Clinical trials
Parkinson’s disease clinical trials
A movement disorder caused by the loss of dopamine-producing brain cells. We’re tracking 723 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT06872203Enrolling by invitation
Sensing brain signals with new DBS leads during surgery
This study tests a new way to measure brain signals during Deep Brain Stimulation (DBS) surgery for Parkinson's disease. It uses special leads that can sense brain activity, which may help doctors better adjust the stimulation in the future.
Aurora, ColoradoAges 18–75 - NCT06707402Recruiting
Community walking program for people with Parkinson's
This study tests whether a 24-week community walking program (brisk walking) can help people with Parkinson's disease who have trouble walking. If you join, you will walk regularly with others in your community and have your walking ability checked before and after.
Aarhus CAges 40 years+ - NCT06834191Recruiting
Parkinson's and immunosuppressant drugs study
This study looks at how taking immunosuppressive medicines affects the course of Parkinson's disease. It compares people with Parkinson's who have been on these drugs for over a year to those who have never taken them regularly.
WarsawAges Any age - NCT06817772Enrolling by invitation
Digital markers for movement in Parkinson's disease
This trial uses smartphone sensors to track movement in people with early-to-mild Parkinson's disease. It aims to find digital markers that help doctors better monitor symptoms and adjust treatments.
Madrid, MadridAges 30–80 - NCT06823921Enrolling by invitation
Exercise and thinking in Parkinson's disease
This study tests whether high-intensity interval training (HIIT) can improve thinking skills in people with Parkinson's. If you are willing to exercise in a group, this trial might help you understand the benefits of exercise.
New Haven, ConnecticutAges 40 years+ - NCT06819020Enrolling by invitation
Adaptive deep brain stimulation for freezing of gait in Parkinson's
This trial tests an adaptive deep brain stimulation (DBS) system designed to improve freezing of gait in Parkinson’s disease. It is for people who still have trouble walking despite medications and are already planning to have DBS surgery.
San Francisco, CaliforniaAges 21–75 - NCT06809400RecruitingPhase 1
Study of LY4006896 for Parkinson's disease
This study tests an investigational drug called LY4006896 in healthy people and in people with Parkinson's disease. It aims to see if the drug is safe and how it affects the body, which may help in developing a new treatment for Parkinson's.
Los Alamitos, CaliforniaAges 30–85 - NCT06142448Recruiting
Walking tricks for better gait in Parkinson's
This study tests whether using simple walking tricks (like stepping over lines or listening to a beat) can help people with Parkinson's improve their walking. If you haven't already been using these tricks daily, you may be able to join and see if they help you.
NijmegenAges 18 years+ - NCT06765668RecruitingPhase 4
Study of CREXONT for Parkinson's with wearing-off episodes
This study tests how well CREXONT, an extended-release form of carbidopa-levodopa, controls symptoms in people with Parkinson's who experience predictable 'off' periods when their regular medication wears off. The goal is to see if it can reduce the daily hours of poor mobility.
Phoenix, ArizonaAges 18 years+ - NCT06750224Enrolling by invitation
Alexander vs Feldenkrais for Parkinson's Disease
This study compares two gentle movement re-education methods—the Alexander Technique and Feldenkrais Method—to see which helps improve movement and balance in people with Parkinson's. If you are in early to moderate stages and can stand and walk, you may be able to join.
Lahore, Punjab ProvinceAges 50–70 - NCT06719583Recruiting
Black and African Americans Connections to Parkinson's Disease
This study is building a research registry to learn more about how Parkinson's disease affects Black and African American communities. If you have Parkinson's or are a healthy volunteer, you can join by giving a saliva sample for genetic research.
Birmingham, AlabamaAges 18 years+ - NCT05800470Recruiting
Brain-training with light sensors to improve walking in Parkinson’s
This trial tests a “neurofeedback” training program using a special light-sensing cap (fNIRS) to help improve balance and walking in people with Parkinson’s disease. You may also do guided walking practice mentally (imagery training), and your ability to walk and balance will be measured.
