-DOPA, to better show how certain conditions behave in the body. If you or your child may have one of the listed conditions, the study may help your doctors get clearer scan results.
Edmonton, AlbertaAges Any age
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Common questions
- Are there clinical trials for parkinson’s disease?
- Yes. Clin2 currently lists 722 recruiting parkinson’s disease studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a parkinson’s disease trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a parkinson’s disease trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.