Clinical trials
Peripheral Neuropathic Pain clinical trials
Below are recruiting peripheral neuropathic pain clinical trials, each written for real people, not researchers. We’re tracking 78 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT06628908RecruitingPhase 3
Study of suzetrigine for painful diabetic nerve damage
This trial tests an experimental medicine called suzetrigine to see if it can safely reduce pain caused by nerve damage from diabetes (diabetic peripheral neuropathy). It might be an option if you have had daily pain in both legs and current treatments haven't worked well enough.
Anniston, AlabamaAges 18–80 - NCT06614322RecruitingPhase 2
Nerve damage foot pain study
This study tests whether certain pain medicines can better relieve foot pain caused by nerve damage. It compares how people's bodies respond to pain to find the best treatment for each person.
Boston, MassachusettsAges 18–80 - NCT06443281Recruiting
Understanding pain after spinal cord injury or nerve damage
This study is looking at how people with spinal cord injuries or peripheral neuropathy (nerve damage outside the spine) experience pain. The goal is to better understand the different types of pain, which could help doctors create more personalized treatments in the future.
Zurich, Canton of ZurichAges 18–80 - NCT05864053RecruitingPhase 1/Phase 2
Ketamine medicine trial for chronic nerve pain in adults
This Phase 1/2 study tests hydroxynorketamine (a related ketamine-type medicine) to see if it can reduce chronic nerve pain in the arms or legs. You may be able to join if you have nerve pain for more than 3 months and meet safety and health check requirements.
Chicago, IllinoisAges 18–75 - NCT05404581Recruiting
Insula brain stimulation for long-term nerve pain
This trial tests whether stimulating a specific brain area (the insula) can reduce chronic nerve pain. It is for people whose pain has lasted at least 6 months and has not improved enough with several pain medicines and other procedures.
Charlottesville, VirginiaAges 18–80 - NCT05351801RecruitingPhase 2
Test cannabis-based treatment for nerve pain
This Phase 2 study tests cannabis-derived products to see if they reduce neuropathic (nerve-related) pain in veterans. It may help people whose pain is persistent and causes significant daily impact, especially if certain exam tests show allodynia (pain from normally non-painful touch).
San Diego, CaliforniaAges 21 years+ - NCT04299893RecruitingPhase 2/Phase 3
Ozone treatment for chemotherapy nerve pain
This trial tests whether ozone therapy can reduce painful nerve damage caused by chemotherapy. It is for adults with ongoing moderate-to-severe pain in the hands or feet after chemotherapy.
Las Palmas de Gran Canaria, Las PalmasAges 18–100 - NCT07712913RecruitingPhase 3
Pregabalin for nerve pain from diabetes or shingles
This trial tests an extended-release version of pregabalin (a pain medication) for people with long-term nerve pain caused by diabetes or shingles. It aims to see if this once-daily pill can reduce pain with fewer side effects.
Salvador, Estado de BahiaAges 18–75 - NCT07298408RecruitingPhase 1/Phase 2
CBD for Diabetic Nerve Pain: A Pilot Study
This trial tests whether a daily dose of CBD (a cannabis compound) can help reduce nerve pain from type 2 diabetes. It's a small, early study to see if it's safe and effective.
Tallahassee, FloridaAges 40–70 - NCT07154056Recruiting
Spinal cord stimulation for stubborn nerve pain
This trial tests a new type of spinal cord stimulation for people with long-term nerve pain that hasn't improved with other treatments. The goal is to see if this special stimulation pattern can reduce pain better than standard care.
Poitiers, FranceAges 18–80 - NCT07301632RecruitingPhase 2
MDMA for severe chronic nerve pain
This trial tests if MDMA, combined with psychotherapy, can help people with severe chronic nerve pain that hasn't improved with standard treatments. You'll receive either MDMA or a placebo to see if it safely reduces pain and improves your quality of life.
Toronto, OntarioAges 18 years+ - NCT06129890Recruiting
Brain stimulation for nerve pain and depression
This trial tests whether a noninvasive brain stimulation technique (rTMS) can help people with long-term nerve pain who also have depression. It aims to see if this treatment can reduce pain and improve mood.