Taipei, None SelectedAges 40–85 - NCT06692920Recruiting
Parkinson's brain signals study during DBS surgery
This study looks at brain signals in people with Parkinson's who are already scheduled for Deep Brain Stimulation (DBS) surgery. The goal is to better understand how certain brain pathways work, which could lead to improved treatments.
Minneapolis, MinnesotaAges 21–75 - NCT05982730Recruiting
Segway training for balance and thinking in Parkinson's
This study tests whether practicing balance on a Segway can improve walking and thinking for people with moderate Parkinson's. You will train on a Segway while getting special sensory cues, and researchers will see if it helps your motor skills and cognitive function.
Dallas, TexasAges 50–85 - NCT06642454Enrolling by invitation
Breathing-guided nerve stimulation for Parkinson's disease
This study tests a type of nerve stimulation (vagus nerve) for Parkinson's disease. It compares a method that uses your breathing cycle to deliver stimulation versus standard stimulation. The goal is to see which works better for movement and non-movement symptoms.
Hefei, AnhuiAges 40–80 - NCT06630702Recruiting
Spinal cord stimulation for freezing gait in advanced Parkinson's
This trial tests if a small device placed near your spine (spinal cord stimulation) can help improve freezing of gait in people with advanced Parkinson's whose medicines aren't enough. It also aims to reduce leg pain if you have it.
Hsinchu, Hsinchu CityAges 40–85 - NCT06618157Enrolling by invitation
Brain stimulation study for Parkinson's tremor
This study tests a new way to adjust deep brain stimulation (DBS) for Parkinson's disease. It focuses on people who still have at least mild tremor after their DBS device has been in place for three months or more, to see if targeting specific brain connections can help improve tremor control.
Durham, North CarolinaAges 18 years+ - NCT06518824Recruiting
Theta brain stimulation to boost thinking in Parkinson's
This study tests whether a special pattern of deep brain stimulation (called theta bursts) can improve thinking and memory in people with Parkinson's disease. It's for patients who already have a DBS device in their brain that is at least 3 months old.
Vancouver, British ColumbiaAges 18–80 - NCT06506058Recruiting
Study on balance and brain in Parkinson's freezing of gait
This study looks at how the balance system and brain work together to cause freezing of gait in Parkinson's disease. By understanding these factors, researchers hope to find better ways to help people walk more steadily.
Minneapolis, MinnesotaAges 21–80 - NCT06466525RecruitingPhase 1
Testing LBT-3627 for safety in healthy adults and people with Parkinson's
This study tests an investigational drug called LBT-3627 to see if it is safe and how the body processes it. It includes healthy volunteers and people with Parkinson's disease, and may help determine if the drug could be a future treatment.
Melbourne, VictoriaAges 30–89 - NCT06464029Recruiting
Balance and walking study in Parkinson's disease
This study looks at balance problems in people with Parkinson's disease. It uses simple tests to understand what causes trouble with standing and walking, which may help find better treatments.
Minneapolis, MinnesotaAges 45–80 - NCT06455293RecruitingPhase 2
Psilocybin therapy for depression in Parkinson's disease
This study tests whether psilocybin, a substance found in certain mushrooms, can help improve depression in people with Parkinson's disease. If you have Parkinson's and are feeling depressed, this treatment may offer a new option.
San Francisco, CaliforniaAges 40–80 - NCT06422208Enrolling by invitationPhase 1
Parkinson's cell transplant trial using your own cells
This trial tests whether transplanting special dopamine-producing cells made from a patient's own skin cells can help treat Parkinson's disease. It is for people who have had Parkinson's for at least 5 years and still respond well to medication.
Boston, MassachusettsAges 55–80 - NCT06416345Recruiting
Cue2Walk: Freezing detection and cues for Parkinson's walking
This study tests whether a new device called Cue2Walk can help people with Parkinson's disease who have freezing of gait. The device detects when you freeze and sends a signal (like a beep) to help you start walking again. Researchers want to see if it is worth the cost compared to your usual care.
Nijmegen, GelderlandAges Any age
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Common questions
- Are there clinical trials for parkinson’s disease?
- Yes. Clin2 currently lists 723 recruiting parkinson’s disease studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a parkinson’s disease trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a parkinson’s disease trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.