Saint-EtienneAges 18–85 - NCT06726954Recruiting
Magnetic brain stimulation for spinal cord injury pain
This study tests whether a magnetic treatment called repetitive transcranial magnetic stimulation (rTMS) can help reduce nerve pain that some people have after a spinal cord injury. rTMS uses painless magnetic pulses to gently stimulate the brain, and it may help change how your brain processes pain.
AfyonkarahisarAges 18–75 - NCT07304401Recruiting
Closed-loop spinal cord stimulation for chemo-related nerve pain
This trial tests whether a new type of spinal cord stimulator (SCS) can reduce pain caused by chemotherapy. If you have lasting nerve pain after cancer treatment and standard pain medications haven't helped, this device might offer relief.
ArnhemAges 18 years+ - NCT05295498Recruiting
Brain stimulation trial for nerve pain relief
This trial studies whether repeated magnetic stimulation of the brain can reduce ongoing nerve pain. It may help people whose nerve pain has been steady for at least a month and who still need pain medicine more than once a week.
KrakowAges 18 years+ - NCT06361108RecruitingPhase 1
Spray study for diabetic nerve pain in feet
This study tests a new spray medication (YJ001) applied to the feet to see if it is safe and helps reduce pain in people with diabetic peripheral neuropathy. You may qualify if you have diabetes, stable blood sugar, and moderate to severe nerve pain in your feet.
Fredericksburg, TexasAges 18–80 - NCT06155916Recruiting
Sleep and nerve pain: a pregabalin study
This study tests whether a nerve pain medication (pregabalin) helps people with long-term nerve pain sleep better. It involves brain scans to see how the medication affects the brain.
Helsinki, HUSAges 18–75 - NCT07187219Recruiting
TMS for nerve pain in cancer patients
This trial tests if repetitive transcranial magnetic stimulation (rTMS), a non-invasive brain stimulation, can reduce chronic nerve pain caused by cancer or its treatment. It may help patients who have not found relief from standard pain medications.
Saint-EtienneAges 18–85 - NCT07427537Recruiting
Studying nerve damage from chemotherapy in colorectal and lung cancer patients
This study looks for small molecules in the blood that might predict nerve damage caused by certain chemotherapies. If you have colorectal or lung cancer and are starting a specific chemo plan, this trial could help researchers understand why some people get nerve problems and others don't.
Clermont-FerrandAges 18 years+ - NCT05492188Recruiting
Testing training and skin reflex changes for nerve pain after SCI
This study looks at how a training program affects skin reflexes and nerve pain in people with spinal cord injury (SCI). It may help researchers find better ways to manage nerve pain by changing how the body responds to touch and training.
Charleston, South CarolinaAges 18 years+ - NCT07061769Enrolling by invitation
Using a gentle head device to help with nerve pain from chemo
This trial tests a low-intensity cranial PEMF device to see if it can reduce nerve pain caused by chemotherapy. Participants use the device at home and receive text messages to track their symptoms.
Newport Beach, CaliforniaAges 18–60 - NCT07650526Recruiting
Brain Stimulation for Nerve Pain Relief
This study tests two types of magnetic brain stimulation (aiTBS and rTMS) to treat long-lasting nerve pain. Researchers want to see which approach works better and develop a way to predict who will benefit most.
Boulogne-Billancourt, Île-de-France RegionAges 18–80 - NCT06420141Recruiting
Nerve pain after ankle fracture surgery
This study looks at why some people develop nerve pain (neuropathic pain) after breaking their ankle and having surgery. If you have an ankle fracture that needs surgery, you may be able to join and help researchers understand this type of pain better.
Indianapolis, IndianaAges 18–85 - NCT07260656RecruitingEarly Phase 1
Capsaicin cream for diabetic nerve foot pain
This trial tests a new cream (Capsadyn®) made from chili pepper extract to see if it can reduce nerve pain in the feet caused by diabetes. If it works, it could offer a simple treatment you apply at home.
Roanoke, VirginiaAges 25–75
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Common questions
- Are there clinical trials for peripheral neuropathic pain?
- Yes. Clin2 currently lists 78 recruiting peripheral neuropathic pain studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a peripheral neuropathic pain trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a peripheral neuropathic pain trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.